Bexell D

Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma.

Karlsson J, Yasui H, Mañas A, ..., Bexell D, Gisselsson D

Nat Commun 15 (1) 8992 [2024-10-18; online 2024-10-18]

Clinical Genomics Lund [Service]

Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance.

Mañas A, Aaltonen K, Andersson N, ..., Gisselsson D, Bexell D

Sci Adv 8 (43) eabq4617 [2022-10-28; online 2022-10-28]

Clinical Genomics Lund [Service]

Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis.

Grigoryan A, Zacharaki D, Balhuizen A, ..., Bexell D, Bourgine PE

Sci Transl Med 14 (666) eabm6391 [2022-10-12; online 2022-10-12]

Clinical Genomics Lund [Service]

Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma.

Hansson K, Radke K, Aaltonen K, ..., Gisselsson D, Bexell D

Sci Transl Med 12 (562) - [2020-09-23; online 2020-09-25]

Clinical Genomics Lund [Service]

Integrative discovery of treatments for high-risk neuroblastoma.

Almstedt E, Elgendy R, Hekmati N, ..., Krona C, Nelander S

Nat Commun 11 (1) 71 [2020-01-03; online 2020-01-03]

Genome Engineering Zebrafish [Service]

Anti-tumor effects of PIM/PI3K/mTOR triple kinase inhibitor IBL-302 in neuroblastoma.

Mohlin S, Hansson K, Radke K, ..., von Stedingk K, Bexell D

EMBO Mol Med 11 (8) e10058 [2019-08-00; online 2019-07-16]

NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service] Structural Proteomics [Service]