Publications 2018

Title Authors Journal Published Online
Gene expression correlated with delay in shell formation in larval Pacific oysters (Crassostrea gigas) exposed to experimental ocean acidification provides insights into shell formation mechanisms De Wit P, Durland E, Ventura A, Langdon CJ BMC Genomics 19 (1) - 2018-12-00 2018-02-22
A major locus controls local adaptation and adaptive life history variation in a perennial plant Wang J, Ding J, ..., Street NR, Ingvarsson PK Genome Biol. 19 (1) - 2018-12-00 2018-06-04
Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow Zhu Y, Orre LM, ..., Branca RMM, Lehtiö J Nat Commun 9 (1) - 2018-12-00 2018-03-02
Comparative omics and feeding manipulations in chicken indicate a shift of the endocrine role of visceral fat towards reproduction Bornelöv S, Seroussi E, ..., Andersson L, Friedman-Einat M BMC Genomics 19 (1) - 2018-12-00 2018-04-26
Somatic mutagenesis in satellite cells associates with human skeletal muscle aging Franco I, Johansson A, ..., Fischer H, Eriksson M Nat Commun 9 (1) - 2018-12-00 2018-02-23
Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin Johansson HJ, Vallhov H, ..., Lehtiö J, Scheynius A Sci Rep 8 (1) - 2018-12-00 2018-06-15
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage Ladds MJGW, van Leeuwen IMM, ..., McCormack E, Laín S Nat Commun 9 (1) - 2018-12-00 2018-03-16
Effects of predation stress and food ration on perch gut microbiota Zha Y, Eiler A, Johansson F, Svanbäck R Microbiome 6 (1) - 2018-12-00 2018-02-06
RNA-sequencing reveals long-term effects of silver nanoparticles on human lung cells Gliga AR, Di Bucchianico S, ..., Fadeel B, Karlsson HL Sci Rep 8 (1) - 2018-12-00 2018-04-27
Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells Page BDG, Valerie NCK, ..., Beato M, Helleday T Nat Commun 9 (1) - 2018-12-00 2018-01-17
Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin Johansson HJ, Vallhov H, ..., Lehtiö J, Scheynius A Sci Rep 8 (1) - 2018-12-00 2018-06-15
A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons Södersten E, Toskas K, ..., Perlmann T, Holmberg J Nat Commun 9 (1) - 2018-12-00 2018-03-26
Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells Kundu S, Ali MA, ..., Hellström M, Sjöblom T Genome Med 10 (1) - 2018-12-00 2018-01-04
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. Feitosa MF, Kraja AT, ..., Province MA, Levy D PLoS ONE 13 (6) e0198166 2018-06-18 2018-06-18
CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response Haapaniemi E, Botla S, ..., Schmierer B, Taipale J Nat Med - (-) - 2018-06-11 2018-06-11
Topology of membrane proteins — predictions, limitations and variations Tsirigos KD, Govindarajan S, ..., Shu N, Elofsson A Current Opinion in Structural Biology 50 (-) 9-17 2018-06-00 2018-06-00
Equilibrative nucleoside transporter 1 gene polymorphisms and clinical outcomes following acute coronary syndromes: findings from the PLATelet inhibition and patient Outcomes (PLATO) study. Parker WAE, Eriksson N, ..., Storey RF, PLATO Investigators Platelets - (-) 1-10 2018-05-31 2018-05-31
Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison's disease in Sweden. Eriksson D, Bianchi M, ..., Rosengren Pielberg G, Kämpe O Sci Rep 8 (1) 8395 2018-05-30 2018-05-30
Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Davies G, Lam M, ..., Lencz T, Deary IJ Nat Commun 9 (1) 2098 2018-05-29 2018-05-29
