Swedish Metabolomics Centre (SMC)

Differences between Arterial and Venous Umbilical Cord Plasma Metabolome and Association with Parity.

Hartvigsson O, Barman M, Savolainen O, ..., Sandberg AS, Brunius C

Metabolites 12 (2) - [2022-02-13; online 2022-02-13]

Comprehensive Peak Characterization (CPC) in Untargeted LC-MS Analysis.

Pirttilä K, Balgoma D, Rainer J, ..., Hedeland M, Brunius C

Metabolites 12 (2) - [2022-02-02; online 2022-02-02]

Swedish Metabolomics Centre (SMC) [Technology development]

Year 2021

Improved Peripheral and Hepatic Insulin Sensitivity after Lifestyle Interventions in Type 2 Diabetes Is Associated with Specific Metabolomic and Lipidomic Signatures in Skeletal Muscle and Plasma.

Chorell E, Otten J, Stomby A, ..., Svensson M, Olsson T

Metabolites 11 (12) 834 [2021-12-03; online 2021-12-03]

Physiological properties, composition and structural profiling of porcine gastrointestinal mucus.

Barmpatsalou V, Dubbelboer IR, Rodler A, ..., Pedersen BL, Bergström CAS

Eur J Pharm Biopharm 169 (-) 156-167 [2021-12-00; online 2021-10-20]

Global Proteomics and Proteogenomics [Service] Integrated Microscopy Technologies Umeå [Service] Swedish Metabolomics Centre (SMC) [Service]

Lowered nutritional quality of plankton caused by global environmental changes.

Lau DCP, Jonsson A, Isles PDF, Creed IF, Bergström AK

Glob Chang Biol 27 (23) 6294-6306 [2021-12-00; online 2021-09-30]

Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health.

Marabita F, James T, Karhu A, ..., Sallinen R, Kallioniemi O

Cell Syst - (-) - [2021-11-30; online 2021-11-30]

Autoimmunity and Serology Profiling [Service] Swedish Metabolomics Centre (SMC) [Collaborative]

Metabolomics reveals changes in metabolite profiles due to growth and metamorphosis during the ontogeny of the northern damselfly.

Späth J, Brodin T, McCallum E, ..., Fick J, Nording ML

J Insect Physiol 136 (-) 104341 [2021-11-27; online 2021-11-27]

Making complex measurements of meat composition fast: Application of rapid evaporative ionisation mass spectrometry to measuring meat quality and fraud.

Ross A, Brunius C, Chevallier O, ..., Zhang R, Vanhaecke L

Meat Sci 181 (-) 108333 [2021-11-00; online 2020-10-06]

Symptoms and oxylipins in plasma before and after exposure to rooms in which individuals have both experienced and not experienced building-related symptoms - an exploratory study.

Claeson AS, Sommar J, Liljelind I

Int J Environ Health Res - (-) 1-11 [2021-10-19; online 2021-10-19]

De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories.

Liu Q, Liu Y, Li G, ..., Chen Y, Nielsen J

Nat Commun 12 (1) 6085 [2021-10-19; online 2021-10-19]

Prediction and evaluation of the effect of pre-centrifugation sample management on the measurable untargeted LC-MS plasma metabolome.

Zheng R, Brunius C, Shi L, ..., Landberg R, Naluai ÅT

Anal. Chim. Acta 1182 (-) 338968 [2021-10-16; online 2021-08-19]

Swedish Metabolomics Centre (SMC) [Technology development]

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.

Elksnis A, Schiffer TA, Palm F, ..., Welsh N, Wang X

Clin Sci (Lond) 135 (19) 2243-2263 [2021-10-14; online 2021-09-28]

Unraveling the Metabolic Derangements Occurring in Non-infarcted Areas of Pig Hearts With Chronic Heart Failure.

Correia C, Wang QD, Linhardt G, ..., Jennbacken K, Synnergren J

Front Cardiovasc Med 8 (-) 753470 [2021-10-13; online 2021-10-13]

Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction.

Zhou X, Mikaeloff F, Curbo S, ..., Neogi U, Karlsson A

Hum. Mol. Genet. 30 (21) 2012-2026 [2021-10-13; online 2021-06-26]

Potassium transporter TRH1/KUP4 contributes to distinct auxin-mediated root system architecture responses.

Templalexis D, Tsitsekian D, Liu C, ..., Hatzopoulos P, Rigas S

Plant Physiol. - (-) - [2021-10-11; online 2021-10-11]

Broadening the roles of UDP-glycosyltransferases in auxin homeostasis and plant development.

Mateo-Bonmatí E, Casanova-Sáez R, Šimura J, Ljung K

New Phytol. 232 (2) 642-654 [2021-10-00; online 2021-08-10]

The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes.

Otten J, Stomby A, Waling M, ..., Holst JJ, Olsson T

Endocr Connect 10 (9) 1101-1110 [2021-09-09; online 2021-09-09]

Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.

Sjögren RJO, Rizo-Roca D, Chibalin AV, ..., Näslund E, Zierath JR

Diabetologia 64 (9) 2077-2091 [2021-09-00; online 2021-06-16]

Novel Microdialysis Technique Reveals a Dramatic Shift in Metabolite Secretion during the Early Stages of the Interaction between the Ectomycorrhizal Fungus Pisolithus microcarpus and Its Host Eucalyptus grandis.

Plett KL, Buckley S, Plett JM, ..., Lundberg-Felten J, Jämtgård S

Microorganisms 9 (9) - [2021-08-26; online 2021-08-26]

Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity.

Smith JAB, Savikj M, Sethi P, ..., Zierath JR, Näslund E

Am J Physiol Endocrinol Metab 321 (2) E203-E216 [2021-08-01; online 2021-06-21]

Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis.

Olsson M, Hellman U, Wixner J, Anan I

Amyloid - (-) 1-9 [2021-07-28; online 2021-07-28]

Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet.

Stenlund H, Nilholm C, Chorell E, ..., D'Amato M, Ohlsson B

Metabolites 11 (7) - [2021-07-04; online 2021-07-04]

Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction.

