Nat Commun

ISSN	2041-1723
ISSN-L	2041-1723
IUID	a574eb04884e4c0aaf82a210844daf7c
Modified	2020-11-27T13:14:08.691Z
Created	2017-05-09T09:12:08.433Z

PubMed DOI Crossref

Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM.

Valerie NCK, Sanjiv K, Mortusewicz O, ..., Page BDG, Altun M

Nat Commun 15 (1) 10347 [2024-12-06; online 2024-12-06]

Chemical Biology Consortium Sweden (CBCS) [Service]

PubMed DOI Crossref

A landscape of X-inactivation during human T cell development.

Gylemo B, Bensberg M, Hennings V, ..., Ekwall O, Nestor CE

Nat Commun 15 (1) 10527 [2024-12-04; online 2024-12-04]

Clinical Genomics Linköping [Service]

PubMed DOI Crossref

Streptolysin O accelerates the conversion of plasminogen to plasmin

Tang D, Khakzad H, Hjortswang E, ..., Happonen L, Malmström J

Nat Commun 15 (1) 10212 [2024-11-25; online 2024-11-25]

Structural Proteomics [Technology development]

PubMed DOI Crossref

Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters.

García Casas P, Rossini M, Påvénius L, ..., Pizzo P, Filadi R

Nat Commun 15 (1) 9775 [2024-11-12; online 2024-11-12]

Integrated Microscopy Technologies Stockholm [Collaborative]

PubMed DOI Crossref

A unique symbiosome in an anaerobic single-celled eukaryote.

Jerlström-Hultqvist J, Gallot-Lavallée L, Salas-Leiva DE, ..., Archibald JM, Roger AJ

Nat Commun 15 (1) 9726 [2024-11-09; online 2024-11-09]

Integrated Microscopy Technologies Umeå [Service]

PubMed DOI Crossref

Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy.

Forsthuber A, Aschenbrenner B, Korosec A, ..., Kasper M, Lichtenberger BM

Nat Commun 15 (1) 9678 [2024-11-08; online 2024-11-08]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

The structure and function of P5A-ATPases.

Li P, Bågenholm V, Hägglund P, ..., Wang K, Gourdon P

Nat Commun 15 (1) 9605 [2024-11-06; online 2024-11-06]

Cryo-EM [Service]

PubMed DOI Crossref

A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice.

Mebrahtu A, Laurén I, Veerman R, ..., Rockberg J, Mangsbo S

Nat Commun 15 (1) 9542 [2024-11-05; online 2024-11-05]

Affinity Proteomics Uppsala [Service] Drug Discovery and Development (DDD) [Service]

PubMed DOI Crossref

High-parametric protein maps reveal the spatial organization in early-developing human lung.

Sariyar S, Sountoulidis A, Hansen JN, ..., Lundberg E, Ayoglu B

Nat Commun 15 (1) 9381 [2024-10-30; online 2024-10-30]

BioImage Informatics [Service]

PubMed DOI Crossref

Integrative spatial and genomic analysis of tumor heterogeneity with Tumoroscope.

Shafighi S, Geras A, Jurzysta B, ..., Lagergren J, Szczurek E

Nat Commun 15 (1) 9343 [2024-10-29; online 2024-10-29]

NGI Other [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Epigenetic memory of radiotherapy in dermal fibroblasts impairs wound repair capacity in cancer survivors.

Bian X, Piipponen M, Liu Z, ..., Halle M, Xu Landén N

Nat Commun 15 (1) 9286 [2024-10-28; online 2024-10-28]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma.

Karlsson J, Yasui H, Mañas A, ..., Bexell D, Gisselsson D

Nat Commun 15 (1) 8992 [2024-10-18; online 2024-10-18]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19.

Jernbom AF, Skoglund L, Pin E, ..., Månberg A, Nilsson P

Nat Commun 15 (1) 8941 [2024-10-17; online 2024-10-17]

Autoimmunity and Serology Profiling [Collaborative]

PubMed DOI Crossref

Resilience of genetic diversity in forest trees over the Quaternary.

Milesi P, Kastally C, Dauphin B, ..., Pyhäjärvi T, GenTree Consortium

Nat Commun 15 (1) 8538 [2024-10-14; online 2024-10-14]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

De novo production of protoberberine and benzophenanthridine alkaloids through metabolic engineering of yeast.

Jiao X, Fu X, Li Q, ..., Nielsen J, Chen Y

Nat Commun 15 (1) 8759 [2024-10-09; online 2024-10-09]

Chalmers Mass Spectrometry Infrastructure [Collaborative] Integrated Microscopy Technologies Gothenburg [Service]

PubMed DOI Crossref

Unmasking AlphaFold to integrate experiments and predictions in multimeric complexes.

Mirabello C, Wallner B, Nystedt B, Azinas S, Carroni M

Nat Commun 15 (1) 8724 [2024-10-09; online 2024-10-09]

Bioinformatics Support, Infrastructure and Training [Technology development] Cryo-EM [Service]

PubMed DOI Crossref

The lncRNA SNHG26 drives the inflammatory-to-proliferative state transition of keratinocyte progenitor cells during wound healing.

Li D, Liu Z, Zhang L, ..., Sommar P, Xu Landén N

Nat Commun 15 (1) 8637 [2024-10-05; online 2024-10-05]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Single cell [Service] NGI Spatial omics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

The single-cell transcriptomic atlas iPain identifies senescence of nociceptors as a therapeutical target for chronic pain treatment.

Techameena P, Feng X, Zhang K, Hadjab S

Nat Commun 15 (1) 8585 [2024-10-04; online 2024-10-04]

Bioinformatics Support for Computational Resources [Service] NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.

Mantas I, Flais I, Masarapu Y, ..., Perlmann T, Svenningsson P

Nat Commun 15 (1) 8176 [2024-09-18; online 2024-09-18]

NGI Other [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets.

Su TY, Hauenstein J, Somuncular E, ..., Månsson R, Luc S

Nat Commun 15 (1) 7966 [2024-09-11; online 2024-09-11]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor.

Pandiloski N, Horváth V, Karlsson O, ..., Jakobsson J, Douse CH

Nat Commun 15 (1) 7534 [2024-08-30; online 2024-08-30]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Lund [Service] NGI Long read [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

An intronic copy number variation in Syntaxin 17 determines speed of greying and melanoma incidence in Grey horses.

Rubin CJ, Hodge M, Naboulsi R, ..., Lindgren G, Andersson L

Nat Commun 15 (1) 7510 [2024-08-29; online 2024-08-29]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Structural basis of frizzled 7 activation and allosteric regulation.

Bous J, Kinsolving J, Grätz L, ..., Adebali O, Schulte G

Nat Commun 15 (1) 7422 [2024-08-28; online 2024-08-28]

Cryo-EM [Service]

PubMed DOI Crossref

Single-cell transcriptomics reveal transcriptional programs underlying male and female cell fate during Plasmodium falciparum gametocytogenesis.

Mohammed M, Dziedziech A, Macedo D, ..., Henriksson J, Ankarklev J

Nat Commun 15 (1) 7177 [2024-08-26; online 2024-08-26]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

BaTwa populations from Zambia retain ancestry of past hunter-gatherer groups.

Breton G, Barham L, Mudenda G, ..., Schlebusch CM, Jakobsson M

Nat Commun 15 (1) 7307 [2024-08-24; online 2024-08-24]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Gothenburg [Collaborative] NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

FOXO-regulated OSER1 reduces oxidative stress and extends lifespan in multiple species.

Song J, Li Z, Zhou L, ..., Rasmussen LJ, Dai F

Nat Commun 15 (1) 7144 [2024-08-21; online 2024-08-21]

NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Host-pathogen interactions in the Plasmodium-infected mouse liver at spatial and single-cell resolution.

Hildebrandt F, Iturritza MU, Zwicker C, ..., Lundeberg J, Ankarklev J

Nat Commun 15 (1) 7105 [2024-08-19; online 2024-08-19]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Motor innervation directs the correct development of the mouse sympathetic nervous system.

Erickson AG, Motta A, Kastriti ME, ..., Bonanomi D, Adameyko I

Nat Commun 15 (1) 7065 [2024-08-16; online 2024-08-16]

Integrated Microscopy Technologies Stockholm [Collaborative]

PubMed DOI Crossref

Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins.

Unneberg P, Larsson M, Olsson A, ..., Meyer B, Wallberg A

Nat Commun 15 (1) 6297 [2024-08-01; online 2024-08-01]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Service]

PubMed DOI Crossref

A genetic-epigenetic interplay at 1q21.1 locus underlies CHD1L-mediated vulnerability to primary progressive multiple sclerosis.

Pahlevan Kakhki M, Giordano A, Starvaggi Cucuzza C, ..., Kular L, Jagodic M

Nat Commun 15 (1) 6419 [2024-07-30; online 2024-07-30]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Multi-compartmental diversification of neutralizing antibody lineages dissected in SARS-CoV-2 spike-immunized macaques.

Mandolesi M, Das H, de Vries L, ..., Murrell B, Karlsson Hedestam GB

Nat Commun 15 (1) 6338 [2024-07-27; online 2024-07-27]

Bioinformatics Support for Computational Resources [Service] NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Interneuron diversity in the human dorsal striatum.

Garma LD, Harder L, Barba-Reyes JM, ..., Hyman BT, Muñoz-Manchado AB

Nat Commun 15 (1) 6164 [2024-07-22; online 2024-07-22]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

A single-cell pan-cancer analysis to show the variability of tumor-infiltrating myeloid cells in immune checkpoint blockade.

Li W, Pan L, Hong W, ..., Xiao C, Li X

Nat Commun 15 (1) 6142 [2024-07-21; online 2024-07-21]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

The Escherichia coli chromosome moves to the replisome.

Gras K, Fange D, Elf J

Nat Commun 15 (1) 6018 [2024-07-17; online 2024-07-17]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Long-range charge transfer mechanism of the III2IV2 mycobacterial supercomplex.

Riepl D, Gamiz-Hernandez AP, Kovalova T, ..., Brzezinski P, Kaila VRI

Nat Commun 15 (1) 5276 [2024-06-20; online 2024-06-20]

Cryo-EM [Service]

PubMed DOI Crossref

descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques.

