Clinical Genomics Linköping

A landscape of X-inactivation during human T cell development.

Gylemo B, Bensberg M, Hennings V, ..., Ekwall O, Nestor CE

Nat Commun 15 (1) 10527 [2024-12-04; online 2024-12-04]

Duloxetine enhances PAX6 expression and suppresses innate immune responses in murine LPS-induced corneal inflammation.

Moustardas P, Abbasi M, Javidjam D, ..., Aberdam D, Lagali N

Ocul Surf 34 (-) 225-234 [2024-10-00; online 2024-08-08]

Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.

Bojmar L, Zambirinis CP, Hernandez JM, ..., Jarnagin WR, Lyden D

Nat. Med. 30 (8) 2170-2180 [2024-08-00; online 2024-06-28]

A DNA Methylation Signature from Buccal Swabs to Identify Tuberculosis Infection.

Karlsson L, Öhrnberg I, Sayyab S, ..., Paues J, Lerm M

J. Infect. Dis. - (-) - [2024-07-04; online 2024-07-04]

NOS2-derived low levels of NO drive psoriasis pathogenesis.

Köhler I, Bivik Eding C, Kasic NK, Verma D, Enerbäck C

Cell Death Dis 15 (6) 449 [2024-06-26; online 2024-06-26]

Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids.

Rademaekers M, Johansson EO, Johansson E, Roberg K, Wiechec E

Cancer Cell Int 24 (1) 190 [2024-05-31; online 2024-05-31]

Exhaustive identification of genome-wide binding events of transcriptional regulators.

Nordin A, Pagella P, Zambanini G, Cantù C

Nucleic Acids Res. 52 (7) e40 [2024-04-24; online 2024-03-19]

MicroRNA-155 mediates multiple gene regulations pertinent to the role of human adipose-derived mesenchymal stem cells in skin regeneration.

Shahin H, Belcastro L, Das J, ..., Elmasry M, El-Serafi AT

Front Bioeng Biotechnol 12 (-) 1328504 [2024-03-18; online 2024-03-18]

Prognostic value of hypoxia-responsive gene expression profile in patients diagnosed with head and neck squamous cell carcinoma.

Matic N, Pettersson L, Sellebjerg F, ..., Roberg K, Wiechec E

Transl Oncol 39 (-) 101841 [2024-01-00; online 2023-11-27]

Year 2023

Modified N-acyl-L-homoserine lactone compounds abrogate Las-dependent quorum-sensing response in human pathogen Pseudomonas aeruginosa.

Ballante F, Turkina MV, Ntzouni M, Magnusson KE, Vikström E

Front Mol Biosci 10 (-) 1264773 [2023-10-16; online 2023-10-16]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Clinical Genomics Linköping [Service]

Genome-wide DNA methylation profiling in Lyme neuroborreliosis reveals altered methylation patterns of HLA genes.

Henningsson AJ, Hellberg S, Lerm M, Sayyab S

J. Infect. Dis. - (-) - [2023-10-12; online 2023-10-12]

Selected β-glucans act as immune-training agents by improving anti-mycobacterial activity in human macrophages - a pilot study.

Braian C, Karlsson L, Das J, Lerm M

J Innate Immun 15 (1) 751-764 [2023-09-21; online 2023-09-21]

Epigenetic modifications appear in the human placenta following anxiety and depression during pregnancy.

Martinez CA, Marteinsdottir I, Josefsson A, ..., Theodorsson E, Rodriguez-Martinez H

Placenta 140 (-) 72-79 [2023-09-07; online 2023-08-01]

Differential DNA Methylation of MicroRNA-Encoding Genes in Psoriatic Epidermis Highlights the Wnt Pathway.

Verma D, Kasic NK, Jeppsson F, ..., Das J, Enerbäck C

J. Invest. Dermatol. 143 (8) 1594-1597.e14 [2023-08-00; online 2023-02-27]

Domain landscapes of somatic NF1 mutations in pheochromocytoma and paraganglioma.

Tabebi M, Frikha F, Volpe M, Gimm O, Söderkvist P

Gene 872 (-) 147432 [2023-07-01; online 2023-04-14]

Mating modifies the expression of crucial oxidative-reductive transcripts in the pig oviductal sperm reservoir: is the female ensuring sperm survival?

Álvarez-Rodríguez M, Roca J, Martínez EA, Rodríguez-Martínez H

Front Endocrinol (Lausanne) 14 (-) 1042176 [2023-06-07; online 2023-06-07]

Stress-sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis.

