Bioorg. Med. Chem. Lett.

Discovery of USP7 small-molecule allosteric inhibitors.

Engström O, Belda O, Kullman-Magnusson M, ..., Parkes KEB, Zhao H

Bioorg. Med. Chem. Lett. 30 (20) 127471 [2020-10-15; online 2020-08-08]

Swedish NMR Centre (SNC) [Service]

Profiling of in vitro activities of urea-based inhibitors against cysteine synthases from Mycobacterium tuberculosis.

Brunner K, Steiner EM, Reshma RS, ..., Schnell R, Schneider G

Bioorg. Med. Chem. Lett. 27 (19) 4582-4587 [2017-10-01; online 2017-08-19]

Chemical Biology Consortium Sweden (CBCS) [Service] Protein Science Facility (PSF) [Service]

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazines.

Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T

Bioorg. Med. Chem. Lett. 27 (16) 3897-3904 [2017-08-15; online 2017-06-16]

Drug Discovery and Development (DDD) [Collaborative]

Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.

Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T

Bioorg. Med. Chem. Lett. 27 (15) 3219-3225 [2017-08-01; online 2017-06-15]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Drug Discovery and Development (DDD) [Service]

Kinetic investigation of human 5-lipoxygenase with arachidonic acid.

Mittal M, Kumar RB, Balagunaseelan N, ..., Haeggström JZ, Rinaldo-Matthis A

Bioorg. Med. Chem. Lett. 26 (15) 3547-3551 [2016-08-01; online 2016-06-11]

Protein Science Facility (PSF) [Service]

Derivatives of 8-hydroxyquinoline--antibacterial agents that target intra- and extracellular Gram-negative pathogens.

Enquist P, Gylfe A, Hägglund U, ..., Sundin C, Elofsson M

Bioorg. Med. Chem. Lett. 22 (10) 3550-3553 [2012-05-15; online 2012-04-25]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]