Swedish Metabolomics Centre (SMC)

Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI)

Chorell E, Olsson T, Jansson JH, Wennberg P

Metabolites 11 (1) 25 [2020-12-31; online 2020-12-31]

Stem Girdling Affects The Onset of Autumn Senescence In Aspen In Interaction With Metabolic Signals

Lihavainen J, Edlund E, Björkén L, ..., Robinson KM, Jansson S

Physiol Plantarum - (-) - [2020-12-25; online 2020-12-25]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism

Reithuber E, Nannapaneni P, Rzhepishevska O, ..., Henriques-Normark B, Mellroth P

MBio 11 (6) e03027-20 [2020-12-22; online 2020-12-15]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Loss of Arabidopsis matrix metalloproteinase‐5 affects root development and root bacterial communities during drought stress

Mishra LS, Kim S, Caddell DF, Coleman‐Derr D, Funk C

Physiol Plantarum - (-) - [2020-12-16; online 2020-12-16]

Reaction Wood Anatomical Traits and Hormonal Profiles in Poplar Bent Stem and Root

De Zio E, Montagnoli A, Karady M, ..., Chiatante D, Trupiano D

Front Plant Sci 11 (-) - [2020-12-07; online 2020-12-07]

Comprehensive metabolomics analysis of prostate cancer tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status

Dudka I, Thysell E, Lundquist K, ..., Wikström P, Gröbner G

BMC Cancer 20 (1) - [2020-12-00; online 2020-05-18]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

Differentiation of two Maytenus species and their hybrid via untargeted metabolomics

Antunes ERM, Duarte RS, Moritz T, Sawaya ACHF

Industrial Crops and Products 158 (-) 113014 [2020-12-00; online 2020-12-00]

Plant resistance does not compromise parasitoid-based biocontrol of a strawberry pest

Weber D, Egan PA, Muola A, Ericson LE, Stenberg JA

Sci Rep 10 (1) - [2020-12-00; online 2020-04-03]

Changes in lipid and carotenoid metabolism in Chlamydomonas reinhardtii during induction of CO2-concentrating mechanism: Cellular response to low CO2 stress

Abreu IN, Aksmann A, Bajhaiya AK, ..., Selstam E, Moritz T

Algal Research 52 (-) 102099 [2020-12-00; online 2020-12-00]

Swedish Metabolomics Centre (SMC)

Cell-surface receptors enable perception of extracellular cytokinins

Antoniadi I, Novák O, Gelová Z, ..., Ljung K, Turnbull C

Nat Commun 11 (1) - [2020-12-00; online 2020-08-27]

Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes

Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H

Sci Rep 10 (1) - [2020-12-00; online 2020-05-20]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

A metabolite roadmap of the wood‐forming tissue in Populus tremula

Abreu IN, Johansson AI, Sokołowska K, ..., Street NR, Moritz T

New Phytol 228 (5) 1559-1572 [2020-12-00; online 2020-08-27]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Collaborative]

Identification of Pre-Diagnostic Metabolic Patterns for Glioma Using Subset Analysis of Matched Repeated Time Points

Jonsson P, Antti H, Späth F, Melin B, Björkblom B

Cancers (Basel) 12 (11) 3349 [2020-11-12; online 2020-11-12]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

The Structure of Riparian Vegetation in Agricultural Landscapes Influences Spider Communities and Aquatic-Terrestrial Linkages

Ramberg E, Burdon FJ, Sargac J, ..., Johnson RK, McKie BG

Water 12 (10) 2855 [2020-10-14; online 2020-10-14]

HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella

Dong Y, Majda M, Šimura J, ..., Smith RS, Østergaard L

Current Biology 30 (19) 3880-3888.e5 [2020-10-00; online 2020-10-00]

Swedish Metabolomics Centre (SMC)

Integration of molecular profiles in a longitudinal wellness profiling cohort.

Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L

pii: 10.1038/s41467-020-18148-7

Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]

Autoimmunity Profiling [Collaborative] Bioinformatics Compute and Storage [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Mass Cytometry [Collaborative] Swedish Metabolomics Centre (SMC) [Collaborative] Translational Plasma Profiling [Collaborative]

VEGF‐B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content

Moessinger C, Nilsson I, Muhl L, ..., Skogsberg J, Eriksson U

EMBO rep 21 (7) - [2020-07-03; online 2020-05-24]

Serum Metabolites in Hand-Arm Vibration Exposed Workers

Vihlborg P, Graff P, Hagenbjörk A, ..., Bryngelsson IL, Eriksson K

- 62 (7) 460-465 [2020-07-00; online 2020-04-06]

