Sci Adv

ISSN	2375-2548
ISSN-L	2375-2548
IUID	857318422126485d8eaf5e0c23adfb35
Modified	2020-11-27T13:14:10.068Z
Created	2017-05-09T09:12:19.165Z

DOI Crossref

Dephosphorylation and ion binding in prokaryotic calcium transport

Prabudiansyah I, Orädd F, Magkakis K, ..., Levantino M, Andersson M

Sci Adv 10 (41) - [2024-10-11; online 2024-10-11]

Cryo-EM [Service]

PubMed DOI Crossref

Five centuries of consanguinity, isolation, health, and conflict in Las Gobas: A Northern Medieval Iberian necropolis.

Rodríguez-Varela R, Yaka R, Pochon Z, ..., Azkarate A, Götherström A

Sci Adv 10 (35) eadp8625 [2024-08-30; online 2024-08-28]

Ancient DNA [Collaborative] Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Origin, structure, and composition of the spider major ampullate silk fiber revealed by genomics, proteomics, and single-cell and spatial transcriptomics.

Sonavane S, Hassan S, Chatterjee U, ..., Reimegård J, Rising A

Sci Adv 10 (33) eadn0597 [2024-08-16; online 2024-08-14]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Short read [Service] NGI Spatial omics [Collaborative] NGI Stockholm (Genomics Applications) [Collaborative] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Reprogramming Yarrowia lipolytica metabolism for efficient synthesis of itaconic acid from flask to semipilot scale.

Fu J, Zaghen S, Lu H, ..., Di Bartolomeo F, Kerkhoven EJ

Sci Adv 10 (32) eadn0414 [2024-08-09; online 2024-08-09]

Chalmers Mass Spectrometry Infrastructure [Service]

PubMed DOI Crossref

AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1.

Díaz-Holguín A, Saarinen M, Vo DD, ..., Carlsson J, Svenningsson P

Sci Adv 10 (32) eadn1524 [2024-08-09; online 2024-08-07]

Drug Discovery and Development (DDD) [Service]

PubMed DOI Crossref

Magnesium induced structural reorganization in the active site of adenylate kinase.

Nam K, Thodika ARA, Tischlik S, ..., Sauer-Eriksson AE, Wolf-Watz M

Sci Adv 10 (32) eado5504 [2024-08-09; online 2024-08-09]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1.

Gustavsson EK, Sethi S, Gao Y, ..., Hardy J, Ryten M

Sci Adv 10 (26) eadk1296 [2024-06-28; online 2024-06-26]

Clinical Genomics Lund [Service]

DOI Crossref

MOXD1 is a lineage-specific gene and a tumor suppressor in neuroblastoma

Fredlund E, Andersson S, Hilgert E, ..., van Nes J, Mohlin S

Sci Adv 10 (25) - [2024-06-21; online 2024-06-21]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Adaptive introgression reveals the genetic basis of a sexually selected syndrome in wall lizards.

Feiner N, Yang W, Bunikis I, While GM, Uller T

Sci Adv 10 (14) eadk9315 [2024-04-05; online 2024-04-03]

Bioinformatics Support for Computational Resources [Service] NGI Long read [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

PubMed DOI Crossref

LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification.

Garza R, Atacho DAM, Adami A, ..., Douse CH, Jakobsson J

Sci Adv 9 (44) eadh9543 [2023-11-03; online 2023-11-01]

Clinical Genomics Lund [Service] NGI Long read [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Decoding pancreatic endocrine cell differentiation and β cell regeneration in zebrafish.

Mi J, Liu KC, Andersson O

Sci Adv 9 (33) eadf5142 [2023-08-18; online 2023-08-18]

NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis.

Clifton LA, Wacklin-Knecht HP, Ådén J, ..., Sparrman T, Gröbner G

Sci Adv 9 (22) eadg7940 [2023-06-02; online 2023-06-02]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Large-scale phylogenomics of aquatic bacteria reveal molecular mechanisms for adaptation to salinity.

