Clinical Genomics Lund (25 publications)

Publications

SciLifeLab Infrastructure Unit Since 2016.

Started: 2016

Ended: Current

25 publications

Year 2020

A dynamic mutational landscape associated with an inter-regionally diverse immune response in malignant rhabdoid tumour.

Yasui H, Valind A, Karlsson J, ..., Backman T, Gisselsson D

J. Pathol. 252 (1) 22-28 [2020-09-00; online 2020-07-22]

Clinical Genomics Lund

PubMed DOI Crossref

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking.

Yang M, Safavi S, Woodward EL, ..., Nord KH, Paulsson K

Blood 136 (8) 946-956 [2020-08-20; online 2020-05-10]

Clinical Genomics Lund

PubMed DOI Crossref

Multiplex profiling of serum proteins in solution using barcoded antibody fragments and next generation sequencing.

Brofelth M, Ekstrand AI, Gour S, ..., Axelsson U, Borrebaeck CAK

Commun Biol 3 (1) 339 [2020-07-03; online 2020-07-03]

Clinical Genomics Lund

PubMed DOI Crossref

Recurrent Fusions Between YAP1 and KMT2A in Morphologically Distinct Neoplasms Within the Spectrum of Low-grade Fibromyxoid Sarcoma and Sclerosing Epithelioid Fibrosarcoma.

Puls F, Agaimy A, Flucke U, ..., Arbajian E, Mertens F

Am. J. Surg. Pathol. 44 (5) 594-606 [2020-05-00; online 2020-01-09]

Bioinformatics Compute and Storage [Service] Clinical Genomics Lund [Service]

PubMed DOI Crossref

Clonal competition within complex evolutionary hierarchies shapes AML over time.

Sandén C, Lilljebjörn H, Orsmark Pietras C, ..., Ågerstam H, Fioretos T

Nat Commun 11 (1) 579 [2020-02-05; online 2020-02-05]

Clinical Genomics Lund

PubMed DOI Crossref

Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development.

Köster J, Arbajian E, Viklund B, ..., Mandahl N, Mertens F

Cancer Genet 241 (-) 34-41 [2020-02-00; online 2019-12-10]

Bioinformatics Compute and Storage [Service] Clinical Genomics Lund

Year 2019

PubMed DOI Crossref

Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia

Yang M, Vesterlund M, Siavelis I, ..., Lehtiö J, Paulsson K

Nat Commun 10 (1) - [2019-12-00; online 2019-04-03]

Bioinformatics Compute and Storage [Service] Clinical Genomics Lund [Service] Global Proteomics and Proteogenomics [Technology development]

PubMed DOI Crossref

Undifferentiated pleomorphic sarcomas with PRDM10 fusions have a distinct gene expression profile.

Hofvander J, Puls F, Pillay N, ..., Nilsson J, Mertens F

J. Pathol. 249 (4) 425-434 [2019-12-00; online 2019-08-27]

Bioinformatics Compute and Storage [Service] Clinical Genomics Lund [Service]

DOI Crossref

FLT3N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

Hyrenius-Wittsten A, Pilheden M, Falqués-Costa A, ..., Järås M, Hagström-Andersson AK

Leukemia 33 (9) 2310-2314 [2019-09-00; online 2019-04-05]

Clinical Genomics Lund [Service]

DOI Crossref

Early growth response 1 regulates hematopoietic support and proliferation in human primary bone marrow stromal cells

Li H, Lim HC, Zacharaki D, ..., Hansson J, Scheding S

Haematologica - (-) haematol.2019.216648 [2019-08-01; online 2019-08-01]

Clinical Genomics Lund [Service]

DOI Crossref

Gene fusion involving the insulin-like growth factor 1 receptor in an ALK-negative inflammatory myofibroblastic tumour

Piarulli G, Puls F, Wängberg B, ..., Arbajian E, Mertens F

Histopathology 74 (7) 1098-1102 [2019-06-00; online 2019-04-24]

Bioinformatics Compute and Storage [Service] Clinical Genomics Lund [Service]

DOI Crossref

A urinary extracellular vesicle microRNA biomarker discovery pipeline; from automated extracellular vesicle enrichment by acoustic trapping to microRNA sequencing

Ku A, Ravi N, Yang M, ..., Lilja H, Ceder Y

PLoS ONE 14 (5) e0217507 [2019-05-29; online 2019-05-29]

Clinical Genomics Lund [Service]

Year 2018

PubMed DOI Crossref

Transcriptional landscape of B cell precursor acute lymphoblastic leukemia based on an international study of 1,223 cases.

