Uhlén M

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Family name Uhlén
Given name Mathias
Initials M
ORCID

ORCID 0000-0002-4858-8056
Affiliations Science for Life Laboratory, Department of Protein Science, KTH Royal Institute of Technology, Stockholm, Sweden.
Center for Biosustainability, Danish Technical University, Copenhagen, Denmark.

163 publications

PubMed DOI Crossref
The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern.
Zhong W, Danielsson H, Brusselaers N, ..., Uhlén M, Hellström A
Commun Med (Lond) 3 (1) 107 [2023-08-02; online 2023-08-02]
Affinity Proteomics Stockholm [Service]
PubMed DOI Crossref
Next generation pan-cancer blood proteome profiling using proximity extension assay.
Álvez MB, Edfors F, von Feilitzen K, ..., Fagerberg L, Uhlén M
Nat Commun 14 (1) 4308 [2023-07-18; online 2023-07-18]
Affinity Proteomics Uppsala [Collaborative] Bioinformatics Support for Computational Resources [Service] NGI Proteomics [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Collaborative] National Genomics Infrastructure [Collaborative]
PubMed DOI Crossref
Identification of Endothelial Proteins in Plasma Associated With Cardiovascular Risk Factors.
Iglesias MJ, Kruse LD, Sanchez-Rivera L, ..., Odeberg J, Butler LM
Arterioscler. Thromb. Vasc. Biol. 41 (12) 2990-3004 [2021-12-00; online 2021-10-28]
Affinity Proteomics Stockholm [Service]
PubMed DOI Crossref
Immunoglobulin A Autoreactivity toward Brain Enriched and Apoptosis-Regulating Proteins in Saliva of Athletes after Acute Concussion and Subconcussive Impacts.
Pin E, Petricoin EF, Cortes N, ..., Nilsson P, Caswell SV
J. Neurotrauma 38 (17) 2373-2383 [2021-09-01; online 2021-05-24]
Autoimmunity and Serology Profiling [Collaborative]
PubMed DOI Crossref
Genome-scale metabolic network reconstruction of model animals as a platform for translational research.
Wang H, Robinson JL, Kocabas P, ..., Zetterberg H, Nielsen J
Proc. Natl. Acad. Sci. U.S.A. 118 (30) e2102344118 [2021-07-27; online 2021-07-21]
Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Systems Biology [Technology development]
PubMed DOI Crossref
High Amounts of SARS-CoV-2 Precede Sickness Among Asymptomatic Health Care Workers.
Dillner J, Elfström KM, Blomqvist J, ..., Arroyo Mühr LS, Lundgren KC
J. Infect. Dis. 224 (1) 14-20 [2021-07-02; online 2021-02-14]
Autoimmunity and Serology Profiling [Service]
PubMed DOI Crossref
A single-cell type transcriptomics map of human tissues.
Karlsson M, Zhang C, Méar L, ..., Uhlén M, Lindskog C
Sci Adv 7 (31) eabh2169 [2021-07-00; online 2021-07-28]
Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative]
PubMed DOI Crossref
Allergome-wide peptide microarrays enable epitope deconvolution in allergen-specific immunotherapy
Mikus M, Zandian A, Sjöberg R, ..., van Hage M, Ohlin M
Journal of Allergy and Clinical Immunology 147 (3) 1077-1086 [2021-03-00; online 2021-03-00]
Autoimmunity and Serology Profiling [Collaborative]
PubMed DOI Crossref
Spatiotemporal dissection of the cell cycle with single-cell proteogenomics.
Mahdessian D, Cesnik AJ, Gnann C, ..., Sullivan DP, Lundberg E
Nature 590 (7847) 649-654 [2021-02-00; online 2021-02-24]
Eukaryotic Single Cell Genomics (ESCG) [Service] NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics [Collaborative]
PubMed DOI Crossref
Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes.
Gummesson A, Björnson E, Fagerberg L, ..., Uhlén M, Bergström G
EBioMedicine 63 (-) 103147 [2021-01-00; online 2020-12-03]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Exploring autoantibody signatures in brain tissue from patients with severe mental illness.
Just D, Månberg A, Mitsios N, ..., Nilsson P, Carlström EL
Transl Psychiatry 10 (1) 401 [2020-11-18; online 2020-11-18]
Autoimmunity and Serology Profiling [Collaborative]
PubMed DOI Crossref
A high-stringency blueprint of the human proteome.
Adhikari S, Nice EC, Deutsch EW, ..., Aebersold R, Baker MS
Nat Commun 11 (1) 5301 [2020-10-16; online 2020-10-16]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Profiles of histidine-rich glycoprotein associate with age and risk of all-cause mortality.
Hong MG, Dodig-Crnković T, Chen X, ..., Magnusson PK, Schwenk JM
Life Sci. Alliance 3 (10) e202000817 [2020-10-00; online 2020-07-31]
Affinity Proteomics Stockholm [Collaborative] Autoimmunity and Serology Profiling [Service] Bioinformatics Support for Computational Resources [Service]
PubMed DOI Crossref
Integration of molecular profiles in a longitudinal wellness profiling cohort.
Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L
Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]
Affinity Proteomics Stockholm [Collaborative] Autoimmunity and Serology Profiling [Collaborative] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Cellular Immunomonitoring [Collaborative] Swedish Metabolomics Centre (SMC) [Collaborative]
PubMed DOI Crossref
Human Immune System Variation during 1 Year.
Lakshmikanth T, Muhammad SA, Olin A, ..., Uhlen M, Brodin P
Cell Rep 32 (3) 107923 [2020-07-21; online 2020-07-23]
Affinity Proteomics Stockholm [Service] Bioinformatics Support for Computational Resources [Service] Cellular Immunomonitoring [Technology development]
PubMed DOI Crossref
Facets of individual-specific health signatures determined from longitudinal plasma proteome profiling.
Dodig-Crnković T, Hong MG, Thomas CE, ..., Uhlén M, Schwenk JM
EBioMedicine 57 (-) 102854 [2020-07-00; online 2020-07-03]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Whole-genome sequence association analysis of blood proteins in a longitudinal wellness cohort.
Zhong W, Gummesson A, Tebani A, ..., Fagerberg L, Uhlén M
Genome Med 12 (1) 53 [2020-06-23; online 2020-06-23]
Affinity Proteomics Stockholm [Collaborative] Bioinformatics Support for Computational Resources [Service]
PubMed DOI Crossref
Altered levels of CSF proteins in patients with FTD, presymptomatic mutation carriers and non-carriers.