Otomo K, Omura T, Nozawa Y, ..., Brismar H, Susaki EA

Nat Commun 15 (1) 4941 [2024-06-12; online 2024-06-12]

Integrated Microscopy Technologies Stockholm [Technology development]

PubMed DOI Crossref

Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice.

Masarapu Y, Cekanaviciute E, Andrusivova Z, ..., Costes SV, Giacomello S

Nat Commun 15 (1) 4778 [2024-06-11; online 2024-06-11]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative]

PubMed DOI Crossref

ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.

Zhang Y, Xie G, Lee JE, ..., Ge K, Kutateladze TG

Nat Commun 15 (1) 4883 [2024-06-07; online 2024-06-07]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Structure and mechanism of the K+/H+ exchanger KefC.

Gulati A, Kokane S, Perez-Boerema A, ..., Matsuoka R, Drew D

Nat Commun 15 (1) 4751 [2024-06-04; online 2024-06-04]

Cryo-EM [Service]

PubMed DOI Crossref

Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers.

De Oliveira DH, Gowda V, Sparrman T, ..., Lendel C, Hedhammar M

Nat Commun 15 (1) 4670 [2024-05-31; online 2024-05-31]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Longitudinal molecular profiling elucidates immunometabolism dynamics in breast cancer.

Wang K, Zerdes I, Johansson HJ, ..., Matikas A, Foukakis T

Nat Commun 15 (1) 3837 [2024-05-07; online 2024-05-07]

Global Proteomics and Proteogenomics [Collaborative]

PubMed DOI Crossref

The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies.

Izadi A, Karami Y, Bratanis E, ..., Malmström L, Nordenfelt P

Nat Commun 15 (1) 3600 [2024-04-27; online 2024-04-27]

Drug Discovery and Development (DDD) [Service]

PubMed DOI Crossref

Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.

Papakyriacou I, Kutkaite G, Rúbies Bedós M, ..., Menden MP, Mao Y

Nat Commun 15 (1) 3581 [2024-04-27; online 2024-04-27]

Bioinformatics Support for Computational Resources [Service] CRISPR Functional Genomics [Service]

PubMed DOI Crossref

The gut commensal Blautia maintains colonic mucus function under low-fiber consumption through secretion of short-chain fatty acids.

Holmberg SM, Feeney RH, Prasoodanan P K V, ..., Skurk T, Schroeder BO

Nat Commun 15 (1) 3502 [2024-04-25; online 2024-04-25]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue.

Zhang N, Harbers L, Simonetti M, ..., Bienko M, Crosetto N

Nat Commun 15 (1) 3475 [2024-04-24; online 2024-04-24]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Molecular patterns of resistance to immune checkpoint blockade in melanoma.

Lauss M, Phung B, Borch TH, ..., Donia M, Jönsson G

Nat Commun 15 (1) 3075 [2024-04-09; online 2024-04-09]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.

Eisele AS, Tarbier M, Dormann AA, Pelechano V, Suter DM

Nat Commun 15 (1) 2744 [2024-03-29; online 2024-03-29]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.

Bechtella L, Chunsheng J, Fentker K, ..., Karlsson NG, Pagel K

Nat Commun 15 (1) 2611 [2024-03-23; online 2024-03-23]

Glycoproteomics and MS Proteomics [Collaborative]

PubMed DOI Crossref

Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner.

ElBeck Z, Hossain MB, Siga H, ..., Végvári Á, Betsholtz C

Nat Commun 15 (1) 2358 [2024-03-20; online 2024-03-20]

BioImage Informatics [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative]

PubMed DOI Crossref

fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles.

Dennhag N, Kahsay A, Nissen I, ..., von Hofsten J, Pedrosa Domellöf F

Nat Commun 15 (1) 1950 [2024-03-02; online 2024-03-02]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Prediction of plasma ctDNA fraction and prognostic implications of liquid biopsy in advanced prostate cancer.

Fonseca NM, Maurice-Dror C, Herberts C, ..., Chi KN, Wyatt AW

Nat Commun 15 (1) 1828 [2024-02-28; online 2024-02-28]

Clinical Genomics Stockholm [Service]

PubMed DOI Crossref

scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cells.

Chen JP, Diekmann C, Wu H, ..., Bienko M, Crosetto N

Nat Commun 15 (1) 1768 [2024-02-27; online 2024-02-27]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF.

Kvedaraite E, Lourda M, Mouratidou N, ..., Henter JI, Svensson M

Nat Commun 15 (1) 1752 [2024-02-26; online 2024-02-26]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

The role of extracellular vesicle fusion with target cells in triggering systemic inflammation.

Papareddy P, Tapken I, Kroh K, ..., Holub M, Herwald H

Nat Commun 15 (1) 1150 [2024-02-07; online 2024-02-07]

Glycoproteomics and MS Proteomics [Service]

PubMed DOI Crossref

Asymmetric nucleosome PARylation at DNA breaks mediates directional nucleosome sliding by ALC1.

Bacic L, Gaullier G, Mohapatra J, ..., Sabantsev A, Deindl S

Nat Commun 15 (1) 1000 [2024-02-02; online 2024-02-02]

Cryo-EM [Service]

PubMed DOI Crossref

A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection.

von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME

Nat Commun 15 (1) 904 [2024-01-30; online 2024-01-30]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.

Drexhage LZ, Zhang S, Dupont M, ..., Karaji N, Sattentau QJ

Nat Commun 15 (1) 541 [2024-01-15; online 2024-01-15]

Integrated Microscopy Technologies Stockholm [Service]

PubMed DOI Crossref

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence.

Kohler V, Kohler A, Berglund LL, ..., Andréasson C, Büttner S

Nat Commun 15 (1) 315 [2024-01-05; online 2024-01-05]

Global Proteomics and Proteogenomics [Service]

PubMed DOI Crossref

Blue-shift photoconversion of near-infrared fluorescent proteins for labeling and tracking in living cells and organisms.

Pennacchietti F, Alvelid J, Morales RA, ..., Verkhusha VV, Testa I

Nat Commun 14 (1) 8402 [2023-12-19; online 2023-12-19]

Integrated Microscopy Technologies Stockholm [Service]

PubMed DOI Crossref

Dissecting the genetic landscape of GPCR signaling through phenotypic profiling in C. elegans.

Pu L, Wang J, Lu Q, ..., Henriksson J, Chen C

Nat Commun 14 (1) 8410 [2023-12-18; online 2023-12-18]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

CENP-A and CENP-B collaborate to create an open centromeric chromatin state.

Nagpal H, Ali-Ahmad A, Hirano Y, ..., Sekulić N, Fierz B

Nat Commun 14 (1) 8227 [2023-12-12; online 2023-12-12]

Cryo-EM [Service]

PubMed DOI Crossref

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes

Rönn T, Ofori JK, Perfilyev A, ..., Bacos K, Ling C

Nat Commun 14 (1) 8040 [2023-12-12; online 2023-12-12]

Swedish Metabolomics Centre (SMC) [Collaborative]

PubMed DOI Crossref

Phyloecology of nitrate ammonifiers and their importance relative to denitrifiers in global terrestrial biomes.

Saghaï A, Pold G, Jones CM, Hallin S

Nat Commun 14 (1) 8249 [2023-12-12; online 2023-12-12]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

The formation of the Indo-Pacific montane avifauna.

Reeve AH, Kennedy JD, Pujolar JM, ..., Nylander JAA, Jønsson KA

Nat Commun 14 (1) 8215 [2023-12-11; online 2023-12-11]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation.

Mälarstig A, Grassmann F, Dahl L, ..., Czene K, Hedman ÅK

Nat Commun 14 (1) 7680 [2023-11-24; online 2023-11-24]

Affinity Proteomics Uppsala [Service] Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

The heat shock protein LarA activates the Lon protease in response to proteotoxic stress.

Omnus DJ, Fink MJ, Kallazhi A, ..., Landreh M, Jonas K

Nat Commun 14 (1) 7636 [2023-11-22; online 2023-11-22]

Global Proteomics and Proteogenomics [Service]

PubMed DOI Crossref

Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors.

Chiaro J, Antignani G, Feola S, ..., Lehtiö J, Cerullo V

Nat Commun 14 (1) 7056 [2023-11-03; online 2023-11-03]

Global Proteomics and Proteogenomics [Technology development]

PubMed DOI Crossref

Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis.

Åkesson J, Hojjati S, Hellberg S, ..., Ernerudh J, Gustafsson M

Nat Commun 14 (1) 6903 [2023-10-30; online 2023-10-30]

Affinity Proteomics Uppsala [Service] NGI Proteomics [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Low mutation rate in epaulette sharks is consistent with a slow rate of evolution in sharks.

Sendell-Price AT, Tulenko FJ, Pettersson M, ..., Andersson L, Schartl M

Nat Commun 14 (1) 6628 [2023-10-19; online 2023-10-19]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Design, structure and plasma binding of ancestral β-CoV scaffold antigens.

Hueting D, Schriever K, Sun R, ..., Andréll J, Syrén PO

Nat Commun 14 (1) 6527 [2023-10-16; online 2023-10-16]

Cryo-EM [Service] Drug Discovery and Development (DDD) [Service]

PubMed DOI Crossref

Miniature spatial transcriptomics for studying parasite-endosymbiont relationships at the micro scale.

Sounart H, Voronin D, Masarapu Y, ..., Ghedin E, Giacomello S

Nat Commun 14 (1) 6500 [2023-10-14; online 2023-10-14]

Bioinformatics Support for Computational Resources [Service]

PubMed DOI Crossref

Rewiring of the promoter-enhancer interactome and regulatory landscape in glioblastoma orchestrates gene expression underlying neurogliomal synaptic communication.

Chakraborty C, Nissen I, Vincent CA, ..., Hörnblad A, Remeseiro S

Nat Commun 14 (1) 6446 [2023-10-13; online 2023-10-13]

Bioinformatics Long-term Support WABI [Service] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Service]

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Targeting Toll-like receptor-driven systemic inflammation by engineering an innate structural fold into drugs.

