Swedish Metabolomics Centre (SMC)

A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial

Otten J, Stomby A, Waling M, ..., Hauksson J, Olsson T

Diabetologia 61 (7) 1548-1559 [2018-07-00; online 2018-04-26]

Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

Kong Z, Jia S, Chabes AL, ..., Moritz T, Chabes A

Nucleic Acids Res 46 (11) e66-e66 [2018-06-20; online 2018-03-15]

Assessing Cu impacts on freshwater diatoms: biochemical and metabolomic responses of Tabellaria flocculosa (Roth) Kützing

Gonçalves S, Kahlert M, Almeida SFP, Figueira E

Science of The Total Environment 625 (-) 1234-1246 [2018-06-00; online 2018-06-00]

Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

Bergenholm D, Gossing M, Wei Y, Siewers V, Nielsen J

Biotechnol. Bioeng. 115 (4) 932-942 [2018-04-00; online 2018-01-24]

Interferon γ treatment increases endocannabinoid and related N -acylethanolamine levels in T84 human colon carcinoma cells

Alhouayek M, Rankin L, Gouveia-Figueira S, Fowler CJ

British Journal of Pharmacology - (-) - [2018-02-05; online 2018-02-05]

Red meat intake in chronic kidney disease patients: Two sides of the coin

Mafra D, Borges NA, Cardozo LFMdF, ..., Lindholm B, Stenvinkel P

Nutrition 46 (-) 26-32 [2018-02-00; online 2018-02-00]

A Common Peptidolytic Mechanism for Targeting Peptide Degradation in Mitochondria and Chloroplasts

Kmiec B, Branca RMM, Murcha MW, ..., Glaser E, Teixeira PF

Molecular Plant 11 (2) 342-345 [2018-02-00; online 2018-02-00]

Optimising methods for the recovery and quantification of di- and tripeptides in soil

J�mtg�rd S, Robinson N, Moritz T, Colgrave ML, Schmidt S

Soil Res. - (-) - [2018-00-00; online 2018-00-00]

Year 2017

Metabolome and transcriptome profiling reveal new insights into somatic embryo germination in Norway spruce (Picea abies)

Dobrowolska I, Businge E, Abreu IN, Moritz T, Egertsdotter U

Tree Physiol 37 (12) 1752-1766 [2017-12-01; online 2017-06-28]

Brassinosteroid signaling-dependent root responses to prolonged elevated ambient temperature

Martins S, Montiel-Jorda A, Cayrel A, ..., Ljung K, Vert G

Nat Commun 8 (1) - [2017-12-00; online 2017-08-21]

The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children

Surowiec I, Gouveia-Figueira S, Orikiiriza J, ..., Normark J, Trygg J

Malar. J. 16 (1) - [2017-12-00; online 2017-09-08]

Combined transcriptome and translatome analyses reveal a role for tryptophan-dependent auxin biosynthesis in the control of DOG1-dependent seed dormancy

Bai B, Novák O, Ljung K, Hanson J, Bentsink L

New Phytol - (-) - [2017-11-15; online 2017-11-15]

Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1

Yan Z, Liu X, Ljung K, ..., Wang M, Tao Y

Plant Physiol. 175 (3) 1438-1454 [2017-11-00; online 2017-09-20]

Multivariate strategy for the sample selection and integration of multi-batch data in metabolomics

Surowiec I, Johansson E, Torell F, ..., Jakobsson PJ, Trygg J

Metabolomics 13 (10) - [2017-10-00; online 2017-08-24]

Swedish Metabolomics Centre (SMC) [Technology development]

Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells

Karlsson J, Gouveia-Figueira S, Alhouayek M, Fowler CJ

PLoS ONE 12 (9) e0185011 [2017-09-14; online 2017-09-14]

Auxin minimum triggers the developmental switch from cell division to cell differentiation in theArabidopsisroot

Di Mambro R, De Ruvo M, Pacifici E, ..., Grieneisen VA, Sabatini S

Proc Natl Acad Sci USA 114 (36) E7641-E7649 [2017-09-05; online 2017-08-22]

Enhanced Secondary- and Hormone Metabolism in Leaves of Arbuscular Mycorrhizal Medicago truncatula

Adolfsson L, Nziengui H, Abreu IN, ..., Schoefs B, Spetea C

Plant Physiol. 175 (1) 392-411 [2017-09-00; online 2017-07-11]