A genome-wide association study of IgM antibody against phosphorylcholine: shared genetics and phenotypic relationship to chronic lymphocytic leukemia. Chen X, Gustafsson S, ..., Frostegård J, Magnusson PKE Hum. Mol. Genet. 27 (10) 1809-1818 2018-05-15 2018-03-17
Habitual coffee consumption and cognitive function: a Mendelian randomization meta-analysis in up to 415,530 participants. Zhou A, Taylor AE, ..., Llewellyn DJ, Hyppönen E Sci Rep 8 (1) 7526 2018-05-14 2018-05-14
Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variants Garcia M, Juhos S, ..., Nystedt B, Käller M - - (-) - 2018-05-09 2018-05-09
Genome-wide association meta-analysis of circulating odd-numbered chain saturated fatty acids: Results from the CHARGE Consortium. de Oliveira Otto MC, Lemaitre RN, ..., Siscovick DS, Mozaffarian D PLoS ONE 13 (5) e0196951 2018-05-08 2018-05-08
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression. Wray NR, Ripke S, ..., Sullivan PF, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium Nat. Genet. 50 (5) 668-681 2018-05-00 2018-04-26
Mitochondrial Translation Efficiency Controls Cytoplasmic Protein Homeostasis Suhm T, Kaimal JM, ..., Andréasson C, Ott M Cell Metabolism - (-) - 2018-05-00 2018-05-00
Transcription profiling of peripheral B cells in antibody-positive primary Sjögren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature Imgenberg-Kreuz J, Sandling JK, ..., Syvänen AC, Nordmark G Scand J Immunol 87 (5) e12662 2018-05-00 2018-04-18
DNA methylation mapping identifies gene regulatory effects in patients with systemic lupus erythematosus. Imgenberg-Kreuz J, Carlsson Almlöf J, ..., Syvänen AC, Sandling JK Ann. Rheum. Dis. 77 (5) 736-743 2018-05-00 2018-02-01
Quantification of endogenous and exogenous protein expressions of Na,K-ATPase with super-resolution PALM/STORM imaging Bernhem K, Blom H, Brismar H PLoS ONE 13 (4) e0195825 2018-04-25 2018-04-25
Experimental validation of predicted cancer genes using FRET Guala D, Bernhem K, ..., Brismar H, Sonnhammer ELL Methods Appl. Fluoresc. 6 (3) 035007 2018-04-25 2018-04-25
Eleven loci with new reproducible genetic associations with allergic disease risk. Ferreira MAR, Vonk JM, ..., Koppelman GH, Paternoster L J. Allergy Clin. Immunol. - (-) - 2018-04-19 2018-04-19
A GWAS meta-analysis from 5 population-based cohorts implicates ion channel genes in the pathogenesis of irritable bowel syndrome. Bonfiglio F, Henström M, ..., Zhernakova A, D'Amato M Neurogastroenterol. Motil. - (-) e13358 2018-04-19 2018-04-19
Data quality of whole genome bisulfite sequencing on Illumina platforms. Raine A, Liljedahl U, Nordlund J PLoS ONE 13 (4) e0195972 2018-04-18 2018-04-18
Genetic and Environmental Contributions to the Covariation Between Cardiometabolic Traits. Chen X, Kuja-Halkola R, ..., Pedersen NL, Magnusson PKE J Am Heart Assoc 7 (9) - 2018-04-18 2018-04-18
Ezerskyte M, Paredes JA, ..., Scicchitano DA, Dreij K Proc. Natl. Acad. Sci. U.S.A. - (-) - 2018-04-17 2018-04-17
Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Morgunova E, Yin Y, ..., Nilsson L, Taipale J Elife 7 (-) - 2018-04-11 2018-04-11
Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions Spiess M, Hernandez-Varas P, ..., Lakadamyali M, Strömblad S J. Cell Biol. - (-) jcb.201707075 2018-04-09 2018-04-09
Female-specific Association Between Variants on Chromosome 9 and Self-reported Diagnosis of Irritable Bowel Syndrome. Bonfiglio F, Zheng T, ..., Zhernakova A, D'Amato M Gastroenterology - (-) - 2018-04-04 2018-04-04
Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor Boerema AP, Aibara S, ..., Lindahl E, Amunts A NPLANTS 4 (4) 212-217 2018-04-00 2018-04-02
Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol Ekblad T, Verheugd P, ..., Elofsson M, Schüler H SLAS DISCOVERY: Advancing Life Sciences R&D 23 (4) 353-362 2018-04-00 2018-01-09
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. Malik R, Chauhan G, ..., MEGASTROKE Consortium , MEGASTROKE Consortium: Nat. Genet. 50 (4) 524-537 2018-04-00 2018-03-12
Changes in methylation within the STK32B promoter are associated with an increased risk for generalized anxiety disorder in adolescents. Ciuculete DM, Boström AE, ..., Mwinyi J, Schiöth HB J Psychiatr Res 102 (-) 44-51 2018-03-26 2018-03-26
Protein Expression in Tonsillar and Base of Tongue Cancer and in Relation to Human Papillomavirus (HPV) and Clinical Outcome Ramqvist T, Näsman A, ..., Dalianis T, Munck-Wikland E Int J Mol Sci 19 (4) 978 2018-03-25 2018-03-25
A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood. Jiang J, Thalamuthu A, ..., Sachdev PS, Mather KA Front Genet 9 (-) 97 2018-03-23 2018-03-23
Recurrent, low-frequency coding variants contributing to colorectal cancer in the Swedish population. Jiao X, Liu W, ..., Dunlop M, Lindblom A PLoS ONE 13 (3) e0193547 2018-03-16 2018-03-16
Increased thermal stability of nanocellulose composites by functionalization of the sulfate groups on cellulose nanocrystals with azetidinium ions Börjesson M, Sahlin K, Bernin D, Westman G J. Appl. Polym. Sci. 135 (10) 45963 2018-03-10 2017-11-08
Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals. Coleman JRI, Bryois J, ..., Posthuma D, Breen G Mol. Psychiatry - (-) - 2018-03-08 2018-03-08
Novel gene variants associated with cardiovascular disease in systemic lupus erythematosus and rheumatoid arthritis. Leonard D, Svenungsson E, ..., Criswell LA, Rönnblom L Ann. Rheum. Dis. - (-) - 2018-03-07 2018-03-07
The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability. Hafstrand I, Doorduijn EM, ..., van Hall T, Achour A J. Immunol. - (-) - 2018-03-05 2018-03-05
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. Sung YJ, Winkler TW, ..., Rao DC, Chasman DI Am. J. Hum. Genet. 102 (3) 375-400 2018-03-01 2018-02-15
Genetic variants influencing phenotypic variance heterogeneity. Ek WE, Rask-Andersen M, ..., Gyllensten U, Johansson Å Hum. Mol. Genet. 27 (5) 799-810 2018-03-01 2018-01-13
Sexual dimorphism in the width of the mouse synaptonemal complex Agostinho A, Kouznetsova A, ..., Brismar H, Höög C J Cell Sci 131 (5) jcs212548 2018-03-01 2018-02-02
The fungus that came in from the cold: dry rot’s pre-adapted ability to invade buildings Balasundaram SV, Hess J, ..., Eastwood DC, Skrede I ISME J 12 (3) 791-801 2018-03-00 2018-01-05
Functional metagenomics reveals a novel carbapenem-hydrolyzing mobile beta-lactamase from Indian river sediments contaminated with antibiotic production waste Marathe NP, Janzon A, ..., Kristiansson E, Larsson DGJ Environment International 112 (-) 279-286 2018-03-00 2018-03-00
Cleaner fish escape salmon farms and hybridize with local wrasse populations Faust E, Halvorsen KT, ..., Knutsen H, André C R. Soc. open sci. 5 (3) 171752 2018-03-00 2018-03-21
The ZBED6–IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals Younis S, Schönke M, ..., Zierath JR, Andersson L Proc Natl Acad Sci USA 115 (9) E2048-E2057 2018-02-27 2018-02-12
