Akke M

Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit.

Stenström O, Diehl C, Modig K, Akke M

Proc. Natl. Acad. Sci. U.S.A. 121 (14) e2317747121 [2024-04-02; online 2024-03-25]

Swedish NMR Centre (SNC) [Service]

Conformational Dynamics of Phytoglobin BvPgb1.2 from Beta vulgaris ssp. vulgaris.

Christensen S, Stenström O, Akke M, Bülow L

Int J Mol Sci 24 (4) - [2023-02-16; online 2023-02-16]

Swedish NMR Centre (SNC) [Service]

Entropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C.

Wallerstein J, Ekberg V, Ignjatović MM, ..., Ryde U, Akke M

JACS Au 1 (4) 484-500 [2021-04-26; online 2021-04-01]

Swedish NMR Centre (SNC) [Collaborative]

Mapping the energy landscape of protein-ligand binding via linear free energy relationships determined by protein NMR relaxation dispersion.

Stenström O, Diehl C, Modig K, Nilsson UJ, Akke M

RSC Chem Biol 2 (1) 259-265 [2021-02-01; online 2020-12-23]

Swedish NMR Centre (SNC) [Service]

Dynamic allosteric communication pathway directing differential activation of the glucocorticoid receptor.

Köhler C, Carlström G, Gunnarsson A, ..., Edman K, Akke M

Sci Adv 6 (29) eabb5277 [2020-07-00; online 2020-07-17]

Swedish NMR Centre (SNC) [Service]

Backbone 1H, 13C, and 15N resonance assignments of BoMan26A, a β-mannanase of the glycoside hydrolase family 26 from the human gut bacterium Bacteroides ovatus.

Wernersson S, Bågenholm V, Persson C, ..., Stålbrand H, Akke M

Biomol NMR Assign 13 (1) 213-218 [2019-04-00; online 2019-02-07]

Swedish NMR Centre (SNC) [Service]

Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding.

Verteramo ML, Stenström O, Ignjatović MM, ..., Ryde U, Akke M

J. Am. Chem. Soc. 141 (5) 2012-2026 [2019-02-06; online 2019-01-23]

Swedish NMR Centre (SNC) [Service]

Backbone 1H, 13C, and 15N resonance assignments of the ligand binding domain of the human wildtype glucocorticoid receptor and the F602S mutant variant

Köhler C, Carlström G, Tångefjord S, ..., Edman K, Akke M

Biomol NMR Assign 12 (2) 263-268 [2018-10-00; online 2018-04-17]

Swedish NMR Centre (SNC) [Service]

Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant.

Khan MAI, Respondek M, Kjellström S, ..., Linse S, Akke M

ACS Chem Neurosci 8 (9) 2019-2026 [2017-09-20; online 2017-06-20]

Structural Proteomics [Service]

Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD.

Quistgaard EM, Weininger U, Ural-Blimke Y, ..., Akke M, Löw C

BMC Biol. 14 (1) 82 [2016-09-23; online 2016-09-23]

Protein Science Facility (PSF) [Service]

Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO.

Diehl C, Akke M, Bekker-Jensen S, ..., Streicher W, Wikström M

J. Biol. Chem. 291 (24) 12658-12672 [2016-06-10; online 2016-04-25]

Swedish NMR Centre (SNC) [Service]