Petruk G, Puthia M, Samsudin F, ..., Lindstedt S, Schmidtchen A

Nat Commun 14 (1) 6097 [2023-09-29; online 2023-09-29]

Clinical Genomics Lund [Service] Structural Proteomics [Collaborative]

PubMed DOI Crossref

A subset of type-II collagen-binding antibodies prevents experimental arthritis by inhibiting FCGR3 signaling in neutrophils.

Xu Z, Xu B, Lundström SL, ..., Zubarev RA, Holmdahl R

Nat Commun 14 (1) 5949 [2023-09-23; online 2023-09-23]

Drug Discovery and Development (DDD) [Collaborative]

PubMed DOI Crossref

Comprehensive proteomics and meta-analysis of COVID-19 host response.

Babačić H, Christ W, Araújo JE, ..., Klingström J, Pernemalm M

Nat Commun 14 (1) 5921 [2023-09-22; online 2023-09-22]

Global Proteomics and Proteogenomics [Collaborative]

PubMed DOI Crossref

Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.

He Y, Kaya I, Shariatgorji R, ..., Andren PE, Svenningsson P

Nat Commun 14 (1) 5804 [2023-09-19; online 2023-09-19]

Spatial Mass Spectrometry [Collaborative]

PubMed DOI Crossref

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

Mihalič F, Benz C, Kassa E, ..., Jemth P, Ivarsson Y

Nat Commun 14 (1) 5636 [2023-09-13; online 2023-09-13]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Placental growth factor exerts a dual function for cardiomyogenesis and vasculogenesis during heart development.

Witman N, Zhou C, Häneke T, ..., Chien KR, Sahara M

Nat Commun 14 (1) 5435 [2023-09-05; online 2023-09-05]

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The interplay between dietary fatty acids and gut microbiota influences host metabolism and hepatic steatosis.

Schoeler M, Ellero-Simatos S, Birkner T, ..., Burcelin R, Caesar R

Nat Commun 14 (1) 5329 [2023-09-01; online 2023-09-01]

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Long-read whole-genome analysis of human single cells.

Hård J, Mold JE, Eisfeldt J, ..., Michaëlsson J, Ameur A

Nat Commun 14 (1) 5164 [2023-08-24; online 2023-08-24]

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Atomic-level structure determination of amorphous molecular solids by NMR.

Cordova M, Moutzouri P, Nilsson Lill SO, ..., Schantz S, Emsley L

Nat Commun 14 (1) 5138 [2023-08-23; online 2023-08-23]

Swedish NMR Centre (SNC) [Collaborative]

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An idiosyncratic zonated stroma encapsulates desmoplastic liver metastases and originates from injured liver.

Fernández Moro C, Geyer N, Harrizi S, ..., Bozóky B, Gerling M

Nat Commun 14 (1) 5024 [2023-08-18; online 2023-08-18]

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GATA2 mitotic bookmarking is required for definitive haematopoiesis.

Silvério-Alves R, Kurochkin I, Rydström A, ..., Martin-Gonzalez J, Pereira CF

Nat Commun 14 (1) 4645 [2023-08-14; online 2023-08-14]

Clinical Genomics Lund [Service]

PubMed DOI Crossref

Complementarity-determining region clustering may cause CAR-T cell dysfunction.

Sarén T, Saronio G, Marti Torrell P, ..., Yu D, Essand M

Nat Commun 14 (1) 4732 [2023-08-10; online 2023-08-10]

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Genetic insights into resting heart rate and its role in cardiovascular disease.

van de Vegte YJ, Eppinga RN, van der Ende MY, ..., Verweij N, van der Harst P

Nat Commun 14 (1) 4646 [2023-08-02; online 2023-08-02]

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Patrilocality and hunter-gatherer-related ancestry of populations in East-Central Europe during the Middle Bronze Age.

Chyleński M, Makarowicz P, Juras A, ..., Jakobsson M, Malmström H

Nat Commun 14 (1) 4395 [2023-08-01; online 2023-08-01]

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Salicylic acid metabolism and signalling coordinate senescence initiation in aspen in nature.

Lihavainen J, Šimura J, Bag P, ..., Ljung K, Jansson S

Nat Commun 14 (1) 4288 [2023-07-18; online 2023-07-18]

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Next generation pan-cancer blood proteome profiling using proximity extension assay.

Álvez MB, Edfors F, von Feilitzen K, ..., Fagerberg L, Uhlén M

Nat Commun 14 (1) 4308 [2023-07-18; online 2023-07-18]

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Unmodified rabies mRNA vaccine elicits high cross-neutralizing antibody titers and diverse B cell memory responses.

Hellgren F, Cagigi A, Arcoverde Cerveira R, ..., Petsch B, Loré K

Nat Commun 14 (1) 3713 [2023-06-22; online 2023-06-22]

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Flavodiiron-mediated O2 photoreduction at photosystem I acceptor-side provides photoprotection to conifer thylakoids in early spring.

Bag P, Shutova T, Shevela D, ..., Messinger J, Jansson S

Nat Commun 14 (1) 3210 [2023-06-03; online 2023-06-03]

Swedish Metabolomics Centre (SMC) [Service]

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Directionality of developing skeletal muscles is set by mechanical forces.

Sunadome K, Erickson AG, Kah D, ..., Fried K, Adameyko I

Nat Commun 14 (1) 3060 [2023-05-27; online 2023-05-27]

Integrated Microscopy Technologies Stockholm [Service]

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Cisplatin toxicity is counteracted by the activation of the p38/ATF-7 signaling pathway in post-mitotic C. elegans.

Raj D, Kraish B, Martikainen J, ..., Kao G, Naredi P

Nat Commun 14 (1) 2886 [2023-05-20; online 2023-05-20]

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Base-resolution UV footprinting by sequencing reveals distinctive damage signatures for DNA-binding proteins.

Elliott K, Singh VK, Boström M, Larsson E

Nat Commun 14 (1) 2701 [2023-05-11; online 2023-05-11]

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Grahnemo L, Nethander M, Coward E, ..., Hveem K, Ohlsson C

Nat Commun 14 (1) 2250 [2023-04-20; online 2023-04-20]

Clinical Genomics Gothenburg [Collaborative]

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Delayed generation of functional virus-specific circulating T follicular helper cells correlates with severe COVID-19.

Yu M, Charles A, Cagigi A, ..., Loré K, Smed-Sörensen A

Nat Commun 14 (1) 2164 [2023-04-15; online 2023-04-15]

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Type I interferon shapes brain distribution and tropism of tick-borne flavivirus

Chotiwan N, Rosendal E, Willekens SMA, ..., Marcellino D, Överby AK

Nat Commun 14 (1) - [2023-04-10; online 2023-04-10]

Integrated Microscopy Technologies Umeå [Service]

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The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.

Gallego P, Garcia-Bonete MJ, Trillo-Muyo S, ..., Johansson MEV, Hansson GC

Nat Commun 14 (1) 1969 [2023-04-08; online 2023-04-08]

Cryo-EM [Service]

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Shuoker B, Pichler MJ, Jin C, ..., Karlsson NG, Abou Hachem M

Nat Commun 14 (1) 1833 [2023-04-01; online 2023-04-01]

Glycoproteomics and MS Proteomics [Collaborative]

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Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia.

Woodward EL, Yang M, Moura-Castro LH, ..., Foijer F, Paulsson K

Nat Commun 14 (1) 1658 [2023-03-25; online 2023-03-25]

Clinical Genomics Lund [Service]

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Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants.

Mäkelä AR, Uğurlu H, Hannula L, ..., Rissanen I, Saksela K

Nat Commun 14 (1) 1637 [2023-03-24; online 2023-03-24]

Cryo-EM [Service]

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Correlates of protection and viral load trajectories in omicron breakthrough infections in triple vaccinated healthcare workers.

Marking U, Havervall S, Norin NG, ..., Klingström J, Thålin C

Nat Commun 14 (1) 1577 [2023-03-22; online 2023-03-22]

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An integrated single cell and spatial transcriptomic map of human white adipose tissue.

Massier L, Jalkanen J, Elmastas M, ..., Rydén M, Mejhert N

Nat Commun 14 (1) 1438 [2023-03-15; online 2023-03-15]

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Real-time single-molecule 3D tracking in E. coli based on cross-entropy minimization.

Amselem E, Broadwater B, Hävermark T, Johansson M, Elf J

Nat Commun 14 (1) 1336 [2023-03-11; online 2023-03-11]

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ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors.

Mainwaring OJ, Weishaupt H, Zhao M, ..., Hutter S, Swartling FJ

Nat Commun 14 (1) 1221 [2023-03-03; online 2023-03-03]

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Structure and mechanism of a tripartite ATP-independent periplasmic TRAP transporter.

Davies JS, Currie MJ, North RA, ..., Mace PD, Dobson RCJ

Nat Commun 14 (1) 1120 [2023-02-27; online 2023-02-27]

Cryo-EM [Collaborative]

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Reconstructing clonal tree for phylo-phenotypic characterization of cancer using single-cell transcriptomics.

Jun S, Toosi H, Mold J, ..., Roth A, Lagergren J

Nat Commun 14 (1) 982 [2023-02-22; online 2023-02-22]

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Reproducing extracellular matrix adverse remodelling of non-ST myocardial infarction in a large animal model.

Contessotto P, Spelat R, Ferro F, ..., Pandit A, Da Costa M

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Glycoproteomics and MS Proteomics [Collaborative]

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Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.

Parajuli NP, Emmerich A, Mandava CS, Pavlov MY, Sanyal S

Nat Commun 14 (1) 918 [2023-02-17; online 2023-02-17]

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Li B, Zeis P, Zhang Y, ..., Steinmetz LM, Pelechano V

Nat Commun 14 (1) 910 [2023-02-17; online 2023-02-17]

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Huang P, Venskutonytė R, Prasad RB, ..., Artner I, Lindkvist-Petersson K

Nat Commun 14 (1) 600 [2023-02-03; online 2023-02-03]

Cryo-EM [Service]

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Inversions maintain differences between migratory phenotypes of a songbird.

