Gröbner G

Family name	Gröbner
Given name	Gerhard
Initials	G
ORCID	ORCID 0000-0001-7380-8797
Affiliations	Department of Chemistry, Umeå University, Linnaeus väg 6, 901 87, Umeå, Sweden. gerhard.grobner@chem.umu.se.

17 publications

PubMed DOI Crossref

Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis.

Clifton LA, Wacklin-Knecht HP, Ådén J, ..., Sparrman T, Gröbner G

Sci Adv 9 (22) eadg7940 [2023-06-02; online 2023-06-02]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae.

Nadeem A, Berg A, Pace H, ..., Uhlin BE, Wai SN

Elife 11 (-) - [2022-02-08; online 2022-02-08]

Cryo-EM [Service] Integrated Microscopy Technologies Umeå [Service] Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Backbone chemical shift assignment and dynamics of the N-terminal domain of ClpB from Francisella tularensis type VI secretion system.

Mushtaq AU, Ådén J, Alam A, Sjöstedt A, Gröbner G

Biomol NMR Assign - (-) - [2022-01-05; online 2022-01-05]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation.

Mushtaq AU, Ådén J, Clifton LA, ..., Sparrman T, Gröbner G

Commun Biol 4 (1) 507 [2021-04-27; online 2021-04-27]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Insight into Functional Membrane Proteins by Solution NMR: The Human Bcl-2 Protein-A Promising Cancer Drug Target.

Ul Mushtaq A, Ådén J, Sparrman T, Hedenström M, Gröbner G

Molecules 26 (5) 1467 [2021-03-08; online 2021-03-08]

Chemical Biology Consortium Sweden (CBCS) [Service] Swedish NMR Centre (SNC) [Service]

DOI Crossref

Solid-state NMR methods for studying membrane systems

Gröbner G, Williamson P

- - (-) - [2020-12-00; online 2020-12-00]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Metabolomics of Interstitial Fluid, Plasma and Urine in Patients with Arterial Hypertension: New Insights into the Underlying Mechanisms.

Chachaj A, Matkowski R, Gröbner G, Szuba A, Dudka I

Diagnostics 10 (11) 936 [2020-11-11; online 2020-11-11]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

A novel recombinant expression and purification approach for the full-length anti-apoptotic membrane protein Bcl-2.

Ådén J, Mushtaq AU, Dingeldein A, Wallgren M, Gröbner G

Protein Expression and Purification 172 (-) 105628 [2020-08-00; online 2020-03-22]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Comprehensive metabolomics analysis of prostate cancer tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status.

Dudka I, Thysell E, Lundquist K, ..., Wikström P, Gröbner G

BMC Cancer 20 (1) 437 [2020-05-18; online 2020-05-18]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Bax to the future - A novel, high-yielding approach for purification and expression of full-length Bax protein for structural studies.

Dingeldein APG, Lindberg MJ, Ådén J, ..., Stoll R, Gröbner G

Protein Expression and Purification 158 (-) 20-26 [2019-06-00; online 2019-02-06]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Oxidatively stressed mitochondria-mimicking membranes: A molecular insight into their organization during apoptosis.

Dingeldein APG, Sparrman T, Gröbner G

Biochimica et Biophysica Acta (BBA) - Biomembranes 1860 (12) 2644-2654 [2018-12-00; online 2018-10-05]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Lipid Driven Nanodomains in Giant Lipid Vesicles are Fluid and Disordered.

Koukalová A, Amaro M, Aydogan G, ..., Hof M, Šachl R

Sci Rep 7 (1) 5460 [2017-07-14; online 2017-07-14]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Apoptotic Bax at Oxidatively Stressed Mitochondrial Membranes: Lipid Dynamics and Permeabilization.

Dingeldein APG, Pokorná Š, Lidman M, ..., Hof M, Gröbner G

Biophysical Journal 112 (10) 2147-2158 [2017-05-23; online 2017-05-26]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

The oxidized phospholipid PazePC promotes permeabilization of mitochondrial membranes by Bax.

Lidman M, Pokorná Š, Dingeldein AP, ..., Hof M, Gröbner G

Biochim. Biophys. Acta 1858 (6) 1288-1297 [2016-06-00; online 2016-03-04]

Swedish NMR Centre (SNC) [Collaborative]

DOI Crossref

The Role of Lipids in Regulation of Programmed Cell Death

Lidman M, Dingeldein A, Pokorná Š, ..., Hof M, Gröbner G

Biophysical Journal 110 (3) 473a [2016-02-00; online 2016-02-00]

Swedish NMR Centre (SNC) [Collaborative]

DOI Crossref

Dynamical and Structural Alterations withing Lipid-Protein Assemblies Control Apoptotic Pore Formation - A Solid State NMR Study

Dingeldein APG, Lidman M, Sparrman T, Gröbner G

Biophysical Journal 110 (3) 59a-60a [2016-02-00; online 2016-02-00]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Inactivation of the Deg protease family in the cyanobacterium Synechocystis sp. PCC 6803 has impact on the outer cell layers.

Cheregi O, Miranda H, Gröbner G, Funk C

Journal of Photochemistry and Photobiology B: Biology 152 (Pt B) 383-394 [2015-11-00; online 2015-05-22]

Swedish NMR Centre (SNC) [Service]