Publications 2020

580 publications

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.
Lehmann LC, Bacic L, Hewitt G, ..., Boulton SJ, Deindl S
Cell Rep 33 (12) 108529 [2020-12-22; online 2020-12-29]
Cryo-EM [Service]
Life-Threatening COVID-19: Defective Interferons Unleash Excessive Inflammation.
Zhang Q, Bastard P, Bolze A, ..., Abel L, Casanova JL
Med 1 (1) 14-20 [2020-12-18; online 2020-12-29]
Cellular Immunomonitoring [Collaborative]
Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.
Winklemann I, Matsuoka R, Meier PF, ..., Beckstein O, Drew D
EMBO J. 39 (24) e105908 [2020-12-15; online 2020-10-29]
Cryo-EM [Service]
Association between inflammasome-related polymorphisms and psoriatic arthritis.
Juneblad K, Kastbom A, Johansson L, ..., Söderkvist P, Alenius GM
Scand. J. Rheumatol. - (-) 1-7 [2020-12-10; online 2020-12-10]
Clinical Genomics Linköping
Reaction Wood Anatomical Traits and Hormonal Profiles in Poplar Bent Stem and Root.
De Zio E, Montagnoli A, Karady M, ..., Chiatante D, Trupiano D
Front Plant Sci 11 (-) 590985 [2020-12-07; online 2020-12-07]
Swedish Metabolomics Centre (SMC) [Service]
Resolution enhancement in NMR spectra by deconvolution with compressed sensing reconstruction.
Kazimierczuk K, Kasprzak P, Georgoulia PS, ..., Westenhoff S, Orekhov VY
Chem. Commun. (Camb.) 56 (93) 14585-14588 [2020-12-04; online 2020-11-04]
Swedish NMR Centre (SNC) [Collaborative]
Genetic Predisposition to Coronary Artery Disease in Type 2 Diabetes Mellitus.
van Zuydam NR, Ladenvall C, Voight BF, ..., Palmer CNA, SUMMIT Steering Committee; CARDIOGRAMplusC4D Steering Committee*
Circ Genom Precis Med 13 (6) e002769 [2020-12-00; online 2020-08-13]
NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
A workflow for high-throughput screening, data analysis, processing, and hit identification
Hansel CS, Yousefian S, Klemm AH, Carreras-Puigvert J
KNIME blog https://www.knime.com/blog/a-workflow-for-high-throughput-screening-data-analysis-processing-and-hit-identification (-) - [2020-11-30; online 2020-06-19]
BioImage Informatics [Technology development]
TrackMate: My favorite image analysis tool, by Neubias members
Klemm A
Wiley Analytical Science https://analyticalscience.wiley.com/do/10.1002/was.000400044 (-) - [2020-11-30; online 2020-05-26]
BioImage Informatics [Service]
α-Synuclein promotes IAPP fibril formation in vitro and β-cell amyloid formation in vivo in mice.
Mucibabic M, Steneberg P, Lidh E, ..., Lindahl E, Edlund H
Sci Rep 10 (1) 20438 [2020-11-24; online 2020-11-24]
Cryo-EM [Service]
Cryo‐EM structure of native human uromodulin, a zona pellucida module polymer
Stsiapanava A, Xu C, Brunati M, ..., Wu B, Jovine L
EMBO J - (-) e106807 [2020-11-16; online 2020-11-16]
Cryo-EM [Collaborative]
Autoantibodies against type I IFNs in patients with life-threatening COVID-19.
Bastard P, Rosen LB, Zhang Q, ..., Su HC, Casanova JL
Science 370 (6515) - [2020-10-23; online 2020-09-24]
Cellular Immunomonitoring [Collaborative]
A high-stringency blueprint of the human proteome.
Adhikari S, Nice EC, Deutsch EW, ..., Aebersold R, Baker MS
Nat Commun 11 (1) 5301 [2020-10-16; online 2020-10-16]
Affinity Proteomics Stockholm [Collaborative]
Discovery of USP7 small-molecule allosteric inhibitors.