Auxin export from proximal fruits drives arrest in temporally competent inflorescences

Ware A, Walker CH, Šimura J, ..., Wilson ZA, Bennett T

NPLANTS 6 (6) 699-707 [2020-06-00; online 2020-05-25]

Lipid accumulation controls the balance between surface connection and scission of caveolae

Hubert M, Larsson E, Vegesna NVG, ..., Moodie LW, Lundmark R

Elife 9 (-) - [2020-05-04; online 2020-05-04]

Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity

Bos MM, Noordam R, Bennett K, ..., Surowiec I, van Heemst D

Metabolomics 16 (3) - [2020-03-00; online 2020-03-02]

Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum

Khoomrung S, Nookaew I, Sen P, ..., Harandi AM, Nielsen J

J. Proteome Res. 19 (1) 269-278 [2020-01-03; online 2019-10-18]

Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma

Björkblom B, Jonsson P, Tabatabaei P, ..., Bergenheim AT, Antti H

Br J Cancer 122 (2) 221-232 [2020-01-00; online 2019-12-10]

Year 2019

HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion

van der Woude LC, Perrella G, Snoek BL, ..., Kaiserli E, van Zanten M

Proc Natl Acad Sci USA 116 (50) 25343-25354 [2019-12-10; online 2019-11-25]

GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism

Muthu M, Kumar R, Syed Khaja AS, ..., Persson JL, Nordström A

Cancers (Basel) 11 (12) 1945 [2019-12-05; online 2019-12-05]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial

He X, Parenti M, Grip T, ..., Timby N, Slupsky CM

Sci Rep 9 (1) - [2019-12-00; online 2019-01-23]

Surveillance of cell wall diffusion barrier integrity modulates water and solute transport in plants

Wang P, Calvo-Polanco M, Reyt G, ..., Boursiac Y, Salt DE

Sci Rep 9 (1) - [2019-12-00; online 2019-03-12]

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Bergman A, Hellgren J, Moritz T, ..., Nielsen J, Chen Y

Microb. Cell Fact. 18 (1) - [2019-12-00; online 2019-02-01]

A bacterial assay for rapid screening of IAA catabolic enzymes

Brunoni F, Collani S, Šimura J, ..., Bellini C, Ljung K

Plant Methods 15 (1) - [2019-12-00; online 2019-11-04]

Publisher Correction: Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial

He X, Parenti M, Grip T, ..., Timby N, Slupsky CM

Sci Rep 9 (1) - [2019-12-00; online 2019-08-22]

Two-step derivatization for determination of sugar phosphates in plants by combined reversed phase chromatography/tandem mass spectrometry

Rende U, Niittylä T, Moritz T

Plant Methods 15 (1) - [2019-12-00; online 2019-11-07]

Autoregulation of RCO by Low-Affinity Binding Modulates Cytokinin Action and Shapes Leaf Diversity

Hajheidari M, Wang Y, Bhatia N, ..., Gan X, Tsiantis M

Current Biology 29 (24) 4183-4192.e6 [2019-12-00; online 2019-12-00]

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Diamanti K, Cavalli M, Pan G, ..., Komorowski J, Wadelius C

Sci Rep 9 (1) - [2019-12-00; online 2019-07-04]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

PECTIN ACETYLESTERASE9 Affects the Transcriptome and Metabolome and Delays Aphid Feeding

Kloth KJ, Abreu IN, Delhomme N, ..., Moritz T, Albrectsen BR

Plant Physiol. 181 (4) 1704-1720 [2019-12-00; online 2019-09-24]

Bioinformatics Compute and Storage [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS

Zhu S, Wuolikainen A, Wu J, ..., Forsgren L, Trupp M

J Mol Neurosci 69 (4) 643-657 [2019-12-00; online 2019-11-12]

Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3

Ceballos J, Schwalfenberg M, Karageorgis G, ..., Ziegler S, Waldmann H

Angew. Chem. Int. Ed. 58 (47) 17016-17025 [2019-11-18; online 2019-10-07]

A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels

Van Moerkercke A, Duncan O, Zander M, ..., Millar AH, Van Aken O

Proc Natl Acad Sci USA 116 (46) 23345-23356 [2019-11-12; online 2019-10-29]

PIN-driven auxin transport emerged early in streptophyte evolution

Skokan R, Medvecká E, Viaene T, ..., Petrášek J, Friml J

NPLANTS 5 (11) 1114-1119 [2019-11-00; online 2019-11-11]

Lipidomics in Ulcerative Colitis Reveal Alteration in Mucosal Lipid Composition Associated With the Disease State