Tribble JR, Otmani A, Sun S, ..., Votruba M, Williams PA

Redox Biol 43 (-) 101988 [2021-07-00; online 2021-04-24]

HIV-Infected Individuals on ART With Impaired Immune Recovery Have Altered Plasma Metabolite Profiles.

Nyström S, Govender M, Yap SH, ..., Rajasuriar R, Larsson M

Open Forum Infect Dis 8 (7) ofab288 [2021-07-00; online 2021-06-02]

Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity.

Mendham AE, Goedecke JH, Zeng Y, ..., Olsson T, Chorell E

Diabetologia 64 (7) 1642-1659 [2021-07-00; online 2021-03-26]

A metabolomic study of Gomphrena agrestis in Brazilian Cerrado suggests drought-adaptive strategies on metabolism.

Melo GA, Abreu IN, de Oliveira MB, ..., Pimenta MAS, Moritz T

Sci Rep 11 (1) 12933 [2021-06-21; online 2021-06-21]

Associations of maternal and infant metabolomes with immune maturation and allergy development at 12 months in the Swedish NICE-cohort.

Hartvigsson O, Barman M, Rabe H, ..., Brunius C, Sandberg AS

Sci Rep 11 (1) 12706 [2021-06-16; online 2021-06-16]

Impaired Luminal Control of Intestinal Macrophage Maturation in Patients With Ulcerative Colitis During Remission.

Maasfeh L, Härtlova A, Isaksson S, ..., Öhman L, Magnusson MK

Cellular and Molecular Gastroenterology and Hepatology 12 (4) 1415-1432 [2021-06-12; online 2021-06-12]

A Distinct Faecal Microbiota and Metabolite Profile Linked to Bowel Habits in Patients with Irritable Bowel Syndrome.

Ahluwalia B, Iribarren C, Magnusson MK, ..., Simrén M, Öhman L

Cells 10 (6) - [2021-06-10; online 2021-06-10]

The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases.

van der Woude L, Piotrowski M, Klaasse G, ..., Smeekens S, van Zanten M

Plant J. 106 (6) 1523-1540 [2021-06-00; online 2021-05-06]

Chemical Biology Consortium Sweden (CBCS) [Service] Swedish Metabolomics Centre (SMC) [Service]

Loss of Arabidopsis matrix metalloproteinase-5 affects root development and root bacterial communities during drought stress.

Mishra LS, Kim SY, Caddell DF, Coleman-Derr D, Funk C

Physiol Plantarum 172 (2) 1045-1058 [2021-06-00; online 2020-12-16]

Factors Affecting Detoxification of Softwood Enzymatic Hydrolysates Using Sodium Dithionite

Ilanidis D, Stagge S, Alriksson B, Jönsson LJ

Processes 9 (5) 887 [2021-05-18; online 2021-05-18]

Dynamics of Auxin and Cytokinin Metabolism during Early Root and Hypocotyl Growth in Theobroma cacao.

Mboene Noah A, Casanova-Sáez R, Makondy Ango RE, ..., Niemenak N, Ljung K

Plants (Basel) 10 (5) - [2021-05-12; online 2021-05-12]

Stem girdling affects the onset of autumn senescence in aspen in interaction with metabolic signals.

Lihavainen J, Edlund E, Björkén L, ..., Robinson KM, Jansson S

Physiol Plantarum 172 (1) 201-217 [2021-05-00; online 2021-01-07]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Metabolomic profiling reveals plasma GlycA and GlycB as a potential biomarkers for treatment efficiency in rheumatoid arthritis.

Dudka I, Chachaj A, Sebastian A, ..., Gröbner G, Szuba A

Journal of Pharmaceutical and Biomedical Analysis 197 (-) 113971 [2021-04-15; online 2021-02-17]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

Modulation of Arabidopsis root growth by specialized triterpenes.

Bai Y, Fernández-Calvo P, Ritter A, ..., Goossens A, Pollier J

New Phytol. 230 (1) 228-243 [2021-04-00; online 2021-01-19]

Function of the pseudo phosphotransfer proteins has diverged between rice and Arabidopsis.

Vaughan-Hirsch J, Tallerday EJ, Burr CA, ..., Bishopp A, Kieber JJ

Plant J. 106 (1) 159-173 [2021-04-00; online 2021-02-08]

Expanding functional protein sequence spaces using generative adversarial networks

Repecka D, Jauniskis V, Karpus L, ..., Engqvist MKM, Zelezniak A

Nat Mach Intell 3 (4) 324-333 [2021-04-00; online 2021-03-04]

The chemical composition and antioxidant activity of mandaçaia (melipona quadrifasciata) geopropolis varies more due to region than month of collection.

Gabriel MB, Carneiro MJ, de Camargo RCR, Sawaya ACHF

Nat Prod Res - (-) 1-5 [2021-03-10; online 2021-03-10]

A polysaccharide utilization locus from the gut bacterium Dysgonomonas mossii encodes functionally distinct carbohydrate esterases.

Kmezik C, Mazurkewich S, Meents T, ..., Brändén G, Larsbrink J

J. Biol. Chem. 296 (-) 100500 [2021-03-02; online 2021-03-02]

Plasma oxylipin levels associated with preterm birth in preterm labor✰.

Svenvik M, Raffetseder J, Brudin L, ..., Ernerudh J, Nording ML

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 166 (-) 102251 [2021-03-00; online 2021-01-23]

Plasma metabolomics of presymptomatic PSEN1-H163Y mutation carriers: a pilot study.

Natarajan K, Ullgren A, Khoshnood B, ..., Blennow K, Graff C

Ann Clin Transl Neurol 8 (3) 579-591 [2021-03-00; online 2021-01-21]

Bioinformatics Compute and Storage [Service] Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service] Swedish Metabolomics Centre (SMC) [Service]

Overexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees.

Gandla ML, Mähler N, Escamez S, ..., Tuominen H, Jönsson LJ

Biotechnol Biofuels 14 (1) 43 [2021-02-16; online 2021-02-16]

Umbilical cord blood metabolome differs in relation to delivery mode, birth order and sex, maternal diet and possibly future allergy development in rural children.