Engström O, Belda O, Kullman-Magnusson M, ..., Parkes KEB, Zhao H
Bioorg. Med. Chem. Lett. 30 (20) 127471 [2020-10-15; online 2020-08-08]
Swedish NMR Centre (SNC) [Service]
Exploring the bacterial nano-universe.
Söderholm N, Singh B, Uhlin BE, Sandblad L
Curr. Opin. Struct. Biol. 64 (-) 166-173 [2020-10-00; online 2020-08-23]
Cryo-EM [Collaborative]
MAIT cell activation and dynamics associated with COVID-19 disease severity.
Parrot T, Gorin JB, Ponzetta A, ..., Strålin K, Sandberg JK
Sci Immunol 5 (51) - [2020-09-28; online 2020-09-30]
Affinity Proteomics Stockholm [Service]
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.
Bailey MH, Meyerson WU, Dursi LJ, ..., Ding L, PCAWG Consortium
Nat Commun 11 (1) 4748 [2020-09-21; online 2020-09-21]
Clinical Genomics Uppsala [Service]
Prenylated Flavonoids from the Roots of Tephrosia rhodesica.
Atilaw Y, Muiva-Mutisya L, Bogaerts J, ..., Erdélyi M, Yenesew A
J. Nat. Prod. 83 (8) 2390-2398 [2020-08-28; online 2020-08-13]
Swedish NMR Centre (SNC) [Service]
Sex differences in oncogenic mutational processes.
Li CH, Prokopec SD, Sun RX, ..., Boutros PC, PCAWG Consortium
Nat Commun 11 (1) 4330 [2020-08-28; online 2020-08-28]
Clinical Genomics Uppsala [Service]
µ Opioid Receptor Agonism for L-DOPA-Induced Dyskinesia in Parkinson's Disease.
Bezard E, Li Q, Hulme H, ..., Andren PE, Crossman AR
J. Neurosci. 40 (35) 6812-6819 [2020-08-26; online 2020-07-20]
Spatial Mass Spectrometry [Service]
Natural killer cell immunotypes related to COVID-19 disease severity.
Maucourant C, Filipovic I, Ponzetta A, ..., Björkström NK, Karolinska COVID-19 Study Group
Sci Immunol 5 (50) eabd6832 [2020-08-21; online 2020-08-23]
Affinity Proteomics Stockholm [Service] Bioinformatics Compute and Storage [Service]
13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking.
Yang M, Safavi S, Woodward EL, ..., Nord KH, Paulsson K
Blood 136 (8) 946-956 [2020-08-20; online 2020-05-10]
Clinical Genomics Lund
Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.
Škerlová J, Unterlass J, Göttmann M, ..., Jemth AS, Stenmark P
J. Biol. Chem. 295 (33) 11656-11668 [2020-08-14; online 2020-06-22]
Protein Science Facility (PSF) [Service]
SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS.
Malcovati L, Stevenson K, Papaemmanuil E, ..., Hellstrom-Lindberg E, Cazzola M
Blood 136 (2) 157-170 [2020-07-09; online 2020-04-30]
Clinical Genomics Uppsala [Service]
Serum Metabolites in Hand-Arm Vibration Exposed Workers.
Vihlborg P, Graff P, Hagenbjörk A, ..., Bryngelsson IL, Eriksson K
J Occup Environ Med 62 (7) 460-465 [2020-07-00; online 2020-07-31]
Swedish Metabolomics Centre (SMC) [Service]
Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA.
Baronti L, Guzzetti I, Ebrahimi P, ..., Chen AA, Petzold K
Nature 583 (7814) 139-144 [2020-07-00; online 2020-05-27]
Protein Science Facility (PSF) [Service]
High content drug screening for Fanconi anemia therapeutics.