Diab J, Hansen T, Goll R, ..., Florholmen J, Forsdahl G

- 25 (11) 1780-1787 [2019-10-18; online 2019-05-11]

Implantable Organic Electronic Ion Pump Enables ABA Hormone Delivery for Control of Stomata in an Intact Tobacco Plant

Bernacka‐Wojcik I, Huerta M, Tybrandt K, ..., Berggren M, Stavrinidou E

Small 15 (43) 1902189 [2019-10-00; online 2019-09-12]

Leaf metabolic signatures induced by real and simulated herbivory in black mustard (Brassica nigra)

Papazian S, Girdwood T, Wessels BA, ..., Moritz T, Albrectsen BR

Metabolomics 15 (10) - [2019-10-00; online 2019-09-28]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Combining microdialysis with metabolomics to characterize the in situ composition of dissolved organic compounds in boreal forest soil

Randewig D, Marshall JD, Näsholm T, Jämtgård S

Soil Biology and Biochemistry 136 (-) 107530 [2019-09-00; online 2019-09-00]

Yeast Volatomes Differentially Affect Larval Feeding in an Insect Herbivore

Ljunggren J, Borrero-Echeverry F, Chakraborty A, ..., Witzgall P, Bengtsson M

Appl Environ Microbiol 85 (21) - [2019-08-23; online 2019-10-16]

A role for the auxin precursor anthranilic acid in root gravitropism via regulation of PIN-FORMED protein polarity and relocalisation in Arabidopsis

Doyle SM, Rigal A, Grones P, ..., Novák O, Robert S

New Phytol 223 (3) 1420-1432 [2019-08-00; online 2019-06-07]

Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1

Missailidis C, Sørensen N, Ashenafi S, ..., Brighenti S, Bergman P

Nutrients 11 (7) 1675 [2019-07-21; online 2019-07-21]

The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension

Keskin I, Forsgren E, Lehmann M, ..., Marklund SL, Gilthorpe JD

Acta Neuropathol 138 (1) 85-101 [2019-07-00; online 2019-03-12]

Alterations in the metabolism of phospholipids, bile acids and branched-chain amino acids predicts development of type 2 diabetes in black South African women: a prospective cohort study

Zeng Y, Mtintsilana A, Goedecke JH, ..., Olsson T, Chorell E

Metabolism 95 (-) 57-64 [2019-06-00; online 2019-06-00]

Metabolic profiling of zebrafish embryo development from blastula period to early larval stages

Dhillon SS, Torell F, Donten M, ..., Trygg J, Lundstedt T

PLoS ONE 14 (5) e0213661 [2019-05-14; online 2019-05-14]

Comparisons of analysis of fatty acid methyl ester (FAME) of microalgae by chromatographic techniques

Niemi C, Lage S, Gentili FG

Algal Research 39 (-) 101449 [2019-05-00; online 2019-05-00]

Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development

Vain T, Raggi S, Ferro N, ..., Pauwels L, Robert S

Proc Natl Acad Sci USA 116 (13) 6463-6472 [2019-03-26; online 2019-03-08]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism—Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers?

Muthu M, Nordström A

Int J Mol Sci 20 (6) 1385 [2019-03-19; online 2019-03-19]

Regulatory Diversification of INDEHISCENT in the Capsella Genus Directs Variation in Fruit Morphology

Dong Y, Jantzen F, Stacey N, ..., Ljung K, Østergaard L

Current Biology 29 (6) 1038-1046.e4 [2019-03-00; online 2019-03-00]

Auxin export from proximal fruits drives arrest in competent inflorescence meristems

Ware A, Walker CH, Šimura J, ..., Wilson Z, Bennett T

- - (-) - [2019-02-06; online 2019-02-06]

Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease

Surowiec I, Noordam R, Bennett K, ..., Lundstedt T, van Heemst D

Metabolomics 15 (2) - [2019-02-00; online 2019-02-12]

DOP15 Metabolomics coupled with pathway analysis characterise metabolic changes in treatment-naive ulcerative colitis patients

Diab J, Hansen T, Goll R, ..., Florholmen J, Forsdahl G

- 13 (Supplement_1) S035-S035 [2019-01-25; online 2019-01-25]

Auxin Function in the Brown Alga Dictyota dichotoma

Bogaert KA, Blommaert L, Ljung K, Beeckman T, De Clerck O

Plant Physiol. 179 (1) 280-299 [2019-01-00; online 2018-11-12]

A standardized protocol for comparable analysis of GSH/GSSG by UHPLC-ESI-MSMS for human plasma

