Unemo M

In silico gepotidacin target mining among 33 213 global Neisseria gonorrhoeae genomes from 1928 to 2023 combined with gepotidacin MIC testing of 22 gonococcal isolates with different GyrA and ParC substitutions.

David A, Golparian D, Jacobsson S, ..., Davies C, Unemo M

J. Antimicrob. Chemother. 79 (9) 2221-2226 [2024-09-03; online 2024-07-15]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

The novel 2024 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations and superseded WHO N. gonorrhoeae reference strains-phenotypic, genetic and reference genome characterization.

Unemo M, Sánchez-Busó L, Golparian D, ..., Wi T, Lahra MM

J. Antimicrob. Chemother. 79 (8) 1885-1899 [2024-08-01; online 2024-06-18]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Pharmacodynamic evaluation of ceftriaxone single-dose therapy (0.125-1 g) to eradicate ceftriaxone-susceptible and ceftriaxone-resistant Neisseria gonorrhoeae strains in a hollow fibre infection model for gonorrhoea.

Unemo M, Golparian D, Oxelbark J, ..., Drusano G, Jacobsson S

J. Antimicrob. Chemother. 79 (5) 1006-1013 [2024-05-02; online 2024-03-18]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Recent dynamics in Neisseria gonorrhoeae genomic epidemiology in Brazil: antimicrobial resistance and genomic lineages in 2017-20 compared to 2015-16.

Golparian D, Bazzo ML, Ahlstrand J, ..., Unemo M, Brazilian-GASP Network

J. Antimicrob. Chemother. 79 (5) 1081-1092 [2024-05-02; online 2024-03-22]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing.

Sangprasert P, Golparian D, Paopang P, ..., Kittiyaowanarn R, Unemo M

Microbiol Resour Announc 13 (3) e0123123 [2024-03-12; online 2024-02-01]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Genomic surveillance and antimicrobial resistance determinants in Neisseria gonorrhoeae isolates from Uganda, Malawi and South Africa, 2015-20.

Kakooza F, Golparian D, Matoga M, ..., Wi T, Unemo M

J. Antimicrob. Chemother. 78 (8) 1982-1991 [2023-08-02; online 2023-06-23]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

High-level in vitro resistance to gentamicin acquired in a stepwise manner in Neisseria gonorrhoeae.

Golparian D, Jacobsson S, Holley CL, Shafer WM, Unemo M

J. Antimicrob. Chemother. 78 (7) 1769-1778 [2023-07-05; online 2023-05-30]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Complete Reference Genome Sequence of the Clinical Neisseria gonorrhoeae Strain H035, with Resistance to the Novel Antimicrobial Zoliflodacin, Identified in Japan in 2000.

Golparian D, Jacobsson S, Ohnishi M, Unemo M

Microbiol Resour Announc 12 (3) e0113022 [2023-03-16; online 2023-02-28]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

GyrB in silico mining in 27 151 global gonococcal genomes from 1928-2021 combined with zoliflodacin in vitro testing of 71 international gonococcal isolates with different GyrB, ParC and ParE substitutions confirms high susceptibility.

Golparian D, Jacobsson S, Sánchez-Busó L, ..., Ohnishi M, Unemo M

J. Antimicrob. Chemother. - (-) - [2022-10-29; online 2022-10-29]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Complete Reference Genome Sequence of the Extensively Drug-Resistant Strain Neisseria gonorrhoeae AT159, with Ceftriaxone Resistance and High-Level Azithromycin Resistance, Using Nanopore Q20+ Chemistry and Illumina Sequencing.

Golparian D, Pleininger S, Jacobsson S, Indra A, Unemo M

Microbiol Resour Announc 11 (9) e0074422 [2022-09-15; online 2022-08-25]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Genomic surveillance and antimicrobial resistance in Neisseria gonorrhoeae isolates in Bangkok, Thailand in 2018.

Golparian D, Kittiyaowamarn R, Paopang P, ..., Wi T, Unemo M

J. Antimicrob. Chemother. 77 (8) 2171-2182 [2022-07-28; online 2022-05-12]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]

Genomic epidemiology of Neisseria gonorrhoeae elucidating the gonococcal antimicrobial resistance and lineages/sublineages across Brazil, 2015-16.

Golparian D, Bazzo ML, Golfetto L, ..., Unemo M, Brazilian-GASP Network

J. Antimicrob. Chemother. 75 (11) 3163-3172 [2020-11-01; online 2020-08-14]

Clinical Genomics [Technology development] Clinical Genomics Örebro [Technology development]

Genomic analysis and antimicrobial resistance of Neisseria gonorrhoeae isolates from Vietnam in 2011 and 2015-16.

Lan PT, Golparian D, Ringlander J, ..., Van Thuong N, Unemo M

J. Antimicrob. Chemother. 75 (6) 1432-1438 [2020-06-01; online 2020-02-19]

Clinical Genomics [Collaborative] Clinical Genomics Örebro [Collaborative]