Lundberg M, Mackintosh A, Petri A, Bensch S

Nat Commun 14 (1) 452 [2023-01-27; online 2023-01-27]

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Early response evaluation by single cell signaling profiling in acute myeloid leukemia.

Tislevoll BS, Hellesøy M, Fagerholt OHE, ..., Blaser N, Gjertsen BT

Nat Commun 14 (1) 115 [2023-01-07; online 2023-01-07]

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Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis.

Angelini G, Castagneto-Gissey L, Salinari S, ..., Tremaroli V, Mingrone G

Nat Commun 13 (1) 7715 [2022-12-13; online 2022-12-13]

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Structural mechanism of signal transduction in a phytochrome histidine kinase.

Wahlgren WY, Claesson E, Tuure I, ..., Takala H, Westenhoff S

Nat Commun 13 (1) 7673 [2022-12-12; online 2022-12-12]

Cryo-EM [Service]

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Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and embryogenesis.

Ruiz M, Devkota R, Panagaki D, ..., Borén J, Pilon M

Nat Commun 13 (1) 7162 [2022-11-22; online 2022-11-22]

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Structure of the reduced microsporidian proteasome bound by PI31-like peptides in dormant spores.

Jespersen N, Ehrenbolger K, Winiger RR, ..., Vossbrinck CR, Barandun J

Nat Commun 13 (1) 6962 [2022-11-15; online 2022-11-15]

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A multivesicular body-like organelle mediates stimulus-regulated trafficking of olfactory ciliary transduction proteins.

Maurya DK, Berghard A, Bohm S

Nat Commun 13 (1) 6889 [2022-11-12; online 2022-11-12]

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Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.

Liu L, Khan A, Sanchez-Rodriguez E, ..., Gharavi AG, Kiryluk K

Nat Commun 13 (1) 6859 [2022-11-11; online 2022-11-11]

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FRET-FISH probes chromatin compaction at individual genomic loci in single cells.

Mota A, Berezicki S, Wernersson E, ..., Crosetto N, Bienko M

Nat Commun 13 (1) 6680 [2022-11-05; online 2022-11-05]

Spatial Proteomics [Collaborative]

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Proteogenomics refines the molecular classification of chronic lymphocytic leukemia

Herbst SA, Vesterlund M, Helmboldt AJ, ..., Lehtiö J, Dietrich S

Nat Commun 13 (1) 6226 [2022-10-20; online 2022-10-20]

Global Proteomics and Proteogenomics [Technology development]

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Rapid antibiotic susceptibility testing and species identification for mixed samples.

Kandavalli V, Karempudi P, Larsson J, Elf J

Nat Commun 13 (1) 6215 [2022-10-20; online 2022-10-20]

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Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements.

Tobiasson V, Berzina I, Amunts A

Nat Commun 13 (1) 6132 [2022-10-17; online 2022-10-17]

Cryo-EM [Service]

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TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis

Petkevicius K, Palmgren H, Glover MS, ..., Maresca M, Peng XR

Nat Commun 13 (1) 6020 [2022-10-14; online 2022-10-14]

Swedish Metabolomics Centre (SMC) [Service]

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Manganese-driven CoQ deficiency.

Diessl J, Berndtsson J, Broeskamp F, ..., Ott M, Büttner S

Nat Commun 13 (1) 6061 [2022-10-13; online 2022-10-13]

Global Proteomics and Proteogenomics [Service]

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Spatiotemporal variations in retrovirus-host interactions among Darwin's finches.

Hill J, Lillie M, Pettersson ME, ..., Andersson L, Jern P

Nat Commun 13 (1) 6033 [2022-10-13; online 2022-10-13]

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Membrane-assisted assembly and selective secretory autophagy of enteroviruses.

Dahmane S, Kerviel A, Morado DR, ..., Altan-Bonnet N, Carlson LA

Nat Commun 13 (1) 5986 [2022-10-10; online 2022-10-10]

Cryo-EM [Service]

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Spatio-temporal analysis of prostate tumors in situ suggests pre-existence of treatment-resistant clones.

Marklund M, Schultz N, Friedrich S, ..., Sonnhammer E, Lundeberg J

Nat Commun 13 (1) 5475 [2022-09-17; online 2022-09-17]

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Terrigenous dissolved organic matter persists in the energy-limited deep groundwaters of the Fennoscandian Shield.

Osterholz H, Turner S, Alakangas LJ, ..., Kalinowski BE, Dopson M

Nat Commun 13 (1) 4837 [2022-08-17; online 2022-08-17]

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A method for Boolean analysis of protein interactions at a molecular level.

Raykova D, Kermpatsou D, Malmqvist T, ..., Kampf C, Söderberg O

Nat Commun 13 (1) 4755 [2022-08-13; online 2022-08-13]

BioImage Informatics [Collaborative]

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Scarf enables a highly memory-efficient analysis of large-scale single-cell genomics data.

Dhapola P, Rodhe J, Olofzon R, ..., Soneji S, Karlsson G

Nat Commun 13 (1) 4616 [2022-08-08; online 2022-08-08]

Clinical Genomics Lund [Service]

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Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria.

Li P, Hendricks AL, Wang Y, ..., Wang K, Gourdon P

Nat Commun 13 (1) 4339 [2022-07-27; online 2022-07-27]

Cryo-EM

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Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.

Khatri B, Tessneer KL, Rasmussen A, ..., Nordmark G, Lessard CJ

Nat Commun 13 (1) 4287 [2022-07-27; online 2022-07-27]

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Equilibrated evolution of the mixed auto-/allopolyploid haplotype-resolved genome of the invasive hexaploid Prussian carp.

Kuhl H, Du K, Schartl M, ..., Stöck M, Lamatsch DK

Nat Commun 13 (1) 4092 [2022-07-14; online 2022-07-14]

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Ultra-sensitive monitoring of leukemia patients using superRCA mutation detection assays.

Chen L, Eriksson A, Weström S, ..., Cavelier L, Landegren U

Nat Commun 13 (1) 4033 [2022-07-12; online 2022-07-12]

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Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification.

Petitpré C, Faure L, Uhl P, ..., Hadjab S, Lallemend F

Nat Commun 13 (1) 3878 [2022-07-05; online 2022-07-05]

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Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0.

Domenzain I, Sánchez B, Anton M, ..., Sonnenschein N, Nielsen J

Nat Commun 13 (1) 3766 [2022-06-30; online 2022-06-30]

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Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite.

Kotila T, Wioland H, Selvaraj M, ..., Romet-Lemonne G, Lappalainen P

Nat Commun 13 (1) 3442 [2022-06-15; online 2022-06-15]

Cryo-EM [Service]

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Asgard archaea shed light on the evolutionary origins of the eukaryotic ubiquitin-ESCRT machinery.

Hatano T, Palani S, Papatziamou D, ..., Robinson NP, Balasubramanian M

Nat Commun 13 (1) 3398 [2022-06-13; online 2022-06-13]

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Robust derivation of transplantable dopamine neurons from human pluripotent stem cells by timed retinoic acid delivery.

Alekseenko Z, Dias JM, Adler AF, ..., Parmar M, Ericson J

Nat Commun 13 (1) 3046 [2022-06-01; online 2022-06-01]

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Nitrogen represses haustoria formation through abscisic acid in the parasitic plant Phtheirospermum japonicum.

Kokla A, Leso M, Zhang X, ..., Yoshida S, Melnyk CW

Nat Commun 13 (1) 2976 [2022-05-27; online 2022-05-27]

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The long noncoding RNA ADIPINT regulates human adipocyte metabolism via pyruvate carboxylase.

Kerr AG, Wang Z, Wang N, ..., Arner P, Gao H

Nat Commun 13 (1) 2958 [2022-05-26; online 2022-05-26]

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A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.

Rozman Grinberg I, Martínez-Carranza M, Bimai O, ..., Sjöberg BM, Stenmark P

Nat Commun 13 (1) 2700 [2022-05-16; online 2022-05-16]

Cryo-EM [Service]

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Large differences in carbohydrate degradation and transport potential among lichen fungal symbionts.

Resl P, Bujold AR, Tagirdzhanova G, ..., Willis LM, Spribille T

Nat Commun 13 (1) 2634 [2022-05-12; online 2022-05-12]

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Contribution of rare whole-genome sequencing variants to plasma protein levels and the missing heritability.

Kierczak M, Rafati N, Höglund J, ..., Karlsson T, Johansson Å

Nat Commun 13 (1) 2532 [2022-05-09; online 2022-05-09]

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Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival.

Lu X, Maturi NP, Jarvius M, ..., Uhrbom L, Chen X

Nat Commun 13 (1) 2236 [2022-04-25; online 2022-04-25]

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App-based COVID-19 syndromic surveillance and prediction of hospital admissions in COVID Symptom Study Sweden.

Kennedy B, Fitipaldi H, Hammar U, ..., Franks PW, Fall T

Nat Commun 13 (1) 2110 [2022-04-21; online 2022-04-21]

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Structural basis for PoxtA-mediated resistance to phenicol and oxazolidinone antibiotics.

Crowe-McAuliffe C, Murina V, Turnbull KJ, ..., Wilson DN, Hauryliuk V

Nat Commun 13 (1) 1860 [2022-04-06; online 2022-04-06]

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Direct measurements of mRNA translation kinetics in living cells.

Metelev M, Lundin E, Volkov IL, ..., Elf J, Johansson M

Nat Commun 13 (1) 1852 [2022-04-06; online 2022-04-06]

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Integrative multi-omics and drug response profiling of childhood acute lymphoblastic leukemia cell lines.

Leo IR, Aswad L, Stahl M, ..., Vesterlund M, Jafari R

Nat Commun 13 (1) 1691 [2022-03-30; online 2022-03-30]

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Norway spruce postglacial recolonization of Fennoscandia.

Nota K, Klaminder J, Milesi P, ..., Suyama Y, Parducci L

Nat Commun 13 (1) 1333 [2022-03-14; online 2022-03-14]

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The spatial transcriptomic landscape of the healing mouse intestine following damage.

Parigi SM, Larsson L, Das S, ..., Lundeberg J, Villablanca EJ

Nat Commun 13 (1) 828 [2022-02-11; online 2022-02-11]

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CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations.