Claeson AS, Gouveia-Figueira S, Stenlund H, Johansson AI

Journal of Chromatography B 1104 (-) 67-72 [2019-01-00; online 2019-01-00]

Tissue-specific hormone profiles from woody poplar roots under bending stress

De Zio E, Trupiano D, Karady M, ..., Ljung K, Scippa GS

Physiol Plantarum 165 (1) 101-113 [2019-01-00; online 2018-10-15]

Joint and unique multiblock analysis of biological data – multiomics malaria study

Surowiec I, Skotare T, Sjögren R, ..., Normark J, Trygg J

Faraday Discuss. 218 (-) 268-283 [2019-00-00; online 2019-00-00]

Year 2018

Rice auxin influx carrier OsAUX1 facilitates root hair elongation in response to low external phosphate

Giri J, Bhosale R, Huang G, ..., Swarup R, Bennett MJ

Nat Commun 9 (1) - [2018-12-00; online 2018-04-12]

A multi-omics approach reveals function of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees

Obudulu O, Mähler N, Skotare T, ..., Trygg J, Tuominen H

BMC Genomics 19 (1) - [2018-12-00; online 2018-01-03]

A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate

Bhosale R, Giri J, Pandey BK, ..., Bennett MJ, Swarup R

Nat Commun 9 (1) - [2018-12-00; online 2018-04-12]

A Quantitative Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Treatment-Naïve and Deep Remission Ulcerative Colitis Patients and the Potential Link With Cytokine Gene Expression

Diab J, Al-Mahdi R, Gouveia-Figueira S, ..., Florholmen J, Forsdahl G

- - (-) - [2018-11-22; online 2018-11-22]

Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother’s Milk Are Strongly Associated with Infant Weight at Four Months of Age—Data from the Odense Child Cohort

Bruun S, Gouveia-Figueira S, Domellöf M, ..., Fowler C, Zachariassen G

Nutrients 10 (11) 1747 [2018-11-13; online 2018-11-13]

Nitrogen utilization during germination of somatic embryos of Norway spruce: revealing the importance of supplied glutamine for nitrogen metabolism

Carlsson J, Egertsdotter U, Ganeteg U, Svennerstam H

Trees - (-) - [2018-11-09; online 2018-11-09]

The Xerobranching Response Represses Lateral Root Formation When Roots Are Not in Contact with Water

Orman-Ligeza B, Morris EC, Parizot B, ..., Beeckman T, Draye X

Current Biology 28 (19) 3165-3173.e5 [2018-10-00; online 2018-10-00]

Broad spectrum developmental role of Brachypodium AUX1

van der Schuren A, Voiniciuc C, Bragg J, ..., Pauly M, Hardtke CS

New Phytol 219 (4) 1216-1223 [2018-09-00; online 2018-06-27]

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

Cedernaes J, Schönke M, Westholm JO, ..., Zierath JR, Benedict C

Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]

Bioinformatics Compute and Storage [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

J. Proteome Res. 17 (7) 2293-2306 [2018-07-06; online 2018-06-06]

A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial

Otten J, Stomby A, Waling M, ..., Hauksson J, Olsson T

Diabetologia 61 (7) 1548-1559 [2018-07-00; online 2018-04-26]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry

Kong Z, Jia S, Chabes AL, ..., Moritz T, Chabes A

Nucleic Acids Res 46 (11) e66-e66 [2018-06-20; online 2018-03-15]

Circadian clock components control daily growth activities by modulating cytokinin levels and cell division-associated gene expression in Populus trees

Edwards KD, Takata N, Johansson M, ..., Ljung K, Eriksson ME

Plant, Cell & Environment 41 (6) 1468-1482 [2018-06-00; online 2018-04-15]

Assessing Cu impacts on freshwater diatoms: biochemical and metabolomic responses of Tabellaria flocculosa (Roth) Kützing

Gonçalves S, Kahlert M, Almeida SFP, Figueira E

Science of The Total Environment 625 (-) 1234-1246 [2018-06-00; online 2018-06-00]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Plant Hormonomics: Multiple Phytohormone Profiling by Targeted Metabolomics

Šimura J, Antoniadi I, Široká J, ..., Ljung K, Novák O

Plant Physiol. 177 (2) 476-489 [2018-06-00; online 2018-04-27]

Ultra-rapid auxin metabolite profiling for high-throughput mutant screening in Arabidopsis

Pěnčík A, Casanova-Sáez R, Pilařová V, ..., Ljung K, Novák O

- 69 (10) 2569-2579 [2018-04-27; online 2018-03-03]

Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

Bergenholm D, Gossing M, Wei Y, Siewers V, Nielsen J

Biotechnol. Bioeng. 115 (4) 932-942 [2018-04-00; online 2018-01-24]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

Transcriptional stimulation of rate-limiting components of the autophagic pathway improves plant fitness

Minina EA, Moschou PN, Vetukuri RR, ..., Hofius D, Bozhkov PV

- 69 (6) 1415-1432 [2018-03-14; online 2018-01-20]

Darkened leaves use different metabolic strategies for senescence and survival

Law SR, Chrobok D, Juvany M, ..., Gardestrom P, Keech O

Plant Physiol. - (-) pp.00062.2018 [2018-03-09; online 2018-03-09]

Interferon γ treatment increases endocannabinoid and related N-acylethanolamine levels in T84 human colon carcinoma cells

Alhouayek M, Rankin L, Gouveia-Figueira S, Fowler CJ

British Journal of Pharmacology - (-) - [2018-02-05; online 2018-02-05]

Red meat intake in chronic kidney disease patients: Two sides of the coin

Mafra D, Borges NA, Cardozo LFMdF, ..., Lindholm B, Stenvinkel P

Nutrition 46 (-) 26-32 [2018-02-00; online 2018-02-00]

Bioinformatics Compute and Storage [Service] Swedish Metabolomics Centre (SMC) [Service]

A Common Peptidolytic Mechanism for Targeting Peptide Degradation in Mitochondria and Chloroplasts

Kmiec B, Branca RMM, Murcha MW, ..., Glaser E, Teixeira PF

Molecular Plant 11 (2) 342-345 [2018-02-00; online 2018-02-00]

Proteogenomics [Service] Swedish Metabolomics Centre (SMC) [Service]

Optimising methods for the recovery and quantification of di- and tripeptides in soil

J�mtg�rd S, Robinson N, Moritz T, Colgrave ML, Schmidt S

Soil Res. - (-) - [2018-00-00; online 2018-00-00]

Year 2017

Metabolome and transcriptome profiling reveal new insights into somatic embryo germination in Norway spruce (Picea abies)

Dobrowolska I, Businge E, Abreu IN, Moritz T, Egertsdotter U

Tree Physiol 37 (12) 1752-1766 [2017-12-01; online 2017-06-28]

Brassinosteroid signaling-dependent root responses to prolonged elevated ambient temperature

Martins S, Montiel-Jorda A, Cayrel A, ..., Ljung K, Vert G

Nat Commun 8 (1) - [2017-12-00; online 2017-08-21]

The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children

Surowiec I, Gouveia-Figueira S, Orikiiriza J, ..., Normark J, Trygg J

Malar. J. 16 (1) - [2017-12-00; online 2017-09-08]

Combined transcriptome and translatome analyses reveal a role for tryptophan-dependent auxin biosynthesis in the control of DOG1-dependent seed dormancy

Bai B, Novák O, Ljung K, Hanson J, Bentsink L

New Phytol - (-) - [2017-11-15; online 2017-11-15]

Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1

Yan Z, Liu X, Ljung K, ..., Wang M, Tao Y

Plant Physiol. 175 (3) 1438-1454 [2017-11-00; online 2017-09-20]

Multivariate strategy for the sample selection and integration of multi-batch data in metabolomics

Surowiec I, Johansson E, Torell F, ..., Jakobsson PJ, Trygg J

Metabolomics 13 (10) - [2017-10-00; online 2017-08-24]

Swedish Metabolomics Centre (SMC) [Technology development]

Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells

Karlsson J, Gouveia-Figueira S, Alhouayek M, Fowler CJ

PLoS ONE 12 (9) e0185011 [2017-09-14; online 2017-09-14]

Auxin minimum triggers the developmental switch from cell division to cell differentiation in theArabidopsisroot

Di Mambro R, De Ruvo M, Pacifici E, ..., Grieneisen VA, Sabatini S

Proc Natl Acad Sci USA 114 (36) E7641-E7649 [2017-09-05; online 2017-08-22]

Enhanced Secondary- and Hormone Metabolism in Leaves of Arbuscular Mycorrhizal Medicago truncatula

Adolfsson L, Nziengui H, Abreu IN, ..., Schoefs B, Spetea C

Plant Physiol. 175 (1) 392-411 [2017-09-00; online 2017-07-11]

Nitrogen uptake and assimilation in proliferating embryogenic cultures of Norway spruce—Investigating the specific role of glutamine

Carlsson J, Svennerstam H, Moritz T, Egertsdotter U, Ganeteg U

PLoS ONE 12 (8) e0181785 [2017-08-24; online 2017-08-24]