Nitrogen uptake and assimilation in proliferating embryogenic cultures of Norway spruce—Investigating the specific role of glutamine

Carlsson J, Svennerstam H, Moritz T, Egertsdotter U, Ganeteg U

PLoS ONE 12 (8) e0181785 [2017-08-24; online 2017-08-24]

Dual herbivore attack and herbivore density affect metabolic profiles of Brassica nigra leaves

Ponzio C, Papazian S, Albrectsen BR, Dicke M, Gols R

Plant, Cell & Environment 40 (8) 1356-1367 [2017-08-00; online 2017-02-24]

Tuning Metabolome Coverage in Reversed Phase LC–MS Metabolomics of MeOH Extracted Samples Using the Reconstitution Solvent Composition

Lindahl A, Sääf S, Lehtiö J, Nordström A

Anal. Chem. 89 (14) 7356-7364 [2017-07-18; online 2017-06-28]

Chemical Proteomics & Proteogenomics [Service] Clinical Proteomics Mass spectrometry [Service] Swedish Metabolomics Centre (SMC) [Technology development]

Establishment of photosynthesis is controlled by two distinct regulatory phases

Dubreuil C, Jin X, Barajas-López JdD, ..., Small ID, Strand A

Plant Physiol. - (-) pp.00435.2017 [2017-06-16; online 2017-06-16]

Levels of oxylipins, endocannabinoids and related lipids in plasma before and after low-level exposure to acrolein in healthy individuals and individuals with chemical intolerance

Claeson AS, Gouveia-Figueira S, Häggström J, Fowler CJ, Nording ML

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 121 (-) 60-67 [2017-06-00; online 2017-06-00]

The effects of thawing on the plasma metabolome: evaluating differences between thawed plasma and multi-organ samples

Torell F, Bennett K, Rännar S, ..., Lundstedt T, Trygg J

Metabolomics 13 (6) - [2017-06-00; online 2017-04-17]

Metabolite quantification by NMR and LC-MS/MS reveals differences between unstimulated, stimulated, and pure parotid saliva

Figueira J, Gouveia-Figueira S, Öhman C, ..., Nording ML, Öhman A

Journal of Pharmaceutical and Biomedical Analysis 140 (-) 295-300 [2017-06-00; online 2017-06-00]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa

Näsström E, Parry CM, Vu Thieu NT, ..., Antti H, Baker S

Elife 6 (-) - [2017-05-09; online 2017-05-09]

Regulating plant physiology with organic electronics

Poxson DJ, Karady M, Gabrielsson R, ..., Simon DT, Berggren M

Proc Natl Acad Sci USA 114 (18) 4597-4602 [2017-05-02; online 2017-04-18]

Contrasting patterns of cytokinins between years in senescing aspen leaves

Edlund E, Novak O, Karady M, Ljung K, Jansson S

Plant, Cell & Environment 40 (5) 622-634 [2017-05-00; online 2017-03-27]

Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics

Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A

Metabolomics 13 (5) - [2017-05-00; online 2017-04-01]

Chemical Proteomics & Proteogenomics [Service] Clinical Proteomics Mass spectrometry [Service] Swedish Metabolomics Centre (SMC) [Service]

Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria

Orikiiriza J, Surowiec I, Lindquist E, ..., Trygg J, Normark J

Metabolomics 13 (4) - [2017-04-00; online 2017-02-23]

Neonatal Cord Blood Oxylipins and Exposure to Particulate Matter in the Early-Life Environment: An ENVIRONAGE Birth Cohort Study.

Martens DS, Gouveia S, Madhloum N, ..., Nording M, Nawrot TS

pmc

Environ. Health Perspect. 125 (4) 691-698 [2017-04-00; online 2016-11-05]

The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line

Gabrielsson L, Gouveia-Figueira S, Häggström J, Alhouayek M, Fowler CJ

Pharmacol Res Perspect 5 (2) e00300 [2017-04-00; online 2017-02-27]

Altered expression of maize PLASTOCHRON1 enhances biomass and seed yield by extending cell division duration

Sun X, Cahill J, Van Hautegem T, ..., Inzé D, Nelissen H

Nat Commun 8 (-) 14752 [2017-03-16; online 2017-03-16]

Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease

Falkevall A, Mehlem A, Palombo I, ..., Nash A, Eriksson U

Cell Metabolism 25 (3) 713-726 [2017-03-00; online 2017-03-00]

