Sci Adv

ISSN	2375-2548
ISSN-L	2375-2548
IUID	857318422126485d8eaf5e0c23adfb35
Modified	2020-11-27T13:14:10.068Z
Created	2017-05-09T09:12:19.165Z

Year 2024

PubMed DOI Crossref

Five centuries of consanguinity, isolation, health, and conflict in Las Gobas: A Northern Medieval Iberian necropolis.

Rodríguez-Varela R, Yaka R, Pochon Z, ..., Azkarate A, Götherström A

Sci Adv 10 (35) eadp8625 [2024-08-30; online 2024-08-28]

Ancient DNA [Collaborative] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Origin, structure, and composition of the spider major ampullate silk fiber revealed by genomics, proteomics, and single-cell and spatial transcriptomics.

Sonavane S, Hassan S, Chatterjee U, ..., Reimegård J, Rising A

Sci Adv 10 (33) eadn0597 [2024-08-16; online 2024-08-14]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Short read [Service] NGI Spatial omics [Collaborative] NGI Stockholm (Genomics Applications) [Collaborative] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Service]

PubMed DOI Crossref

AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1.

Díaz-Holguín A, Saarinen M, Vo DD, ..., Carlsson J, Svenningsson P

Sci Adv 10 (32) eadn1524 [2024-08-09; online 2024-08-07]

Drug Discovery and Development (DDD) [Service]

PubMed DOI Crossref

Magnesium induced structural reorganization in the active site of adenylate kinase.

Nam K, Thodika ARA, Tischlik S, ..., Sauer-Eriksson AE, Wolf-Watz M

Sci Adv 10 (32) eado5504 [2024-08-09; online 2024-08-09]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1.

Gustavsson EK, Sethi S, Gao Y, ..., Hardy J, Ryten M

Sci Adv 10 (26) eadk1296 [2024-06-28; online 2024-06-26]

Clinical Genomics Lund [Service]

DOI Crossref

MOXD1 is a lineage-specific gene and a tumor suppressor in neuroblastoma

Fredlund E, Andersson S, Hilgert E, ..., van Nes J, Mohlin S

Sci Adv 10 (25) - [2024-06-21; online 2024-06-21]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Adaptive introgression reveals the genetic basis of a sexually selected syndrome in wall lizards.

Feiner N, Yang W, Bunikis I, While GM, Uller T

Sci Adv 10 (14) eadk9315 [2024-04-05; online 2024-04-03]

NGI Long read [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

Year 2023

PubMed DOI Crossref

LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification.

Garza R, Atacho DAM, Adami A, ..., Douse CH, Jakobsson J

Sci Adv 9 (44) eadh9543 [2023-11-03; online 2023-11-01]

Clinical Genomics Lund [Service] NGI Long read [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Decoding pancreatic endocrine cell differentiation and β cell regeneration in zebrafish.

Mi J, Liu KC, Andersson O

Sci Adv 9 (33) eadf5142 [2023-08-18; online 2023-08-18]

NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis.

Clifton LA, Wacklin-Knecht HP, Ådén J, ..., Sparrman T, Gröbner G

Sci Adv 9 (22) eadg7940 [2023-06-02; online 2023-06-02]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Large-scale phylogenomics of aquatic bacteria reveal molecular mechanisms for adaptation to salinity.

Jurdzinski KT, Mehrshad M, Delgado LF, ..., Bertilsson S, Andersson AF

Sci Adv 9 (21) eadg2059 [2023-05-26; online 2023-05-26]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis.

Thomas OG, Bronge M, Tengvall K, ..., Olsson T, Kockum I

Sci Adv 9 (20) eadg3032 [2023-05-19; online 2023-05-17]

Autoimmunity and Serology Profiling [Service]

PubMed DOI Crossref

Warmer temperatures favor slower-growing bacteria in natural marine communities.

Abreu CI, Dal Bello M, Bunse C, Pinhassi J, Gore J

Sci Adv 9 (19) eade8352 [2023-05-10; online 2023-05-10]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Evidence for a single, ancient origin of a genus-wide alternative life history strategy.

Tunström K, Woronik A, Hanly JJ, ..., Martin A, Wheat CW

Sci Adv 9 (12) eabq3713 [2023-03-22; online 2023-03-22]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Year 2022

PubMed DOI Crossref

Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases.

Verma A, Åberg-Zingmark E, Sparrman T, ..., Sauer-Eriksson E, Wolf-Watz M

Sci Adv 8 (44) eabm4089 [2022-11-04; online 2022-11-04]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

A genomic snapshot of demographic and cultural dynamism in Upper Mesopotamia during the Neolithic Transition.