Ross AB, Barman M, Hartvigsson O, ..., Wold AE, Sandberg AS

PLoS ONE 16 (1) e0242978 [2021-01-25; online 2021-01-25]

Porphyromonas gingivalis Produce Neutrophil Specific Chemoattractants Including Short Chain Fatty Acids.

Dahlstrand Rudin A, Khamzeh A, Venkatakrishnan V, ..., Christenson K, Bylund J

Front. Cell. Infect. Microbiol. 10 (-) 620681 [2021-01-19; online 2021-01-19]

LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes.

Herdenberg C, Mutie PM, Billing O, ..., Franks PW, Hedman H

Commun Biol 4 (1) 90 [2021-01-19; online 2021-01-19]

Sucrose synthase determines carbon allocation in developing wood and alters carbon flow at the whole tree level in aspen.

Dominguez PG, Donev E, Derba-Maceluch M, ..., Mellerowicz EJ, Niittylä T

New Phytol. 229 (1) 186-198 [2021-01-00; online 2020-07-03]

Swedish Metabolomics Centre (SMC) Swedish NMR Centre (SNC) [Collaborative]

Studies of moss reproductive development indicate that auxin biosynthesis in apical stem cells may constitute an ancestral function for focal growth control.

Landberg K, Šimura J, Ljung K, Sundberg E, Thelander M

New Phytol. 229 (2) 845-860 [2021-01-00; online 2020-10-04]

Plasma metabolites associated with exposure to perfluoroalkyl substances and risk of type 2 diabetes - A nested case-control study.

Schillemans T, Shi L, Donat-Vargas C, ..., Åkesson A, Brunius C

Environ Int 146 (-) 106180 [2021-01-00; online 2020-10-25]

Year 2020

Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI).

Chorell E, Olsson T, Jansson JH, Wennberg P

Metabolites 11 (1) 25 [2020-12-31; online 2020-12-31]

The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism.

Reithuber E, Nannapaneni P, Rzhepishevska O, ..., Henriques-Normark B, Mellroth P

MBio 11 (6) e03027-20 [2020-12-15; online 2020-12-15]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Reaction Wood Anatomical Traits and Hormonal Profiles in Poplar Bent Stem and Root.

De Zio E, Montagnoli A, Karady M, ..., Chiatante D, Trupiano D

Front Plant Sci 11 (-) 590985 [2020-12-07; online 2020-12-07]

Differentiation of two Maytenus species and their hybrid via untargeted metabolomics

Antunes ERM, Duarte RS, Moritz T, Sawaya ACHF

Industrial Crops and Products 158 (-) 113014 [2020-12-00; online 2020-12-00]

Changes in lipid and carotenoid metabolism in Chlamydomonas reinhardtii during induction of CO2-concentrating mechanism: Cellular response to low CO2 stress

Abreu IN, Aksmann A, Bajhaiya AK, ..., Selstam E, Moritz T

Algal Research 52 (-) 102099 [2020-12-00; online 2020-12-00]

A metabolite roadmap of the wood-forming tissue in Populus tremula.

Abreu IN, Johansson AI, Sokołowska K, ..., Street NR, Moritz T

New Phytol. 228 (5) 1559-1572 [2020-12-00; online 2020-08-27]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Collaborative]

Identification of Pre-Diagnostic Metabolic Patterns for Glioma Using Subset Analysis of Matched Repeated Time Points.

Jonsson P, Antti H, Späth F, Melin B, Björkblom B

Cancers (Basel) 12 (11) 3349 [2020-11-12; online 2020-11-12]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

The Structure of Riparian Vegetation in Agricultural Landscapes Influences Spider Communities and Aquatic-Terrestrial Linkages

Ramberg E, Burdon FJ, Sargac J, ..., Johnson RK, McKie BG

Water 12 (10) 2855 [2020-10-14; online 2020-10-14]

HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella.

Dong Y, Majda M, Šimura J, ..., Smith RS, Østergaard L

Curr. Biol. 30 (19) 3880-3888.e5 [2020-10-05; online 2020-08-13]

Integration of molecular profiles in a longitudinal wellness profiling cohort.

Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L

Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]

Affinity Proteomics Stockholm [Collaborative] Autoimmunity and Serology Profiling [Collaborative] Bioinformatics Compute and Storage [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Cellular Immunomonitoring [Collaborative] Swedish Metabolomics Centre (SMC) [Collaborative]

Cell-surface receptors enable perception of extracellular cytokinins.

Antoniadi I, Novák O, Gelová Z, ..., Ljung K, Turnbull C

Nat Commun 11 (1) 4284 [2020-08-27; online 2020-08-27]

VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content.

Moessinger C, Nilsson I, Muhl L, ..., Skogsberg J, Eriksson U

EMBO Rep. 21 (7) e49343 [2020-07-03; online 2020-05-24]

Serum Metabolites in Hand-Arm Vibration Exposed Workers.

Vihlborg P, Graff P, Hagenbjörk A, ..., Bryngelsson IL, Eriksson K

J Occup Environ Med 62 (7) 460-465 [2020-07-00; online 2020-07-31]

Auxin export from proximal fruits drives arrest in temporally competent inflorescences.

Ware A, Walker CH, Šimura J, ..., Wilson ZA, Bennett T

NPLANTS 6 (6) 699-707 [2020-06-00; online 2020-05-25]

Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.

Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H

Sci Rep 10 (1) 8343 [2020-05-20; online 2020-05-20]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Comprehensive metabolomics analysis of prostate cancer tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status.

Dudka I, Thysell E, Lundquist K, ..., Wikström P, Gröbner G

BMC Cancer 20 (1) 437 [2020-05-18; online 2020-05-18]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

Lipid accumulation controls the balance between surface connection and scission of caveolae.

Hubert M, Larsson E, Vegesna NVG, ..., Moodie LW, Lundmark R

Elife 9 (-) - [2020-05-04; online 2020-05-04]

Integrated Microscopy Technologies Umeå [Collaborative] Swedish Metabolomics Centre (SMC) [Collaborative]

Plant resistance does not compromise parasitoid-based biocontrol of a strawberry pest.

