Lundbäck T

Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound.

Giovannucci TA, Salomons FA, Haraldsson M, ..., Johnsen JI, Dantuma NP

Cell Death Dis 12 (10) 914 [2021-10-06; online 2021-10-06]

CRISPR Functional Genomics [Service] Chemical Biology Consortium Sweden (CBCS) [Collaborative] Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Design and development of a photoswitchable DFG-out kinase inhibitor.

Xu Y, Gao C, Håversen L, ..., Andréasson J, Grøtli M

Chem. Commun. (Camb.) 57 (78) 10043-10046 [2021-09-30; online 2021-09-30]

Chemical Biology Consortium Sweden (CBCS) [Service]

A FabG inhibitor targeting an allosteric binding site inhibits several orthologs from Gram-negative ESKAPE pathogens.

Vella P, Rudraraju RS, Lundbäck T, ..., Schneider G, Schnell R

Bioorg. Med. Chem. 30 (-) 115898 [2021-01-15; online 2020-12-05]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Development of a chemical probe against NUDT15.

Zhang SM, Desroses M, Hagenkort A, ..., Stenmark P, Helleday T

Nat. Chem. Biol. 16 (10) 1120-1128 [2020-10-00; online 2020-07-20]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Protein Science Facility (PSF) [Service]

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors.

Engen K, Vanga SR, Lundbäck T, ..., Larhed M, Rosenström U

ChemistryOpen 9 (3) 325-337 [2020-03-00; online 2020-03-02]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Perspective on CETSA Literature: Toward More Quantitative Data Interpretation.

Seashore-Ludlow B, Axelsson H, Lundbäck T

SLAS DISCOVERY: Advancing Life Sciences R&D 25 (2) 118-126 [2020-02-00; online 2019-10-30]

Chemical Biology Consortium Sweden (CBCS) [Technology development]

A Phenotypic Screening Assay Identifies Modulators of Diamond Blackfan Anemia.

Siva K, Ek F, Chen J, ..., Lundbäck T, Flygare J

SLAS DISCOVERY: Advancing Life Sciences R&D 24 (3) 304-313 [2019-03-00; online 2019-02-21]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Early Perspective: Microplate Applications of the Cellular Thermal Shift Assay (CETSA)

Seashore-Ludlow B, Lundbäck T

J Biomol Screen 21 (10) 1019-1033 [2016-12-00; online 2016-07-20]

Chemical Biology Consortium Sweden (CBCS) [Technology development]