Heldin CH

The transcription factor LHX2 mediates and enhances oncogenic BMP signaling in medulloblastoma.

Ohata Y, Ali MM, Tsubakihara Y, ..., Swartling FJ, Moustakas A

Cell Death Differ. - (-) - [2025-03-28; online 2025-03-28]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells.

Tsirigoti C, Ali MM, Maturi V, Heldin CH, Moustakas A

Cell Death Dis 13 (9) 832 [2022-09-28; online 2022-09-28]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

TGFβ selects for pro-stemness over pro-invasive phenotypes during cancer cell epithelial-mesenchymal transition.

Tsubakihara Y, Ohata Y, Okita Y, ..., Heldin CH, Moustakas A

Mol Oncol 16 (12) 2330-2354 [2022-06-00; online 2022-04-10]

Bioinformatics Support for Computational Resources [Service]

BMP signaling is a therapeutic target in ovarian cancer.

Fukuda T, Fukuda R, Tanabe R, ..., Miyazono K, Heldin CH

Cell Death Discov 6 (1) 139 [2020-12-05; online 2020-12-05]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

The ALK-1/SMAD/ATOH8 axis attenuates hypoxic responses and protects against the development of pulmonary arterial hypertension.

Morikawa M, Mitani Y, Holmborn K, ..., Heldin CH, Miyazono K

Sci Signal 12 (607) eaay4430 [2019-11-12; online 2019-11-12]

Genome Engineering Zebrafish [Collaborative]