Li JF, Dai YT, Lilljebjörn H, ..., Chen SJ, Huang JY

Proc. Natl. Acad. Sci. U.S.A. 115 (50) E11711-E11720 [2018-12-11; online 2018-11-28]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Convergent evolution of 11p allelic loss in multifocal Wilms tumors arising in WT1 mutation carriers.

Valind A, Wessman S, Pal N, ..., Sandstedt B, Gisselsson D

Pediatr Blood Cancer 65 (11) e27301 [2018-11-00; online 2018-07-03]

Clinical Genomics Lund [Service]

DOI Crossref

Neuroblastoma with flat genomic profile: a question of representativity?

Valind A, Öra I, Mertens F, Gisselsson D

BMJ Case Reports - (-) bcr-2018-225568 [2018-09-08; online 2018-09-08]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Gastrointestinal microbiota contributes to the development of murine transfusion-related acute lung injury.

Kapur R, Kim M, Rebetz J, ..., Speck ER, Semple JW

Blood Adv 2 (13) 1651-1663 [2018-07-10; online 2018-07-12]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Microenvironmental control of breast cancer subtype elicited through paracrine platelet-derived growth factor-CC signaling.

Roswall P, Bocci M, Bartoschek M, ..., Eriksson U, Pietras K

Nat. Med. 24 (4) 463-473 [2018-05-00; online 2018-03-12]

Clinical Genomics Lund [Service]

DOI Crossref

Clinical Value of RNA Sequencing–Based Classifiers for Prediction of the Five Conventional Breast Cancer Biomarkers: A Report From the Population-Based Multicenter Sweden Cancerome Analysis Network—Breast Initiative

Brueffer C, Vallon-Christersson J, Grabau D, ..., Borg Å, Saal LH

JCO Precision Oncology - (2) 1-18 [2018-03-00; online 2018-03-00]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Minimizing inequality in access to precision medicine in breast cancer by real-time population-based molecular analysis in the SCAN-B initiative.

Rydén L, Loman N, Larsson C, ..., Saal LH, Borg Å

Br J Surg 105 (2) e158-e168 [2018-01-00; online 2018-01-18]

Bioinformatics Compute and Storage [Service] Clinical Genomics Lund [Collaborative]

Year 2017

PubMed DOI Crossref

Isolated myelosarcoma is characterized by recurrent NFE2 mutations and concurrent preleukemic clones in the bone marrow.

Lazarevic V, Orsmark-Pietras C, Lilljebjörn H, ..., Juliusson G, Fioretos T

Blood - (-) - [2017-11-30; online 2017-11-30]

Clinical Genomics Lund [Collaborative]

PubMed DOI Crossref

New oncogenic subtypes in pediatric B-cell precursor acute lymphoblastic leukemia.

Lilljebjörn H, Fioretos T

Blood 130 (12) 1395-1401 [2017-09-21; online 2017-08-04]

Clinical Genomics Lund [Collaborative]

PubMed DOI Crossref

Gene Expression Profiling of Large Cell Lung Cancer Links Transcriptional Phenotypes to the New Histological WHO 2015 Classification

Karlsson A, Brunnström H, Micke P, ..., Planck M, Staaf J

Journal of Thoracic Oncology 12 (8) 1257-1267 [2017-08-00; online 2017-08-00]

Clinical Genomics Lund [Service] Clinical Genomics Uppsala [Collaborative]

PubMed DOI Crossref

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.

Davies H, Glodzik D, Morganella S, ..., Stratton MR, Nik-Zainal S

Nat. Med. 23 (4) 517-525 [2017-04-00; online 2017-03-13]

Clinical Genomics Lund [Collaborative]

PubMed DOI Crossref

Identification of two distinct mesenchymal stromal cell populations in human malignant glioma.

Svensson A, Ramos-Moreno T, Eberstål S, Scheding S, Bengzon J

J. Neurooncol. 131 (2) 245-254 [2017-01-00; online 2016-10-18]

Clinical Genomics Lund [Service]

Year 2016

PubMed DOI Crossref

Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia.

Lilljebjörn H, Henningsson R, Hyrenius-Wittsten A, ..., Fontes M, Fioretos T

Nat Commun 7 (-) 11790 [2016-06-06; online 2016-06-06]

Clinical Genomics Lund [Collaborative]