Örkenby L, Skog S, Ekman H, ..., Nätt D, Öst A

Mol. Syst. Biol. 19 (5) e11148 [2023-05-09; online 2023-03-20]

methylR: a graphical interface for comprehensive DNA methylation array data analysis.

Volpe M, Das J

Bioinformatics 39 (4) - [2023-04-03; online 2023-04-12]

Clinical Genomics Linköping [Technology development]

Ahlberg E, Martí M, Govindaraj D, ..., Jenmalm MC, Tingö L

Pediatr Allergy Immunol 34 (4) e13952 [2023-04-00; online 2023-04-27]

miRNome and Proteome Profiling of Human Keratinocytes and Adipose Derived Stem Cells Proposed miRNA-Mediated Regulations of Epidermal Growth Factor and Interleukin 1-Alpha.

Shahin H, Abdallah S, Das J, ..., Elmasry M, El-Serafi AT

Int J Mol Sci 24 (5) - [2023-03-04; online 2023-03-04]

Nuclear and mitochondrial DNA alterations in pheochromocytomas and paragangliomas, and their potential treatment.

Tabebi M, Söderkvist P, Gimm O

Endocr. Relat. Cancer 30 (1) - [2023-01-01; online 2022-12-08]

Year 2022

A new cut&run low volume-urea (LoV-U) protocol optimized for transcriptional co-factors uncovers Wnt/b-catenin tissue-specific genomic targets.

Zambanini G, Nordin A, Jonasson M, Pagella P, Cantù C

Development - (-) - [2022-11-10; online 2022-11-10]

Case report: Two sisters with a germline CHEK2 variant and distinct endocrine neoplasias.

Vallera RD, Ding Y, Hatanpaa KJ, ..., Dahia PLM, Ghayee HK

Front Endocrinol (Lausanne) 13 (-) 1024108 [2022-11-07; online 2022-11-07]

The oncogenic transcription factor FOXQ1 is a differential regulator of Wnt target genes.

Pizzolato G, Moparthi L, Söderholm S, Cantù C, Koch S

J. Cell. Sci. 135 (19) - [2022-10-01; online 2022-10-10]

Implementing precision medicine in a regionally organized healthcare system in Sweden.

Fioretos T, Wirta V, Cavelier L, ..., Edsjö A, Rosenquist R

Nat. Med. 28 (10) 1980-1982 [2022-10-00; online 2022-09-20]

Clinical Genomics Gothenburg [Collaborative] Clinical Genomics Linköping [Service] Clinical Genomics Stockholm [Collaborative] Clinical Genomics Umeå [Service] Clinical Genomics Uppsala [Collaborative]

Methylation associated with long- or short-term survival in glioblastoma patients from the Nordic phase 3 trial.

Łysiak M, Das J, Malmström A, Söderkvist P

Front Genet 13 (-) 934519 [2022-08-25; online 2022-08-25]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Linköping [Service]

Autosomal recessive congenital hereditary corneal dystrophy associated with a novel SLC4A11 mutation in two consanguineous Tunisian families.

Chibani Z, Abid IZ, Söderkvist P, Feki J, Aifa MH

Br J Ophthalmol 106 (2) 281-287 [2022-02-00; online 2021-04-20]

Genetic Alterations in Mitochondrial DNA Are Complementary to Nuclear DNA Mutations in Pheochromocytomas.

Tabebi M, Łysiak M, Dutta RK, ..., Gimm O, Söderkvist P

Cancers (Basel) 14 (2) - [2022-01-06; online 2022-01-06]

Loss of SDHB Induces a Metabolic Switch in the hPheo1 Cell Line toward Enhanced OXPHOS.

Tabebi M, Kumar Dutta R, Skoglund C, Söderkvist P, Gimm O

Int J Mol Sci 23 (1) - [2022-01-05; online 2022-01-05]

Year 2021

Increased diagnostic sensitivity of palpation-guided thyroid nodule fine-needle aspiration cytology by BRAF V600E-mutation analysis.

Gimm O, Ivansson K, Beka E, ..., Garvin S, Söderkvist P

J Pathol Clin Res 7 (6) 556-564 [2021-11-00; online 2021-06-22]

5´XP sRNA-seq: efficient identification of transcripts with and without 5´ phosphorylation reveals evolutionary conserved small RNA.