Höijer I, Emmanouilidou A, Östlund R, ..., den Hoed M, Ameur A

Nat Commun 13 (1) 627 [2022-02-02; online 2022-02-02]

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PplD is a de-N-acetylase of the cell wall linkage unit of streptococcal rhamnopolysaccharides.

Rush JS, Parajuli P, Ruda A, ..., Widmalm G, Korotkova N

Nat Commun 13 (1) 590 [2022-02-01; online 2022-02-01]

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The formation of avian montane diversity across barriers and along elevational gradients.

Pujolar JM, Blom MPK, Reeve AH, ..., Irestedt M, Jønsson KA

Nat Commun 13 (1) 268 [2022-01-12; online 2022-01-12]

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Canonical WNT signaling-dependent gating of MYC requires a noncanonical CTCF function at a distal binding site.

Chachoua I, Tzelepis I, Dai H, ..., Mehmood R, Göndör A

Nat Commun 13 (1) 204 [2022-01-11; online 2022-01-11]

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Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus.

Tin A, Schlosser P, Matias-Garcia PR, ..., Teumer A, Köttgen A

Nat Commun 12 (1) 7173 [2021-12-09; online 2021-12-09]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Meta-analyses identify DNA methylation associated with kidney function and damage.

Schlosser P, Tin A, Matias-Garcia PR, ..., Köttgen A, Teumer A

Nat Commun 12 (1) 7174 [2021-12-09; online 2021-12-09]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Structural basis for transthyretin amyloid formation in vitreous body of the eye.

Iakovleva I, Hall M, Oelker M, ..., Anan I, Sauer-Eriksson AE

Nat Commun 12 (1) 7141 [2021-12-08; online 2021-12-08]

Cryo-EM [Collaborative] Structural Proteomics [Service]

PubMed DOI Crossref

Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver.

Hildebrandt F, Andersson A, Saarenpää S, ..., Lundeberg J, Ankarklev J

Nat Commun 12 (1) 7046 [2021-12-02; online 2021-12-02]

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ATR inhibition enables complete tumour regression in ALK-driven NB mouse models.

Szydzik J, Lind DE, Arefin B, ..., Hallberg B, Palmer RH

Nat Commun 12 (1) 6813 [2021-11-24; online 2021-11-24]

Glycoproteomics and MS Proteomics [Service]

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Single cell genomics reveals plastid-lacking Picozoa are close relatives of red algae.

Schön ME, Zlatogursky VV, Singh RP, ..., Wideman JG, Burki F

Nat Commun 12 (1) 6651 [2021-11-17; online 2021-11-17]

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Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4.

Grosche S, Marenholz I, Esparza-Gordillo J, ..., Xu C, Lee Y

Nat Commun 12 (1) 6618 [2021-11-16; online 2021-11-16]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation.

Sabatier P, Beusch CM, Saei AA, ..., Rodin S, Zubarev RA

Nat Commun 12 (1) 6558 [2021-11-12; online 2021-11-12] Open Access

Chemical Proteomics [Technology development]

PubMed DOI Crossref

Elevated circulating follistatin associates with an increased risk of type 2 diabetes.

Wu C, Borné Y, Gao R, ..., Groop L, De Marinis Y

Nat Commun 12 (1) 6486 [2021-11-10; online 2021-11-10]

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De novo biosynthesis of bioactive isoflavonoids by engineered yeast cell factories.

Liu Q, Liu Y, Li G, ..., Chen Y, Nielsen J

Nat Commun 12 (1) 6085 [2021-10-19; online 2021-10-19]

Chalmers Mass Spectrometry Infrastructure [Service]

PubMed DOI Crossref

Spatial deconvolution of HER2-positive breast cancer delineates tumor-associated cell type interactions.

Andersson A, Larsson L, Stenbeck L, ..., Engblom C, Lundeberg J

Nat Commun 12 (1) 6012 [2021-10-14; online 2021-10-14]

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Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors.

Bedoya-Reina OC, Li W, Arceo M, ..., Kogner P, Schlisio S

Nat Commun 12 (1) 5309 [2021-09-07; online 2021-09-07]

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Structure of the native pyruvate dehydrogenase complex reveals the mechanism of substrate insertion.

Škerlová J, Berndtsson J, Nolte H, Ott M, Stenmark P

Nat Commun 12 (1) 5277 [2021-09-06; online 2021-09-06]

Cryo-EM [Service]

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Amnion signals are essential for mesoderm formation in primates.

Yang R, Goedel A, Kang Y, ..., Niu Y, Chien KR

Nat Commun 12 (1) 5126 [2021-08-26; online 2021-08-26]

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A simple pressure-assisted method for MicroED specimen preparation.

Zhao J, Xu H, Lebrette H, ..., Högbom M, Zou X

Nat Commun 12 (1) 5036 [2021-08-19; online 2021-08-19]

Cryo-EM [Collaborative]

PubMed DOI Crossref

Energy efficiency and biological interactions define the core microbiome of deep oligotrophic groundwater.

Mehrshad M, Lopez-Fernandez M, Sundh J, ..., Bertilsson S, Dopson M

Nat Commun 12 (1) 4253 [2021-07-12; online 2021-07-12]

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A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.

Jhun M, Mendelson M, Wilson R, ..., Irvin MR, Assimes TL

Nat Commun 12 (1) 3987 [2021-06-28; online 2021-06-28]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Structure and transport mechanism of P5B-ATPases.

Li P, Wang K, Salustros N, Grønberg C, Gourdon P

Nat Commun 12 (1) 3973 [2021-06-25; online 2021-06-25]

Cryo-EM [Service]

PubMed DOI Crossref

COVseq is a cost-effective workflow for mass-scale SARS-CoV-2 genomic surveillance.

Simonetti M, Zhang N, Harbers L, ..., Ghisetti V, Crosetto N

Nat Commun 12 (1) 3903 [2021-06-23; online 2021-06-23]

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Multianalyte serology in home-sampled blood enables an unbiased assessment of the immune response against SARS-CoV-2.

Roxhed N, Bendes A, Dale M, ..., Fredolini C, Schwenk JM

Nat Commun 12 (1) 3695 [2021-06-17; online 2021-06-17]

Affinity Proteomics Stockholm [Technology development]

PubMed DOI Crossref

Structural basis of ABCF-mediated resistance to pleuromutilin, lincosamide, and streptogramin A antibiotics in Gram-positive pathogens.

Crowe-McAuliffe C, Murina V, Turnbull KJ, ..., Hauryliuk V, Wilson DN

Nat Commun 12 (1) 3577 [2021-06-11; online 2021-06-11]

Cryo-EM [Service]

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Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation.

Karampelias C, Rezanejad H, Rosko M, ..., Korbutt GS, Andersson O

Nat Commun 12 (1) 3362 [2021-06-07; online 2021-06-07]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.

de Rojas I, Moreno-Grau S, Tesi N, ..., van der Lee SJ, Ruiz A

Nat Commun 12 (1) 3417 [2021-06-07; online 2021-06-07]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

RNA atlas of human bacterial pathogens uncovers stress dynamics linked to infection.

Avican K, Aldahdooh J, Togninalli M, ..., Rhen M, Fällman M

Nat Commun 12 (1) 3282 [2021-06-02; online 2021-06-02]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Continent-wide genomic signatures of adaptation to urbanisation in a songbird across Europe.

Salmón P, Jacobs A, Ahrén D, ..., Visser ME, Isaksson C

Nat Commun 12 (1) 2983 [2021-05-20; online 2021-05-20]

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Genomic insights into the conservation status of the world's last remaining Sumatran rhinoceros populations.

von Seth J, Dussex N, Díez-Del-Molino D, ..., Götherström A, Dalén L

Nat Commun 12 (1) 2393 [2021-04-26; online 2021-04-26]

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Phenological shifts in lake stratification under climate change.

Woolway RI, Sharma S, Weyhenmeyer GA, ..., Thiery W, Jennings E

Nat Commun 12 (1) 2318 [2021-04-19; online 2021-04-19]

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A molecular timescale for eukaryote evolution with implications for the origin of red algal-derived plastids.

Strassert JFH, Irisarri I, Williams TA, Burki F

Nat Commun 12 (1) 1879 [2021-03-25; online 2021-03-25]

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Single cell transcriptomics of primate sensory neurons identifies cell types associated with chronic pain.

Kupari J, Usoskin D, Parisien M, ..., Diatchenko L, Ernfors P

Nat Commun 12 (1) 1510 [2021-03-08; online 2021-03-08]

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System-wide identification and prioritization of enzyme substrates by thermal analysis.

Saei AA, Beusch CM, Sabatier P, ..., Schüler H, Zubarev RA

Nat Commun 12 (1) 1296 [2021-02-26; online 2021-02-26] Open Access

Chemical Proteomics [Technology development]

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Biological and therapeutic implications of a unique subtype of NPM1 mutated AML.

Mer AS, Heath EM, Madani Tonekaboni SA, ..., Schimmer AD, Haibe-Kains B

Nat Commun 12 (1) 1054 [2021-02-16; online 2021-02-16]

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Asymmetric introgression reveals the genetic architecture of a plumage trait.

Semenov GA, Linck E, Enbody ED, ..., Andersson L, Taylor SA

Nat Commun 12 (1) 1019 [2021-02-15; online 2021-02-15]

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Distinct subtypes of proprioceptive dorsal root ganglion neurons regulate adaptive proprioception in mice.

Wu H, Petitpré C, Fontanet P, ..., Hadjab S, Lallemend F

Nat Commun 12 (1) 1026 [2021-02-15; online 2021-02-15]

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GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility.

Eriksson D, Røyrvik EC, Aranda-Guillén M, ..., Kämpe O, Husebye ES

Nat Commun 12 (1) 959 [2021-02-11; online 2021-02-11]

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Endophilin A2 deficiency protects rodents from autoimmune arthritis by modulating T cell activation.

Norin U, Rintisch C, Meng L, ..., Bäckdahl L, Holmdahl R

Nat Commun 12 (1) 610 [2021-01-27; online 2021-01-27]

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Structure of a full-length bacterial polysaccharide co-polymerase.

