Affinity Proteomics Uppsala

Platelet-Specific PDGFB Ablation Impairs Tumor Vessel Integrity and Promotes Metastasis.

Zhang Y, Cedervall J, Hamidi A, ..., Dimberg A, Olsson AK

Cancer Res. 80 (16) 3345-3358 [2020-08-15; online 2020-06-25]

Inflammatory markers in women with postpartum depressive symptoms.

Bränn E, Fransson E, White RA, ..., Sundström-Poromaa I, Skalkidou A

J Neuro Res 98 (7) 1309-1321 [2020-07-00; online 2018-09-05]

Affinity Proteomics Uppsala [Service] Bioinformatics Compute and Storage [Service] Clinical Biomarkers [Service]

Year 2019

Levels of caspase-3 and histidine-rich glycoprotein in the embryo secretome as biomarkers of good-quality day-2 embryos and high-quality blastocysts

Kaihola H, Yaldir FG, Bohlin T, ..., Hreinsson J, Åkerud H

PLoS ONE 14 (12) e0226419 [2019-12-19; online 2019-12-19]

Depression, GABA, and Age Correlate with Plasma Levels of Inflammatory Markers.

Bhandage AK, Cunningham JL, Jin Z, ..., Ekselius L, Birnir B

Int J Mol Sci 20 (24) 6172 [2019-12-06; online 2019-12-06]

Affinity Proteomics Uppsala [Collaborative]

Monitoring of Protein Biomarkers of Inflammation in Human Traumatic Brain Injury Using Microdialysis and Proximity Extension Assay Technology in Neurointensive Care.

Dyhrfort P, Shen Q, Clausen F, ..., Lewén A, Hillered L

J. Neurotrauma 36 (20) 2872-2885 [2019-10-15; online 2019-06-17]

Affinity Proteomics Uppsala [Technology development]

Reduced sialyl-Lewisx on salivary MUC7 from patients with burning mouth syndrome.

Acharya S, Jin C, Bylund J, ..., Carlén A, Karlsson NG

Mol Omics 15 (5) 331-339 [2019-10-07; online 2019-08-16]

Affinity Proteomics Uppsala [Collaborative] Glycoproteomics [Collaborative]

DOI Crossref

Combined mRNA and protein single cell analysis in a dynamic cellular system using SPARC

Reimegård J, Danielsson M, Tarbier M, ..., Friedländer MR, Gallant CJ

- - (-) - [2019-08-28; online 2019-08-28]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Compute and Storage [Service]

Profiling surface proteins on individual exosomes using a proximity barcoding assay.

Wu D, Yan J, Shen X, ..., Landegren U, Kamali-Moghaddam M

Nat Commun 10 (1) 3854 [2019-08-26; online 2019-08-26]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Compute and Storage [Service]

Multiplex plasma protein profiling identifies novel markers to discriminate patients with adenocarcinoma of the lung.

Djureinovic D, Pontén V, Landelius P, ..., Micke P, Ståhle E

BMC Cancer 19 (1) 741 [2019-07-29; online 2019-07-29]

Affinity Proteomics Uppsala [Collaborative] Bioinformatics Compute and Storage [Service] Clinical Biomarkers [Service]

TRAF6 function as a novel co-regulator of Wnt3a target genes in prostate cancer

Aripaka K, Gudey SK, Zang G, ..., von Hofsten J, Landström M

EBioMedicine 45 (-) 192-207 [2019-07-00; online 2019-07-00]

A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer.

Shen Q, Polom K, Williams C, ..., Roviello F, Kamali-Moghaddam M

EBioMedicine 44 (-) 322-333 [2019-06-00; online 2019-05-28]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Compute and Storage [Service] Clinical Biomarkers [Service] Glycoproteomics [Collaborative]

Protein measurements in venous plasma, earlobe capillary plasma and in plasma stored on filter paper.