Altınışık NE, Kazancı DD, Aydoğan A, ..., Erim Özdoğan A, Somel M

Sci Adv 8 (44) eabo3609 [2022-11-04; online 2022-11-04]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance.

Mañas A, Aaltonen K, Andersson N, ..., Gisselsson D, Bexell D

Sci Adv 8 (43) eabq4617 [2022-10-28; online 2022-10-28]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes.

Pillon NJ, Smith JAB, Alm PS, ..., Krook A, Zierath JR

Sci Adv 8 (36) eabo3192 [2022-09-09; online 2022-09-07]

Spatial Proteomics [Service]

PubMed DOI Crossref

PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.

Toskas K, Yaghmaeian-Salmani B, Skiteva O, ..., Perlmann T, Holmberg J

Sci Adv 8 (34) eabo1543 [2022-08-26; online 2022-08-26]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Uncovering the genomic basis of an extraordinary plant invasion.

Bieker VC, Battlay P, Petersen B, ..., Hodgins KA, Martin MD

Sci Adv 8 (34) eabo5115 [2022-08-26; online 2022-08-24]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Rapid adaptive radiation of Darwin's finches depends on ancestral genetic modules.

Rubin CJ, Enbody ED, Dobreva MP, ..., Grant PR, Andersson L

Sci Adv 8 (27) eabm5982 [2022-07-08; online 2022-07-08]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Touch signaling and thigmomorphogenesis are regulated by complementary CAMTA3- and JA-dependent pathways.

Darwish E, Ghosh R, Ontiveros-Cisneros A, ..., Khan K, Van Aken O

Sci Adv 8 (20) eabm2091 [2022-05-20; online 2022-05-20]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.

Bronge M, Högelin KA, Thomas OG, ..., Olsson T, Grönlund H

Sci Adv 8 (17) eabn1823 [2022-04-29; online 2022-04-27]

Autoimmunity and Serology Profiling [Collaborative]

PubMed DOI Crossref

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies.

Hanke L, Sheward DJ, Pankow A, ..., McInerney GM, Murrell B

Sci Adv 8 (12) eabm0220 [2022-03-25; online 2022-03-25]

Structural Proteomics [Collaborative]

PubMed DOI Crossref

Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow.

Le Duc D, Velluva A, Cassatt-Johnstone M, ..., Shapiro B, Schöneberg T

Sci Adv 8 (5) eabl6496 [2022-02-04; online 2022-02-04]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.

Chaptal V, Zampieri V, Wiseman B, ..., Boumendjel A, Falson P

Sci Adv 8 (4) eabg9215 [2022-01-28; online 2022-01-26]

Cryo-EM [Service]

Year 2021

PubMed DOI Crossref

Structural basis of DegP protease temperature-dependent activation.

Šulskis D, Thoma J, Burmann BM

Sci Adv 7 (50) eabj1816 [2021-12-10; online 2021-12-08]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Causal effects of inflammatory protein biomarkers on inflammatory diseases.

Ek WE, Karlsson T, Höglund J, Rask-Andersen M, Johansson Å

Sci Adv 7 (50) eabl4359 [2021-12-10; online 2021-12-08]

Affinity Proteomics Uppsala [Service]

PubMed DOI Crossref

Tracking the ATP-binding response in adenylate kinase in real time.

Orädd F, Ravishankar H, Goodman J, ..., Wolf-Watz M, Andersson M

Sci Adv 7 (47) eabi5514 [2021-11-19; online 2021-11-17]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

The role of H3K36 methylation and associated methyltransferases in chromosome-specific gene regulation.

Lindehell H, Glotov A, Dorafshan E, Schwartz YB, Larsson J

Sci Adv 7 (40) eabh4390 [2021-10-00; online 2021-10-01]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.

Kanellis DC, Espinoza JA, Zisi A, ..., Lindström MS, Bartek J

Sci Adv 7 (32) - [2021-08-00; online 2021-08-04]

Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication.

Jiang M, Xie X, Zhu X, ..., Larsson NG, Falkenberg M

Sci Adv 7 (27) - [2021-07-00; online 2021-07-02]

Integrated Microscopy Technologies Gothenburg [Service]

PubMed DOI Crossref

A single-cell type transcriptomics map of human tissues.

Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C

Sci Adv 7 (31) eabh2169 [2021-07-00; online 2021-07-28]

Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative]

PubMed DOI Crossref

Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.