Wiseman B, Nitharwal RG, Widmalm G, Högbom M

Nat Commun 12 (1) 369 [2021-01-14; online 2021-01-14]

Cryo-EM [Service]

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Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution.

Cunha ES, Chen X, Sanz-Gaitero M, Mills DJ, Luecke H

Nat Commun 12 (1) 230 [2021-01-11; online 2021-01-11]

Cryo-EM [Service]

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Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 24 [2021-01-05; online 2021-01-05]

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PubMed DOI Crossref

Direct energy transfer from photosystem II to photosystem I confers winter sustainability in Scots Pine.

Bag P, Chukhutsina V, Zhang Z, ..., Holzwarth AR, Jansson S

Nat Commun 11 (1) 6388 [2020-12-15; online 2020-12-15]

Integrated Microscopy Technologies Umeå [Service]

PubMed DOI Crossref

Distinct oligodendrocyte populations have spatial preference and different responses to spinal cord injury

Floriddia EM, Lourenço T, Zhang S, ..., Nilsson M, Castelo-Branco G

Nat Commun 11 (1) 5860 [2020-11-17; online 2020-11-17]

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Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.

Tarbier M, Mackowiak SD, Frade J, ..., Gallant CJ, Friedländer MR

Nat Commun 11 (1) 5445 [2020-10-28; online 2020-10-28]

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Type III ATP synthase is a symmetry-deviated dimer that induces membrane curvature through tetramerization.

Flygaard RK, Mühleip A, Tobiasson V, Amunts A

Nat Commun 11 (1) 5342 [2020-10-22; online 2020-10-22]

Cryo-EM [Service] Global Proteomics and Proteogenomics [Service]

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A high-stringency blueprint of the human proteome.

Adhikari S, Nice EC, Deutsch EW, ..., Aebersold R, Baker MS

Nat Commun 11 (1) 5301 [2020-10-16; online 2020-10-16]

Affinity Proteomics Stockholm [Collaborative]

PubMed DOI Crossref

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.

Nowak K, Rosenthal F, Karlberg T, ..., Leslie Pedrioli DM, Hottiger MO

Nat Commun 11 (1) 5199 [2020-10-15; online 2020-10-15]

Protein Science Facility (PSF) [Service]

PubMed DOI Crossref

Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi.

Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A

Nat Commun 11 (1) 5187 [2020-10-14; online 2020-10-14]

Cryo-EM [Service] Global Proteomics and Proteogenomics [Service]

PubMed DOI Crossref

An embryonic stem cell-specific heterochromatin state promotes core histone exchange in the absence of DNA accessibility.

Navarro C, Lyu J, Katsori AM, Caridha R, Elsässer SJ

Nat Commun 11 (1) 5095 [2020-10-09; online 2020-10-09]

Protein Science Facility (PSF) [Service]

PubMed DOI Crossref

SARS-CoV-2 exposure, symptoms and seroprevalence in healthcare workers in Sweden.

Rudberg AS, Havervall S, Månberg A, ..., Hober S, Thålin C

Nat Commun 11 (1) 5064 [2020-10-08; online 2020-10-08]

Autoimmunity and Serology Profiling [Collaborative]

PubMed DOI Crossref

Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders.

Wang T, Hoekzema K, Vecchio D, ..., Xia K, Eichler EE

Nat Commun 11 (1) 4932 [2020-10-01; online 2020-10-01]

Clinical Genomics Stockholm [Service]

PubMed DOI Crossref

Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth.

Krivanek J, Soldatov RA, Kastriti ME, ..., Kharchenko PV, Adameyko I

Nat Commun 11 (1) 4816 [2020-09-23; online 2020-09-23]

Eukaryotic Single Cell Genomics (ESCG) [Service]

PubMed DOI Crossref

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

Bailey MH, Meyerson WU, Dursi LJ, ..., Ding L, PCAWG Consortium

Nat Commun 11 (1) 4748 [2020-09-21; online 2020-09-21]

Clinical Genomics Uppsala [Service]

PubMed DOI Crossref

Integration of molecular profiles in a longitudinal wellness profiling cohort.

Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L

Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]

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An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.

Hanke L, Vidakovics Perez L, Sheward DJ, ..., Murrell B, McInerney GM

Nat Commun 11 (1) 4420 [2020-09-04; online 2020-09-04]

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Sex differences in oncogenic mutational processes.

Li CH, Prokopec SD, Sun RX, ..., Boutros PC, PCAWG Consortium

Nat Commun 11 (1) 4330 [2020-08-28; online 2020-08-28]

Clinical Genomics Uppsala [Service]

PubMed DOI Crossref

Cell-surface receptors enable perception of extracellular cytokinins.

Antoniadi I, Novák O, Gelová Z, ..., Ljung K, Turnbull C

Nat Commun 11 (1) 4284 [2020-08-27; online 2020-08-27]

Swedish Metabolomics Centre (SMC) [Service]

PubMed DOI Crossref

Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates.

Faure L, Wang Y, Kastriti ME, ..., Adameyko I, Hadjab S

Nat Commun 11 (1) 4175 [2020-08-21; online 2020-08-21]

Bioinformatics Support for Computational Resources [Service] Eukaryotic Single Cell Genomics (ESCG) [Service]

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Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis.

Carlström KE, Zhu K, Ewing E, ..., Castelo-Branco G, Piehl F

Nat Commun 11 (1) 4071 [2020-08-13; online 2020-08-13]

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Discovery and population genomics of structural variation in a songbird genus.

Weissensteiner MH, Bunikis I, Catalán A, ..., Warmuth VM, Wolf JBW

Nat Commun 11 (1) 3403 [2020-07-07; online 2020-07-07]

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Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.

Wilkes MC, Siva K, Chen J, ..., Flygare J, Sakamoto KM

Nat Commun 11 (1) 3344 [2020-07-03; online 2020-07-03]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

PubMed DOI Crossref

Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage.

Ciudad S, Puig E, Botzanowski T, ..., Bardiaux B, Carulla N

Nat Commun 11 (1) 3014 [2020-06-15; online 2020-06-15]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Distinct pre-initiation steps in human mitochondrial translation.

Khawaja A, Itoh Y, Remes C, ..., Amunts A, Rorbach J

Nat Commun 11 (1) 2932 [2020-06-10; online 2020-06-10]

Cryo-EM [Service]

PubMed DOI Crossref

CYCLIN-B1/2 and -D1 act in opposition to coordinate cortical progenitor self-renewal and lineage commitment.

Hagey DW, Topcic D, Kee N, ..., Perlmann T, Muhr J

Nat Commun 11 (1) 2898 [2020-06-09; online 2020-06-09]

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PubMed DOI Crossref

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB

Nat Commun 11 (1) 2542 [2020-05-21; online 2020-05-21]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson's disease.

Tiklová K, Nolbrant S, Fiorenzano A, ..., Perlmann T, Parmar M

Nat Commun 11 (1) 2434 [2020-05-15; online 2020-05-15]

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Molecular profiling of driver events in metastatic uveal melanoma.

Karlsson J, Nilsson LM, Mitra S, ..., Olofsson Bagge R, Nilsson JA

Nat Commun 11 (1) 1894 [2020-04-20; online 2020-04-20]

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PubMed DOI Crossref

Increased burden of ultra-rare structural variants localizing to boundaries of topologically associated domains in schizophrenia.

Halvorsen M, Huh R, Oskolkov N, ..., Sullivan PF, Szatkiewicz JP

Nat Commun 11 (1) 1842 [2020-04-15; online 2020-04-15]

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PubMed DOI Crossref

Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells.

Plaza Reyes A, Petrus-Reurer S, Padrell Sánchez S, ..., Kvanta A, Lanner F

Nat Commun 11 (1) 1609 [2020-03-30; online 2020-03-30]

Bioinformatics Support for Computational Resources [Service] Eukaryotic Single Cell Genomics (ESCG) [Service]

PubMed DOI Crossref

Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA.

Madru C, Henneke G, Raia P, ..., Carroni M, Sauguet L

Nat Commun 11 (1) 1591 [2020-03-27; online 2020-03-27]

Cryo-EM [Collaborative]

PubMed DOI Crossref

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy.

Rendo V, Stoimenov I, Mateus A, ..., Cheong I, Sjöblom T

Nat Commun 11 (1) 1308 [2020-03-11; online 2020-03-11]

Bioinformatics Support for Computational Resources [Service] Chemical Biology Consortium Sweden (CBCS) [Collaborative] Drug Discovery and Development (DDD) [Service]

PubMed DOI Crossref

Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells.

Wagner M, Yoshihara M, Douagi I, ..., Lanner F, Damdimopoulou P

Nat Commun 11 (1) 1147 [2020-03-02; online 2020-03-02]

Bioinformatics Support for Computational Resources [Service] Eukaryotic Single Cell Genomics (ESCG) [Service]

PubMed DOI Crossref

Primary cell wall inspired micro containers as a step towards a synthetic plant cell.

Paulraj T, Wennmalm S, Wieland DCF, ..., Cárdenas M, Svagan AJ

Nat Commun 11 (1) 958 [2020-02-19; online 2020-02-19]

Integrated Microscopy Technologies Stockholm [Collaborative]

PubMed DOI Crossref

Clonal competition within complex evolutionary hierarchies shapes AML over time.

Sandén C, Lilljebjörn H, Orsmark Pietras C, ..., Ågerstam H, Fioretos T

Nat Commun 11 (1) 579 [2020-02-05; online 2020-02-05]

Clinical Genomics Lund

PubMed DOI Crossref

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity.

Pillon NJ, Gabriel BM, Dollet L, ..., Krook A, Zierath JR

Nat Commun 11 (1) 470 [2020-01-24; online 2020-01-24]

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PubMed DOI Crossref

The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.

Pinese M, Lacaze P, Rath EM, ..., Dinger ME, Thomas DM

Nat Commun 11 (1) 435 [2020-01-23; online 2020-01-23]

NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

PubMed DOI Crossref

A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice.

Purhonen J, Grigorjev V, Ekiert R, ..., Fellman V, Kallijärvi J

Nat Commun 11 (1) 322 [2020-01-16; online 2020-01-16]

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PubMed DOI Crossref

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.