Siart B, de Oliveira FMS, Shen Q, ..., Kamali-Moghaddam M, Wallner B

Anal. Biochem. 566 (-) 146-150 [2019-02-01; online 2018-11-22]

Affinity Proteomics Uppsala [Technology development]

Year 2018

Protein Profiling in Serum and Cerebrospinal Fluid Following Complex Surgery on the Thoracic Aorta Identifies Biological Markers of Neurologic Injury.

Lindblom RPF, Shen Q, Axén S, ..., Kamali-Moghaddam M, Thelin S

J. of Cardiovasc. Trans. Res. 11 (6) 503-516 [2018-12-00; online 2018-10-26]

Affinity Proteomics Uppsala [Collaborative] Bioinformatics Compute and Storage [Service]

Protein profiling of fine-needle aspirates reveals subtype-associated immune signatures and involvement of chemokines in breast cancer.

Franzén B, Alexeyenko A, Kamali-Moghaddam M, ..., Landegren U, Lewensohn R

Mol Oncol 13 (2) 376-391 [2018-11-19; online 2018-11-19]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Biomarkers [Service]

Upregulated BMP-Smad signaling activity in the glucuronyl C5-epimerase knock out MEF cells

Batool T, Fang J, Jansson V, ..., Moustakas A, Li JP

Cellular Signalling - (-) - [2018-11-00; online 2018-11-00]

Affinity Proteomics Uppsala [Collaborative]

VEGF receptor-2/neuropilin 1 trans-complex formation between endothelial and tumor cells is an independent predictor of pancreatic cancer survival

Morin E, Sjöberg E, Tjomsland V, ..., Sjöblom T, Claesson-Welsh L

J. Pathol 246 (3) 311-322 [2018-11-00; online 2018-09-04]

Affinity Proteomics Uppsala [Service] Bioinformatics Compute and Storage [Service]

Detection of post-translational modifications using solid-phase proximity ligation assay.

Oliveira FMS, Mereiter S, Lönn P, ..., Reis CA, Kamali-Moghaddam M

N Biotechnol 45 (-) 51-59 [2018-10-25; online 2017-10-31]

Affinity Proteomics Uppsala [Technology development] Glycoproteomics [Technology development]

Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes.

Palma M, Krstic A, Peña Perez L, ..., Månsson R, Smith CIE

Br. J. Haematol. 183 (2) 212-224 [2018-10-00; online 2018-08-20]

Affinity Proteomics Uppsala [Collaborative] Bioinformatics Compute and Storage [Service]

A fine-needle aspiration-based protein signature discriminates benign from malignant breast lesions

Franzén B, Kamali-Moghaddam M, Alexeyenko A, ..., Landegren U, Lewensohn R

Mol Oncol 12 (9) 1415-1428 [2018-09-00; online 2018-08-09]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Compute and Storage [Service] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Biomarkers [Service]

The endoplasmic reticulum-resident collagen chaperone Hsp47 interacts with and promotes the secretion of decorin, fibromodulin, and lumican.

Ishikawa Y, Rubin K, Bächinger HP, Kalamajski S

J. Biol. Chem. 293 (35) 13707-13716 [2018-08-31; online 2018-07-12]

CD93 promotes β1 integrin activation and fibronectin fibrillogenesis during tumor angiogenesis.

Lugano R, Vemuri K, Yu D, ..., Dejana E, Dimberg A

J. Clin. Invest. 128 (8) 3280-3297 [2018-08-01; online 2018-06-25]

Affinity Proteomics Uppsala [Service] Bioinformatics Compute and Storage [Service]

Plasma Protein Profiling Reveal Osteoprotegerin as a Marker of Prognostic Impact for Colorectal Cancer

Birgisson H, Tsimogiannis K, Freyhult E, Kamali-Moghaddam M

Transl Oncol 11 (4) 1034-1043 [2018-08-00; online 2018-08-00]

Affinity Proteomics Uppsala [Service] Bioinformatics Compute and Storage [Service] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Biomarkers [Service]

DOI Crossref

Human erythrocyte-derived nanovesicles can readily be loaded with doxorubicin and act as anticancer agents.