Weber D, Egan PA, Muola A, Ericson LE, Stenberg JA

Sci Rep 10 (1) 5899 [2020-04-03; online 2020-04-03]

Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity.

Bos MM, Noordam R, Bennett K, ..., Surowiec I, van Heemst D

Metabolomics 16 (3) 35 [2020-03-02; online 2020-03-02]

Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum.

Khoomrung S, Nookaew I, Sen P, ..., Harandi AM, Nielsen J

J. Proteome Res. 19 (1) 269-278 [2020-01-03; online 2019-11-01]

Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma.

Björkblom B, Jonsson P, Tabatabaei P, ..., Bergenheim AT, Antti H

Br. J. Cancer 122 (2) 221-232 [2020-01-00; online 2019-12-10]

Year 2019

Autoregulation of RCO by Low-Affinity Binding Modulates Cytokinin Action and Shapes Leaf Diversity.

Hajheidari M, Wang Y, Bhatia N, ..., Gan X, Tsiantis M

Curr. Biol. 29 (24) 4183-4192.e6 [2019-12-16; online 2019-11-21]

HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion.

van der Woude LC, Perrella G, Snoek BL, ..., Kaiserli E, van Zanten M

Proc. Natl. Acad. Sci. U.S.A. 116 (50) 25343-25354 [2019-12-10; online 2019-11-25]

GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism.

Muthu M, Kumar R, Syed Khaja AS, ..., Persson JL, Nordström A

Cancers (Basel) 11 (12) 1945 [2019-12-05; online 2019-12-05]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS.

Zhu S, Wuolikainen A, Wu J, ..., Forsgren L, Trupp M

J. Mol. Neurosci. 69 (4) 643-657 [2019-12-00; online 2019-11-12]

PECTIN ACETYLESTERASE9 Affects the Transcriptome and Metabolome and Delays Aphid Feeding.

Kloth KJ, Abreu IN, Delhomme N, ..., Moritz T, Albrectsen BR

Plant Physiol. 181 (4) 1704-1720 [2019-12-00; online 2019-09-24]

Bioinformatics Compute and Storage [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial

He X, Parenti M, Grip T, ..., Timby N, Slupsky CM

Sci Rep 9 (1) 339 [2019-12-00; online 2019-01-23]

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Diamanti K, Cavalli M, Pan G, ..., Komorowski J, Wadelius C

Sci Rep 9 (1) 9653 [2019-12-00; online 2019-07-04]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Bergman A, Hellgren J, Moritz T, ..., Nielsen J, Chen Y

Microb. Cell Fact. 18 (1) 25 [2019-12-00; online 2019-02-01]

Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis.

Diab J, Hansen T, Goll R, ..., Florholmen J, Forsdahl G

Metabolites 9 (12) S035-S035 [2019-11-27; online 2019-11-27]

Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3.

Ceballos J, Schwalfenberg M, Karageorgis G, ..., Ziegler S, Waldmann H

Angew. Chem. Int. Ed. Engl. 58 (47) 17016-17025 [2019-11-18; online 2019-10-07]

A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels.

Van Moerkercke A, Duncan O, Zander M, ..., Millar AH, Van Aken O

Proc. Natl. Acad. Sci. U.S.A. 116 (46) 23345-23356 [2019-11-12; online 2019-10-29]

Two-step derivatization for determination of sugar phosphates in plants by combined reversed phase chromatography/tandem mass spectrometry.

Rende U, Niittylä T, Moritz T

Plant Methods 15 (1) 127 [2019-11-07; online 2019-11-07]

A bacterial assay for rapid screening of IAA catabolic enzymes.

Brunoni F, Collani S, Šimura J, ..., Bellini C, Ljung K

Plant Methods 15 (1) 126 [2019-11-04; online 2019-11-04]

Yeast Volatomes Differentially Affect Larval Feeding in an Insect Herbivore.

Ljunggren J, Borrero-Echeverry F, Chakraborty A, ..., Witzgall P, Bengtsson M

Appl. Environ. Microbiol. 85 (21) - [2019-11-01; online 2019-10-16]

PIN-driven auxin transport emerged early in streptophyte evolution.

Skokan R, Medvecká E, Viaene T, ..., Petrášek J, Friml J

NPLANTS 5 (11) 1114-1119 [2019-11-00; online 2019-11-11]

Lipidomics in Ulcerative Colitis Reveal Alteration in Mucosal Lipid Composition Associated With the Disease State.

Diab J, Hansen T, Goll R, ..., Florholmen J, Forsdahl G

Inflamm Bowel Dis 25 (11) 1780-1787 [2019-10-18; online 2019-05-12]

Implantable Organic Electronic Ion Pump Enables ABA Hormone Delivery for Control of Stomata in an Intact Tobacco Plant.

Bernacka-Wojcik I, Huerta M, Tybrandt K, ..., Berggren M, Stavrinidou E

Small 15 (43) e1902189 [2019-10-00; online 2019-09-12]

Leaf metabolic signatures induced by real and simulated herbivory in black mustard (Brassica nigra).

Papazian S, Girdwood T, Wessels BA, ..., Moritz T, Albrectsen BR

Metabolomics 15 (10) 130 [2019-09-28; online 2019-09-28]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Combining microdialysis with metabolomics to characterize the in situ composition of dissolved organic compounds in boreal forest soil

Randewig D, Marshall JD, Näsholm T, Jämtgård S

Soil Biology and Biochemistry 136 (-) 107530 [2019-09-00; online 2019-09-00]

Publisher Correction: Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial.

He X, Parenti M, Grip T, ..., Timby N, Slupsky CM

Sci Rep 9 (1) 12382 [2019-08-22; online 2019-08-22]

Joint and unique multiblock analysis of biological data - multiomics malaria study.

Surowiec I, Skotare T, Sjögren R, ..., Normark J, Trygg J

Faraday Discuss. 218 (0) 268-283 [2019-08-15; online 2019-05-24]

A role for the auxin precursor anthranilic acid in root gravitropism via regulation of PIN-FORMED protein polarity and relocalisation in Arabidopsis.

