Protein Science Facility (PSF)

SciLifeLab National facility since 2013.

96 publications

Year 2017

DOI Crossref
Structural basis for dolichylphosphate mannose biosynthesis
Gandini R, Reichenbach T, Tan TC, Divne C
Nat Commun 8 (1) - [2017-12-00; online 2017-07-25]
Protein Science Facility (PSF)
DOI Crossref
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yin Y, Morgunova E, ..., Vinson C, Taipale J
Science 356 (6337) eaaj2239 [2017-05-05; online 2017-05-04]
Protein Science Facility (PSF)
DOI Crossref
SnoN Stabilizes the SMAD3/SMAD4 Protein Complex
Walldén K, Nyman T, Hällberg BM
Sci Rep 7 (-) 46370 [2017-04-11; online 2017-04-11]
Protein Science Facility (PSF)
DOI Crossref
Small Molecule Microarray Based Discovery of PARP14 Inhibitors
Peng B, Thorsell AG, ..., Schüler H, Yao SQ
Angew. Chem. Int. Ed. 56 (1) 248-253 [2017-01-02; online 2016-12-05]
Protein Science Facility (PSF)

Year 2016

PubMed DOI Crossref
A ribonucleotide reductase inhibitor with deoxyribonucleoside-reversible cytotoxicity.
Crona M, Codó P, ..., Fernandes AP, Tholander F
Mol Oncol 10 (9) 1375-1386 [2016-11-00; online 2016-07-26]
Protein Science Facility (PSF)
PubMed DOI Crossref
NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.
Valerie NC, Hagenkort A, ..., Jemth AS, Helleday T
Cancer Res. 76 (18) 5501-5511 [2016-09-15; online 2016-08-16]
Protein Science Facility (PSF)
PubMed DOI Crossref
Kinetic investigation of human 5-lipoxygenase with arachidonic acid.
Mittal M, Kumar RB, ..., Haeggström JZ, Rinaldo-Matthis A
Bioorg. Med. Chem. Lett. 26 (15) 3547-3551 [2016-08-01; online 2016-06-11]
Protein Science Facility (PSF)
PubMed DOI Crossref
Divergent non-heme iron enzymes in the nogalamycin biosynthetic pathway.
Siitonen V, Selvaraj B, ..., Schneider G, Metsä-Ketelä M
Proc. Natl. Acad. Sci. U.S.A. 113 (19) 5251-5256 [2016-05-10; online 2016-04-25]
Protein Science Facility (PSF)
PubMed DOI Crossref
A saposin-lipoprotein nanoparticle system for membrane proteins.
Frauenfeld J, Löving R, ..., Cheng Y, Nordlund P
Nat. Methods 13 (4) 345-351 [2016-04-00; online 2016-03-07]
Protein Science Facility (PSF)

Year 2015

PubMed DOI Crossref
Exploring water as building bricks in enzyme engineering.
Hendil-Forssell P, Martinelle M, Syrén PO
Chem. Commun. (Camb.) 51 (97) 17221-17224 [2015-12-18; online 2015-10-02]
Protein Science Facility (PSF)
DOI Crossref
Acid-Base Catalyst Discriminates between a Fructose 6-Phosphate Aldolase and a Transaldolase
Stellmacher L, Sandalova T, ..., Sprenger GA, Samland AK
ChemCatChem 7 (19) 3140-3151 [2015-10-00; online 2015-08-06]
Protein Science Facility (PSF)
PubMed DOI Crossref
Trimeric microsomal glutathione transferase 2 displays one third of the sites reactivity.
Ahmad S, Thulasingam M, ..., Haeggström JZ, Rinaldo-Matthis A
Biochim. Biophys. Acta 1854 (10 Pt A) 1365-1371 [2015-10-00; online 2015-06-13]
Protein Science Facility (PSF)
PubMed DOI Crossref
Structural Basis for the Specificity of Human NUDT16 and Its Regulation by Inosine Monophosphate.
Trésaugues L, Lundbäck T, ..., Gräslund S, Nordlund P
PLoS ONE 10 (6) e0131507 [2015-06-29; online 2015-06-29]
Protein Science Facility (PSF)

Year 2014

PubMed DOI Crossref
Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A.
Löw C, Quistgaard EM, ..., Balbach J, Nordlund P
Biol. Chem. 395 (7-8) 881-889 [2014-07-00; online 2014-07-09]
Protein Science Facility (PSF)
PubMed DOI Crossref
Structure and inhibition of mouse leukotriene C4 synthase.
Niegowski D, Kleinschmidt T, ..., Rinaldo-Matthis A, Haeggström JZ
PLoS ONE 9 (5) e96763 [2014-05-08; online 2014-05-08]
Chemical Biology Consortium Sweden (CBCS) Protein Science Facility (PSF)
PubMed DOI Crossref
Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms.
Raposo B, Dobritzsch D, ..., Schneider G, Holmdahl R
J. Exp. Med. 211 (3) 405-411 [2014-03-10; online 2014-02-19]
Protein Science Facility (PSF)
PubMed DOI Crossref
ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics.
Marteyn BS, Karimova G, ..., Sansonetti PJ, Tang CM
MBio 5 (2) e00022-e00014 [2014-03-04; online 2014-03-04]
Protein Science Facility (PSF)
PubMed DOI Crossref
Product formation controlled by substrate dynamics in leukotriene A4 hydrolase.
Stsiapanava A, Tholander F, ..., Haeggström JZ, Rinaldo-Matthis A
Biochim. Biophys. Acta 1844 (2) 439-446 [2014-02-00; online 2013-12-18]
Protein Science Facility (PSF)

Year 2013

PubMed DOI Crossref
Substrate specificity and oligomerization of human GMP synthetase.
Welin M, Lehtiö L, ..., Gräslund S, Nordlund P
J. Mol. Biol. 425 (22) 4323-4333 [2013-11-15; online 2013-07-03]
Protein Science Facility (PSF)
PubMed DOI Crossref
Nanobody mediated crystallization of an archeal mechanosensitive channel.
Löw C, Yau YH, ..., Steyaert J, Nordlund P
PLoS ONE 8 (10) e77984 [2013-10-21; online 2013-10-21]
Protein Science Facility (PSF)
PubMed DOI Crossref
PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.
Lindgren AE, Karlberg T, ..., Elofsson M, Schüler H
ACS Chem. Biol. 8 (8) 1698-1703 [2013-08-16; online 2013-06-08]
Protein Science Facility (PSF)
PubMed DOI Crossref
Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains.
Forst AH, Karlberg T, ..., Schüler H, Lüscher B
Structure 21 (3) 462-475 [2013-03-05; online 2013-03-12]
Protein Science Facility (PSF)

Year 2012