Boren J

Aging AdipoR2-deficient mice are hyperactive with enlarged brains excessively rich in saturated fatty acids.

Ruiz M, Devkota R, Bergh PO, ..., Borén J, Pilon M

FASEB J. 38 (14) e23815 [2024-07-31; online 2024-07-11]

Integrated Microscopy Technologies Gothenburg [Service]

Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.

Altay O, Yang H, Yildirim S, ..., Turkez H, Mardinoglu A

Biomedicines 12 (4) - [2024-04-22; online 2024-04-22]

Bioinformatics Support for Computational Resources [Service]

Cardiomyocyte-specific PCSK9 deficiency compromises mitochondrial bioenergetics and heart function.

Laudette M, Lindbom M, Arif M, ..., Levin MC, Borén J

Cardiovasc. Res. 119 (7) 1537-1552 [2023-07-04; online 2023-03-08]

Integrated Microscopy Technologies Gothenburg [Service]

Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and embryogenesis.

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Nat Commun 13 (1) 7162 [2022-11-22; online 2022-11-22]

Glycoproteomics and MS Proteomics [Service]

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Taskinen MR, Matikainen N, Björnson E, ..., Packard CJ, Borén J

Eur. J. Endocrinol. 187 (1) 75-84 [2022-07-01; online 2022-05-19]

Glycoproteomics and MS Proteomics [Service]

The role of circulating galectin-1 in type 2 diabetes and chronic kidney disease: evidence from cross-sectional, longitudinal and Mendelian randomisation analyses.

Drake I, Fryk E, Strindberg L, ..., Orho-Melander M, Jansson PA

Diabetologia - (-) - [2021-11-07; online 2021-11-07]

Affinity Proteomics Uppsala [Service]

Combined metabolic activators therapy ameliorates liver fat in nonalcoholic fatty liver disease patients.

Zeybel M, Altay O, Arif M, ..., Borén J, Mardinoglu A

Mol. Syst. Biol. 17 (10) e10459 [2021-10-00; online 2021-10-26]

Affinity Proteomics Stockholm [Collaborative]

Effects of liraglutide on the metabolism of triglyceride‐rich lipoproteins in type 2 diabetes

Taskinen M, Björnson E, Matikainen N, ..., Packard CJ, Borén J

Diabetes Obes Metab 23 (5) 1191-1201 [2021-05-00; online 2021-03-05]

Glycoproteomics and MS Proteomics [Collaborative]

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.

Busayavalasa K, Ruiz M, Devkota R, ..., Borén J, Pilon M

PLoS Genet. 16 (8) e1008975 [2020-08-00; online 2020-08-04]

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The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.

Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A

Mol. Syst. Biol. 16 (4) e9495 [2020-04-00; online 2020-04-28]

Affinity Proteomics Stockholm [Service] Bioinformatics Support for Computational Resources [Service]

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome.

Lovric A, Granér M, Bjornson E, ..., Mardinoglu A, Boren J

Sci Rep 8 (1) 14200 [2018-09-21; online 2018-09-21]

Affinity Proteomics Uppsala [Service] Clinical Biomarkers [Service] PLA and Single Cell Proteomics [Service]

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids.

Devkota R, Svensk E, Ruiz M, ..., Borén J, Pilon M

PLoS Genet. 13 (9) e1007004 [2017-09-00; online 2017-09-08]

Integrated Microscopy Technologies Gothenburg [Service]