Doyle SM, Rigal A, Grones P, ..., Novák O, Robert S

New Phytol. 223 (3) 1420-1432 [2019-08-00; online 2019-06-07]

Chemical Biology Consortium Sweden (CBCS) [Service] Swedish Metabolomics Centre (SMC) [Service]

Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1.

Missailidis C, Sørensen N, Ashenafi S, ..., Brighenti S, Bergman P

Nutrients 11 (7) 1675 [2019-07-21; online 2019-07-21]

The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension.

Keskin I, Forsgren E, Lehmann M, ..., Marklund SL, Gilthorpe JD

Acta Neuropathol. 138 (1) 85-101 [2019-07-00; online 2019-03-12]

Alterations in the metabolism of phospholipids, bile acids and branched-chain amino acids predicts development of type 2 diabetes in black South African women: a prospective cohort study.

Zeng Y, Mtintsilana A, Goedecke JH, ..., Olsson T, Chorell E

Metabolism 95 (-) 57-64 [2019-06-00; online 2019-04-04]

Metabolic profiling of zebrafish embryo development from blastula period to early larval stages.

Dhillon SS, Torell F, Donten M, ..., Trygg J, Lundstedt T

PLoS ONE 14 (5) e0213661 [2019-05-14; online 2019-05-14]

Comparisons of analysis of fatty acid methyl ester (FAME) of microalgae by chromatographic techniques

Niemi C, Lage S, Gentili FG

Algal Research 39 (-) 101449 [2019-05-00; online 2019-05-00]

Nitrogen utilization during germination of somatic embryos of Norway spruce: revealing the importance of supplied glutamine for nitrogen metabolism

Carlsson J, Egertsdotter U, Ganeteg U, Svennerstam H

Trees 33 (2) 383-394 [2019-04-00; online 2018-11-09]

Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development.

Vain T, Raggi S, Ferro N, ..., Pauwels L, Robert S

Proc. Natl. Acad. Sci. U.S.A. 116 (13) 6463-6472 [2019-03-26; online 2019-03-08]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers?

Muthu M, Nordström A

Int J Mol Sci 20 (6) 1385 [2019-03-19; online 2019-03-19]

Regulatory Diversification of INDEHISCENT in the Capsella Genus Directs Variation in Fruit Morphology.

Dong Y, Jantzen F, Stacey N, ..., Ljung K, Østergaard L

Curr. Biol. 29 (6) 1038-1046.e4 [2019-03-18; online 2019-02-28]

Surveillance of cell wall diffusion barrier integrity modulates water and solute transport in plants.

Wang P, Calvo-Polanco M, Reyt G, ..., Boursiac Y, Salt DE

Sci Rep 9 (1) 4227 [2019-03-12; online 2019-03-12]

A Quantitative Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Treatment-Naïve and Deep Remission Ulcerative Colitis Patients and the Potential Link With Cytokine Gene Expression.

Diab J, Al-Mahdi R, Gouveia-Figueira S, ..., Florholmen J, Forsdahl G

Inflamm Bowel Dis 25 (3) 490-497 [2019-02-21; online 2018-11-27]

Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease.

Surowiec I, Noordam R, Bennett K, ..., Lundstedt T, van Heemst D

Metabolomics 15 (2) 23 [2019-02-12; online 2019-02-12]

A standardized protocol for comparable analysis of GSH/GSSG by UHPLC-ESI-MSMS for human plasma.

Claeson AS, Gouveia-Figueira S, Stenlund H, Johansson AI

Journal of Chromatography B 1104 (-) 67-72 [2019-01-01; online 2018-11-10]

Tissue-specific hormone profiles from woody poplar roots under bending stress.

De Zio E, Trupiano D, Karady M, ..., Ljung K, Scippa GS

Physiol Plantarum 165 (1) 101-113 [2019-01-00; online 2018-10-15]

Auxin Function in the Brown Alga Dictyota dichotoma.

Bogaert KA, Blommaert L, Ljung K, Beeckman T, De Clerck O

Plant Physiol. 179 (1) 280-299 [2019-01-00; online 2018-11-12]

Year 2018

Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother's Milk Are Strongly Associated with Infant Weight at Four Months of Age-Data from the Odense Child Cohort.

Bruun S, Gouveia-Figueira S, Domellöf M, ..., Fowler CJ, Zachariassen G

Nutrients 10 (11) 1747 [2018-11-13; online 2018-11-13]

The Xerobranching Response Represses Lateral Root Formation When Roots Are Not in Contact with Water.

Orman-Ligeza B, Morris EC, Parizot B, ..., Beeckman T, Draye X

Curr. Biol. 28 (19) 3165-3173.e5 [2018-10-08; online 2018-09-27]

Broad spectrum developmental role of Brachypodium AUX1.

van der Schuren A, Voiniciuc C, Bragg J, ..., Pauly M, Hardtke CS

New Phytol. 219 (4) 1216-1223 [2018-09-00; online 2018-06-27]

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Cedernaes J, Schönke M, Westholm JO, ..., Zierath JR, Benedict C

Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]

Bioinformatics Compute and Storage [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice.

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

J. Proteome Res. 17 (7) 2293-2306 [2018-07-06; online 2018-06-15]

A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial

Otten J, Stomby A, Waling M, ..., Hauksson J, Olsson T

Diabetologia 61 (7) 1548-1559 [2018-07-00; online 2018-04-26]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry.

Kong Z, Jia S, Chabes AL, ..., Moritz T, Chabes A

Nucleic Acids Res. 46 (11) e66 [2018-06-20; online 2018-03-20]

Plant Hormonomics: Multiple Phytohormone Profiling by Targeted Metabolomics

Šimura J, Antoniadi I, Široká J, ..., Ljung K, Novák O

Plant Physiol. 177 (2) 476-489 [2018-06-13; online 2018-04-27]

Circadian clock components control daily growth activities by modulating cytokinin levels and cell division-associated gene expression in Populus trees.