Shah S, Henry A, Roselli C, ..., Swerdlow DI, Lumbers RT

Nat Commun 11 (1) 163 [2020-01-09; online 2020-01-09]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Integrative discovery of treatments for high-risk neuroblastoma.

Almstedt E, Elgendy R, Hekmati N, ..., Krona C, Nelander S

Nat Commun 11 (1) 71 [2020-01-03; online 2020-01-03]

Genome Engineering Zebrafish [Service]

PubMed DOI Crossref

A transposable element insertion is associated with an alternative life history strategy.

Woronik A, Tunström K, Perry MW, ..., Käkelä R, Wheat CW

Nat Commun 10 (1) 5757 [2019-12-17; online 2019-12-17]

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BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila.

Ueberschär M, Wang H, Zhang C, ..., Wen J, Dai Q

Nat Commun 10 (1) 5700 [2019-12-13; online 2019-12-13]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Saei AA, Beusch CM, Chernobrovkin A, ..., Végvári Á, Zubarev RA

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Chemical Proteomics [Technology development]

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Wang Y, Wu H, Fontanet P, ..., Hadjab S, Lallemend F

Nat Commun 10 (1) - [2019-12-00; online 2019-09-12]

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Gelali E, Girelli G, Matsumoto M, ..., Crosetto N, Bienko M

Nat Commun 10 (1) - [2019-12-00; online 2019-04-09]

Advanced FISH Technologies [Technology development] Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service]

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Towards a standardized bioinformatics infrastructure for N- and O-glycomics

Rojas-Macias MA, Mariethoz J, Andersson P, ..., Lisacek F, Karlsson NG

Nat Commun 10 (1) - [2019-12-00; online 2019-07-22]

Bioinformatics Support and Infrastructure [Technology development] Bioinformatics Support, Infrastructure and Training [Technology development] Glycoproteomics and MS Proteomics [Technology development]

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Programmed DNA elimination of germline development genes in songbirds.

Kinsella CM, Ruiz-Ruano FJ, Dion-Côté AM, ..., Forstmeier W, Suh A

Nat Commun 10 (1) 5468 [2019-11-29; online 2019-11-29]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Associations of autozygosity with a broad range of human phenotypes.

Clark DW, Okada Y, Moore KHS, ..., Kubo M, Wilson JF

Nat Commun 10 (1) 4957 [2019-10-31; online 2019-10-31]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Puma genomes from North and South America provide insights into the genomic consequences of inbreeding.

Saremi NF, Supple MA, Byrne A, ..., Wilmers CC, Shapiro B

Nat Commun 10 (1) 4769 [2019-10-18; online 2019-10-18]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Microbe-host interplay in atopic dermatitis and psoriasis.

Fyhrquist N, Muirhead G, Prast-Nielsen S, ..., Andersson B, Alenius H

Nat Commun 10 (1) 4703 [2019-10-16; online 2019-10-16]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

Teumer A, Li Y, Ghasemi S, ..., Pattaro C, Köttgen A

Nat Commun 10 (1) 4130 [2019-09-11; online 2019-09-11]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.

Akula MK, Ibrahim MX, Ivarsson EG, ..., Sayin VI, Bergo MO

Nat Commun 10 (1) 3975 [2019-09-04; online 2019-09-04]

Glycoproteomics and MS Proteomics [Service]

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Unique transcriptional and protein-expression signature in human lung tissue-resident NK cells.

Marquardt N, Kekäläinen E, Chen P, ..., Ljunggren HG, Michaëlsson J

Nat Commun 10 (1) 3841 [2019-08-26; online 2019-08-26]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Profiling surface proteins on individual exosomes using a proximity barcoding assay.

Wu D, Yan J, Shen X, ..., Landegren U, Kamali-Moghaddam M

Nat Commun 10 (1) 3854 [2019-08-26; online 2019-08-26]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Support for Computational Resources [Service] PLA and Single Cell Proteomics [Technology development]

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Genome-wide systematic identification of methyltransferase recognition and modification patterns.

Jensen TØ, Tellgren-Roth C, Redl S, ..., Pedersen LE, Nielsen AT

Nat Commun 10 (1) 3311 [2019-08-19; online 2019-08-19]

NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

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PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.

Costa TDF, Zhuang T, Lorent J, ..., Defilippi P, Strömblad S

Nat Commun 10 (1) 3589 [2019-08-09; online 2019-08-09]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.

Nirwan N, Itoh Y, Singh P, ..., Amunts A, Saikrishnan K

Nat Commun 10 (1) 3058 [2019-07-11; online 2019-07-11]

Cryo-EM [Service]

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Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data.

Shungin D, Haworth S, Divaris K, ..., Timpson NJ, Johansson I

Nat Commun 10 (1) 2773 [2019-06-24; online 2019-06-24]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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A quantitative Streptococcus pyogenes-human protein-protein interaction map reveals localization of opsonizing antibodies.

Happonen L, Hauri S, Svensson Birkedal G, ..., Malmström L, Malmström J

Nat Commun 10 (1) 2727 [2019-06-21; online 2019-06-21]

Structural Proteomics [Technology development]

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The viral protein corona directs viral pathogenesis and amyloid aggregation.

Ezzat K, Pernemalm M, Pålsson S, ..., Spetz AL, El Andaloussi S

Nat Commun 10 (1) 2331 [2019-05-27; online 2019-05-27]

Bioinformatics Support for Computational Resources [Service] Global Proteomics and Proteogenomics [Technology development]

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Spatial and temporal localization of immune transcripts defines hallmarks and diversity in the tuberculosis granuloma.

Carow B, Hauling T, Qian X, ..., Nilsson M, Rottenberg ME

Nat Commun 10 (1) 1823 [2019-04-23; online 2019-04-23]

In Situ Sequencing (ISS) [Collaborative]

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Neutrophil extracellular traps in the central nervous system hinder bacterial clearance during pneumococcal meningitis.

Mohanty T, Fisher J, Bakochi A, ..., Bentzer P, Linder A

Nat Commun 10 (1) 1667 [2019-04-10; online 2019-04-10]

Structural Proteomics [Collaborative]

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Breast cancer quantitative proteome and proteogenomic landscape.

Johansson HJ, Socciarelli F, Vacanti NM, ..., Børresen-Dale AL, Lehtiö J

Nat Commun 10 (1) 1600 [2019-04-08; online 2019-04-08]

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A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius.

Wang K, Sybers D, Maklad HR, ..., Lindås AC, Peeters E

Nat Commun 10 (1) 1542 [2019-04-04; online 2019-04-04]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia.

Yang M, Vesterlund M, Siavelis I, ..., Lehtiö J, Paulsson K

Nat Commun 10 (1) 1519 [2019-04-03; online 2019-04-03]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Lund [Service] Global Proteomics and Proteogenomics [Technology development]

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Polymer gels with tunable ionic Seebeck coefficient for ultra-sensitive printed thermopiles.

Zhao D, Martinelli A, Willfahrt A, ..., Fabiano S, Crispin X

Nat Commun 10 (1) 1093 [2019-03-06; online 2019-03-06]

Swedish NMR Centre (SNC) [Collaborative]

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Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development

Tiklová K, Björklund ÅK, Lahti L, ..., Parmar M, Perlmann T

Nat Commun 10 (1) 581 [2019-02-04; online 2019-02-04]

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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

Kilpeläinen TO, Bentley AR, Noordam R, ..., Rao DC, Loos RJF

Nat Commun 10 (1) 376 [2019-01-22; online 2019-01-22]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Rapid determination of quaternary protein structures in complex biological samples.

Hauri S, Khakzad H, Happonen L, ..., Malmström J, Malmström L

Nat Commun 10 (1) 192 [2019-01-14; online 2019-01-14]

Structural Proteomics [Technology development]

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Fecal pollution can explain antibiotic resistance gene abundances in anthropogenically impacted environments.

Karkman A, Pärnänen K, Larsson DGJ

Nat Commun 10 (1) 80 [2019-01-08; online 2019-01-08]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies.

Morris AP, Le TH, Wu H, ..., Humphreys BD, Franceschini N

Nat Commun 10 (1) 29 [2019-01-03; online 2019-01-03]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing.

Bartoschek M, Oskolkov N, Bocci M, ..., Björklund Å, Pietras K

Nat Commun 9 (1) 5150 [2018-12-04; online 2018-12-04]

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Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination

Gustafsson NMS, Färnegårdh K, Bonagas N, ..., Olin T, Helleday T

Nat Commun 9 (1) - [2018-12-00; online 2018-09-24]

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Convergent evolution of complex genomic rearrangements in two fungal meiotic drive elements

Svedberg J, Hosseini S, Chen J, ..., Lascoux M, Johannesson H

Nat Commun 9 (1) - [2018-12-00; online 2018-10-12]

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Somatic mutagenesis in satellite cells associates with human skeletal muscle aging

Franco I, Johansson A, Olsson K, ..., Fischer H, Eriksson M

Nat Commun 9 (1) - [2018-12-00; online 2018-02-23]

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GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes

Franceschini N, None , Giambartolomei C, ..., Casas JP, O’Donnell CJ

Nat Commun 9 (1) - [2018-12-00; online 2018-12-03]

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Aberrant splicing and defective mRNA production induced by somatic spliceosome mutations in myelodysplasia

Shiozawa Y, Malcovati L, Gallì A, ..., Ogawa S, Cazzola M

Nat Commun 9 (1) - [2018-12-00; online 2018-09-07]

Clinical Genomics Uppsala [Service]

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Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S

Nat Commun 9 (1) - [2018-12-00; online 2018-05-22]

Bioinformatics Support for Computational Resources [Service] Drug Discovery and Development (DDD) [Service]

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A comprehensive map coupling histone modifications with gene regulation in adult dopaminergic and serotonergic neurons

Södersten E, Toskas K, Rraklli V, ..., Perlmann T, Holmberg J

Nat Commun 9 (1) - [2018-12-00; online 2018-03-26]

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Enhanced validation of antibodies for research applications.