Dubois L, None , Löf L, ..., Ronquist G, Ronquist KG

Cancer Res Front 4 (1) 13-26 [2018-04-20; online 2018-04-20]

Affinity Proteomics Uppsala [Technology development]

GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4 + T Cells and Is Immunosuppressive in Type 1 Diabetes

Bhandage AK, Jin Z, Korol SV, ..., Kamali-Moghaddam M, Birnir B

EBioMedicine 30 (-) 283-294 [2018-04-00; online 2018-04-00]

Affinity Proteomics Uppsala [Collaborative] Bioinformatics Compute and Storage [Service] Clinical Biomarkers [Service]

Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes.

Klaesson A, Grannas K, Ebai T, ..., Söderberg O, Landegren U

Sci Rep 8 (1) 5400 [2018-03-29; online 2018-03-29]

Affinity Proteomics Uppsala [Technology development]

Strong impact on plasma protein profiles by precentrifugation delay but not by repeated freeze-thaw cycles, as analyzed using multiplex proximity extension assays.

Shen Q, Björkesten J, Galli J, ..., Tybring G, Landegren U

Clin. Chem. Lab. Med. 56 (4) 582-594 [2018-03-28; online 2017-10-19]

Affinity Proteomics Uppsala [Technology development]

Human Adenovirus Infection Causes Cellular E3 Ubiquitin Ligase MKRN1 Degradation Involving the Viral Core Protein pVII.

Inturi R, Mun K, Singethan K, Schreiner S, Punga T

J. Virol. 92 (3) - [2018-02-01; online 2018-01-17]

In situ protein detection with enhanced specificity using DNA-conjugated antibodies and proximity ligation.

Zieba A, Ponten F, Uhlén M, Landegren U

Mod. Pathol. 31 (2) 253-263 [2018-02-00; online 2017-09-22]

Affinity Proteomics Uppsala [Technology development] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Tissue Profiling [Collaborative]

Year 2017

Highly sensitive and specific protein detection via combined capillary isoelectric focusing and proximity ligation

Padhan N, Yan J, Boge A, ..., Claesson-Welsh L, Landegren U

Sci Rep 7 (1) - [2017-12-00; online 2017-05-04]

Affinity Proteomics Uppsala [Technology development]

Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.

Flowers SA, Zieba A, Örnros J, ..., Kamali-Moghaddam M, Karlsson NG

Sci Rep 7 (1) 13149 [2017-10-13; online 2017-10-13]

Affinity Proteomics Uppsala [Collaborative] Glycoproteomics [Collaborative]

Analytically Sensitive Protein Detection in Microtiter Plates by Proximity Ligation with Rolling Circle Amplification

Ebai T, Souza de Oliveira FM, Löf L, ..., Landegren U, Kamali-Moghaddam M

Clinical Chemistry 63 (9) 1497-1505 [2017-09-00; online 2017-06-30]

Affinity Proteomics Uppsala [Technology development]

Detection of Extracellular Vesicles Using Proximity Ligation Assay with Flow Cytometry Readout-ExoPLA.

Löf L, Arngården L, Ebai T, ..., Söderberg O, Kamali-Moghaddam M

Curr Protoc Cytom 81 (-) 4.8.1-4.8.10 [2017-07-05; online 2017-07-05]

Affinity Proteomics Uppsala [Technology development]

Stability of Proteins in Dried Blood Spot Biobanks

Björkesten J, Enroth S, Shen Q, ..., Kamali-Moghaddam M, Landegren U

Mol Cell Proteomics 16 (7) 1286-1296 [2017-07-00; online 2017-05-13]

Affinity Proteomics Uppsala [Technology development]

Close Encounters – Probing Proximal Proteins in Live or Fixed Cells

Lönn P, Landegren U

Trends in Biochemical Sciences 42 (7) 504-515 [2017-07-00; online 2017-07-00]

Affinity Proteomics Uppsala [Technology development]

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction

Edvinsson Å, Bränn E, Hellgren C, ..., Cunningham JL, Sundström-Poromaa I

Psychoneuroendocrinology 80 (-) 15-25 [2017-06-00; online 2017-06-00]

Affinity Proteomics Uppsala [Collaborative] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Biomarkers [Service]

Inflammatory markers in late pregnancy in association with postpartum depression-A nested case-control study.

