Lindström MS

Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling.

Wenson L, Heldin J, Martin M, ..., Spjuth O, Söderberg O

Nat Commun 16 (1) 7130 [2025-08-04; online 2025-08-04]

Bioinformatics Support, Infrastructure and Training [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET.

Kanellis DC, Zisi A, Skrott Z, ..., Lindström MS, Bartek J

Cell Death Differ. 30 (7) 1666-1678 [2023-07-00; online 2023-05-04]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Small molecule-mediated disruption of ribosome biogenesis synergizes with FGFR inhibitors to suppress glioma cell growth

Zisi A, Kanellis DC, Moussaud S, ..., Bartek J, Lindström MS

Neuro-oncology 25 (6) 1058-1072 [2023-06-02; online 2022-12-30]

Chemical Biology Consortium Sweden [Collaborative]

SFRP2 induces a mesenchymal subtype transition by suppression of SOX2 in glioblastoma.

Guo M, Goudarzi KM, Abedi S, ..., Nistér M, Hägerstrand D

Oncogene 40 (32) 5066-5080 [2021-08-00; online 2021-05-21]

Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

The exon-junction complex helicase eIF4A3 controls cell fate via coordinated regulation of ribosome biogenesis and translational output.

Kanellis DC, Espinoza JA, Zisi A, ..., Lindström MS, Bartek J

Sci Adv 7 (32) - [2021-08-00; online 2021-08-04]

Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.

Peuget S, Zhu J, Sanz G, ..., Zubarev R, Selivanova G

Cancer Res. 80 (7) 1538-1550 [2020-04-01; online 2020-02-04]

Chemical Proteomics [Collaborative]

The antimalarial drug amodiaquine stabilizes p53 through ribosome biogenesis stress, independently of its autophagy-inhibitory activity.

Espinoza JA, Zisi A, Kanellis DC, ..., Lindström MS, Bartek J

Cell Death Differ. 27 (2) 773-789 [2020-02-00; online 2019-07-08]

Chemical Biology Consortium Sweden [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]