Remnestål J, Öijerstedt L, Ullgren A, ..., Graff C, Nilsson P
Transl Neurodegener 9 (1) 27 [2020-06-23; online 2020-06-23]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
Genome-Scale Metabolic Modeling of Glioblastoma Reveals Promising Targets for Drug Development.
Larsson I, Uhlén M, Zhang C, Mardinoglu A
Front Genet 11 (-) 381 [2020-04-17; online 2020-04-17]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease.
Zhang C, Bjornson E, Arif M, ..., Borén J, Mardinoglu A
Mol. Syst. Biol. 16 (4) e9495 [2020-04-00; online 2020-04-28]
Affinity Proteomics Stockholm [Service] Bioinformatics Support for Computational Resources [Service]
PubMed DOI Crossref
An atlas of human metabolism.
Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J
Sci Signal 13 (624) - [2020-03-24; online 2020-03-24]
Bioinformatics Support, Infrastructure and Training [Technology development] Systems Biology [Technology development]
PubMed DOI Crossref
An atlas of the protein-coding genes in the human, pig, and mouse brain.
Sjöstedt E, Zhong W, Fagerberg L, ..., Uhlén M, Mulder J
Science 367 (6482) eaay5947 [2020-03-06; online 2020-03-07]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
A genome-wide transcriptomic analysis of protein-coding genes in human blood cells.
Uhlen M, Karlsson MJ, Zhong W, ..., Fagerberg L, Brodin P
Science 366 (6472) - [2019-12-20; online 2019-12-21]
Bioinformatics Support for Computational Resources [Service] Cellular Immunomonitoring [Technology development] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
Cell Type-Specific Expression of Testis Elevated Genes Based on Transcriptomics and Antibody-Based Proteomics.
Pineau C, Hikmet F, Zhang C, ..., Uhlén M, Lindskog C
J. Proteome Res. 18 (12) 4215-4230 [2019-12-06; online 2019-08-29]
NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
The human secretome
Uhlén M, Karlsson MJ, Hober A, ..., Fagerberg L, Sivertsson Å
Sci. Signal. 12 (609) eaaz0274 [2019-11-26; online 2019-11-26]
Affinity Proteomics Stockholm [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Spatial Proteomics [Collaborative]
PubMed DOI Crossref
Multiplexed analysis of the secretin-like GPCR-RAMP interactome.
Lorenzen E, Dodig-Crnković T, Kotliar IB, ..., Schwenk JM, Sakmar TP
Sci Adv 5 (9) eaaw2778 [2019-09-00; online 2019-09-18]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Systematic Development of Sandwich Immunoassays for the Plasma Secretome.
Häussler RS, Bendes A, Iglesias M, ..., Qundos U, Schwenk JM
Proteomics 19 (15) e1900008 [2019-08-00; online 2019-07-22]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Screening a Resource of Recombinant Protein Fragments for Targeted Proteomics.
Edfors F, Forsström B, Vunk H, ..., Schwenk JM, Uhlen M
J. Proteome Res. 18 (7) 2706-2718 [2019-07-05; online 2019-06-07]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease.
Andersson A, Remnestål J, Nellgård B, ..., Nilsson P, Fredolini C
Clin. Chim. Acta 494 (-) 79-93 [2019-07-00; online 2019-03-09]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
SAMURAI (Solid-phase Assisted Mutagenesis by Uracil Restriction for Accurate Integration) for antibody affinity maturation and paratope mapping.
Hu FJ, Lundqvist M, Uhlén M, Rockberg J
Nucleic Acids Res. 47 (6) e34 [2019-04-08; online 2019-02-05]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues.
Wang D, Eraslan B, Wieland T, ..., Hahne H, Kuster B
Mol. Syst. Biol. 15 (2) e8503 [2019-02-18; online 2019-02-18]
NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
Individual and stable autoantibody repertoires in healthy individuals.
Neiman M, Hellström C, Just D, ..., Uhlén M, Nilsson P
Autoimmunity 52 (1) 1-11 [2019-02-00; online 2019-03-05]
Autoimmunity and Serology Profiling [Collaborative]
PubMed DOI Crossref
Combination of phage and Gram-positive bacterial display of human antibody repertoires enables isolation of functional high affinity binders.
Hu FJ, Volk AL, Persson H, ..., Uhlen M, Rockberg J
N Biotechnol 45 (-) 80-88 [2018-10-25; online 2017-08-01]
Drug Discovery and Development (DDD) [Technology development]
PubMed DOI Crossref
Enhanced validation of antibodies for research applications.
Edfors F, Hober A, Linderbäck K, ..., Forsström B, Uhlen M
Nat Commun 9 (1) 4130 [2018-10-08; online 2018-10-08]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein.
Dusart P, Fagerberg L, Perisic L, ..., Odeberg J, Butler LM
Sci Rep 8 (1) 14668 [2018-10-02; online 2018-10-02]
Spatial Proteomics [Service]
PubMed DOI Crossref
Transcriptome profiling of the interconnection of pathways involved in malignant transformation and response to hypoxia.
Danielsson F, Fasterius E, Sullivan D, ..., Williams C, Lundberg E
Oncotarget 9 (28) 19730-19744 [2018-04-13; online 2018-04-13]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans.
Mardinoglu A, Wu H, Bjornson E, ..., Taskinen MR, Borén J
Cell Metab. 27 (3) 559-571.e5 [2018-03-06; online 2018-02-15]
Affinity Proteomics Uppsala [Service] Clinical Biomarkers [Service] PLA and Single Cell Proteomics [Service]
PubMed DOI Crossref
In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation.
Zieba A, Ponten F, Uhlén M, Landegren U
Mod. Pathol. 31 (2) 253-263 [2018-02-00; online 2017-09-22]
Affinity Proteomics Uppsala [Technology development] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] PLA and Single Cell Proteomics [Technology development] Tissue Profiling [Collaborative]
PubMed DOI Crossref
A pathology atlas of the human cancer transcriptome.
Uhlen M, Zhang C, Lee S, ..., Mardinoglu A, Ponten F
Science 357 (6352) eaan2507 [2017-08-18; online 2017-08-19]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Tissue Profiling [Technology development]
PubMed DOI Crossref
Untargeted screening for novel autoantibodies with prognostic value in first-episode psychosis.