The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth

Weiste C, Pedrotti L, Selvanayagam J, ..., Hanson J, Dröge-Laser W

PLoS Genet. 13 (2) e1006607 [2017-02-03; online 2017-02-03]

Defense Responses in Aspen with Altered Pectin Methylesterase Activity Reveal the Hormonal Inducers of Tyloses

Leśniewska J, Öhman D, Krzesłowska M, ..., Moritz T, Mellerowicz EJ

Plant Physiol. 173 (2) 1409-1419 [2017-02-00; online 2016-12-06]

cis-Cinnamic Acid Is a Novel, Natural Auxin Efflux Inhibitor That Promotes Lateral Root Formation

Steenackers W, Klíma P, Quareshy M, ..., Boerjan W, Vanholme B

Plant Physiol. 173 (1) 552-565 [2017-01-00; online 2016-11-11]

A multi-step peptidolytic cascade for amino acid recovery in chloroplasts

Teixeira PF, Kmiec B, Branca RMM, ..., Lehtiö J, Glaser E

Nat Chem Biol 13 (1) 15-17 [2017-01-00; online 2016-10-31]

Chemical Proteomics & Proteogenomics [Collaborative] Clinical Proteomics Mass spectrometry [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

SHADE AVOIDANCE 4 Is Required for Proper Auxin Distribution in the Hypocotyl

Ge Y, Yan F, Zourelidou M, ..., Schwechheimer C, Tao Y

Plant Physiol. 173 (1) 788-800 [2017-01-00; online 2016-11-21]

Year 2016

Aspen phenylpropanoid genes’ expression levels correlate with genets’ tannin richness and vary both in responses to soil nitrogen and associations with phenolic profiles

Decker VHG, Bandau F, Gundale MJ, Cole CT, Albrectsen BR

Tree Physiol - (-) - [2016-12-15; online 2016-12-15]

Dissecting the Metabolic Role of Mitochondria during Developmental Leaf Senescence.

Chrobok D, Law SR, Brouwer B, ..., Gardeström P, Keech O

pmc

Plant Physiol. 172 (4) 2132-2153 [2016-12-00; online 2016-10-21]

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6.

Dobrenel T, Mancera-Martínez E, Forzani C, ..., Hanson J, Meyer C

pmc

Front Plant Sci 7 (-) 1611 [2016-11-07; online 2016-11-07]

Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure.

Papazian S, Khaling E, Bonnet C, ..., Blande JD, Albrectsen BR

pmc

Plant Physiol. 172 (3) 2057-2078 [2016-11-00; online 2016-10-21]

Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.

Jia M, Andreassen T, Jensen L, ..., Moestue SA, Dahlman-Wright K

Cancer Res. 76 (19) 5634-5646 [2016-10-01; online 2016-07-28]

Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.

Malm L, Tybring G, Moritz T, Landin B, Galli J

Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]

Direct acquisition of organic N by white clover even in the presence of inorganic N

Czaban W, Jämtgård S, Näsholm T, ..., Nicolaisen M, Fomsgaard IS

Plant Soil 407 (1-2) 91-107 [2016-10-00; online 2016-04-15]

Dioxygenase-encoding AtDAO1 gene controls IAA oxidation and homeostasis in Arabidopsis.

Porco S, Pěnčík A, Rashed A, ..., Bennett MJ, Ljung K

pmc

Proc. Natl. Acad. Sci. U.S.A. 113 (39) 11016-11021 [2016-09-27; online 2016-09-22]

Loss of ncm(5) and mcm(5) wobble uridine side chains results in an altered metabolic profile.

Karlsborn T, Mahmud AK, Tükenmez H, Byström AS

pmc

Metabolomics 12 (12) 177 [2016-09-27; online 2016-09-27]

Overlap in serum metabolic profiles between non-related diseases: Implications for LC-MS metabolomics biomarker discovery.

Lindahl A, Forshed J, Nordström A

Biochem. Biophys. Res. Commun. 478 (3) 1472-1477 [2016-09-23; online 2016-09-02]

Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis.

Bengtsson AA, Trygg J, Wuttge DM, ..., Rännar S, Lundstedt T

pmc

PLoS ONE 11 (7) e0159384 [2016-07-21; online 2016-07-21]

Quantitative Auxin Metabolite Profiling Using Stable Isotope Dilution UHPLC-MS/MS

Novák O, Pěnčík A, Blahoušek O, Ljung K

Curr Protoc Plant Biol - (-) 419-430 [2016-06-10; online 2016-06-10]

The Effects of High Steady State Auxin Levels on Root Cell Elongation in Brachypodium.

