J Immunother Cancer

Brain tumors induce immunoregulatory dendritic cells in draining lymph nodes that can be targeted by OX40 agonist treatment.

Badillo-Godinez O, Niemi J, Helfridsson L, ..., Nelander S, Hellström M

J Immunother Cancer 13 (5) - [2025-05-19; online 2025-05-19]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Dual molecule targeting HDAC6 leads to intratumoral CD4+ cytotoxic lymphocytes recruitment through MHC-II upregulation on lung cancer cells.

Ducellier S, Demeules M, Letribot B, ..., Nascimento M, Apcher S

J Immunother Cancer 12 (4) - [2024-04-11; online 2024-04-11]

Chemical Proteomics [Collaborative]

Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma.

Simonds EF, Lu ED, Badillo O, ..., Weiss WA, Hellström M

J Immunother Cancer 9 (6) - [2021-06-00; online 2021-06-05]

Bioinformatics Support for Computational Resources [Service]

In-depth plasma proteomics reveals increase in circulating PD-1 during anti-PD-1 immunotherapy in patients with metastatic cutaneous melanoma.

Babačić H, Lehtiö J, Pico de Coaña Y, Pernemalm M, Eriksson H

J Immunother Cancer 8 (1) e000204 [2020-05-00; online 2020-05-28]

Bioinformatics (NBIS) [Service] Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service]