Chorell E

Exploring the Dispersion and Electrostatic Components in Arene-Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands.

Andreasson M, Donzel M, Abrahamsson A, ..., Wanrooij S, Chorell E

J. Med. Chem. 67 (3) 2202-2219 [2024-02-08; online 2024-01-19]

Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells.

Doimo M, Chaudhari N, Abrahamsson S, ..., Chorell E, Wanrooij S

Nucleic Acids Res. 51 (14) 7392-7408 [2023-08-11; online 2023-06-23]

Clinical Genomics Gothenburg [Collaborative]

A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells.

Prasad B, Doimo M, Andréasson M, ..., Chorell E, Wanrooij S

Chem. Sci. 13 (8) 2347-2354 [2022-02-23; online 2022-02-01]

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures.

Deiana M, Obi I, Andreasson M, ..., Chorell E, Sabouri N

ACS Chem. Biol. 16 (8) 1365-1376 [2021-08-20; online 2021-07-30]

Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI).

Chorell E, Olsson T, Jansson JH, Wennberg P

Metabolites 11 (1) 25 [2020-12-31; online 2020-12-31]

Swedish Metabolomics Centre (SMC) [Service]

Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures.

Das RN, Andréasson M, Kumar R, Chorell E

Chem. Sci. 11 (38) 10529-10537 [2020-09-16; online 2020-09-16]

The Relation Between Position and Chemical Composition of Bis-Indole Substituents Determines Their Interactions with G-Quadruplex DNA.

Prasad B, Das RN, Jamroskovic J, ..., Sabouri N, Chorell E

Chemistry 26 (43) 9561-9572 [2020-08-03; online 2020-07-03]

A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA.

Deiana M, Chand K, Jamroskovic J, ..., Chorell E, Sabouri N

Nanoscale 12 (24) 12950-12957 [2020-06-25; online 2020-06-12]

Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes.

Kumar R, Chand K, Bhowmik S, ..., Hedenström M, Chorell E

Nucleic Acids Res. 48 (3) 1108-1119 [2020-02-20; online 2020-01-09]

Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization.

Jamroskovic J, Doimo M, Chand K, ..., Chorell E, Sabouri N

J. Am. Chem. Soc. 142 (6) 2876-2888 [2020-02-12; online 2020-01-28]

A Light-up Logic Platform for Selective Recognition of Parallel G-Quadruplex Structures via Disaggregation-Induced Emission.

Deiana M, Chand K, Jamroskovic J, ..., Chorell E, Sabouri N

Angew. Chem. Int. Ed. Engl. 59 (2) 896-902 [2020-01-07; online 2019-11-22]

Integrated Microscopy Technologies Umeå [Service]

Alterations in the metabolism of phospholipids, bile acids and branched-chain amino acids predicts development of type 2 diabetes in black South African women: a prospective cohort study.

Zeng Y, Mtintsilana A, Goedecke JH, ..., Olsson T, Chorell E

Metabolism 95 (-) 57-64 [2019-06-00; online 2019-04-04]

Swedish Metabolomics Centre (SMC) [Service]

Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNA

Livendahl M, Jamroskovic J, Hedenström M, ..., Sabouri N, Chorell E

Org. Biomol. Chem. 15 (15) 3265-3275 [2017-00-00; online 2017-00-00]

Identification of Compounds that Selectively Stabilize Specific G-Quadruplex Structures by Using a Thioflavin T-Displacement Assay as a Tool.

Jamroskovic J, Livendahl M, Eriksson J, Chorell E, Sabouri N

Chemistry 22 (52) 18932-18943 [2016-12-23; online 2016-11-20]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Design and Synthesis of 2,2'-Diindolylmethanes to Selectively Target Certain G-Quadruplex DNA Structures.

Livendahl M, Jamroskovic J, Ivanova S, ..., Sabouri N, Chorell E

Chemistry 22 (37) 13004-13009 [2016-09-05; online 2016-07-20]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Syntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activity.

Dang HT, Chorell E, Uvell H, ..., Hultgren SJ, Almqvist F

Org. Biomol. Chem. 12 (12) 1942-1956 [2014-03-28; online 2014-02-17]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]