Bränn E, Papadopoulos F, Fransson E, ..., Sundström-Poromaa I, Skalkidou A

Psychoneuroendocrinology 79 (-) 146-159 [2017-05-00; online 2017-02-28]

Affinity Proteomics Uppsala [Collaborative] Clinical Biomarkers [Service]

Structural Diversity of Human Gastric Mucin Glycans.

Jin C, Kenny DT, Skoog EC, ..., Lindén SK, Karlsson NG

Mol. Cell Proteomics 16 (5) 743-758 [2017-05-00; online 2017-05-04]

Affinity Proteomics Uppsala [Service] Glycoproteomics [Service]

Flow Cytometric Measurement of Blood Cells with BCR-ABL1 Fusion Protein in Chronic Myeloid Leukemia.

Löf L, Arngården L, Olsson-Strömberg U, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 7 (1) 623 [2017-04-04; online 2017-04-04]

Affinity Proteomics Uppsala [Technology development]

Revertant mosaicism repairs skin lesions in a patient with keratitis-ichthyosis-deafness syndrome by second-site mutations in connexin 26.

Gudmundsson S, Wilbe M, Ekvall S, ..., Törmä H, Bondeson ML

Hum. Mol. Genet. 26 (6) 1070-1077 [2017-03-15; online 2017-02-06]

Affinity Proteomics Uppsala [Service] Bioinformatics Compute and Storage [Service] Clinical Genomics Uppsala [Collaborative] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

Tracing Cellular Origin of Human Exosomes Using Multiplex Proximity Extension Assays

Larssen P, Wik L, Czarnewski P, ..., Gabrielsson S, Kamali-Moghaddam M

Mol Cell Proteomics 16 (3) 502-511 [2017-03-00; online 2017-01-22]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative]

Year 2016

Preclinical PET imaging of EGFR levels: pairing a targeting with a non-targeting Sel-tagged Affibody-based tracer to estimate the specific uptake.

Cheng Q, Wållberg H, Grafström J, ..., Ståhl S, Sel-tag imaging project

EJNMMI Res 6 (1) 58 [2016-12-00; online 2016-07-07]

Scaffolding protein IQGAP1: an insulin-dependent link between caveolae and the cytoskeleton in primary human adipocytes?

Jufvas A, Rajan MR, Jo nsson C, Stralfors P, Turkina MV

Biochemical Journal 473 (19) 3177-3188 [2016-10-01; online 2016-07-25]

Autoantibodies Targeting a Collecting Duct-Specific Water Channel in Tubulointerstitial Nephritis.

Landegren N, Pourmousa Lindberg M, Skov J, ..., Fenton RA, Kämpe O

J. Am. Soc. Nephrol. 27 (10) 3220-3228 [2016-10-00; online 2016-03-18]

Detecting individual extracellular vesicles using a multicolor in situ proximity ligation assay with flow cytometric readout.

Löf L, Ebai T, Dubois L, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 6 (1) 34358 [2016-09-29; online 2016-09-29]

Affinity Proteomics Uppsala [Technology development]

Multiplexed, targeted profiling of single-cell proteomes and transcriptomes in a single reaction.

Genshaft AS, Li S, Gallant CJ, ..., Landegren U, Shalek AK

Genome Biol. 17 (1) 188 [2016-09-19; online 2016-09-19]

Affinity Proteomics Uppsala [Technology development]

Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation

Watanabe Y, Papoutsoglou P, Maturi V, ..., Heldin CH, Moustakas A

J. Biol. Chem. 291 (24) 12706-12723 [2016-06-10; online 2016-04-21]

Detection of Biomarkers with Solid-Phase Proximity Ligation Assay in Patients with Colorectal Cancer

Ghanipour L, Darmanis S, Landegren U, ..., Påhlman L, Birgisson H

Transl Oncol 9 (3) 251-255 [2016-06-00; online 2016-06-00]

Affinity Proteomics Uppsala [Collaborative] Tissue Profiling [Service]

Single Chain Antibodies as Tools to Study transforming growth factor-β-Regulated SMAD Proteins in Proximity Ligation-Based Pharmacological Screens.