Edfors F, Hober A, Linderbäck K, ..., Forsström B, Uhlen M

Nat Commun 9 (1) 4130 [2018-10-08; online 2018-10-08]

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14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface.

Karlberg T, Hornyak P, Pinto AF, ..., Björkegren C, Schüler H

Nat Commun 9 (1) 3785 [2018-09-17; online 2018-09-17]

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Neuronal heterogeneity and stereotyped connectivity in the auditory afferent system.

Petitpré C, Wu H, Sharma A, ..., Hadjab S, Lallemend F

Nat Commun 9 (1) 3691 [2018-09-12; online 2018-09-12]

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Contribution of allelic imbalance to colorectal cancer.

Palin K, Pitkänen E, Turunen M, ..., Taipale J, Aaltonen LA

Nat Commun 9 (1) 3664 [2018-09-10; online 2018-09-10]

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Structural basis for endotoxin neutralisation and anti-inflammatory activity of thrombin-derived C-terminal peptides.

Saravanan R, Holdbrook DA, Petrlova J, ..., Malmsten M, Schmidtchen A

Nat Commun 9 (1) 2762 [2018-07-17; online 2018-07-17]

Structural Proteomics [Service]

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Spatial maps of prostate cancer transcriptomes reveal an unexplored landscape of heterogeneity

Berglund E, Maaskola J, Schultz N, ..., Helleday T, Lundeberg J

Nat Commun 9 (1) 2419 [2018-06-20; online 2018-06-20]

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Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.

Spåhr H, Chia T, Lingford JP, ..., Filipovska A, Rackham O

Nat Commun 9 (1) 2212 [2018-06-07; online 2018-06-07]

Protein Science Facility (PSF) [Service]

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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Davies G, Lam M, Harris SE, ..., Lencz T, Deary IJ

Nat Commun 9 (1) 2098 [2018-05-29; online 2018-05-29]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Repeated evolution of self-compatibility for reproductive assurance.

Nieuwenhuis BPS, Tusso S, Bjerling P, ..., Wolf JBW, Immler S

Nat Commun 9 (1) 1639 [2018-04-24; online 2018-04-24]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Rice auxin influx carrier OsAUX1 facilitates root hair elongation in response to low external phosphate.

Giri J, Bhosale R, Huang G, ..., Swarup R, Bennett MJ

Nat Commun 9 (1) 1408 [2018-04-12; online 2018-04-12]

Swedish Metabolomics Centre (SMC) [Service]

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A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.

Bhosale R, Giri J, Pandey BK, ..., Bennett MJ, Swarup R

Nat Commun 9 (1) 1409 [2018-04-12; online 2018-04-12]

Swedish Metabolomics Centre (SMC) [Service]

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A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.

Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S

Nat Commun 9 (1) 1107 [2018-03-16; online 2018-03-16]

Bioinformatics Support for Computational Resources [Service] Chemical Biology Consortium Sweden (CBCS) [Collaborative] Drug Discovery and Development (DDD) [Collaborative] Protein Science Facility (PSF) [Service]

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Genome-wide analysis yields new loci associating with aortic valve stenosis.

Helgadottir A, Thorleifsson G, Gretarsdottir S, ..., Holm H, Stefansson K

Nat Commun 9 (1) 987 [2018-03-07; online 2018-03-07]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.

Zhu Y, Orre LM, Johansson HJ, ..., Branca RMM, Lehtiö J

Nat Commun 9 (1) 903 [2018-03-02; online 2018-03-02]

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Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Jiang X, O'Reilly PF, Aschard H, ..., Kraft P, Kiel DP

Nat Commun 9 (1) 260 [2018-01-17; online 2018-01-17]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells.

Page BDG, Valerie NCK, Wright RHG, ..., Beato M, Helleday T

Nat Commun 9 (1) 250 [2018-01-17; online 2018-01-17]

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Reading and editing the Pleurodeles waltl genome reveals novel features of tetrapod regeneration.

Elewa A, Wang H, Talavera-López C, ..., Andersson B, Simon A

Nat Commun 8 (1) 2286 [2017-12-22; online 2017-12-22]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

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Mutational and putative neoantigen load predict clinical benefit of adoptive T cell therapy in melanoma

Lauss M, Donia M, Harbst K, ..., Svane IM, Jönsson G

Nat Commun 8 (1) - [2017-12-00; online 2017-11-23]

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The dynamic dimer structure of the chaperone Trigger Factor

Morgado L, Burmann BM, Sharpe T, Mazur A, Hiller S

Nat Commun 8 (1) - [2017-12-00; online 2017-12-08]

Swedish NMR Centre (SNC) [Service]

PubMed DOI Crossref

Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling

Petersen J, Wright SC, Rodríguez D, ..., Carlsson J, Schulte G

Nat Commun 8 (1) - [2017-12-00; online 2017-08-09]

Fluorescence Correlation Spectroscopy [Collaborative] Integrated Microscopy Technologies Stockholm [Service]

PubMed DOI Crossref

Brassinosteroid signaling-dependent root responses to prolonged elevated ambient temperature

Martins S, Montiel-Jorda A, Cayrel A, ..., Ljung K, Vert G

Nat Commun 8 (1) - [2017-12-00; online 2017-08-21]

Swedish Metabolomics Centre (SMC) [Service]

PubMed DOI Crossref

Structural basis for dolichylphosphate mannose biosynthesis

Gandini R, Reichenbach T, Tan TC, Divne C

Nat Commun 8 (1) - [2017-12-00; online 2017-07-25]

Protein Science Facility (PSF) [Service]

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A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family

Carreras-Puigvert J, Zitnik M, Jemth AS, ..., Zupan B, Helleday T

Nat Commun 8 (1) - [2017-12-00; online 2017-11-16]

BioImage Informatics [Collaborative] Drug Discovery and Development (DDD) [Collaborative] Protein Science Facility (PSF) [Service]

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Large-scale suppression of recombination predates genomic rearrangements in Neurospora tetrasperma

Sun Y, Svedberg J, Hiltunen M, Corcoran P, Johannesson H

Nat Commun 8 (1) - [2017-12-00; online 2017-10-26]

NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

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Microbial mineralization of cellulose in frozen soils.

Segura JH, Nilsson MB, Haei M, ..., Schleucher J, Öquist MG

Nat Commun 8 (1) 1154 [2017-10-27; online 2017-10-27]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Efficient protein production by yeast requires global tuning of metabolism.

Huang M, Bao J, Hallström BM, Petranovic D, Nielsen J

Nat Commun 8 (1) 1131 [2017-10-25; online 2017-10-25]

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The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus

Matzov D, Aibara S, Basu A, ..., Amunts A, Yonath AE

Nat Commun 8 (1) 723 [2017-09-28; online 2017-09-28]

Cryo-EM [Service]

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Synthetic lethality between androgen receptor signalling and the PARP pathway in prostate cancer.

Asim M, Tarish F, Zecchini HI, ..., Neal D, Helleday T

Nat Commun 8 (1) 374 [2017-08-29; online 2017-08-29]

Advanced FISH Technologies [Collaborative]

PubMed DOI Crossref

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Zillikens MC, Demissie S, Hsu YH, ..., Ohlsson C, Kiel DP

Nat Commun 8 (1) 80 [2017-07-19; online 2017-07-19]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Transancestral mapping and genetic load in systemic lupus erythematosus.

Langefeld CD, Ainsworth HC, Cunninghame Graham DS, ..., Gaffney PM, Vyse TJ

Nat Commun 8 (-) 16021 [2017-07-17; online 2017-07-17]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Nolte IM, Munoz ML, Tragante V, ..., Snieder H, de Geus EJC

Nat Commun 8 (-) 15805 [2017-06-14; online 2017-06-14]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Expression of CD226 is associated to but not required for NK cell education.

Wagner AK, Kadri N, Snäll J, ..., Kärre K, Chambers BJ

Nat Commun 8 (-) 15627 [2017-05-31; online 2017-05-31]

Cellular Immunomonitoring [Collaborative]

PubMed DOI Crossref

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Justice AE, Winkler TW, Feitosa MF, ..., North KE, Cupples LA

Nat Commun 8 (-) 14977 [2017-04-26; online 2017-04-26]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

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Light-sensing via hydrogen peroxide and a peroxiredoxin.

Bodvard K, Peeters K, Roger F, ..., Käll M, Molin M

Nat Commun 8 (1) 14791 [2017-03-24; online 2017-03-24]

Integrated Microscopy Technologies Gothenburg [Service]

PubMed DOI Crossref

Altered expression of maize PLASTOCHRON1 enhances biomass and seed yield by extending cell division duration

Sun X, Cahill J, Van Hautegem T, ..., Inzé D, Nelissen H

Nat Commun 8 (-) 14752 [2017-03-16; online 2017-03-16]

Swedish Metabolomics Centre (SMC) [Service]

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Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate.

Wahlestedt M, Erlandsson E, Kristiansen T, ..., Martin-Gonzalez J, Bryder D

Nat Commun 8 (-) 14533 [2017-02-22; online 2017-02-22]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

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Novel genetic loci associated with hippocampal volume.

Hibar DP, Adams HH, Jahanshad N, ..., Thompson PM, Ikram MA

Nat Commun 8 (-) 13624 [2017-01-18; online 2017-01-18]

Bioinformatics Support for Computational Resources [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

PubMed DOI Crossref

Production of individualized V gene databases reveals high levels of immunoglobulin genetic diversity.

Corcoran MM, Phad GE, Néstor VB, ..., Martin M, Karlsson Hedestam GB

Nat Commun 7 (-) 13642 [2016-12-20; online 2016-12-20]

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PubMed DOI Crossref

An oxygen-sensitive toxin-antitoxin system.

Marimon O, Teixeira JM, Cordeiro TN, ..., Wood TK, Pons M

Nat Commun 7 (-) 13634 [2016-12-08; online 2016-12-08]

Swedish NMR Centre (SNC) [Collaborative]

PubMed DOI Crossref

Evolution of heterogeneous genome differentiation across multiple contact zones in a crow species complex.

Vijay N, Bossu CM, Poelstra JW, ..., Kryukov AP, Wolf JB

Nat Commun 7 (1) 13195 [2016-10-31; online 2016-10-31]

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