Dual herbivore attack and herbivore density affect metabolic profiles of Brassica nigra leaves

Ponzio C, Papazian S, Albrectsen BR, Dicke M, Gols R

Plant, Cell & Environment 40 (8) 1356-1367 [2017-08-00; online 2017-02-24]

Tuning Metabolome Coverage in Reversed Phase LC–MS Metabolomics of MeOH Extracted Samples Using the Reconstitution Solvent Composition

Lindahl A, Sääf S, Lehtiö J, Nordström A

Anal. Chem. 89 (14) 7356-7364 [2017-07-18; online 2017-06-28]

Clinical Proteomics Mass spectrometry [Service] Proteogenomics [Service] Swedish Metabolomics Centre (SMC) [Technology development]

Establishment of photosynthesis is controlled by two distinct regulatory phases

Dubreuil C, Jin X, Barajas-López JdD, ..., Small ID, Strand A

Plant Physiol. - (-) pp.00435.2017 [2017-06-16; online 2017-06-16]

Cryo-EM [Service] Swedish Metabolomics Centre (SMC) [Service]

Levels of oxylipins, endocannabinoids and related lipids in plasma before and after low-level exposure to acrolein in healthy individuals and individuals with chemical intolerance

Claeson AS, Gouveia-Figueira S, Häggström J, Fowler CJ, Nording ML

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 121 (-) 60-67 [2017-06-00; online 2017-06-00]

The effects of thawing on the plasma metabolome: evaluating differences between thawed plasma and multi-organ samples

Torell F, Bennett K, Rännar S, ..., Lundstedt T, Trygg J

Metabolomics 13 (6) - [2017-06-00; online 2017-04-17]

Metabolite quantification by NMR and LC-MS/MS reveals differences between unstimulated, stimulated, and pure parotid saliva

Figueira J, Gouveia-Figueira S, Öhman C, ..., Nording ML, Öhman A

Journal of Pharmaceutical and Biomedical Analysis 140 (-) 295-300 [2017-06-00; online 2017-06-00]

Swedish Metabolomics Centre (SMC) [Service] Swedish NMR Centre (SNC) [Collaborative]

Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa

Näsström E, Parry CM, Vu Thieu NT, ..., Antti H, Baker S

Elife 6 (-) - [2017-05-09; online 2017-05-09]

Regulating plant physiology with organic electronics

Poxson DJ, Karady M, Gabrielsson R, ..., Simon DT, Berggren M

Proc Natl Acad Sci USA 114 (18) 4597-4602 [2017-05-02; online 2017-04-18]

Contrasting patterns of cytokinins between years in senescing aspen leaves

Edlund E, Novak O, Karady M, Ljung K, Jansson S

Plant, Cell & Environment 40 (5) 622-634 [2017-05-00; online 2017-03-27]

Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics

Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A

Metabolomics 13 (5) - [2017-05-00; online 2017-04-01]

Clinical Proteomics Mass spectrometry [Service] Proteogenomics [Service] Swedish Metabolomics Centre (SMC) [Service]

Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria

Orikiiriza J, Surowiec I, Lindquist E, ..., Trygg J, Normark J

Metabolomics 13 (4) - [2017-04-00; online 2017-02-23]

Neonatal Cord Blood Oxylipins and Exposure to Particulate Matter in the Early-Life Environment: An ENVIRONAGE Birth Cohort Study.

Martens DS, Gouveia S, Madhloum N, ..., Nording M, Nawrot TS

pii: EHP291 pmc: PMC5381981

Environ. Health Perspect. 125 (4) 691-698 [2017-04-00; online 2016-11-05]

The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line

Gabrielsson L, Gouveia-Figueira S, Häggström J, Alhouayek M, Fowler CJ

Pharmacol Res Perspect 5 (2) e00300 [2017-04-00; online 2017-02-27]

Altered expression of maize PLASTOCHRON1 enhances biomass and seed yield by extending cell division duration

Sun X, Cahill J, Van Hautegem T, ..., Inzé D, Nelissen H

Nat Commun 8 (-) 14752 [2017-03-16; online 2017-03-16]

Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease

Falkevall A, Mehlem A, Palombo I, ..., Nash A, Eriksson U

Cell Metabolism 25 (3) 713-726 [2017-03-00; online 2017-03-00]

The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth

Weiste C, Pedrotti L, Selvanayagam J, ..., Hanson J, Dröge-Laser W

PLoS Genet. 13 (2) e1006607 [2017-02-03; online 2017-02-03]

Defense Responses in Aspen with Altered Pectin Methylesterase Activity Reveal the Hormonal Inducers of Tyloses

