Pilon M

Aging AdipoR2-deficient mice are hyperactive with enlarged brains excessively rich in saturated fatty acids.

Ruiz M, Devkota R, Bergh PO, ..., Borén J, Pilon M

FASEB J. 38 (14) e23815 [2024-07-31; online 2024-07-11]

Integrated Microscopy Technologies Gothenburg [Service]

Elevated Adipocyte Membrane Phospholipid Saturation Does Not Compromise Insulin Signaling.

Palmgren H, Petkevicius K, Bartesaghi S, ..., Peng XR, Pilon M

Diabetes 72 (10) 1350-1363 [2023-10-01; online 2022-12-30]

Integrated Microscopy Technologies Gothenburg [Service]

Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and embryogenesis.

Ruiz M, Devkota R, Panagaki D, ..., Borén J, Pilon M

Nat Commun 13 (1) 7162 [2022-11-22; online 2022-11-22]

Glycoproteomics and MS Proteomics [Service]

TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis

Petkevicius K, Palmgren H, Glover MS, ..., Maresca M, Peng XR

Nat Commun 13 (1) 6020 [2022-10-14; online 2022-10-14]

Swedish Metabolomics Centre (SMC) [Service]

A genetic titration of membrane composition in Caenorhabditis elegans reveals its importance for multiple cellular and physiological traits.

Devkota R, Kaper D, Bodhicharla R, ..., Borén J, Pilon M

Genetics 219 (1) - [2021-08-26; online 2021-06-15]

Integrated Microscopy Technologies Gothenburg [Service]

Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.

Busayavalasa K, Ruiz M, Devkota R, ..., Borén J, Pilon M

PLoS Genet. 16 (8) e1008975 [2020-08-00; online 2020-08-04]

Integrated Microscopy Technologies Gothenburg [Service]

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.

Ruiz M, Ståhlman M, Borén J, Pilon M

J. Lipid Res. 60 (5) 995-1004 [2019-05-00; online 2019-03-19]

Integrated Microscopy Technologies Gothenburg [Service]

Membrane fluidity is regulated by the C. elegans transmembrane protein FLD-1 and its human homologs TLCD1/2.

Ruiz M, Bodhicharla R, Svensk E, ..., Boren J, Pilon M

Elife 7 (-) - [2018-12-04; online 2018-12-04]

Integrated Microscopy Technologies Gothenburg [Service]

Membrane Fluidity Is Regulated Cell Nonautonomously by Caenorhabditiselegans PAQR-2 and Its Mammalian Homolog AdipoR2.

Bodhicharla R, Devkota R, Ruiz M, Pilon M

Genetics 210 (1) 189-201 [2018-09-00; online 2018-07-11]

Integrated Microscopy Technologies Gothenburg [Service]

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids.

Devkota R, Svensk E, Ruiz M, ..., Borén J, Pilon M

PLoS Genet. 13 (9) e1007004 [2017-09-00; online 2017-09-08]

Integrated Microscopy Technologies Gothenburg [Service]