Clinical Biomarkers

SciLifeLab Infrastructure Unit 2013–2020.

Started: 2013

Ended: 2020

119 publications

Year 2020

Identification of novel diagnostic and prognostic biomarkers for abdominal aortic aneurysm
Memon AA, Zarrouk M, Ågren-Witteschus S, ..., Gottsäter A, Sundquist K
Eur J Prev Cardiolog 27 (2) 132-142 [2020-01-00; online 2019-08-29]
Clinical Biomarkers [Service]

Year 2019

Cardiovascular organ damage in type 2 diabetes mellitus: the role of lipids and inflammation
Kozakova M, Morizzo C, Goncalves I, ..., Nilsson J, Palombo C
Cardiovasc Diabetol 18 (1) - [2019-12-00; online 2019-05-10]
Clinical Biomarkers [Service]
Viral antigens elicit augmented immune responses in primary Sjögren’s syndrome
Björk A, Thorlacius GE, Mofors J, ..., Kvarnström M, Wahren-Herlenius M
- - (-) - [2019-10-30; online 2019-10-30]
Clinical Biomarkers [Service]
Proteomic Analysis of Longitudinal Changes in Blood Pressure
Lin YT, Fall T, Hammar U, ..., Engström G, Sundström J
J Clin Med 8 (10) 1585 [2019-10-02; online 2019-10-02]
Clinical Biomarkers [Service]
Circulating mast cell progenitors correlate with reduced lung function in allergic asthma
Salomonsson M, Malinovschi A, Kalm‐Stephens P, ..., Alving K, Hallgren J
Clin Exp Allergy 49 (6) 874-882 [2019-06-00; online 2019-06-03]
Clinical Biomarkers [Service]
Increased vascular endothelial growth factor D is associated with atrial fibrillation and ischaemic stroke
Berntsson J, Smith JG, Johnson LSB, ..., Nilsson J, Engström G
Heart 105 (7) 553-558 [2019-04-00; online 2018-10-16]
Clinical Biomarkers [Service]
High Serum sCD40 and a Distinct Colonic T Cell Profile in Ulcerative Colitis Associated With Primary Sclerosing Cholangitis
Lampinen M, Vessby J, Fredricsson A, ..., Rorsman F, Carlson M
- 13 (3) 341-350 [2019-03-26; online 2018-10-20]
Clinical Biomarkers [Service]
Circulating proteins as predictors of cardiovascular mortality in end-stage renal disease
Feldreich T, Nowak C, Fall T, ..., Green D, Ärnlöv J
J Nephrol 32 (1) 111-119 [2019-02-00; online 2018-11-29]
Clinical Biomarkers [Service]
Plasma kidney injury molecule-1 (p-KIM-1) levels and deterioration of kidney function over 16 years
Schulz CA, Engström G, Nilsson J, ..., Melander O, Orho-Melander M
- - (-) - [2019-01-09; online 2019-01-09]
Clinical Biomarkers [Service]

Year 2018

Associations of Circulating Protein Levels With Lipid Fractions in the General Population
Figarska SM, Gustafsson S, Sundström J, ..., Lind L, Ingelsson E
Arterioscler Thromb Vasc Biol 38 (10) 2505-2518 [2018-10-00; online 2018-10-00]
Clinical Biomarkers [Service]
Plasma levels of the proprotein convertase furin and incidence of diabetes and mortality
Fernandez C, Rysä J, Almgren P, ..., Ruskoaho H, Melander O
J Intern Med 284 (4) 377-387 [2018-10-00; online 2018-07-02]
Clinical Biomarkers [Service]
FADD (Fas-Associated Protein With Death Domain), Caspase-3, and Caspase-8 and Incidence of Ischemic Stroke
Muhammad IF, Borné Y, Melander O, ..., Söderholm M, Engström G
Stroke 49 (9) 2224-2226 [2018-09-00; online 2018-09-00]
Clinical Biomarkers [Service]
Proteomic Biomarkers for Incident Aortic Stenosis Requiring Valvular Replacement
Ljungberg J, Janiec M, Bergdahl IA, ..., Fall T, Söderberg S
Circulation 138 (6) 590-599 [2018-08-07; online 2018-08-07]
Clinical Biomarkers [Service]
Identification of novel diagnostic biomarkers for deep venous thrombosis
Memon AA, Sundquist K, PirouziFard M, ..., Sundquist J, Zöller B
Br J Haematol 181 (3) 378-385 [2018-05-00; online 2018-04-19]
Clinical Biomarkers [Service]
Proteomic Profiling for Cardiovascular Biomarker Discovery in Orthostatic Hypotension
Johansson M, Ricci F, Aung N, ..., Melander O, Fedorowski A
Hypertension 71 (3) 465-472 [2018-03-00; online 2018-03-00]
Clinical Biomarkers [Service]
Galectin-3 levels relate in children to total body fat, abdominal fat, body fat distribution, and cardiac size
Dencker M, Arvidsson D, Karlsson MK, ..., Andersen LB, Thorsson O
Eur J Pediatr 177 (3) 461-467 [2018-03-00; online 2018-01-11]
Clinical Biomarkers [Service]

