Haematologica

Aberrant MNX1 expression associated with t(7;12)(q36;p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation.

Waraky A, Östlund A, Nilsson T, ..., Plass C, Palmqvist L

Haematologica 109 (3) 725-739 [2024-03-01; online 2024-03-01]

Glycoproteomics and MS Proteomics [Service]

Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia.

Ingelman-Sundberg HM, Blixt L, Wullimann D, ..., Buggert M, Österborg A

Haematologica 109 (2) 646-651 [2024-02-01; online 2024-02-01]

Affinity Proteomics Uppsala [Collaborative]

PVT1 interacts with polycomb repressive complex 2 to suppress genomic regions with pro-apoptotic and tumour suppressor functions in multiple myeloma.

Nylund P, Garrido-Zabala B, Párraga AA, ..., Kalushkova A, Wiklund HJ

Haematologica - (-) - [2023-07-27; online 2023-07-27]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative]

Platelet proteome and function in X-linked thrombocytopenia with thalassemia and in silico comparisons with gray platelet syndrome.

Bergemalm D, Ramström S, Kardeby C, ..., Palmblad J, Åström M

Haematologica 106 (11) 2947-2959 [2021-11-01; online 2021-11-01]

Glycoproteomics and MS Proteomics [Collaborative]

Comparative analysis of targeted next-generation sequencing panels for the detection of gene mutations in chronic lymphocytic leukemia: an ERIC multi-center study.

Sutton L, Ljungström V, Enjuanes A, ..., Stamatopoulos K, Rosenquist R

Haematologica 106 (3) 682-691 [2021-03-01; online 2021-03-01]

Clinical Genomics Uppsala [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells.

Li H, Lim HC, Zacharaki D, ..., Hansson J, Scheding S

Haematologica 105 (5) 1206-1215 [2020-05-00; online 2019-08-01]

Clinical Genomics Lund [Service]

Single-molecule DNA sequencing of acute myeloid leukemia and myelodysplastic syndromes with multiple TP53 alterations.

Lodé L, Ameur A, Coste T, ..., Lavabre-Bertrand T, Soussi T

Haematologica 103 (1) e13-e16 [2018-01-00; online 2017-10-27]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Distinct global binding patterns of the Wilms tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells.

Ullmark T, Järvstråt L, Sandén C, ..., Nilsson B, Gullberg U

Haematologica 102 (2) 336-345 [2017-02-00; online 2016-09-09]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond.

Rosenquist R, Rosenwald A, Du MQ, ..., Stamatopoulos K, European Research Initiative on CLL (ERIC) and the European Association for Haematopathology (EAHP)

Haematologica 101 (9) 1002-1009 [2016-09-00; online 2016-09-02]

Clinical Genomics Uppsala [Collaborative]

ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres.

Navrkalova V, Young E, Baliakas P, ..., Rosenquist R, Trbusek M

Haematologica 101 (9) e369-e373 [2016-09-00; online 2016-08-02]

Clinical Genomics Uppsala [Service]

Innovation in the prognostication of chronic lymphocytic leukemia: how far beyond TP53 gene analysis can we go?

Pospisilova S, Sutton LA, Malcikova J, ..., Ghia P, European Research Initiative on CLL (ERIC)

Haematologica 101 (3) 263-265 [2016-03-00; online 2016-03-02]

Clinical Genomics Uppsala [Service]

PAX5-ESRRB is a recurrent fusion gene in B-cell precursor pediatric acute lymphoblastic leukemia.

Marincevic-Zuniga Y, Zachariadis V, Cavelier L, ..., Syvänen AC, Nordlund J

Haematologica 101 (1) e20-e23 [2016-01-00; online 2015-10-22]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Uppsala [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Collaborative] National Genomics Infrastructure [Collaborative]

High-throughput mutational screening adds clinically important information in myelodysplastic syndromes and secondary or therapy-related acute myeloid leukemia.

Karimi M, Nilsson C, Dimitriou M, ..., Kere J, Hellström-Lindberg E

Haematologica 100 (6) e223-e225 [2015-06-00; online 2015-03-15]

Mutation Analysis Facility (MAF) NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure

Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting.

Sutton LA, Ljungström V, Mansouri L, ..., Stamatopoulos K, Rosenquist R

Haematologica 100 (3) 370-376 [2015-03-00; online 2014-12-07]

Clinical Genomics Uppsala

p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q).

Saft L, Karimi M, Ghaderi M, ..., MacBeth KJ, Hellström-Lindberg E

Haematologica 99 (6) 1041-1049 [2014-06-00; online 2014-04-01]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure

High modal number and triple trisomies are highly correlated favorable factors in childhood B-cell precursor high hyperdiploid acute lymphoblastic leukemia treated according to the NOPHO ALL 1992/2000 protocols.

Paulsson K, Forestier E, Andersen MK, ..., Swedish Cytogenetic Leukemia Study Group (SCLSG) , NOPHO Leukemia Cytogenetic Study Group (NLCSG)

Haematologica 98 (9) 1424-1432 [2013-09-00; online 2013-05-03]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure

Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia.

Gunnarsson R, Mansouri L, Isaksson A, ..., Juliusson G, Rosenquist R

Haematologica 96 (8) 1161-1169 [2011-08-00; online 2011-05-07]

Array and Analysis Facility NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure

Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.

Marincevic M, Mansouri M, Kanduri M, ..., Stamatopoulos K, Rosenquist R

Haematologica 95 (12) 2072-2079 [2010-12-00; online 2010-08-31]

Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure

High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors.

Marincevic M, Cahill N, Gunnarsson R, ..., Stamatopoulos K, Rosenquist R

Haematologica 95 (9) 1519-1525 [2010-09-00; online 2010-04-28]

Array and Analysis Facility