Blokzijl A, Zieba A, Hust M, ..., Dübel S, Landegren U

Mol. Cell Proteomics 15 (6) 1848-1856 [2016-06-00; online 2016-03-02]

Affinity Proteomics Uppsala [Technology development]

Inflammatory Serum Protein Profiling of Patients with Lumbar Radicular Pain One Year after Disc Herniation.

Moen A, Lind AL, Thulin M, ..., Gjerstad J, Gordh T

Int J Inflam 2016 (-) 3874964 [2016-05-11; online 2016-05-11]

Affinity Proteomics Uppsala [Collaborative] Clinical Biomarkers [Service]

Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay

Blokzijl A, Chen LE, Gustafsdottir SM, ..., Kamali-Moghaddam M, Hedstrand H

PLoS ONE 11 (4) e0154214 [2016-04-25; online 2016-04-25]

Affinity Proteomics Uppsala [Collaborative]

A Multiplex Protein Panel Applied to Cerebrospinal Fluid Reveals Three New Biomarker Candidates in ALS but None in Neuropathic Pain Patients

Lind AL, Wu D, Freyhult E, ..., Landegren U, Kamali-Moghaddam M

PLoS ONE 11 (2) e0149821 [2016-02-25; online 2016-02-25]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative]

Simultaneous Multiplexed Measurement of RNA and Proteins in Single Cells.

Darmanis S, Gallant CJ, Marinescu VD, ..., Westermark B, Landegren U

Cell Rep 14 (2) 380-389 [2016-01-12; online 2016-01-11]

Affinity Proteomics Uppsala [Technology development]

Year 2015

The body mass index (BMI) is significantly correlated with levels of cytokines and chemokines in cerebrospinal fluid

Larsson A, Carlsson L, Lind AL, ..., Kamali-Moghaddam M, Thulin M

Cytokine 76 (2) 514-518 [2015-12-00; online 2015-12-00]

Affinity Proteomics Uppsala [Collaborative] Clinical Biomarkers [Service]

The effects of age and gender on plasma levels of 63 cytokines

Larsson A, Carlsson L, Gordh T, ..., Thulin M, Kamali-Moghaddam M

Journal of Immunological Methods 425 (-) 58-61 [2015-10-00; online 2015-10-00]

Affinity Proteomics Uppsala [Collaborative] Clinical Biomarkers [Service]

Transglutaminase 4 as a prostate autoantigen in male subfertility.

Landegren N, Sharon D, Shum AK, ..., Snyder M, Kämpe O

Sci Transl Med 7 (292) 292ra101 [2015-06-17; online 2015-06-19]

Affinity Proteomics Uppsala Autoimmunity and Serology Profiling [Service] Bioinformatics Support and Infrastructure Bioinformatics Support, Infrastructure and Training

Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.

Gu Urban GJ, Friedman M, Ren P, ..., Landegren U, Kamali-Moghaddam M

Sci Rep 5 (1) 11196 [2015-06-16; online 2015-06-16]

Affinity Proteomics Uppsala [Technology development]

Proximity-dependent initiation of hybridization chain reaction.

Koos B, Cane G, Grannas K, ..., Kamali-Moghaddam M, Söderberg O

Nat Commun 6 (-) 7294 [2015-06-12; online 2015-06-12]

Affinity Proteomics Uppsala [Technology development]

Parallel protein detection by solid-phase proximity ligation assay with real-time PCR or sequencing.

Ebai T, Kamali-Moghaddam M, Landegren U

Curr Protoc Mol Biol 109 (-) 20.10.1-20.1025 [2015-01-05; online 2015-01-05]

Affinity Proteomics Uppsala [Technology development]

The Biobanking Analysis Resource Catalogue (BARCdb): a new research tool for the analysis of biobank samples.