Year 2017

Targeted proteomic analysis of habitual coffee consumption.
Cornelis MC, Gustafsson S, Ärnlöv J, ..., Lind L, Ingelsson E
J. Intern. Med. - (-) - [2017-10-16; online 2017-10-16]
Clinical Biomarkers [Service]
Subphenotypes of inflammatory bowel disease are characterized by specific serum protein profiles
Andersson E, Bergemalm D, Kruse R, ..., Repsilber D, Halfvarson J
PLoS ONE 12 (10) e0186142 [2017-10-05; online 2017-10-05]
Clinical Biomarkers [Service]
Eosinophil Cationic Protein, Carotid Plaque, and Incidence of Stroke.
Sundström J, Söderholm M, Borné Y, ..., Orho-Melander M, Engström G
pii: STROKEAHA.117.018450
Stroke 48 (10) 2686-2692 [2017-10-00; online 2017-09-13]
Clinical Biomarkers [Service]
Tumor Necrosis Factor Receptor 1 and 2 Are Associated With Risk of Intracerebral Hemorrhage.
Svensson EH, Söderholm M, Abul-Kasim K, Engström G
pii: STROKEAHA.117.017849
Stroke 48 (10) 2710-2715 [2017-10-00; online 2017-08-22]
Clinical Biomarkers [Service]
Plasma stem cell factor levels are associated with risk of cardiovascular disease and death
Björkbacka H, Yao Mattisson I, Wigren M, ..., Engström G, Nilsson J
J Intern Med - (-) - [2017-09-21; online 2017-09-21]
Clinical Biomarkers [Service]
Effect of food intake on 92 neurological biomarkers in plasma
Dencker M, Björgell O, Hlebowicz J
Brain Behav 7 (9) e00747 [2017-09-00; online 2017-08-01]
Clinical Biomarkers [Service]
Use of Proteomics To Investigate Kidney Function Decline over 5 Years.
Carlsson AC, Ingelsson E, Sundström J, ..., Lind L, Ärnlöv J
pii: CJN.08780816 pmc: PMC5544512
Clin J Am Soc Nephrol 12 (8) 1226-1235 [2017-08-07; online 2017-07-21]
Clinical Biomarkers [Service]
Effect of food intake on 92 biomarkers for cardiovascular disease
Dencker M, Gårdinger Y, Björgell O, Hlebowicz J
PLoS ONE 12 (6) e0178656 [2017-06-06; online 2017-06-06]
Clinical Biomarkers [Service]
FADD, Caspase-3, and Caspase-8 and Incidence of Coronary Events.
Xue L, Borné Y, Mattisson IY, ..., Nilsson J, Engström G
pii: ATVBAHA.117.308995
Arterioscler. Thromb. Vasc. Biol. 37 (5) 983-989 [2017-05-00; online 2017-03-16]
Clinical Biomarkers [Service]
Discovery of new biomarkers for atrial fibrillation using a custom-made proteomics chip.
Lind L, Sundström J, Stenemo M, Hagström E, Ärnlöv J
pii: heartjnl-2016-309764
Heart 103 (5) 377-382 [2017-03-00; online 2016-09-10]
Clinical Biomarkers [Service]
Use of a proximity extension assay proteomics chip to discover new biomarkers associated with albuminuria.
Carlsson AC, Sundström J, Carrero JJ, ..., Lind L, Ärnlöv J
pii: 2047487316676134
Eur J Prev Cardiol 24 (4) 340-348 [2017-03-00; online 2016-10-28]
Clinical Biomarkers [Service]
Signs of ongoing inflammation in female patients with chronic widespread pain
Gerdle B, Ghafouri B, Ghafouri N, Bäckryd E, Gordh T
Medicine 96 (9) e6130 [2017-03-00; online 2017-03-00]
Clinical Biomarkers [Service]