The Hagberg N, Joelsson M, ..., Bryceson YT, Rönnblom L Ann. Rheum. Dis. - (-) - 2018-02-23 2018-02-23
Targeted Long-Read Sequencing of a Locus Under Long-Term Balancing Selection in Capsella Bachmann JA, Tedder A, ..., Steige KA, Slotte T G3 (Bethesda) - (-) g3.300467.2017 2018-02-23 2018-02-23
In Situ Target Engagement Studies in Adherent Cells Axelsson H, Almqvist H, ..., Lundbäck T, Seashore-Ludlow B ACS Chem. Biol. - (-) - 2018-02-21 2018-02-21
Two novel colorectal cancer risk loci in the region on chromosome 9q22.32 Thutkawkorapin J, Mahdessian H, ..., Jiao X, Lindblom A Oncotarget 9 (13) - 2018-02-16 2018-01-30
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. Stafford WC, Peng X, ..., Linder S, Arnér ESJ Sci Transl Med 10 (428) - 2018-02-14 2018-02-16
Educated natural killer cells show dynamic movement of the activating receptor NKp46 and confinement of the inhibitory receptor Ly49A Staaf E, Hedde PN, ..., Gratton E, Johansson S Sci. Signal. 11 (517) eaai9200 2018-02-13 2018-02-13
Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation. Agudelo LZ, Ferreira DMS, ..., Berggren P, Ruas JL Cell Metab. 27 (2) 378-392.e5 2018-02-06 2018-02-08
Ten steps to get started in Genome Assembly and Annotation Dominguez Del Angel V, Hjerde E, ..., Binzer-Panchal M, Lantz H F1000Res 7 (-) 148 2018-02-05 2018-02-05
Single molecule real-time (SMRT) sequencing comes of age: applications and utilities for medical diagnostics Ardui S, Ameur A, Vermeesch JR, Hestand MS Nucleic Acids Res - (-) - 2018-02-01 2018-02-01
Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration Pettersson-Klein AT, Izadi M, ..., Griffin PR, Ruas JL Mol Metab - (-) - 2018-02-00 2018-02-00
Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders. Stamouli S, Anderlid BM, ..., Tammimies K, Bölte S Twin Res Hum Genet 21 (1) 1-11 2018-02-00 2018-01-08
Life after tree death: Does restored dead wood host different fungal communities to natural woody substrates? Pasanen H, Junninen K, ..., Stenlid J, Kouki J Forest Ecology and Management 409 (-) 863-871 2018-02-00 2018-02-00
Red meat intake in chronic kidney disease patients: Two sides of the coin Mafra D, Borges NA, ..., Lindholm B, Stenvinkel P Nutrition 46 (-) 26-32 2018-02-00 2018-02-00
Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold Carter M, Jemth AS, ..., Helleday T, Stenmark P Structure 26 (2) 295-303.e6 2018-02-00 2018-02-00
A DNA methylation biomarker of alcohol consumption. Liu C, Marioni RE, ..., Ingelsson E, Levy D Mol. Psychiatry 23 (2) 422-433 2018-02-00 2016-11-15
T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus Houtman M, Shchetynsky K, ..., Malmström V, Padyukov L Journal of Autoimmunity - (-) - 2018-02-00 2018-02-00
Archaeal community changes in Lateglacial lake sediments: Evidence from ancient DNA Ahmed E, Parducci L, ..., Slotte T, Wohlfarth B Quaternary Science Reviews 181 (-) 19-29 2018-02-00 2018-02-00
Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing Davidsson M, Díaz-Fernández P, ..., Lundberg C, Bjorklund T RNA - (-) rna.063925.117 2018-01-31 2018-01-31
A comprehensive model of DNA fragmentation for the preservation of High Molecular Weight DNA Klingstrom T, Bongcam-Rudloff E, Vinnere Pettersson O - - (-) - 2018-01-27 2018-01-27
