Clinical Genomics Umeå

DNA methylation variations and epigenetic aging in telomere biology disorders.

Carlund O, Norberg A, Osterman P, ..., Degerman S, Hultdin M

Sci Rep 13 (1) 7955 [2023-05-16; online 2023-05-16]

Plasma Concentrations of Gut Hormones Acyl Ghrelin and Peptide YY and Subsequent Risk of Colorectal Cancer and Molecular Tumor Subtypes.

Bodén S, Harbs J, Sundkvist A, ..., Harlid S, Van Guelpen B

Cancer Prev Res (Phila) 16 (2) 75-87 [2023-02-06; online 2022-11-12]

Immune-Activated B Cells Are Dominant in Prostate Cancer.

Saudi A, Banday V, Zirakzadeh AA, ..., Winqvist O, Sherif A

Cancers (Basel) 15 (3) - [2023-02-01; online 2023-02-01]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Umeå [Service]

Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer.

Lidström T, Cumming J, Gaur R, ..., Patthey C, Öhlund D

Cancer Immunol Res 11 (1) 72-92 [2023-01-03; online 2022-12-09]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Umeå [Service]

Year 2022

Parvimonas micra is associated with tumour immune profiles in molecular subtypes of colorectal cancer.

Löwenmark T, Li X, Löfgren-Burström A, ..., Edin S, Palmqvist R

Cancer Immunol. Immunother. 71 (10) 2565-2575 [2022-10-00; online 2022-03-17]

Affinity Proteomics Uppsala [Service] Clinical Genomics Umeå [Service]

Implementing precision medicine in a regionally organized healthcare system in Sweden.

Fioretos T, Wirta V, Cavelier L, ..., Edsjö A, Rosenquist R

Nat. Med. 28 (10) 1980-1982 [2022-10-00; online 2022-09-20]

Clinical Genomics Gothenburg [Collaborative] Clinical Genomics Linköping [Service] Clinical Genomics Stockholm [Collaborative] Clinical Genomics Umeå [Service] Clinical Genomics Uppsala [Collaborative]

To Modify or Not to Modify: Allele-Specific Effects of 3'UTR-KCNQ1 Single Nucleotide Polymorphisms on Clinical Phenotype in a Long QT 1 Founder Population Segregating a Dominant-Negative Mutation.

Winbo A, Diamant UB, Persson J, Jensen SM, Rydberg A

J Am Heart Assoc 11 (18) e025981 [2022-09-20; online 2022-09-14]

TCF4 trinucleotide repeat expansion in Swedish cases with Fuchs' endothelial corneal dystrophy.

Viberg A, Westin IM, Golovleva I, Byström B

Acta Ophthalmol 100 (5) 541-548 [2022-08-00; online 2021-10-13]

Long-Term Follow-Up of Newborns with 22q11 Deletion Syndrome and Low TRECs

Framme JL, Lundqvist C, Lundell AC, ..., Oskarsdóttir S, Ekwall O

J Clin Immunol 42 (3) 618-633 [2022-04-00; online 2022-01-26]

A Study Protocol for Validation and Implementation of Whole-Genome and -Transcriptome Sequencing as a Comprehensive Precision Diagnostic Test in Acute Leukemias.

Berglund E, Barbany G, Orsmark-Pietras C, ..., Fioretos T, Rosenquist R

Front Med (Lausanne) 9 (-) 842507 [2022-03-24; online 2022-03-24]

Clinical Genomics Gothenburg [Collaborative] Clinical Genomics Stockholm [Collaborative] Clinical Genomics Umeå [Service] Clinical Genomics Uppsala [Collaborative]

Clinical and biological relevance of the transcriptomic-based prostate cancer metastasis subtypes MetA-C.

Thysell E, Köhn L, Semenas J, ..., Bergh A, Wikström P

Mol Oncol 16 (4) 846-859 [2022-02-00; online 2021-12-27]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Genomics Umeå [Service]

Year 2021

A modified protein marker panel to identify four consensus molecular subtypes in colorectal cancer using immunohistochemistry.

Li X, Larsson P, Ljuslinder I, ..., Edin S, Palmqvist R

Pathol Res Pract 220 (-) 153379 [2021-04-00; online 2021-03-05]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Umeå [Collaborative]

Year 2020

Parvimonas micra as a putative non-invasive faecal biomarker for colorectal cancer.

Löwenmark T, Löfgren-Burström A, Zingmark C, ..., Edin S, Palmqvist R

Sci Rep 10 (1) 15250 [2020-09-17; online 2020-09-17]

DNA methylation and copy number variation profiling of T-cell lymphoblastic leukemia and lymphoma.

Haider Z, Landfors M, Golovleva I, ..., Hultdin M, Degerman S

Blood Cancer J 10 (4) 45 [2020-04-28; online 2020-04-28]

Ex Vivo Organoid Cultures Reveal the Importance of the Tumor Microenvironment for Maintenance of Colorectal Cancer Stem Cells.

Li X, Larsson P, Ljuslinder I, ..., Edin S, Palmqvist R

Cancers (Basel) 12 (4) 923 [2020-04-10; online 2020-04-10]

Year 2019

An integrated transcriptome analysis in T-cell acute lymphoblastic leukemia links DNA methylation subgroups to dysregulated TAL1 and ANTP homeobox gene expression.

Haider Z, Larsson P, Landfors M, ..., Hultdin M, Degerman S

Cancer Med 8 (1) 311-324 [2019-01-00; online 2018-12-21]