Galli J, Oelrich J, Taussig MJ, ..., Ortega-Paino E, Landegren U

Nucleic Acids Res. 43 (Database issue) D1158-D1162 [2015-01-00; online 2014-10-23]

Year 2014

Sensitive detection of aggregated prion protein via proximity ligation.

Hammond M, Wik L, Deslys JP, ..., Landegren U, Kamali-Moghaddam M

Prion 8 (3) 261-265 [2014-12-09; online 2014-12-09]

Affinity Proteomics Uppsala [Technology development] Clinical Biomarkers

The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa.

Eriksson O, Ramström M, Hörnaeus K, ..., Mokhtari D, Siegbahn A

J. Biol. Chem. 289 (47) 32379-32391 [2014-11-21; online 2014-10-05]

A universal approach to prepare reagents for DNA-assisted protein analysis.

Yan J, Gu GJ, Jost C, ..., Landegren U, Kamali-Moghaddam M

PLoS ONE 9 (9) e108061 [2014-09-18; online 2014-09-18]

Affinity Proteomics Uppsala [Technology development] Clinical Biomarkers

Tyrosine phosphorylation profiling via in situ proximity ligation assay.

Elfineh L, Classon C, Asplund A, ..., Kamali-Moghaddam M, Lind SB

BMC Cancer 14 (-) 435 [2014-06-13; online 2014-06-13]

Protein biomarker validation via proximity ligation assays.

Blokzijl A, Nong R, Darmanis S, ..., Landegren U, Kamali-Moghaddam M

Biochim. Biophys. Acta 1844 (5) 933-939 [2014-05-00; online 2013-08-13]

Year 2013

A tosyl-activated magnetic bead cellulose as solid support for sensitive protein detection.

Yan J, Horák D, Lenfeld J, Hammond M, Kamali-Moghaddam M

J. Biotechnol. 167 (3) 235-240 [2013-09-10; online 2013-07-03]

Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

Gu GJ, Lund H, Wu D, ..., Sunnemark D, Kamali-Moghaddam M

Neuromolecular Med. 15 (3) 458-469 [2013-09-00; online 2013-05-12]

Affinity Proteomics Uppsala Clinical Biomarkers

Parallel visualization of multiple protein complexes in individual cells in tumor tissue.

Leuchowius KJ, Clausson CM, Grannas K, ..., Landegren U, Söderberg O

Mol. Cell Proteomics 12 (6) 1563-1571 [2013-06-00; online 2013-02-26]

Affinity Proteomics Uppsala NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure

Solid-phase proximity ligation assays for individual or parallel protein analyses with readout via real-time PCR or sequencing.

Nong RY, Wu D, Yan J, ..., Landegren U, Darmanis S

Nat Protoc 8 (6) 1234-1248 [2013-06-00; online 2013-05-30]

Dynamic gradients of an intermediate filament-like cytoskeleton are recruited by a polarity landmark during apical growth.

Fuchino K, Bagchi S, Cantlay S, ..., Flärdh K, Ausmees N

Proc. Natl. Acad. Sci. U.S.A. 110 (21) E1889-E1897 [2013-05-21; online 2013-05-04]

Offshoots of the ESF functional genomics programme.

Landegren U

N Biotechnol 30 (3) 296-298 [2013-03-25; online 2013-01-09]

Workshop on laboratory protocol standards for the Molecular Methods Database.

Klingström T, Soldatova L, Stevens R, ..., Landegren U, Bongcam-Rudloff E

N Biotechnol 30 (2) 109-113 [2013-01-25; online 2012-06-02]

Protein tag-mediated conjugation of oligonucleotides to recombinant affinity binders for proximity ligation.

Gu GJ, Friedman M, Jost C, ..., Landegren U, Söderberg O

N Biotechnol 30 (2) 144-152 [2013-01-25; online 2012-06-06]

Multiplex protein detection with DNA readout via mass spectrometry.