Leśniewska J, Öhman D, Krzesłowska M, ..., Moritz T, Mellerowicz EJ

Plant Physiol. 173 (2) 1409-1419 [2017-02-00; online 2016-12-06]

cis-Cinnamic Acid Is a Novel, Natural Auxin Efflux Inhibitor That Promotes Lateral Root Formation

Steenackers W, Klíma P, Quareshy M, ..., Boerjan W, Vanholme B

Plant Physiol. 173 (1) 552-565 [2017-01-00; online 2016-11-11]

A multi-step peptidolytic cascade for amino acid recovery in chloroplasts

Teixeira PF, Kmiec B, Branca RMM, ..., Lehtiö J, Glaser E

Nat Chem Biol 13 (1) 15-17 [2017-01-00; online 2016-10-31]

Clinical Proteomics Mass spectrometry [Collaborative] Proteogenomics [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

SHADE AVOIDANCE 4 Is Required for Proper Auxin Distribution in the Hypocotyl

Ge Y, Yan F, Zourelidou M, ..., Schwechheimer C, Tao Y

Plant Physiol. 173 (1) 788-800 [2017-01-00; online 2016-11-21]

Year 2016

Aspen phenylpropanoid genes’ expression levels correlate with genets’ tannin richness and vary both in responses to soil nitrogen and associations with phenolic profiles

Decker VHG, Bandau F, Gundale MJ, Cole CT, Albrectsen BR

Tree Physiol - (-) - [2016-12-15; online 2016-12-15]

Dissecting the Metabolic Role of Mitochondria during Developmental Leaf Senescence.

Chrobok D, Law SR, Brouwer B, ..., Gardeström P, Keech O

pii: pp.16.01463 pmc: PMC5129728

Plant Physiol. 172 (4) 2132-2153 [2016-12-00; online 2016-10-21]

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6.

Dobrenel T, Mancera-Martínez E, Forzani C, ..., Hanson J, Meyer C

pmc: PMC5100631

Front Plant Sci 7 (-) 1611 [2016-11-07; online 2016-11-07]

Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure.

Papazian S, Khaling E, Bonnet C, ..., Blande JD, Albrectsen BR

pii: pp.16.01318 pmc: PMC5100778

Plant Physiol. 172 (3) 2057-2078 [2016-11-00; online 2016-10-21]

Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.

Jia M, Andreassen T, Jensen L, ..., Moestue SA, Dahlman-Wright K

pii: 0008-5472.CAN-15-2910

Cancer Res. 76 (19) 5634-5646 [2016-10-01; online 2016-07-28]

Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.

Malm L, Tybring G, Moritz T, Landin B, Galli J

Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]

Direct acquisition of organic N by white clover even in the presence of inorganic N

Czaban W, Jämtgård S, Näsholm T, ..., Nicolaisen M, Fomsgaard IS

Plant Soil 407 (1-2) 91-107 [2016-10-00; online 2016-04-15]

Dioxygenase-encoding AtDAO1 gene controls IAA oxidation and homeostasis in Arabidopsis.

Porco S, Pěnčík A, Rashed A, ..., Bennett MJ, Ljung K

pmc: PMC5047156 pii: 1604375113

Proc. Natl. Acad. Sci. U.S.A. 113 (39) 11016-11021 [2016-09-27; online 2016-09-22]

Loss of ncm(5) and mcm(5) wobble uridine side chains results in an altered metabolic profile.

Karlsborn T, Mahmud AK, Tükenmez H, Byström AS

pii: 1120 pmc: PMC5037161

Metabolomics 12 (12) 177 [2016-09-27; online 2016-09-27]

Overlap in serum metabolic profiles between non-related diseases: Implications for LC-MS metabolomics biomarker discovery.

Lindahl A, Forshed J, Nordström A

pii: S0006-291X(16)31419-X

Biochem. Biophys. Res. Commun. 478 (3) 1472-1477 [2016-09-23; online 2016-09-02]

Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis.

Bengtsson AA, Trygg J, Wuttge DM, ..., Rännar S, Lundstedt T

pii: PONE-D-15-55064 pmc: PMC4956266

PLoS ONE 11 (7) e0159384 [2016-07-21; online 2016-07-21]

Quantitative Auxin Metabolite Profiling Using Stable Isotope Dilution UHPLC-MS/MS

Novák O, Pěnčík A, Blahoušek O, Ljung K

Curr Protoc Plant Biol - (-) 419-430 [2016-06-10; online 2016-06-10]

The Effects of High Steady State Auxin Levels on Root Cell Elongation in Brachypodium.