Kugelberg U, Nätt D, Skog S, Kutter C, Öst A

RNA Biol 18 (11) 1588-1599 [2021-11-00; online 2020-12-31]

Genetic Variant Score and Arrhythmogenic Right Ventricular Cardiomyopathy Phenotype in Plakophilin-2 Mutation Carriers.

Svensson A, Platonov PG, Haugaa KH, ..., Svendsen JH, Gunnarsson C

Cardiology 146 (6) 763-771 [2021-09-01; online 2021-09-01]

EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene.

Somasundaram R, Jensen CT, Tingvall-Gustafsson J, ..., Ungerbäck J, Sigvardsson M

Blood 137 (22) 3037-3049 [2021-06-03; online 2021-02-24]

B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors.

Strid T, Okuyama K, Tingvall-Gustafsson J, ..., Ungerbäck J, Sigvardsson M

J. Immunol. 206 (11) 2700-2713 [2021-06-01; online 2021-05-21]

Complement-Opsonized HIV Modulates Pathways Involved in Infection of Cervical Mucosal Tissues: A Transcriptomic and Proteomic Study.

Svanberg C, Ellegård R, Crisci E, ..., Shankar EM, Larsson M

Front Immunol 12 (-) 625649 [2021-05-20; online 2021-05-20]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Linköping [Service]

X-chromosome variants are associated with aldosterone producing adenomas.

Dutta RK, Larsson M, Arnesen T, ..., Gimm O, Söderkvist P

Sci Rep 11 (1) 10562 [2021-05-18; online 2021-05-18]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Genomics Linköping [Service]

Association between inflammasome-related polymorphisms and psoriatic arthritis.

Juneblad K, Kastbom A, Johansson L, ..., Söderkvist P, Alenius G

Scand. J. Rheumatol. 50 (3) 206-212 [2021-05-00; online 2020-12-10]

Deletions on Chromosome Y and Downregulation of the SRY Gene in Tumor Tissue Are Associated with Worse Survival of Glioblastoma Patients.

Łysiak M, Smits A, Roodakker KR, ..., Söderkvist P, Malmström A

Cancers (Basel) 13 (7) - [2021-03-31; online 2021-03-31]

Sex Disparities in MGMT Promoter Methylation and Survival in Glioblastoma: Further Evidence from Clinical Cohorts.

Smits A, Lysiak M, Magnusson A, ..., Söderkvist P, Malmström A

J Clin Med 10 (4) - [2021-02-03; online 2021-02-03]

Year 2020

Activation of RAS Signalling is Associated with Altered Cell Adhesion in Phaeochromocytoma.

Rossitti HM, Dutta RK, Larsson C, ..., Söderkvist P, Gimm O

Int J Mol Sci 21 (21) 8072 [2020-10-29; online 2020-10-29]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Linköping [Service]

ABCB1 single-nucleotide variants and survival in patients with glioblastoma treated with radiotherapy concomitant with temozolomide.

Malmström A, Łysiak M, Åkesson L, ..., Green H, Söderkvist P

Pharmacogenomics J. 20 (2) 213-219 [2020-04-00; online 2019-10-17]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Linköping [Service]

Do we really know who has an MGMT methylated glioma? Results of an international survey regarding use of MGMT analyses for glioma.

Malmström A, Łysiak M, Kristensen BW, ..., Henriksson R, Söderkvist P

Neurooncol Pract 7 (1) 68-76 [2020-01-00; online 2019-09-24]

Year 2019

Novel BEST1 gene mutations associated with two different forms of macular dystrophy in Tunisian families.

Chibani Z, Abid IZ, Molbaek A, ..., Feki J, Hmani-Aifa M

Clin Exp Ophthalmol 47 (8) 1063-1073 [2019-11-00; online 2019-07-24]

Assessment of genetic and non-genetic risk factors for venous thromboembolism in glioblastoma - The predictive significance of B blood group.

Heenkenda MK, Malmström A, Lysiak M, ..., Uppugunduri S, Osman A

Thromb. Res. 183 (-) 136-142 [2019-11-00; online 2019-10-22]

A somatic mutation in CLCN2 identified in a sporadic aldosterone-producing adenoma.

Dutta RK, Arnesen T, Heie A, ..., Söderkvist P, Gimm O

Eur. J. Endocrinol. 181 (5) K37-K41 [2019-11-00; online 2019-09-07]

The science of librarianship. University of Wales at Aberystwyth, July 31, 1917.

Year 2012

PubMed

Osler W

J Med Libr Assoc 100 (4 Suppl) A [2012-10-00; online 2013-03-21]