Edwards KD, Takata N, Johansson M, ..., Ljung K, Eriksson ME

Plant Cell Environ. 41 (6) 1468-1482 [2018-06-00; online 2018-04-15]

Assessing Cu impacts on freshwater diatoms: biochemical and metabolomic responses of Tabellaria flocculosa (Roth) Kützing

Gonçalves S, Kahlert M, Almeida SFP, Figueira E

Science of The Total Environment 625 (-) 1234-1246 [2018-06-00; online 2018-06-00]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Darkened Leaves Use Different Metabolic Strategies for Senescence and Survival.

Law SR, Chrobok D, Juvany M, ..., Gardeström P, Keech O

Plant Physiol. 177 (1) 132-150 [2018-05-00; online 2018-03-09]

Ultra-rapid auxin metabolite profiling for high-throughput mutant screening in Arabidopsis.

Pencík A, Casanova-Sáez R, Pilarová V, ..., Ljung K, Novák O

J. Exp. Bot. 69 (10) 2569-2579 [2018-04-27; online 2018-03-08]

Rice auxin influx carrier OsAUX1 facilitates root hair elongation in response to low external phosphate.

Giri J, Bhosale R, Huang G, ..., Swarup R, Bennett MJ

Nat Commun 9 (1) 1408 [2018-04-12; online 2018-04-12]

A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.

Bhosale R, Giri J, Pandey BK, ..., Bennett MJ, Swarup R

Nat Commun 9 (1) 1409 [2018-04-12; online 2018-04-12]

Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

Bergenholm D, Gossing M, Wei Y, Siewers V, Nielsen J

Biotechnol. Bioeng. 115 (4) 932-942 [2018-04-00; online 2018-01-24]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Transcriptional stimulation of rate-limiting components of the autophagic pathway improves plant fitness.

Minina EA, Moschou PN, Vetukuri RR, ..., Hofius D, Bozhkov PV

J. Exp. Bot. 69 (6) 1415-1432 [2018-03-14; online 2018-01-25]

Interferon γ treatment increases endocannabinoid and related N-acylethanolamine levels in T84 human colon carcinoma cells

Alhouayek M, Rankin L, Gouveia-Figueira S, Fowler CJ

British Journal of Pharmacology - (-) - [2018-02-05; online 2018-02-05]

A Common Peptidolytic Mechanism for Targeting Peptide Degradation in Mitochondria and Chloroplasts.

Kmiec B, Branca RMM, Murcha MW, ..., Glaser E, Teixeira PF

Mol Plant 11 (2) 342-345 [2018-02-05; online 2017-11-26]

Clinical Proteomics Mass spectrometry [Service] Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre (SMC) [Service]

Red meat intake in chronic kidney disease patients: Two sides of the coin

Mafra D, Borges NA, Cardozo LFMdF, ..., Lindholm B, Stenvinkel P

Nutrition 46 (-) 26-32 [2018-02-00; online 2018-02-00]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

A multi-omics approach reveals function of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees.

Obudulu O, Mähler N, Skotare T, ..., Trygg J, Tuominen H

BMC Genomics 19 (1) 11 [2018-01-03; online 2018-01-03]

Optimising methods for the recovery and quantification of di- and tripeptides in soil

Jämtgård S, Robinson N, Moritz T, Colgrave ML, Schmidt S

Soil Res. 56 (4) 404 [2018-00-00; online 2018-00-00]

Year 2017

Metabolome and transcriptome profiling reveal new insights into somatic embryo germination in Norway spruce (Picea abies).

Dobrowolska I, Businge E, Abreu IN, Moritz T, Egertsdotter U

Tree Physiol 37 (12) 1752-1766 [2017-12-01; online 2017-10-07]

The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children

Surowiec I, Gouveia-Figueira S, Orikiiriza J, ..., Normark J, Trygg J

Malar. J. 16 (1) - [2017-12-00; online 2017-09-08]

Brassinosteroid signaling-dependent root responses to prolonged elevated ambient temperature

Martins S, Montiel-Jorda A, Cayrel A, ..., Ljung K, Vert G

Nat Commun 8 (1) - [2017-12-00; online 2017-08-21]

Combined transcriptome and translatome analyses reveal a role for tryptophan-dependent auxin biosynthesis in the control of DOG1-dependent seed dormancy

Bai B, Novák O, Ljung K, Hanson J, Bentsink L

New Phytol - (-) - [2017-11-15; online 2017-11-15]

Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1

Yan Z, Liu X, Ljung K, ..., Wang M, Tao Y

Plant Physiol. 175 (3) 1438-1454 [2017-11-00; online 2017-09-20]

Multivariate strategy for the sample selection and integration of multi-batch data in metabolomics

Surowiec I, Johansson E, Torell F, ..., Jakobsson PJ, Trygg J

Metabolomics 13 (10) - [2017-10-00; online 2017-08-24]

Swedish Metabolomics Centre (SMC) [Technology development]

Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells.

Karlsson J, Gouveia-Figueira S, Alhouayek M, Fowler CJ

PLoS ONE 12 (9) e0185011 [2017-09-14; online 2017-09-14]

Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root.

Di Mambro R, De Ruvo M, Pacifici E, ..., Grieneisen VA, Sabatini S

Proc. Natl. Acad. Sci. U.S.A. 114 (36) E7641-E7649 [2017-09-05; online 2017-08-22]

Enhanced Secondary- and Hormone Metabolism in Leaves of Arbuscular Mycorrhizal Medicago truncatula

Adolfsson L, Nziengui H, Abreu IN, ..., Schoefs B, Spetea C

Plant Physiol. 175 (1) 392-411 [2017-09-00; online 2017-07-11]

Nitrogen uptake and assimilation in proliferating embryogenic cultures of Norway spruce-Investigating the specific role of glutamine.