In Situ Analyses Directly in Diarrheal Stool Reveal Large Variations in Bacterial Load and Active Toxin Expression of Enterotoxigenic Escherichia coli and Vibrio cholerae Begum YA, Rydberg HA, ..., Qadri F, Sjöling Å mSphere 3 (1) e00517-17 2018-01-24 2018-01-24
Genetical genomics of growth in a chicken model. Johnsson M, Henriksen R, ..., Jensen P, Wright D BMC Genomics 19 (1) 72 2018-01-23 2018-01-23
Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Jiang X, O'Reilly PF, ..., Kraft P, Kiel DP Nat Commun 9 (1) 260 2018-01-17 2018-01-17
Extensive genomic diversity among Mycobacterium marinum strains revealed by whole genome sequencing Das S, Pettersson F, ..., Ennis DG, Kirsebom L - - (-) - 2018-01-17 2018-01-17
Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity Narwal M, Jemth AS, ..., Helleday T, Stenmark P Biochemistry - (-) - 2018-01-16 2018-01-16
Complete genomic and transcriptional landscape analysis using third-generation sequencing: a case study of Saccharomyces cerevisiae CEN.PK113-7D Jenjaroenpun P, Wongsurawat T, ..., Nielsen J, Nookaew I Nucleic Acids Res - (-) - 2018-01-13 2018-01-13
Rapid hybrid speciation in Darwin’s finches Lamichhaney S, Han F, ..., Grant BR, Grant PR Science 359 (6372) 224-228 2018-01-12 2017-11-23
Identification of shared genetic variants between schizophrenia and lung cancer. Zuber V, Jönsson EG, ..., Mills IG, Andreassen OA Sci Rep 8 (1) 674 2018-01-12 2018-01-12
Population genomics of Mesolithic Scandinavia: Investigating early postglacial migration routes and high-latitude adaptation Günther T, Malmström H, ..., Götherström A, Jakobsson M PLoS Biol. 16 (1) e2003703 2018-01-09 2018-01-09
A protein interaction network centered on leucine-rich repeats and immunoglobulin-like domains 1 (LRIG1) regulates growth factor receptors Faraz M, Herdenberg C, ..., Henriksson R, Hedman H J. Biol. Chem. - (-) jbc.M117.807487 2018-01-09 2018-01-09
Evaluating vacquinol-1 in rats carrying glioblastoma models RG2 and NS1 Ahlstedt J, Förnvik K, ..., Salford LG, Redebrandt HN Oncotarget - (-) - 2018-01-03 2018-01-03
Cytokine Autoantibody Screening in the Swedish Addison Registry Identifies Patients With Undiagnosed APS1 Eriksson D, Dalin F, ..., Munoz KD, None J Clin Endocrinol Metab 103 (1) 179-186 2018-01-01 2017-10-20
Minimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative. Rydén L, Loman N, ..., Saal LH, Borg Å Br J Surg 105 (2) e158-e168 2018-01-00 2018-01-18
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Turcot V, Lu Y, ..., MAGIC Investigators , Understanding Society Scientific Group Nat. Genet. 50 (1) 26-41 2018-01-00 2017-12-22
Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents. Jokinen J, Boström AE, ..., Åsberg M, Schiöth HB EBioMedicine 27 (-) 123-133 2018-01-00 2017-12-18
Genomic consequences of intensive inbreeding in an isolated wolf population Kardos M, Åkesson M, ..., Wikenros C, Ellegren H Nat Ecol Evol 2 (1) 124-131 2018-01-00 2017-11-20
The SubCons webserver: A user friendly web interface for state-of-the-art subcellular localization prediction. Salvatore M, Shu N, Elofsson A Protein Sci. 27 (1) 195-201 2018-01-00 2017-10-24
Single-molecule DNA sequencing of acute myeloid leukemia and myelodysplastic syndromes with multiple TP53 alterations Lodé L, Ameur A, ..., Lavabre-Bertrand T, Soussi T Haematologica 103 (1) e13-e16 2018-01-00 2017-10-27
Homozygosity for a missense variant in COMP gene associated with severe pseudoachondroplasia Tariq M, Khan TN, ..., Dahl N, Klar J Clin Genet 93 (1) 182-186 2018-01-00 2017-11-21