Montanuy H, Camps-Fajol C, Carreras-Puigvert J, ..., Minguillón J, Surrallés J
Orphanet J Rare Dis 15 (1) 170 [2020-06-30; online 2020-06-30]
Drug Discovery and Development (DDD)
Chanjo: Clincal grade sequence coverage analysis
Andeer R, Magnusson M, Wedell A, Stranneheim H
F1000Res 9 (-) 615 [2020-06-16; online 2020-06-16]
Clinical Genomics Stockholm [Technology development]
Fungi and Oomycetes in the Irrigation Water of Forest Nurseries
Marčiulynas A, Marčiulynienė D, Lynikienė J, ..., Vaičiukynė M, Menkis A
Forests 11 (4) 459 [2020-04-18; online 2020-04-18]
NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]
Difference in virulence between Neisseria meningitidis serogroups W and Y in transgenic mice.
Eriksson L, Stenmark B, Deghmane AE, ..., Mölling P, Taha MK
BMC Microbiol. 20 (1) 92 [2020-04-15; online 2020-04-15]
Clinical Genomics Örebro
Genetic Associations Between Childhood Psychopathology and Adult Depression and Associated Traits in 42 998 Individuals: A Meta-Analysis.
Akingbuwa WA, Hammerschlag AR, Jami ES, ..., Middeldorp CM, and the Bipolar Disorder and Major Depressive Disorder Working Groups of the Psychiatric Genomics Consortium
JAMA Psychiatry - (-) - [2020-04-15; online 2020-04-15]
NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]
Genomic characterization and outcome of prosthetic joint infections caused by Staphylococcus aureus.
Wildeman P, Tevell S, Eriksson C, ..., Söderquist B, Stenmark B
Sci Rep 10 (1) 5938 [2020-04-03; online 2020-04-03]
Clinical Genomics Örebro
MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.
Scaletti ER, Vallin KS, Bräutigam L, ..., Stenmark P, Jemth AS
J. Biol. Chem. - (-) - [2020-03-06; online 2020-03-06]
Protein Science Facility (PSF) [Service]
Exosomes influence the behavior of human mesenchymal stem cells on titanium surfaces.
Wang X, Shah FA, Vazirisani F, ..., Ekström K, Thomsen P
Biomaterials 230 (-) 119571 [2020-02-00; online 2019-10-24]
Glycoproteomics [Service]
Evolution of a new function by fusion between phage DNA and a bacterial gene.
Warsi O, Knopp M, Surkov S, Hultqvist JJ, Andersson DI
Mol. Biol. Evol. - (-) - [2020-01-16; online 2020-01-16]
Glycoproteomics [Service]
Proteomic analysis of follicular fluid during human ovulation.
Zakerkish F, Brännström M, Carlsohn E, ..., van der Post S, Thoroddsen A
Acta Obstet Gynecol Scand - (-) - [2020-01-16; online 2020-01-16]
Glycoproteomics [Service]
Identification of novel diagnostic and prognostic biomarkers for abdominal aortic aneurysm.
Memon AA, Zarrouk M, Ågren-Witteschus S, ..., Gottsäter A, Sundquist K
Eur J Prev Cardiol 27 (2) 132-142 [2020-01-00; online 2019-08-29]
Clinical Biomarkers [Service]
Regulation of α-synuclein by chaperones in mammalian cells.
Burmann BM, Gerez JA, Matečko-Burmann I, ..., Riek R, Hiller S
Nature 577 (7788) 127-132 [2020-01-00; online 2019-12-04]
Swedish NMR Centre (SNC) [Service]
A Chemical Screen Identifies a Link between Lipid Metabolism and mRNA Translation
Corman A, Kanellis DC, Häggblad M, ..., Carreras-Puigvert J, Fernandez-Capetillo O
SSRN Journal - (-) - [2020-00-00; online 2020-00-00]
Chemical Biology Consortium Sweden (CBCS) [Service]
Regeneration of water-deactivated Cu/SAPO-34(MO) with acids
Woo J, Bernin D, Ahari H, ..., Zammit M, Olsson L
Catal. Sci. Technol. 10 (5) 1539-1550 [2020-00-00; online 2020-00-00]
Swedish NMR Centre (SNC)