Zandian A, Wingård L, Nilsson H, ..., Nilsson P, Persson MAA
Transl Psychiatry 7 (7) e1177 [2017-07-25; online 2017-07-25]
Autoimmunity and Serology Profiling [Collaborative] Tissue Profiling [Collaborative]
PubMed DOI Crossref
Affinity Proteomics Exploration of Melanoma Identifies Proteins in Serum with Associations to T-Stage and Recurrence.
Byström S, Fredolini C, Edqvist PH, ..., Pontén F, Schwenk JM
Transl Oncol 10 (3) 385-395 [2017-06-00; online 2017-04-20]
Affinity Proteomics Stockholm [Collaborative] Tissue Profiling [Collaborative]
PubMed DOI Crossref
A subcellular map of the human proteome.
Thul PJ, Åkesson L, Wiking M, ..., Uhlén M, Lundberg E
Science 356 (6340) - [2017-05-26; online 2017-05-11]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Spatial Proteomics [Collaborative]
PubMed DOI Crossref
Type 2 diabetes and obesity induce similar transcriptional reprogramming in human myocytes.
Väremo L, Henriksen TI, Scheele C, ..., Pedersen BK, Nielsen J
Genome Med 9 (1) 47 [2017-05-25; online 2017-05-25]
Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
FZD10-Gα13 signalling axis points to a role of FZD10 in CNS angiogenesis.
Hot B, Valnohova J, Arthofer E, ..., Mulder J, Schulte G
Cell. Signal. 32 (-) 93-103 [2017-04-00; online 2017-01-24]
Fluorescence Tissue Profiling [Collaborative]
PubMed DOI Crossref
Whole-Proteome Peptide Microarrays for Profiling Autoantibody Repertoires within Multiple Sclerosis and Narcolepsy.
Zandian A, Forsström B, Häggmark-Månberg A, ..., Nilsson P, Ayoglu B
J. Proteome Res. 16 (3) 1300-1314 [2017-03-03; online 2017-02-09]
Autoimmunity and Serology Profiling [Technology development]
PubMed DOI Crossref
A novel RNA sequencing data analysis method for cell line authentication.
Fasterius E, Raso C, Kennedy S, ..., Uhlén M, Al-Khalili Szigyarto C
PLoS ONE 12 (2) e0171435 [2017-02-13; online 2017-02-13]
NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]
PubMed DOI Crossref
The Human Adrenal Gland Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Bergman J, Botling J, Fagerberg L, ..., Uhlén M, Pontén F
Endocrinology 158 (2) 239-251 [2017-02-01; online 2016-12-03]
Bioinformatics Support for Computational Resources [Service] Clinical Genomics Uppsala [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Tissue Profiling [Technology development]
PubMed DOI Crossref
Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.
Romanov RA, Zeisel A, Bakker J, ..., Horvath TL, Harkany T
Nat. Neurosci. 20 (2) 176-188 [2017-02-00; online 2016-12-19]
Fluorescence Tissue Profiling [Collaborative]
PubMed DOI Crossref
Identification of a Novel Autoimmune Peptide Epitope of Prostein in Prostate Cancer.
Pin E, Henjes F, Hong MG, ..., Nilsson P, Schwenk JM
J. Proteome Res. 16 (1) 204-216 [2017-01-06; online 2016-10-05]
Autoimmunity and Serology Profiling [Collaborative]
PubMed DOI Crossref
Antibody Validation in Bioimaging Applications Based on Endogenous Expression of Tagged Proteins.
Skogs M, Stadler C, Schutten R, ..., Uhlén M, Lundberg E
J. Proteome Res. 16 (1) 147-155 [2017-01-06; online 2016-10-12]
Spatial Proteomics [Technology development]
PubMed DOI Crossref
A systematic search strategy identifies cubilin as independent prognostic marker for renal cell carcinoma.
Gremel G, Djureinovic D, Niinivirta M, ..., Stewart GD, Pontén F
BMC Cancer 17 (1) 9 [2017-01-04; online 2017-01-04]
Tissue Profiling [Technology development]
PubMed DOI Crossref
Elevated levels of circulating CDH5 and FABP1 in association with human drug-induced liver injury.
Mikus M, Drobin K, Gry M, ..., Nilsson P, Schuppe-Koistinen I
Liver Int. 37 (1) 132-140 [2017-01-00; online 2016-05-26]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study.
Bruzelius M, Iglesias MJ, Hong MG, ..., Trégouët DA, Odeberg J
Blood 128 (23) e59-e66 [2016-12-08; online 2016-10-14]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
CSF profiling of the human brain enriched proteome reveals associations of neuromodulin and neurogranin to Alzheimer's disease.
Remnestål J, Just D, Mitsios N, ..., Nilsson P, Häggmark-Månberg A
Proteomics Clin Appl 10 (12) 1242-1253 [2016-12-00; online 2016-10-10]
Affinity Proteomics Stockholm [Collaborative] Fluorescence Tissue Profiling [Collaborative]
PubMed DOI Crossref
ANLN is a prognostic biomarker independent of Ki-67 and essential for cell cycle progression in primary breast cancer.
Magnusson K, Gremel G, Rydén L, ..., Jirström K, Pontén F
BMC Cancer 16 (1) 904 [2016-11-18; online 2016-11-18]
Tissue Profiling [Technology development]
PubMed DOI Crossref
Gene-specific correlation of RNA and protein levels in human cells and tissues.
Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M
Mol. Syst. Biol. 12 (10) 883 [2016-10-20; online 2016-10-20]
NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Tissue Profiling [Collaborative]
PubMed DOI Crossref
A proposal for validation of antibodies.
Uhlen M, Bandrowski A, Carr S, ..., Snyder M, Yamamoto T
Nat. Methods 13 (10) 823-827 [2016-10-00; online 2016-09-05]
Spatial Proteomics [Collaborative]
PubMed DOI Crossref
Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.
Butler LM, Hallström BM, Fagerberg L, ..., Renné T, Odeberg J
Cell Syst 3 (3) 287-301.e3 [2016-09-28; online 2016-09-15]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Exploration of high-density protein microarrays for antibody validation and autoimmunity profiling.