Michno W, Stringer KM, Enzlein T, ..., Edwards FA, Hanrieder J

Sci Adv 7 (25) - [2021-06-00; online 2021-06-16]

Integrated Microscopy Technologies Gothenburg [Collaborative]

PubMed DOI Crossref

Direct observation of hyperpolarization breaking through the spin diffusion barrier.

Stern Q, Cousin SF, Mentink-Vigier F, ..., Cala O, Jannin S

Sci Adv 7 (18) - [2021-04-00; online 2021-04-30]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters.

Schober FA, Moore D, Atanassov I, ..., Freyer C, Wredenberg A

Sci Adv 7 (8) - [2021-02-00; online 2021-02-19]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia.

Fridjonsdottir E, Shariatgorji R, Nilsson A, ..., Bezard E, Andrén PE

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

Spatial Mass Spectrometry [Technology development]

PubMed DOI Crossref

Human population dynamics and Yersinia pestis in ancient northeast Asia.

Kılınç GM, Kashuba N, Koptekin D, ..., Storå J, Götherström A

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure

PubMed DOI Crossref

The structure of enteric human adenovirus 41-A leading cause of diarrhea in children.

Rafie K, Lenman A, Fuchs J, ..., Arnberg N, Carlson LA

Sci Adv 7 (2) - [2021-01-00; online 2021-01-08]

Cryo-EM [Service] Glycoproteomics and MS Proteomics [Collaborative]

Year 2020

PubMed DOI Crossref

A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells.

Dias JM, Alekseenko Z, Jeggari A, ..., Iber D, Ericson J

Sci Adv 6 (38) - [2020-09-00; online 2020-09-16]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor.

Köhler C, Carlström G, Gunnarsson A, ..., Edman K, Akke M

Sci Adv 6 (29) eabb5277 [2020-07-00; online 2020-07-17]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena.

Westbury MV, Hartmann S, Barlow A, ..., Heller R, Hofreiter M

Sci Adv 6 (11) eaay0456 [2020-03-00; online 2020-03-13]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death.

Busker S, Qian W, Haraldsson M, ..., Tamm KP, Page BDG

Sci Adv 6 (12) eaax7945 [2020-03-00; online 2020-03-20]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Protein Science Facility (PSF) [Service]

Year 2019

PubMed DOI Crossref

Genomic architecture of parallel ecological divergence: Beyond a single environmental contrast.

Morales HE, Faria R, Johannesson K, ..., Westram AM, Butlin RK

Sci Adv 5 (12) eaav9963 [2019-12-00; online 2019-12-04]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Multiplexed analysis of the secretin-like GPCR-RAMP interactome.

Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP

Sci Adv 5 (9) eaaw2778 [2019-09-00; online 2019-09-18]

Affinity Proteomics Stockholm [Collaborative]

PubMed DOI Crossref

Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain

Bigalke JM, Aibara S, Roth R, ..., Amunts A, Sandmark J

Sci Adv 5 (7) eaau4202 [2019-07-05; online 2019-07-05]

Cryo-EM [Service]

PubMed DOI Crossref

Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution.

Hill J, Rastas P, Hornett EA, ..., Nylin S, Wheat CW

Sci Adv 5 (6) eaau3648 [2019-06-00; online 2019-06-12]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Pervasive hybridizations in the history of wheat relatives.

Glémin S, Scornavacca C, Dainat J, ..., David J, Ranwez V

Sci Adv 5 (5) eaav9188 [2019-05-00; online 2019-05-01]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service]

Year 2018

PubMed DOI Crossref

Ancient genomes suggest the eastern Pontic-Caspian steppe as the source of western Iron Age nomads.

Krzewińska M, Kılınç GM, Juras A, ..., Storå J, Götherström A

Sci Adv 4 (10) eaat4457 [2018-10-00; online 2018-10-03]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Cedernaes J, Schönke M, Westholm JO, ..., Zierath JR, Benedict C

Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

Year 2017

PubMed DOI Crossref

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.

Deville C, Carroni M, Franke KB, ..., Mogk A, Saibil HR

Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]

Cryo-EM [Service]

Year 2016

PubMed DOI Crossref

Analysis of neural crest-derived clones reveals novel aspects of facial development.

Kaucka M, Ivashkin E, Gyllborg D, ..., Hellander A, Adameyko I

Sci Adv 2 (8) e1600060 [2016-08-00; online 2016-08-03]

Integrated Microscopy Technologies Stockholm [Collaborative]