Carlsson J, Svennerstam H, Moritz T, Egertsdotter U, Ganeteg U

PLoS ONE 12 (8) e0181785 [2017-08-24; online 2017-08-24]

Dual herbivore attack and herbivore density affect metabolic profiles of Brassica nigra leaves

Ponzio C, Papazian S, Albrectsen BR, Dicke M, Gols R

Plant, Cell & Environment 40 (8) 1356-1367 [2017-08-00; online 2017-02-24]

Tuning Metabolome Coverage in Reversed Phase LC-MS Metabolomics of MeOH Extracted Samples Using the Reconstitution Solvent Composition.

Lindahl A, Sääf S, Lehtiö J, Nordström A

Anal. Chem. 89 (14) 7356-7364 [2017-07-18; online 2017-06-28]

Clinical Proteomics Mass spectrometry [Service] Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre (SMC) [Technology development]

Establishment of photosynthesis is controlled by two distinct regulatory phases

Dubreuil C, Jin X, Barajas-López JdD, ..., Small ID, Strand A

Plant Physiol. - (-) pp.00435.2017 [2017-06-16; online 2017-06-16]

Cryo-EM [Service] Swedish Metabolomics Centre (SMC) [Service]

The effects of thawing on the plasma metabolome: evaluating differences between thawed plasma and multi-organ samples

Torell F, Bennett K, Rännar S, ..., Lundstedt T, Trygg J

Metabolomics 13 (6) - [2017-06-00; online 2017-04-17]

Metabolite quantification by NMR and LC-MS/MS reveals differences between unstimulated, stimulated, and pure parotid saliva

Figueira J, Gouveia-Figueira S, Öhman C, ..., Nording ML, Öhman A

Journal of Pharmaceutical and Biomedical Analysis 140 (-) 295-300 [2017-06-00; online 2017-06-00]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

Levels of oxylipins, endocannabinoids and related lipids in plasma before and after low-level exposure to acrolein in healthy individuals and individuals with chemical intolerance

Claeson AS, Gouveia-Figueira S, Häggström J, Fowler CJ, Nording ML

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 121 (-) 60-67 [2017-06-00; online 2017-06-00]

Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa

Näsström E, Parry CM, Vu Thieu NT, ..., Antti H, Baker S

Elife 6 (-) - [2017-05-09; online 2017-05-09]

Regulating plant physiology with organic electronics

Poxson DJ, Karady M, Gabrielsson R, ..., Simon DT, Berggren M

Proc Natl Acad Sci USA 114 (18) 4597-4602 [2017-05-02; online 2017-04-18]

Contrasting patterns of cytokinins between years in senescing aspen leaves

Edlund E, Novak O, Karady M, Ljung K, Jansson S

Plant, Cell & Environment 40 (5) 622-634 [2017-05-00; online 2017-03-27]

Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics.

Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A

Metabolomics 13 (5) 61 [2017-04-01; online 2017-04-01]

Clinical Proteomics Mass spectrometry [Service] Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre (SMC) [Service]

The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line

Gabrielsson L, Gouveia-Figueira S, Häggström J, Alhouayek M, Fowler CJ

Pharmacol Res Perspect 5 (2) e00300 [2017-04-00; online 2017-02-27]

Neonatal Cord Blood Oxylipins and Exposure to Particulate Matter in the Early-Life Environment: An ENVIRONAGE Birth Cohort Study.

Martens DS, Gouveia S, Madhloum N, ..., Nording M, Nawrot TS

Environ. Health Perspect. 125 (4) 691-698 [2017-04-00; online 2016-11-05]

Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria

Orikiiriza J, Surowiec I, Lindquist E, ..., Trygg J, Normark J

Metabolomics 13 (4) - [2017-04-00; online 2017-02-23]

Altered expression of maize PLASTOCHRON1 enhances biomass and seed yield by extending cell division duration

Sun X, Cahill J, Van Hautegem T, ..., Inzé D, Nelissen H

Nat Commun 8 (-) 14752 [2017-03-16; online 2017-03-16]

Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease

Falkevall A, Mehlem A, Palombo I, ..., Nash A, Eriksson U

Cell Metabolism 25 (3) 713-726 [2017-03-00; online 2017-03-00]

The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth

Weiste C, Pedrotti L, Selvanayagam J, ..., Hanson J, Dröge-Laser W

PLoS Genet. 13 (2) e1006607 [2017-02-03; online 2017-02-03]

Defense Responses in Aspen with Altered Pectin Methylesterase Activity Reveal the Hormonal Inducers of Tyloses

Leśniewska J, Öhman D, Krzesłowska M, ..., Moritz T, Mellerowicz EJ

Plant Physiol. 173 (2) 1409-1419 [2017-02-00; online 2016-12-06]

cis-Cinnamic Acid Is a Novel, Natural Auxin Efflux Inhibitor That Promotes Lateral Root Formation

Steenackers W, Klíma P, Quareshy M, ..., Boerjan W, Vanholme B

Plant Physiol. 173 (1) 552-565 [2017-01-00; online 2016-11-11]

SHADE AVOIDANCE 4 Is Required for Proper Auxin Distribution in the Hypocotyl

Ge Y, Yan F, Zourelidou M, ..., Schwechheimer C, Tao Y

Plant Physiol. 173 (1) 788-800 [2017-01-00; online 2016-11-21]

A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.

Teixeira PF, Kmiec B, Branca RM, ..., Lehtiö J, Glaser E

Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]

Clinical Proteomics Mass spectrometry [Collaborative] Global Proteomics and Proteogenomics [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Year 2016

Aspen phenylpropanoid genes’ expression levels correlate with genets’ tannin richness and vary both in responses to soil nitrogen and associations with phenolic profiles

Decker VHG, Bandau F, Gundale MJ, Cole CT, Albrectsen BR

Tree Physiol - (-) - [2016-12-15; online 2016-12-15]

Dissecting the Metabolic Role of Mitochondria during Developmental Leaf Senescence.

Chrobok D, Law SR, Brouwer B, ..., Gardeström P, Keech O

Plant Physiol. 172 (4) 2132-2153 [2016-12-00; online 2016-10-21]

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6.

Dobrenel T, Mancera-Martínez E, Forzani C, ..., Hanson J, Meyer C

Front Plant Sci 7 (-) 1611 [2016-11-07; online 2016-11-07]

Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure.