Sjöberg R, Mattsson C, Andersson E, ..., Ayoglu B, Nilsson P
N Biotechnol 33 (5 Pt A) 582-592 [2016-09-25; online 2015-09-30]
Autoimmunity and Serology Profiling [Technology development]
PubMed DOI Crossref
Autoantibody targets in vaccine-associated narcolepsy.
Häggmark-Månberg A, Zandian A, Forsström B, ..., Olsson T, Nilsson P
Autoimmunity 49 (6) 421-433 [2016-09-00; online 2016-05-20]
Autoimmunity and Serology Profiling [Collaborative]
PubMed DOI Crossref
Profiling cancer testis antigens in non-small-cell lung cancer.
Djureinovic D, Hallström BM, Horie M, ..., Uhlén M, Micke P
JCI Insight 1 (10) e86837 [2016-07-07; online 2016-07-07]
Bioinformatics Support for Computational Resources [Service] Clinical Genomics Uppsala [Collaborative] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Tissue Profiling [Collaborative]
PubMed DOI Crossref
Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients.
Hamsten C, Wiklundh E, Grönlund H, ..., Grunewald J, Häggmark-Månberg A
Respir. Res. 17 (1) 69 [2016-06-04; online 2016-06-04]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Transcriptomics resources of human tissues and organs.
Uhlén M, Hallström BM, Lindskog C, ..., Pontén F, Nielsen J
Mol. Syst. Biol. 12 (4) 862 [2016-04-04; online 2016-04-04]
Bioinformatics Support, Infrastructure and Training [Technology development] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Systems Biology [Technology development] Tissue Profiling [Collaborative]
PubMed DOI Crossref
Multiplexed protein profiling by sequential affinity capture.
Ayoglu B, Birgersson E, Mezger A, ..., Nilsson P, Schwenk JM
Proteomics 16 (8) 1251-1256 [2016-04-00; online 2016-03-31]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Anoctamin 2 identified as an autoimmune target in multiple sclerosis.
Ayoglu B, Mitsios N, Kockum I, ..., Olsson T, Nilsson P
Proc. Natl. Acad. Sci. U.S.A. 113 (8) 2188-2193 [2016-02-23; online 2016-02-09]
Autoimmunity and Serology Profiling [Collaborative] Fluorescence Tissue Profiling [Collaborative]
PubMed DOI Crossref
The Urinary Bladder Transcriptome and Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Habuka M, Fagerberg L, Hallström BM, ..., Yamamoto T, Uhlen M
PLoS ONE 10 (12) e0145301 [2015-12-22; online 2015-12-22]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling [Collaborative]
PubMed DOI Crossref
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.
Dijksterhuis JP, Arthofer E, Marinescu VD, ..., Mulder J, Schulte G
Exp. Cell Res. 339 (2) 280-288 [2015-12-10; online 2015-10-25]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Immunocapture strategies in translational proteomics.
Fredolini C, Byström S, Pin E, ..., Nilsson P, Schwenk JM
Expert Rev Proteomics 13 (1) 83-98 [2015-11-11; online 2015-11-11]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
The Human Endometrium-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling.
Zieba A, Sjöstedt E, Olovsson M, ..., Uhlen M, Ponten F
OMICS 19 (11) 659-668 [2015-11-00; online 2015-10-21]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling [Technology development]
PubMed DOI Crossref
Microfluidic screening and whole-genome sequencing identifies mutations associated with improved protein secretion by yeast.
Huang M, Bai Y, Sjostrom SL, ..., Andersson-Svahn H, Nielsen J
Proc. Natl. Acad. Sci. U.S.A. 112 (34) E4689-E4696 [2015-08-25; online 2015-08-12]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
Complementing tissue characterization by integrating transcriptome profiling from the Human Protein Atlas and from the FANTOM5 consortium.
Yu NY, Hallström BM, Fagerberg L, ..., Uhlén M, Daub CO
Nucleic Acids Res. 43 (14) 6787-6798 [2015-08-18; online 2015-06-27]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling [Collaborative]
PubMed DOI Crossref
Heat differentiated complement factor profiling.
Hamsten C, Skattum L, Truedsson L, ..., Nilsson P, Neiman M
J Proteomics 126 (-) 155-162 [2015-08-03; online 2015-06-07]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Analysis of the Human Prostate-Specific Proteome Defined by Transcriptomics and Antibody-Based Profiling Identifies TMEM79 and ACOXL as Two Putative, Diagnostic Markers in Prostate Cancer.
O'Hurley G, Busch C, Fagerberg L, ..., Uhlén M, Pontén F
PLoS ONE 10 (8) e0133449 [2015-08-03; online 2015-08-03]
Affinity Proteomics Stockholm NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics Tissue Profiling [Technology development]
PubMed DOI Crossref
The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling.
Lindskog C, Linné J, Fagerberg L, ..., Pontén F, Uhlén M
BMC Genomics 16 (-) 475 [2015-06-25; online 2015-06-25]
Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Tissue Profiling [Collaborative]
PubMed DOI Crossref
Defining the Human Brain Proteome Using Transcriptomics and Antibody-Based Profiling with a Focus on the Cerebral Cortex.
Sjöstedt E, Fagerberg L, Hallström BM, ..., Uhlén M, Mulder J
PLoS ONE 10 (6) e0130028 [2015-06-15; online 2015-06-15]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling [Collaborative]
PubMed DOI Crossref
Loss of ASRGL1 expression is an independent biomarker for disease-specific survival in endometrioid endometrial carcinoma.
Edqvist PH, Huvila J, Forsström B, ..., Pontén F, Auranen A
Gynecol. Oncol. 137 (3) 529-537 [2015-06-00; online 2015-04-07]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Expression of human skin-specific genes defined by transcriptomics and antibody-based profiling.
Edqvist PH, Fagerberg L, Hallström BM, ..., Uhlén M, Pontén F
J. Histochem. Cytochem. 63 (2) 129-141 [2015-02-00; online 2014-11-19]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling [Technology development]
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Proteomics. Tissue-based map of the human proteome.
Uhlén M, Fagerberg L, Hallström BM, ..., Nielsen J, Pontén F
Science 347 (6220) 1260419 [2015-01-23; online 2015-01-24]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics Tissue Profiling [Technology development]
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A secretagogin locus of the mammalian hypothalamus controls stress hormone release.
