Cell Death Differ.

Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET.

Kanellis DC, Zisi A, Skrott Z, ..., Lindström MS, Bartek J

Cell Death Differ. 30 (7) 1666-1678 [2023-07-00; online 2023-05-04]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity.

Espinoza JA, Zisi A, Kanellis DC, ..., Lindström MS, Bartek J

Cell Death Differ. 27 (2) 773-789 [2020-02-00; online 2019-07-08]

Chemical Biology Consortium Sweden (CBCS) [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Fam83F induces p53 stabilisation and promotes its activity.

Salama M, Benitez-Riquelme D, Elabd S, ..., Davidson G, Blattner C

Cell Death Differ. 26 (10) 2125-2138 [2019-10-00; online 2019-01-28]

NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals.

Lans H, Lindvall JM, Thijssen K, ..., Nilsen H, Vermeulen W

Cell Death Differ. 20 (12) 1709-1718 [2013-12-00; online 2013-09-10]

Bioinformatics and Expression Analysis (BEA)

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis.

Nikulenkov F, Spinnler C, Li H, ..., Taipale J, Selivanova G

Cell Death Differ. 19 (12) 1992-2002 [2012-12-00; online 2012-07-14]

Karolinska High Throughput Center (KHTC)