Papazian S, Khaling E, Bonnet C, ..., Blande JD, Albrectsen BR

Plant Physiol. 172 (3) 2057-2078 [2016-11-00; online 2016-10-21]

Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.

Jia M, Andreassen T, Jensen L, ..., Moestue SA, Dahlman-Wright K

Cancer Res. 76 (19) 5634-5646 [2016-10-01; online 2016-07-28]

Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.

Malm L, Tybring G, Moritz T, Landin B, Galli J

Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]

Direct acquisition of organic N by white clover even in the presence of inorganic N

Czaban W, Jämtgård S, Näsholm T, ..., Nicolaisen M, Fomsgaard IS

Plant Soil 407 (1-2) 91-107 [2016-10-00; online 2016-04-15]

Loss of ncm(5) and mcm(5) wobble uridine side chains results in an altered metabolic profile.

Karlsborn T, Mahmud AK, Tükenmez H, Byström AS

Metabolomics 12 (12) 177 [2016-09-27; online 2016-09-27]

Dioxygenase-encoding AtDAO1 gene controls IAA oxidation and homeostasis in Arabidopsis.

Porco S, Pěnčík A, Rashed A, ..., Bennett MJ, Ljung K

Proc. Natl. Acad. Sci. U.S.A. 113 (39) 11016-11021 [2016-09-27; online 2016-09-22]

Overlap in serum metabolic profiles between non-related diseases: Implications for LC-MS metabolomics biomarker discovery.

Lindahl A, Forshed J, Nordström A

Biochem. Biophys. Res. Commun. 478 (3) 1472-1477 [2016-09-23; online 2016-08-28]

Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis.

Bengtsson AA, Trygg J, Wuttge DM, ..., Rännar S, Lundstedt T

PLoS ONE 11 (7) e0159384 [2016-07-21; online 2016-07-21]

The Effects of High Steady State Auxin Levels on Root Cell Elongation in Brachypodium.

Pacheco-Villalobos D, Díaz-Moreno SM, van der Schuren A, ..., Bulone V, Hardtke CS

Plant Cell - (-) - [2016-05-05; online 2016-05-05]

Reduced mitochondrial malate dehydrogenase activity has a strong effect on photorespiratory metabolism as revealed by 13C labelling.

Lindén P, Keech O, Stenlund H, Gardeström P, Moritz T

J. Exp. Bot. 67 (10) 3123-3135 [2016-05-00; online 2016-02-19]

Metabolomics study of fatigue in patients with rheumatoid arthritis naïve to biological treatment.

Surowiec I, Gjesdal CG, Jonsson G, ..., Trygg J, Omdal R

Rheumatol. Int. 36 (5) 703-711 [2016-05-00; online 2016-01-25]

TOR Signaling and Nutrient Sensing.

Dobrenel T, Caldana C, Hanson J, ..., Veit B, Meyer C

Annu Rev Plant Biol 67 (-) 261-285 [2016-04-29; online 2016-02-26]

PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B.

Mehlem A, Palombo I, Wang X, ..., Eriksson U, Falkevall A

Diabetes 65 (4) 861-873 [2016-04-00; online 2016-01-30]

Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects.

Wuolikainen A, Jonsson P, Ahnlund M, ..., Andersen PM, Trupp M

Mol Biosyst 12 (4) 1287-1298 [2016-04-00; online 2016-02-18]

Local auxin metabolism regulates environment-induced hypocotyl elongation

Zheng Z, Guo Y, Novák O, ..., Noel JP, Chory J

NPLANTS 2 (4) 16025 [2016-03-21; online 2016-03-21]

Rat Prostate Tumor Cells Progress in the Bone Microenvironment to a Highly Aggressive Phenotype.

Bergström SH, Rudolfsson SH, Bergh A

Neoplasia 18 (3) 152-161 [2016-03-00; online 2016-03-20]

Quantitative Auxin Metabolite Profiling Using Stable Isotope Dilution UHPLC-MS/MS.

Novák O, Pěnčík A, Blahoušek O, Ljung K

Curr Protoc Plant Biol 1 (2) 419-430 [2016-03-00; online 2016-03-01]

Quantitative proteomics reveals protein profiles underlying major transitions in aspen wood development.

Obudulu O, Bygdell J, Sundberg B, ..., Trygg J, Wingsle G

BMC Genomics 17 (-) 119 [2016-02-18; online 2016-02-18]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Postprandial metabolomics: A pilot mass spectrometry and NMR study of the human plasma metabolome in response to a challenge meal.

Karimpour M, Surowiec I, Wu J, ..., Zivkovic AM, Nording ML

Anal. Chim. Acta 908 (-) 121-131 [2016-02-18; online 2016-01-31]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Tissue sample stability: thawing effect on multi-organ samples

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

Metabolomics 12 (2) - [2016-02-00; online 2015-12-31]

Metabolites in Blood for Prediction of Bacteremic Sepsis in the Emergency Room.

Kauppi AM, Edin A, Ziegler I, ..., Strålin K, Johansson A

PLoS ONE 11 (1) e0147670 [2016-01-22; online 2016-01-22]

Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light.

Pedmale UV, Huang SS, Zander M, ..., Ecker JR, Chory J

Cell 164 (1-2) 233-245 [2016-01-14; online 2016-01-05]

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.

Missailidis C, Hällqvist J, Qureshi AR, ..., Stenvinkel P, Bergman P

PLoS ONE 11 (1) e0141738 [2016-01-11; online 2016-01-11]

Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions.

Wu J, Gouveia-Figueira S, Domellöf M, Zivkovic AM, Nording ML

Prostaglandins Other Lipid Mediat. 122 (-) 28-36 [2016-01-00; online 2015-12-15]

Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.

Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A

Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-23]

Year 2013

Plasma and erythrocyte glutathione peroxidase activity, serum selenium concentration, and plasma total antioxidant capacity in cats with IRIS stages I-IV chronic kidney disease.

Krofič Žel M, Tozon N, Nemec Svete A

J. Vet. Intern. Med. 28 (1) 130-136 [2013-12-16; online 2013-12-16]