Romanov RA, Alpár A, Zhang MD, ..., Hökfelt T, Harkany T
EMBO J. 34 (1) 36-54 [2015-01-02; online 2014-11-27]
Fluorescence Tissue Profiling
PubMed DOI Crossref
The human gastrointestinal tract-specific transcriptome and proteome as defined by RNA sequencing and antibody-based profiling.
Gremel G, Wanders A, Cedernaes J, ..., Uhlén M, Pontén F
J. Gastroenterol. 50 (1) 46-57 [2015-01-00; online 2014-05-03]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling
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The lung-specific proteome defined by integration of transcriptomics and antibody-based profiling.
Lindskog C, Fagerberg L, Hallström B, ..., Pontén F, Micke P
FASEB J. 28 (12) 5184-5196 [2014-12-00; online 2014-08-28]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling [Collaborative]
PubMed DOI Crossref
Defining the human adipose tissue proteome to reveal metabolic alterations in obesity.
Mardinoglu A, Kampf C, Asplund A, ..., Uhlen M, Nielsen J
J. Proteome Res. 13 (11) 5106-5119 [2014-11-07; online 2014-09-16]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling
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Affinity proteomic profiling of plasma, cerebrospinal fluid, and brain tissue within multiple sclerosis.
Byström S, Ayoglu B, Häggmark A, ..., Nilsson P, Schwenk JM
J. Proteome Res. 13 (11) 4607-4619 [2014-11-07; online 2014-09-19]
Affinity Proteomics Stockholm [Collaborative] Fluorescence Tissue Profiling
PubMed DOI Crossref
Defining the human gallbladder proteome by transcriptomics and affinity proteomics.
Kampf C, Mardinoglu A, Fagerberg L, ..., Pontén F, Uhlen M
Proteomics 14 (21-22) 2498-2507 [2014-11-00; online 2014-09-02]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling
PubMed DOI Crossref
Analysis of candidate genes for lineage-specific expression changes in humans and primates.
Lindskog C, Kuhlwilm M, Davierwala A, ..., Pääbo S, Pontén F
J. Proteome Res. 13 (8) 3596-3606 [2014-08-01; online 2014-07-15]
Tissue Profiling
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Plasma profiling reveals three proteins associated to amyotrophic lateral sclerosis.
Häggmark A, Mikus M, Mohsenchian A, ..., Kuźma-Kozakiewicz M, Nilsson P
Ann Clin Transl Neurol 1 (8) 544-553 [2014-08-00; online 2014-07-14]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Peroxiredoxin-1 protects estrogen receptor α from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer.
O'Leary PC, Terrile M, Bajor M, ..., Zagozdzon R, Gallagher WM
Breast Cancer Res. 16 (4) R79 [2014-07-10; online 2014-07-10]
Tissue Profiling
PubMed DOI Crossref
The human liver-specific proteome defined by transcriptomics and antibody-based profiling.
Kampf C, Mardinoglu A, Fagerberg L, ..., Nielsen J, Uhlen M
FASEB J. 28 (7) 2901-2914 [2014-07-00; online 2014-03-22]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics Tissue Profiling
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Affinity proteomics within rare diseases: a BIO-NMD study for blood biomarkers of muscular dystrophies.
Ayoglu B, Chaouch A, Lochmüller H, ..., Nilsson P, Al-Khalili Szigyarto C
EMBO Mol Med 6 (7) 918-936 [2014-07-00; online 2014-06-13]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Immunoproteomics using polyclonal antibodies and stable isotope-labeled affinity-purified recombinant proteins.
Edfors F, Boström T, Forsström B, ..., Mann M, Uhlen M
Mol. Cell Proteomics 13 (6) 1611-1624 [2014-06-00; online 2014-04-12]
Spatial Proteomics
PubMed DOI Crossref
Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays.
Forsström B, Axnäs BB, Stengele K, ..., Rockberg J, Uhlen M
Mol. Cell Proteomics 13 (6) 1585-1597 [2014-06-00; online 2014-04-08]
Autoimmunity and Serology Profiling [Technology development]
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The human testis-specific proteome defined by transcriptomics and antibody-based profiling.
Djureinovic D, Fagerberg L, Hallström B, ..., Uhlén M, Pontén F
Mol. Hum. Reprod. 20 (6) 476-488 [2014-06-00; online 2014-03-07]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Tissue Profiling
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The role of SATB2 as a diagnostic marker for tumors of colorectal origin: Results of a pathology-based clinical prospective study.
Dragomir A, de Wit M, Johansson C, Uhlen M, Pontén F
Am. J. Clin. Pathol. 141 (5) 630-638 [2014-05-00; online 2014-04-10]
Tissue Profiling
PubMed DOI Crossref
RNA- and antibody-based profiling of the human proteome with focus on chromosome 19.
Stadler C, Fagerberg L, Sivertsson Å, ..., Lundberg E, Uhlén M
J. Proteome Res. 13 (4) 2019-2027 [2014-04-04; online 2014-03-04]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics
PubMed DOI Crossref
Affinity proteomics reveals elevated muscle proteins in plasma of children with cerebral malaria.
Bachmann J, Burté F, Pramana S, ..., Fernandez-Reyes D, Nilsson P
PLoS Pathog. 10 (4) e1004038 [2014-04-00; online 2014-04-17]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury.
Zhang MD, Tortoriello G, Hsueh B, ..., Harkany T, Hökfelt TG
Proc. Natl. Acad. Sci. U.S.A. 111 (12) E1149-E1158 [2014-03-25; online 2014-03-13]
Fluorescence Tissue Profiling
PubMed DOI Crossref
Identification of anticancer drugs for hepatocellular carcinoma through personalized genome-scale metabolic modeling.
Agren R, Mardinoglu A, Asplund A, ..., Uhlen M, Nielsen J
Mol. Syst. Biol. 10 (-) 721 [2014-03-19; online 2014-03-19]
Tissue Profiling
PubMed DOI Crossref
A chromosome-centric analysis of antibodies directed toward the human proteome using Antibodypedia.
Alm T, von Feilitzen K, Lundberg E, Sivertsson Å, Uhlén M
J. Proteome Res. 13 (3) 1669-1676 [2014-03-07; online 2014-02-19]
Spatial Proteomics
PubMed DOI Crossref
Molecular- and organelle-based predictive paradigm underlying recovery by left ventricular assist device support.