Pacheco-Villalobos D, Díaz-Moreno SM, van der Schuren A, ..., Bulone V, Hardtke CS

Plant Cell - (-) - [2016-05-05; online 2016-05-05]

Metabolomics study of fatigue in patients with rheumatoid arthritis naïve to biological treatment.

Surowiec I, Gjesdal CG, Jonsson G, ..., Trygg J, Omdal R

Rheumatol. Int. 36 (5) 703-711 [2016-05-00; online 2016-01-25]

Reduced mitochondrial malate dehydrogenase activity has a strong effect on photorespiratory metabolism as revealed by 13C labelling.

Lindén P, Keech O, Stenlund H, Gardeström P, Moritz T

pmc

J. Exp. Bot. 67 (10) 3123-3135 [2016-05-00; online 2016-02-19]

TOR Signaling and Nutrient Sensing.

Dobrenel T, Caldana C, Hanson J, ..., Veit B, Meyer C

Annu Rev Plant Biol 67 (-) 261-285 [2016-04-29; online 2016-02-26]

PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B.

Mehlem A, Palombo I, Wang X, ..., Eriksson U, Falkevall A

Diabetes 65 (4) 861-873 [2016-04-00; online 2016-01-30]

Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects.

Wuolikainen A, Jonsson P, Ahnlund M, ..., Andersen PM, Trupp M

Mol Biosyst 12 (4) 1287-1298 [2016-04-00; online 2016-02-18]

Local auxin metabolism regulates environment-induced hypocotyl elongation

Zheng Z, Guo Y, Novák O, ..., Noel JP, Chory J

NPLANTS 2 (4) 16025 [2016-03-21; online 2016-03-21]

Rat Prostate Tumor Cells Progress in the Bone Microenvironment to a Highly Aggressive Phenotype.

Bergström SH, Rudolfsson SH, Bergh A

pmc

Neoplasia 18 (3) 152-161 [2016-03-00; online 2016-03-20]

Postprandial metabolomics: A pilot mass spectrometry and NMR study of the human plasma metabolome in response to a challenge meal.

Karimpour M, Surowiec I, Wu J, ..., Zivkovic AM, Nording ML

Anal. Chim. Acta 908 (-) 121-131 [2016-02-18; online 2016-01-31]

Bioinformatics Support and Infrastructure [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Quantitative proteomics reveals protein profiles underlying major transitions in aspen wood development.

Obudulu O, Bygdell J, Sundberg B, ..., Trygg J, Wingsle G

pmc

BMC Genomics 17 (-) 119 [2016-02-18; online 2016-02-18]

Bioinformatics Support and Infrastructure [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Tissue sample stability: thawing effect on multi-organ samples

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

Metabolomics 12 (2) - [2016-02-00; online 2015-12-31]

Metabolites in Blood for Prediction of Bacteremic Sepsis in the Emergency Room.

Kauppi AM, Edin A, Ziegler I, ..., Strålin K, Johansson A

pmc

PLoS ONE 11 (1) e0147670 [2016-01-22; online 2016-01-22]

Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light.

Pedmale UV, Huang SS, Zander M, ..., Ecker JR, Chory J

pmc mid

Cell 164 (1-2) 233-245 [2016-01-14; online 2016-01-05]

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.

Missailidis C, Hällqvist J, Qureshi AR, ..., Stenvinkel P, Bergman P

pmc

PLoS ONE 11 (1) e0141738 [2016-01-11; online 2016-01-11]

Swedish Metabolomics Centre (SMC) [Collaborative]

Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions.

Wu J, Gouveia-Figueira S, Domellöf M, Zivkovic AM, Nording ML

Prostaglandins Other Lipid Mediat. 122 (-) 28-36 [2016-01-00; online 2015-12-15]

Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.

Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A

pmc

Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-25]

Year 2013

Plasma and erythrocyte glutathione peroxidase activity, serum selenium concentration, and plasma total antioxidant capacity in cats with IRIS stages I-IV chronic kidney disease.

Krofič Žel M, Tozon N, Nemec Svete A

pmc

J. Vet. Intern. Med. 28 (1) 130-136 [2013-12-16; online 2013-12-16]