Year 2016

DcR3, TFF3, and Midkine Are Novel Serum Biomarkers in Small Intestinal Neuroendocrine Tumors.
Edfeldt K, Daskalakis K, Bäcklin C, ..., Hellman P, Stålberg P
pii: 000452891
Neuroendocrinology 105 (2) 170-181 [2016-11-09; online 2016-11-09]
Clinical Biomarkers [Service]
Effects of cigarette smoking on cardiovascular-related protein profiles in two community-based cohort studies.
Huang B, Svensson P, Ärnlöv J, ..., Lind L, Ingelsson E
pii: S0021-9150(16)31328-4
Atherosclerosis 254 (-) 52-58 [2016-11-00; online 2016-09-30]
Clinical Biomarkers [Service]
Endarterectomy patients with elevated levels of circulating IL-16 have fewer cardiovascular events during follow-up.
Grönberg C, Asciutto G, Persson A, ..., Gonçalves I, Björkbacka H
pii: S1043-4666(16)30137-5
Cytokine 85 (-) 137-139 [2016-09-00; online 2016-06-28]
Clinical Biomarkers [Service]
Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients
Loskog A, Maleka A, Mangsbo S, ..., Tötterman TH, Ullenhag G
Br J Cancer 114 (8) 872-880 [2016-04-00; online 2016-03-31]
Clinical Biomarkers [Service]
Decreased levels of stem cell factor in subjects with incident coronary events.
Wigren M, Rattik S, Hultman K, ..., Gonçalves I, Nilsson J
J. Intern. Med. 279 (2) 180-191 [2016-02-00; online 2015-10-14]
Clinical Biomarkers [Service]
High levels of cathepsin D and cystatin B are associated with increased risk of coronary events
Gonçalves I, Hultman K, Dunér P, ..., Nilsson J, Bengtsson E
Open Heart 3 (1) e000353 [2016-01-00; online 2016-01-27]
Clinical Biomarkers [Service]
High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy
Edsfeldt A, Bengtsson E, Asciutto G, ..., Nilsson J, Goncalves I
Cerebrovasc Dis 41 (3-4) 199-203 [2016-00-00; online 2016-01-27]
Clinical Biomarkers [Service]

Year 2015

Protein profiling reveals consequences of lifestyle choices on predicted biological aging.
Enroth S, Enroth SB, Johansson Å, Gyllensten U
pii: srep17282 pmc: PMC4664859
Sci Rep 5 (-) 17282 [2015-12-01; online 2015-12-01]
Clinical Biomarkers
Associations between circulating proteins and corresponding genes expressed in coronary thrombi in patients with acute myocardial infarction.
Helseth R, Weiss TW, Opstad TB, ..., Arnesen H, Seljeflot S
pii: S0049-3848(15)30137-7
Thromb. Res. 136 (6) 1240-1244 [2015-12-00; online 2015-10-08]
Clinical Biomarkers [Service]
Discovery of New Risk Markers for Ischemic Stroke Using a Novel Targeted Proteomics Chip.
Lind L, Siegbahn A, Lindahl B, ..., Sundström J, Ärnlöv J
pii: STROKEAHA.115.010829
Stroke 46 (12) 3340-3347 [2015-12-00; online 2015-11-07]
Clinical Biomarkers
Fibroblast Growth Factor 23 and Incidence of Subarachnoid Hemorrhage: Nested Case-Control Study.
Söderholm M, Engström G
pii: STROKEAHA.115.010565
Stroke 46 (11) 3260-3262 [2015-11-00; online 2015-09-22]
Clinical Biomarkers [Service]
Use of a proximity extension assay proteomics chip to discover new biomarkers for human atherosclerosis.
Lind L, Ärnlöv J, Lindahl B, ..., Sundström J, Ingelsson E
pii: S0021-9150(15)30043-5
Atherosclerosis 242 (1) 205-210 [2015-09-00; online 2015-07-24]
Clinical Biomarkers
Low Elastin Content of Carotid Plaques Is Associated with Increased Risk of Ipsilateral Stroke
Asciutto G, Dias NV, Edsfeldt A, ..., Nilsson J, Gonçalves I
PLoS ONE 10 (3) e0121086 [2015-03-24; online 2015-03-24]
Clinical Biomarkers [Service]

Year 2014

Year 2013

Year 2012

Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease.
Gu GJ, Wu D, Lund H, ..., Landegren U, Kamali-Moghaddam M
pii: C06R73LN268U5222
J. Alzheimers Dis. 33 (3) 699-713 [2012-09-25; online 2012-09-25]
Clinical Biomarkers PLA and Single Cell Proteomics

Year 2011

Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer.
Tavoosidana G, Ronquist G, Darmanis S, ..., Landegren UD, Kamali-Moghaddam M
pii: 1019330108 pmc: PMC3102389
Proc. Natl. Acad. Sci. U.S.A. 108 (21) 8809-8814 [2011-05-24; online 2011-05-11]
Clinical Biomarkers PLA and Single Cell Proteomics