Liem DA, Nsair A, Setty SP, ..., Ping P, Deng MC
Circ Heart Fail 7 (2) 359-366 [2014-03-01; online 2014-03-20]
Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
Antibody performance in western blot applications is context-dependent.
Algenäs C, Agaton C, Fagerberg L, ..., Ottosson Takanen J, Hober S
Biotechnol J 9 (3) 435-445 [2014-03-00; online 2014-01-10]
Spatial Proteomics Tissue Profiling
DOI Crossref
Analysis of plasma from prostate cancer patients links decreased carnosine dipeptidase 1 levels to lymph node metastasis
Qundos U, Johannesson H, Fredolini C, ..., Nilsson P, Schwenk JM
Translational Proteomics 2 (-) 14-24 [2014-03-00; online 2014-03-00]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics.
Fagerberg L, Hallström BM, Oksvold P, ..., Ponten F, Uhlén M
Mol. Cell Proteomics 13 (2) 397-406 [2014-02-00; online 2013-12-07]
Affinity Proteomics Stockholm [Technology development] Autoimmunity and Serology Profiling [Technology development] NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics Tissue Profiling
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Genome-scale metabolic modelling of hepatocytes reveals serine deficiency in patients with non-alcoholic fatty liver disease.
Mardinoglu A, Agren R, Kampf C, ..., Uhlen M, Nielsen J
Nat Commun 5 (-) 3083 [2014-01-15; online 2014-01-15]
Tissue Profiling
PubMed DOI Crossref
A systematic analysis of commonly used antibodies in cancer diagnostics.
Gremel G, Bergman J, Djureinovic D, ..., Micke P, Pontén F
Histopathology 64 (2) 293-305 [2014-01-00; online 2013-12-18]
Tissue Profiling
PubMed DOI Crossref
Profiling post-centrifugation delay of serum and plasma with antibody bead arrays.
Qundos U, Hong M, Tybring G, ..., Nilsson P, Schwenk JM
J Proteomics 95 (-) 46-54 [2013-12-16; online 2013-05-02]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Selectivity analysis of single binder assays used in plasma protein profiling.
Neiman M, Fredolini C, Johansson H, ..., Nilsson P, Schwenk JM
Proteomics 13 (23-24) 3406-3410 [2013-12-00; online 2013-10-24]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Using transcriptomics to improve butanol tolerance of Synechocystis sp. strain PCC 6803.
Anfelt J, Hallström B, Nielsen J, Uhlén M, Hudson EP
Appl. Environ. Microbiol. 79 (23) 7419-7427 [2013-12-00; online 2013-09-24]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion.
Gardberg M, Kaipio K, Lehtinen L, ..., Koivisto M, Carpén O
PLoS ONE 8 (9) e74923 [2013-09-26; online 2013-09-26]
Tissue Profiling
PubMed DOI Crossref
Autoantibody profiling in multiple sclerosis using arrays of human protein fragments.
Ayoglu B, Häggmark A, Khademi M, ..., Schwenk JM, Nilsson P
Mol. Cell Proteomics 12 (9) 2657-2672 [2013-09-00; online 2013-06-05]
Autoimmunity and Serology Profiling [Technology development]
PubMed DOI Crossref
Antibody-based profiling of cerebrospinal fluid within multiple sclerosis.
Häggmark A, Byström S, Ayoglu B, ..., Schwenk JM, Nilsson P
Proteomics 13 (15) 2256-2267 [2013-08-00; online 2013-05-23]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer.
Cepeda D, Ng HF, Sharifi HR, ..., Larsson LG, Sangfelt O
EMBO Mol Med 5 (7) 1067-1086 [2013-07-00; online 2013-06-19]
Tissue Profiling
PubMed DOI Crossref
Contribution of antibody-based protein profiling to the human Chromosome-centric Proteome Project (C-HPP).
Fagerberg L, Oksvold P, Skogs M, ..., von Feilitzen K, Uhlén M
J. Proteome Res. 12 (6) 2439-2448 [2013-06-07; online 2013-01-02]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse.
Geiger T, Velic A, Macek B, ..., Cox J, Mann M
Mol. Cell Proteomics 12 (6) 1709-1722 [2013-06-00; online 2013-02-26]
Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
A texture based pattern recognition approach to distinguish melanoma from non-melanoma cells in histopathological tissue microarray sections.
Rexhepaj E, Agnarsdóttir M, Bergman J, ..., Lundberg E, Ponten F
PLoS ONE 8 (5) e62070 [2013-05-17; online 2013-05-17]
Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
Majority of differentially expressed genes are down-regulated during malignant transformation in a four-stage model.
Danielsson F, Skogs M, Huss M, ..., Uhlén M, Lundberg E
Proc. Natl. Acad. Sci. U.S.A. 110 (17) 6853-6858 [2013-04-23; online 2013-04-10]
Spatial Proteomics
PubMed DOI Crossref
Systematic antibody generation and validation via tissue microarray technology leading to identification of a novel protein prognostic panel in breast cancer.
O Leary PC, Penny SA, Dolan RT, ..., Jirström K, Gallagher WM
BMC Cancer 13 (-) 175 [2013-04-02; online 2013-04-02]
Tissue Profiling
PubMed DOI Crossref
Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells.
Stadler C, Rexhepaj E, Singan VR, ..., Simpson JC, Lundberg E
Nat. Methods 10 (4) 315-323 [2013-04-00; online 2013-02-26]
Spatial Proteomics
PubMed DOI Crossref
Integration of clinical data with a genome-scale metabolic model of the human adipocyte.
Mardinoglu A, Agren R, Kampf C, ..., Uhlen M, Nielsen J
Mol. Syst. Biol. 9 (-) 649 [2013-03-21; online 2013-03-21]
Tissue Profiling
PubMed DOI Crossref
A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17.
Liu S, Im H, Bairoch A, ..., Beavis RC, Hancock WS
J. Proteome Res. 12 (1) 45-57 [2013-01-04; online 2012-12-25]
Spatial Proteomics
PubMed DOI Crossref
RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins.
Danielsson F, Wiking M, Mahdessian D, ..., Uhlén M, Lundberg E
J. Proteome Res. 12 (1) 299-307 [2013-01-04; online 2012-12-12]
Spatial Proteomics
PubMed DOI Crossref
High-resolution mapping of linear antibody epitopes using ultrahigh-density peptide microarrays.