Jurdzinski KT, Mehrshad M, Delgado LF, ..., Bertilsson S, Andersson AF

Sci Adv 9 (21) eadg2059 [2023-05-26; online 2023-05-26]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Cross-reactive EBNA1 immunity targets alpha-crystallin B and is associated with multiple sclerosis.

Thomas OG, Bronge M, Tengvall K, ..., Olsson T, Kockum I

Sci Adv 9 (20) eadg3032 [2023-05-19; online 2023-05-17]

Autoimmunity and Serology Profiling [Service]

PubMed DOI Crossref

Warmer temperatures favor slower-growing bacteria in natural marine communities.

Abreu CI, Dal Bello M, Bunse C, Pinhassi J, Gore J

Sci Adv 9 (19) eade8352 [2023-05-10; online 2023-05-10]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Evidence for a single, ancient origin of a genus-wide alternative life history strategy.

Tunström K, Woronik A, Hanly JJ, ..., Martin A, Wheat CW

Sci Adv 9 (12) eabq3713 [2023-03-22; online 2023-03-22]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Endoreplication mediates cell size control via mechanochemical signaling from cell wall.

Ma Y, Jonsson K, Aryal B, ..., Hamant O, Bhalerao RP

Sci Adv 8 (49) eabq2047 [2022-12-09; online 2022-12-09]

Cryo-EM [Service]

PubMed DOI Crossref

Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases.

Verma A, Åberg-Zingmark E, Sparrman T, ..., Sauer-Eriksson E, Wolf-Watz M

Sci Adv 8 (44) eabm4089 [2022-11-04; online 2022-11-04]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

A genomic snapshot of demographic and cultural dynamism in Upper Mesopotamia during the Neolithic Transition.

Altınışık NE, Kazancı DD, Aydoğan A, ..., Erim Özdoğan A, Somel M

Sci Adv 8 (44) eabo3609 [2022-11-04; online 2022-11-04]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance.

Mañas A, Aaltonen K, Andersson N, ..., Gisselsson D, Bexell D

Sci Adv 8 (43) eabq4617 [2022-10-28; online 2022-10-28]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes.

Pillon NJ, Smith JAB, Alm PS, ..., Krook A, Zierath JR

Sci Adv 8 (36) eabo3192 [2022-09-09; online 2022-09-07]

Spatial Proteomics [Service]

PubMed DOI Crossref

PRC2-mediated repression is essential to maintain identity and function of differentiated dopaminergic and serotonergic neurons.

Toskas K, Yaghmaeian-Salmani B, Skiteva O, ..., Perlmann T, Holmberg J

Sci Adv 8 (34) eabo1543 [2022-08-26; online 2022-08-26]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Uncovering the genomic basis of an extraordinary plant invasion.

Bieker VC, Battlay P, Petersen B, ..., Hodgins KA, Martin MD

Sci Adv 8 (34) eabo5115 [2022-08-26; online 2022-08-24]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Rapid adaptive radiation of Darwin's finches depends on ancestral genetic modules.

Rubin CJ, Enbody ED, Dobreva MP, ..., Grant PR, Andersson L

Sci Adv 8 (27) eabm5982 [2022-07-08; online 2022-07-08]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Touch signaling and thigmomorphogenesis are regulated by complementary CAMTA3- and JA-dependent pathways.

Darwish E, Ghosh R, Ontiveros-Cisneros A, ..., Khan K, Van Aken O

Sci Adv 8 (20) eabm2091 [2022-05-20; online 2022-05-20]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Identification of four novel T cell autoantigens and personal autoreactive profiles in multiple sclerosis.