Pacheco-Villalobos D, Díaz-Moreno SM, van der Schuren A, ..., Bulone V, Hardtke CS

pii: tpc.16.01057

Plant Cell - (-) - [2016-05-05; online 2016-05-05]

Metabolomics study of fatigue in patients with rheumatoid arthritis naïve to biological treatment.

Surowiec I, Gjesdal CG, Jonsson G, ..., Trygg J, Omdal R

pii: 10.1007/s00296-016-3426-2

Rheumatol. Int. 36 (5) 703-711 [2016-05-00; online 2016-01-25]

Reduced mitochondrial malate dehydrogenase activity has a strong effect on photorespiratory metabolism as revealed by 13C labelling.

Lindén P, Keech O, Stenlund H, Gardeström P, Moritz T

pii: erw030 pmc: PMC4867893

J. Exp. Bot. 67 (10) 3123-3135 [2016-05-00; online 2016-02-19]

TOR Signaling and Nutrient Sensing.

Dobrenel T, Caldana C, Hanson J, ..., Veit B, Meyer C

Annu Rev Plant Biol 67 (-) 261-285 [2016-04-29; online 2016-02-26]

PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B.

Mehlem A, Palombo I, Wang X, ..., Eriksson U, Falkevall A

pii: db15-1231

Diabetes 65 (4) 861-873 [2016-04-00; online 2016-01-30]

Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects.

Wuolikainen A, Jonsson P, Ahnlund M, ..., Andersen PM, Trupp M

Mol Biosyst 12 (4) 1287-1298 [2016-04-00; online 2016-02-18]

Local auxin metabolism regulates environment-induced hypocotyl elongation

Zheng Z, Guo Y, Novák O, ..., Noel JP, Chory J

NPLANTS 2 (4) 16025 [2016-03-21; online 2016-03-21]

Rat Prostate Tumor Cells Progress in the Bone Microenvironment to a Highly Aggressive Phenotype.

Bergström SH, Rudolfsson SH, Bergh A

pii: S1476-5586(16)00017-8 pmc: PMC4796808

Neoplasia 18 (3) 152-161 [2016-03-00; online 2016-03-20]

Postprandial metabolomics: A pilot mass spectrometry and NMR study of the human plasma metabolome in response to a challenge meal.

Karimpour M, Surowiec I, Wu J, ..., Zivkovic AM, Nording ML

pii: S0003-2670(15)30040-4

Anal. Chim. Acta 908 (-) 121-131 [2016-02-18; online 2016-01-31]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Quantitative proteomics reveals protein profiles underlying major transitions in aspen wood development.

Obudulu O, Bygdell J, Sundberg B, ..., Trygg J, Wingsle G

pii: 10.1186/s12864-016-2458-z pmc: PMC4758094

BMC Genomics 17 (-) 119 [2016-02-18; online 2016-02-18]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre (SMC) [Service]

Tissue sample stability: thawing effect on multi-organ samples

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

Metabolomics 12 (2) - [2016-02-00; online 2015-12-31]

Metabolites in Blood for Prediction of Bacteremic Sepsis in the Emergency Room.

Kauppi AM, Edin A, Ziegler I, ..., Strålin K, Johansson A

pii: PONE-D-15-21656 pmc: PMC4723089

PLoS ONE 11 (1) e0147670 [2016-01-22; online 2016-01-22]

Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light.

Pedmale UV, Huang SS, Zander M, ..., Ecker JR, Chory J

pii: S0092-8674(15)01642-6 pmc: PMC4721562 mid: NIHMS744236

Cell 164 (1-2) 233-245 [2016-01-14; online 2016-01-05]

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.

Missailidis C, Hällqvist J, Qureshi AR, ..., Stenvinkel P, Bergman P

pii: PONE-D-15-34186 pmc: PMC4709190

PLoS ONE 11 (1) e0141738 [2016-01-11; online 2016-01-11]

Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions.

Wu J, Gouveia-Figueira S, Domellöf M, Zivkovic AM, Nording ML

pii: S1098-8823(15)30017-4

Prostaglandins Other Lipid Mediat. 122 (-) 28-36 [2016-01-00; online 2015-12-15]

Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.

Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A

pii: 10.1007/s12032-015-0717-5 pmc: PMC4689760

Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-25]

Year 2013

Plasma and erythrocyte glutathione peroxidase activity, serum selenium concentration, and plasma total antioxidant capacity in cats with IRIS stages I-IV chronic kidney disease.

Krofič Žel M, Tozon N, Nemec Svete A

pmc: PMC4895542

J. Vet. Intern. Med. 28 (1) 130-136 [2013-12-16; online 2013-12-16]