Buus S, Rockberg J, Forsström B, ..., Uhlen M, Schafer-Nielsen C
Mol. Cell Proteomics 11 (12) 1790-1800 [2012-12-00; online 2012-09-18]
Autoimmunity and Serology Profiling [Service]
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Automated analysis and reannotation of subcellular locations in confocal images from the Human Protein Atlas.
Li J, Newberg JY, Uhlén M, Lundberg E, Murphy RF
PLoS ONE 7 (11) e50514 [2012-11-30; online 2012-11-30]
Spatial Proteomics
PubMed DOI Crossref
Comprehensive analysis of the genome transcriptome and proteome landscapes of three tumor cell lines.
Akan P, Alexeyenko A, Costea PI, ..., Uhlén M, Lundeberg J
Genome Med 4 (11) 86 [2012-11-18; online 2012-11-18]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics
PubMed DOI Crossref
A comprehensive comparison of RNA-Seq-based transcriptome analysis from reads to differential gene expression and cross-comparison with microarrays: a case study in Saccharomyces cerevisiae.
Nookaew I, Papini M, Pornputtapong N, ..., Uhlén M, Nielsen J
Nucleic Acids Res. 40 (20) 10084-10097 [2012-11-01; online 2012-09-12]
Bioinformatics Support and Infrastructure Bioinformatics Support, Infrastructure and Training NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
Secretagogin is expressed in sensory CGRP neurons and in spinal cord of mouse and complements other calcium-binding proteins, with a note on rat and human.
Shi TJ, Xiang Q, Zhang MD, ..., Harkany T, Hökfelt T
Mol Pain 8 (-) 80 [2012-10-29; online 2012-10-29]
Fluorescence Tissue Profiling
PubMed DOI Crossref
Scheffersomyces stipitis: a comparative systems biology study with the Crabtree positive yeast Saccharomyces cerevisiae.
Papini M, Nookaew I, Uhlén M, Nielsen J
Microb. Cell Fact. 11 (-) 136 [2012-10-09; online 2012-10-09]
Bioinformatics Support and Infrastructure Bioinformatics Support, Infrastructure and Training NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
Proteomic analysis reveals drug accessible cell surface N-glycoproteins of primary and established glioblastoma cell lines.
Bock T, Moest H, Omasits U, ..., Frei K, Wollscheid B
J. Proteome Res. 11 (10) 4885-4893 [2012-10-05; online 2012-08-23]
Spatial Proteomics
PubMed DOI Crossref
Multiplex epitope mapping using bacterial surface display reveals both linear and conformational epitopes.
Hudson EP, Uhlen M, Rockberg J
Sci Rep 2 (-) 706 [2012-10-04; online 2012-10-04]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
A tool to facilitate clinical biomarker studies--a tissue dictionary based on the Human Protein Atlas.
Kampf C, Bergman J, Oksvold P, ..., Uhlén M, Ponten F
BMC Med 10 (-) 103 [2012-09-12; online 2012-09-12]
Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
Validation of affinity reagents using antigen microarrays.
Sjöberg R, Sundberg M, Gundberg A, ..., Uhlén M, Nilsson P
N Biotechnol 29 (5) 555-563 [2012-06-15; online 2011-12-03]
Autoimmunity and Serology Profiling [Technology development]
PubMed DOI Crossref
Classification of protein profiles from antibody microarrays using heat and detergent treatment.
Häggmark A, Neiman M, Drobin K, ..., Nilsson P, Schwenk JM
N Biotechnol 29 (5) 564-570 [2012-06-15; online 2011-10-26]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy.
Stadler C, Hjelmare M, Neumann B, ..., Uhlén M, Lundberg E
J Proteomics 75 (7) 2236-2251 [2012-04-03; online 2012-03-01]
Spatial Proteomics
PubMed DOI Crossref
Antibody-based protein profiling of the human chromosome 21.
Uhlén M, Oksvold P, Älgenäs C, ..., Kondo T, Sivertsson Å
Mol. Cell Proteomics 11 (3) M111.013458 [2012-03-00; online 2011-11-02]
Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
A Protein Epitope Signature Tag (PrEST) library allows SILAC-based absolute quantification and multiplexed determination of protein copy numbers in cell lines.
Zeiler M, Straube WL, Lundberg E, Uhlen M, Mann M
Mol. Cell Proteomics 11 (3) O111.009613 [2012-03-00; online 2011-10-04]
Spatial Proteomics
PubMed DOI Crossref
Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization.
Ahmad Y, Boisvert FM, Lundberg E, Uhlen M, Lamond AI
Mol. Cell Proteomics 11 (3) M111.013680 [2012-03-00; online 2011-10-18]
Spatial Proteomics
PubMed DOI Crossref
Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
Larance M, Kirkwood KJ, Xirodimas DP, ..., Uhlen M, Lamond AI
Mol. Cell Proteomics 11 (3) M111.014407 [2012-03-00; online 2011-10-29]
Spatial Proteomics
PubMed DOI Crossref
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Hjelm B, Brennan DJ, Zendehrokh N, ..., Jirström K, Uhlen M
Proteomics Clin Appl 5 (11-12) 624-635 [2011-12-00; online 2011-10-01]
Tissue Profiling
PubMed DOI Crossref
Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model.
Kato BS, Nicholson G, Neiman M, ..., Spector TD, Schwenk JM
Proteome Sci 9 (-) 73 [2011-11-17; online 2011-11-17]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Plasma profiling reveals human fibulin-1 as candidate marker for renal impairment.
Neiman M, Hedberg JJ, Dönnes PR, ..., Schwenk JM, Nilsson P
J. Proteome Res. 10 (11) 4925-4934 [2011-11-04; online 2011-09-29]
Affinity Proteomics Stockholm [Collaborative]
PubMed DOI Crossref
Hypothalamic mitochondrial dysfunction associated with anorexia in the anx/anx mouse.
Lindfors C, Nilsson IA, Garcia-Roves PM, ..., Schalling M, Johansen JE
Proc. Natl. Acad. Sci. U.S.A. 108 (44) 18108-18113 [2011-11-01; online 2011-10-26]
Fluorescence Tissue Profiling
PubMed DOI Crossref
Generation of monospecific antibodies based on affinity capture of polyclonal antibodies.