Bronge M, Högelin KA, Thomas OG, ..., Olsson T, Grönlund H

Sci Adv 8 (17) eabn1823 [2022-04-29; online 2022-04-27]

Autoimmunity and Serology Profiling [Collaborative]

PubMed DOI Crossref

Multivariate mining of an alpaca immune repertoire identifies potent cross-neutralizing SARS-CoV-2 nanobodies.

Hanke L, Sheward DJ, Pankow A, ..., McInerney GM, Murrell B

Sci Adv 8 (12) eabm0220 [2022-03-25; online 2022-03-25]

Structural Proteomics [Collaborative]

PubMed DOI Crossref

Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow.

Le Duc D, Velluva A, Cassatt-Johnstone M, ..., Shapiro B, Schöneberg T

Sci Adv 8 (5) eabl6496 [2022-02-04; online 2022-02-04]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Substrate-bound and substrate-free outward-facing structures of a multidrug ABC exporter.

Chaptal V, Zampieri V, Wiseman B, ..., Boumendjel A, Falson P

Sci Adv 8 (4) eabg9215 [2022-01-28; online 2022-01-26]

Cryo-EM [Service]

PubMed DOI Crossref

Structural basis of DegP protease temperature-dependent activation.

Šulskis D, Thoma J, Burmann BM

Sci Adv 7 (50) eabj1816 [2021-12-10; online 2021-12-08]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Causal effects of inflammatory protein biomarkers on inflammatory diseases.

Ek WE, Karlsson T, Höglund J, Rask-Andersen M, Johansson Å

Sci Adv 7 (50) eabl4359 [2021-12-10; online 2021-12-08]

Affinity Proteomics Uppsala [Service]

PubMed DOI Crossref

Tracking the ATP-binding response in adenylate kinase in real time.

Orädd F, Ravishankar H, Goodman J, ..., Wolf-Watz M, Andersson M

Sci Adv 7 (47) eabi5514 [2021-11-19; online 2021-11-17]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

The role of H3K36 methylation and associated methyltransferases in chromosome-specific gene regulation.

Lindehell H, Glotov A, Dorafshan E, Schwartz YB, Larsson J

Sci Adv 7 (40) eabh4390 [2021-10-00; online 2021-10-01]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.

Kanellis DC, Espinoza JA, Zisi A, ..., Lindström MS, Bartek J

Sci Adv 7 (32) - [2021-08-00; online 2021-08-04]

Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

The mitochondrial single-stranded DNA binding protein is essential for initiation of mtDNA replication.

Jiang M, Xie X, Zhu X, ..., Larsson NG, Falkenberg M

Sci Adv 7 (27) - [2021-07-00; online 2021-07-02]

Integrated Microscopy Technologies Gothenburg [Service]

PubMed DOI Crossref

A single-cell type transcriptomics map of human tissues.

Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C

Sci Adv 7 (31) eabh2169 [2021-07-00; online 2021-07-28]

Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative]

PubMed DOI Crossref

Following spatial Aβ aggregation dynamics in evolving Alzheimer's disease pathology by imaging stable isotope labeling kinetics.

Michno W, Stringer KM, Enzlein T, ..., Edwards FA, Hanrieder J

Sci Adv 7 (25) - [2021-06-00; online 2021-06-16]

Integrated Microscopy Technologies Gothenburg [Collaborative]

PubMed DOI Crossref

Direct observation of hyperpolarization breaking through the spin diffusion barrier.

Stern Q, Cousin SF, Mentink-Vigier F, ..., Cala O, Jannin S

Sci Adv 7 (18) - [2021-04-00; online 2021-04-30]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

The one-carbon pool controls mitochondrial energy metabolism via complex I and iron-sulfur clusters.

Schober FA, Moore D, Atanassov I, ..., Freyer C, Wredenberg A

Sci Adv 7 (8) - [2021-02-00; online 2021-02-19]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia.

Fridjonsdottir E, Shariatgorji R, Nilsson A, ..., Bezard E, Andrén PE

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

Spatial Mass Spectrometry [Technology development]

PubMed DOI Crossref

Human population dynamics and Yersinia pestis in ancient northeast Asia.