Flanigon J, Kamali-Moghaddam M, Burbulis I, ..., Landegren U, Cantor C

N Biotechnol 30 (2) 153-158 [2013-01-25; online 2012-12-04]

Year 2012

PCR-based multiparametric assays in single cells.

Darmanis S, Gallant C, Landegren U

Clin. Chem. 58 (12) 1618-1619 [2012-12-00; online 2012-10-17]

Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease.

Gu GJ, Wu D, Lund H, ..., Landegren U, Kamali-Moghaddam M

J. Alzheimers Dis. 33 (3) 699-713 [2012-09-25; online 2012-09-25]

Affinity Proteomics Uppsala Clinical Biomarkers

Molecular tools for companion diagnostics.

Zieba A, Grannas K, Söderberg O, ..., Nilsson M, Landegren U

N Biotechnol 29 (6) 634-640 [2012-09-15; online 2012-05-24]

Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.

Teranishi Y, Hur JY, Gu GJ, ..., Frykman S, Tjernberg LO

Biochem. Biophys. Res. Commun. 424 (3) 476-481 [2012-08-03; online 2012-07-10]

Profiling cellular protein complexes by proximity ligation with dual tag microarray readout.

Hammond M, Nong RY, Ericsson O, Pardali K, Landegren U

PLoS ONE 7 (7) e40405 [2012-07-10; online 2012-07-10]

Intercellular variation in signaling through the TGF-β pathway and its relation to cell density and cell cycle phase.

Zieba A, Pardali K, Söderberg O, ..., Heldin CH, Landegren U

Mol. Cell Proteomics 11 (7) M111.013482 [2012-07-00; online 2012-03-24]

Visualising individual sequence-specific protein-DNA interactions in situ.

Weibrecht I, Gavrilovic M, Lindbom L, ..., Wählby C, Söderberg O

N Biotechnol 29 (5) 589-598 [2012-06-15; online 2011-09-13]

Affinity Proteomics Uppsala BioImage Informatics [Collaborative]

Year 2011

Western blotting via proximity ligation for high performance protein analysis.

Liu Y, Gu J, Hagner-McWhirter Å, ..., Ivansson D, Landegren U

Mol. Cell Proteomics 10 (11) O111.011031 [2011-11-00; online 2011-08-02]

Increasing the dynamic range of in situ PLA.

Clausson C, Allalou A, Weibrecht I, ..., Wählby C, Söderberg O

Nat. Methods 8 (11) 892-893 [2011-10-28; online 2011-10-28]

Affinity Proteomics Uppsala BioImage Informatics [Collaborative]

ProteinSeq: high-performance proteomic analyses by proximity ligation and next generation sequencing.

Darmanis S, Nong RY, Vänelid J, ..., Kamali-Moghaddam M, Landegren U

PLoS ONE 6 (9) e25583 [2011-09-29; online 2011-09-29]

Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer.

Tavoosidana G, Ronquist G, Darmanis S, ..., Landegren UD, Kamali-Moghaddam M

Proc. Natl. Acad. Sci. U.S.A. 108 (21) 8809-8814 [2011-05-24; online 2011-05-11]

Affinity Proteomics Uppsala Clinical Biomarkers

Year 2010

Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease.

Kamali-Moghaddam M, Pettersson FE, Wu D, ..., Lannfelt L, Landegren U

BMC Neurosci 11 (-) 124 [2010-10-05; online 2010-10-05]

Profiling protein expression and interactions: proximity ligation as a tool for personalized medicine.

Blokzijl A, Friedman M, Pontén F, Landegren U

J. Intern. Med. 268 (3) 232-245 [2010-09-00; online 2010-08-11]

Sensitive plasma protein analysis by microparticle-based proximity ligation assays.

Darmanis S, Nong RY, Hammond M, ..., Landegren U, Kamali-Moghaddam M

Mol. Cell Proteomics 9 (2) 327-335 [2010-02-00; online 2009-12-04]