Hjelm B, Forsström B, Igel U, ..., Johansson C, Uhlén M
Protein Sci. 20 (11) 1824-1835 [2011-11-00; online 2011-09-08]
Affinity Proteomics Stockholm [Technology development] Autoimmunity and Serology Profiling [Technology development] Spatial Proteomics
PubMed DOI Crossref
High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.
Jonsson L, Gaber A, Ulmert D, ..., Bjartell A, Jirström K
Diagn Pathol 6 (-) 91 [2011-09-28; online 2011-09-28]
Tissue Profiling
PubMed DOI Crossref
Large-scale protein profiling in human cell lines using antibody-based proteomics.
Fagerberg L, Strömberg S, El-Obeid A, ..., Ponten F, Asplund A
J. Proteome Res. 10 (9) 4066-4075 [2011-09-02; online 2011-07-06]
Tissue Profiling
PubMed DOI Crossref
Mapping the subcellular protein distribution in three human cell lines.
Fagerberg L, Stadler C, Skogs M, ..., Uhlén M, Lundberg E
J. Proteome Res. 10 (8) 3766-3777 [2011-08-05; online 2011-06-17]
Spatial Proteomics
PubMed DOI Crossref
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.
Ehlén Å, Nodin B, Rexhepaj E, ..., Brennan DJ, Jirström K
Transl Oncol 4 (4) 212-221 [2011-08-00; online 2011-08-01]
Tissue Profiling
PubMed DOI Crossref
Low RBM3 protein expression correlates with tumour progression and poor prognosis in malignant melanoma: an analysis of 215 cases from the Malmö Diet and Cancer Study.
Jonsson L, Bergman J, Nodin B, ..., Uhlén M, Jirström K
J Transl Med 9 (-) 114 [2011-07-21; online 2011-07-21]
Tissue Profiling
PubMed DOI Crossref
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Magnusson K, de Wit M, Brennan DJ, ..., Jirström K, Pontén F
Am. J. Surg. Pathol. 35 (7) 937-948 [2011-07-00; online 2011-06-17]
Spatial Proteomics Tissue Profiling
PubMed DOI Crossref
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
Jakobsen L, Vanselow K, Skogs M, ..., Hyman AA, Andersen JS
EMBO J. 30 (8) 1520-1535 [2011-04-20; online 2011-03-15]
Spatial Proteomics
PubMed DOI Crossref
Systematic antibody and antigen-based proteomic profiling with microarrays.
Ayoglu B, Häggmark A, Neiman M, ..., Schwenk JM, Nilsson P
Expert Rev. Mol. Diagn. 11 (2) 219-234 [2011-03-00; online 2011-03-17]
Affinity Proteomics Stockholm [Technology development] Autoimmunity and Serology Profiling [Technology development]
PubMed DOI Crossref
Tumor-specific HMG-CoA reductase expression in primary premenopausal breast cancer predicts response to tamoxifen.
Brennan DJ, Laursen H, O'Connor DP, ..., Rydén L, Jirström K
Breast Cancer Res. 13 (1) R12 [2011-01-31; online 2011-01-31]
Tissue Profiling
PubMed DOI Crossref
Defining the transcriptome and proteome in three functionally different human cell lines.
Lundberg E, Fagerberg L, Klevebring D, ..., Mann M, Uhlen M
Mol. Syst. Biol. 6 (-) 450 [2010-12-21; online 2010-12-24]
NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure Spatial Proteomics
PubMed DOI Crossref
Analysis of transcript and protein overlap in a human osteosarcoma cell line.
Klevebring D, Fagerberg L, Lundberg E, ..., Uhlén M, Lundeberg J
BMC Genomics 11 (-) 684 [2010-12-02; online 2010-12-02]
NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure Spatial Proteomics
PubMed DOI Crossref
SOX10 expression in superficial spreading and nodular malignant melanomas.
Agnarsdóttir M, Sooman L, Bolander A, ..., Uhlen M, Hedstrand H
Melanoma Res. 20 (6) 468-478 [2010-12-00; online 2010-10-05]
Tissue Profiling
PubMed DOI Crossref
Towards a knowledge-based Human Protein Atlas.
Uhlen M, Oksvold P, Fagerberg L, ..., Björling L, Ponten F
Nat. Biotechnol. 28 (12) 1248-1250 [2010-12-00; online 2010-12-09]
Spatial Proteomics
PubMed DOI Crossref
Creation of an antibody-based subcellular protein atlas.
Lundberg E, Uhlén M
Proteomics 10 (22) 3984-3996 [2010-11-00; online 2010-07-22]
Spatial Proteomics
PubMed DOI Crossref
Toward next generation plasma profiling via heat-induced epitope retrieval and array-based assays.
Schwenk JM, Igel U, Neiman M, ..., Nilsson P, Uhlen M
Mol. Cell Proteomics 9 (11) 2497-2507 [2010-11-00; online 2010-08-05]
Affinity Proteomics Stockholm [Technology development]
PubMed DOI Crossref
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer.
Ehlén A, Brennan DJ, Nodin B, ..., Pontén F, Jirström K
J Transl Med 8 (-) 78 [2010-08-20; online 2010-08-20]
Tissue Profiling
PubMed
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Lindskog C, Asplund A, Engkvist M, ..., Korsgren O, Ponten F
Discov Med 9 (49) 565-578 [2010-06-00; online 2010-07-01]
Tissue Profiling
PubMed DOI Crossref
A single fixation protocol for proteome-wide immunofluorescence localization studies.
Stadler C, Skogs M, Brismar H, Uhlén M, Lundberg E
J Proteomics 73 (6) 1067-1078 [2010-04-18; online 2009-11-10]
Spatial Proteomics
PubMed DOI Crossref
Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
Brennan DJ, Brändstedt J, Rexhepaj E, ..., O'Herlihy C, Jirstrom K
BMC Cancer 10 (-) 125 [2010-04-01; online 2010-04-01]
Tissue Profiling
PubMed
Molecular profiling using tissue microarrays as a tool to identify predictive biomarkers in laryngeal cancer treated with radiotherapy.
Holgersson G, Ekman S, Reizenstein J, ..., Hellström K, Bergström S
Cancer Genomics Proteomics 7 (1) 1-7 [2010-02-26; online 2010-02-26]
Tissue Profiling
PubMed DOI Crossref
Comparative protein profiling of serum and plasma using an antibody suspension bead array approach.
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