Jafari R

SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.

Murga M, Lopez-Pernas G, Soliva R, ..., Orozco M, Fernández-Capetillo O

Cell Death Dis 15 (9) 694 [2024-09-28; online 2024-09-28]

Chemical Biology Consortium Sweden [Collaborative] Global Proteomics and Proteogenomics [Service]

Prediction model for drug response of acute myeloid leukemia patients.

Trac QT, Pawitan Y, Mou T, ..., Kallioniemi O, Vu TN

NPJ Precis Oncol 7 (1) 32 [2023-03-24; online 2023-03-24]

Bioinformatics Support for Computational Resources [Service]

Proteogenomics refines the molecular classification of chronic lymphocytic leukemia

Herbst SA, Vesterlund M, Helmboldt AJ, ..., Lehtiö J, Dietrich S

Nat Commun 13 (1) 6226 [2022-10-20; online 2022-10-20]

Global Proteomics and Proteogenomics [Technology development]

Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.

Leo IR, Aswad L, Stahl M, ..., Vesterlund M, Jafari R

Nat Commun 13 (1) 1691 [2022-03-30; online 2022-03-30]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound.

Giovannucci TA, Salomons FA, Haraldsson M, ..., Johnsen JI, Dantuma NP

Cell Death Dis 12 (10) 914 [2021-10-06; online 2021-10-06]

CRISPR Functional Genomics [Service] Chemical Biology Consortium Sweden [Collaborative] Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Thermal proteome profiling identifies PIP4K2A and ZADH2 as off-targets of Polo-like kinase 1 inhibitor volasertib.

Goroshchuk O, Kolosenko I, Kunold E, ..., Jafari R, Palm-Apergi C

FASEB J. 35 (7) e21741 [2021-07-00; online 2021-06-19]

Global Proteomics and Proteogenomics [Service]

Novel Broad-Spectrum Antiviral Inhibitors Targeting Host Factors Essential for Replication of Pathogenic RNA Viruses.

Tampere M, Pettke A, Salata C, ..., Jafari R, Puumalainen MR

Viruses 12 (12) 1423 [2020-12-10; online 2020-12-10]

Global Proteomics and Proteogenomics [Service]

Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia.

Yang M, Vesterlund M, Siavelis I, ..., Lehtiö J, Paulsson K

Nat Commun 10 (1) 1519 [2019-04-03; online 2019-04-03]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics [Service] Clinical Genomics Lund [Service] Global Proteomics and Proteogenomics [Technology development]