Kılınç GM, Kashuba N, Koptekin D, ..., Storå J, Götherström A

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure

PubMed DOI Crossref

The structure of enteric human adenovirus 41-A leading cause of diarrhea in children.

Rafie K, Lenman A, Fuchs J, ..., Arnberg N, Carlson LA

Sci Adv 7 (2) - [2021-01-00; online 2021-01-08]

Cryo-EM [Service] Glycoproteomics and MS Proteomics [Collaborative]

PubMed DOI Crossref

A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells.

Dias JM, Alekseenko Z, Jeggari A, ..., Iber D, Ericson J

Sci Adv 6 (38) - [2020-09-00; online 2020-09-16]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor.

Köhler C, Carlström G, Gunnarsson A, ..., Edman K, Akke M

Sci Adv 6 (29) eabb5277 [2020-07-00; online 2020-07-17]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Hyena paleogenomes reveal a complex evolutionary history of cross-continental gene flow between spotted and cave hyena.

Westbury MV, Hartmann S, Barlow A, ..., Heller R, Hofreiter M

Sci Adv 6 (11) eaay0456 [2020-03-00; online 2020-03-13]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death.

Busker S, Qian W, Haraldsson M, ..., Tamm KP, Page BDG

Sci Adv 6 (12) eaax7945 [2020-03-00; online 2020-03-20]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Protein Science Facility (PSF) [Service]

PubMed DOI Crossref

Genomic architecture of parallel ecological divergence: Beyond a single environmental contrast.

Morales HE, Faria R, Johannesson K, ..., Westram AM, Butlin RK

Sci Adv 5 (12) eaav9963 [2019-12-00; online 2019-12-04]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Multiplexed analysis of the secretin-like GPCR-RAMP interactome.

Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP

Sci Adv 5 (9) eaaw2778 [2019-09-00; online 2019-09-18]

Affinity Proteomics Stockholm [Collaborative]

PubMed DOI Crossref

Cryo-EM structure of the activated RET signaling complex reveals the importance of its cysteine-rich domain

Bigalke JM, Aibara S, Roth R, ..., Amunts A, Sandmark J

Sci Adv 5 (7) eaau4202 [2019-07-05; online 2019-07-05]

Cryo-EM [Service]

PubMed DOI Crossref

Unprecedented reorganization of holocentric chromosomes provides insights into the enigma of lepidopteran chromosome evolution.

Hill J, Rastas P, Hornett EA, ..., Nylin S, Wheat CW

Sci Adv 5 (6) eaau3648 [2019-06-00; online 2019-06-12]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Pervasive hybridizations in the history of wheat relatives.

Glémin S, Scornavacca C, Dainat J, ..., David J, Ranwez V

Sci Adv 5 (5) eaav9188 [2019-05-00; online 2019-05-01]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service]

PubMed DOI Crossref

Ancient genomes suggest the eastern Pontic-Caspian steppe as the source of western Iron Age nomads.

Krzewińska M, Kılınç GM, Juras A, ..., Storå J, Götherström A

Sci Adv 4 (10) eaat4457 [2018-10-00; online 2018-10-03]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Cedernaes J, Schönke M, Westholm JO, ..., Zierath JR, Benedict C

Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

PubMed DOI Crossref

Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase.

Deville C, Carroni M, Franke KB, ..., Mogk A, Saibil HR

Sci Adv 3 (8) e1701726 [2017-08-00; online 2017-08-04]

Cryo-EM [Service]

PubMed DOI Crossref

Analysis of neural crest-derived clones reveals novel aspects of facial development.

Kaucka M, Ivashkin E, Gyllborg D, ..., Hellander A, Adameyko I

Sci Adv 2 (8) e1600060 [2016-08-00; online 2016-08-03]

Integrated Microscopy Technologies Stockholm [Collaborative]

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