Immunity

Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies.

Pushparaj P, Nicoletto A, Sheward DJ, ..., Corcoran M, Karlsson Hedestam GB

Immunity 56 (1) 193-206.e7 [2023-01-10; online 2022-12-12]

Structural Proteomics [Collaborative]

Immunodeficiency syndromes differentially impact the functional profile of SARS-CoV-2-specific T cells elicited by mRNA vaccination.

Gao Y, Cai C, Wullimann D, ..., Aleman S, Buggert M

Immunity 55 (9) 1732-1746.e5 [2022-09-13; online 2022-07-19]

Bioinformatics Compute and Storage [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.

Glaros V, Rauschmeier R, Artemov AV, ..., Busslinger M, Kreslavsky T

Immunity 54 (9) 2005-2023.e10 [2021-09-14; online 2021-09-16]

Bioinformatics Compute and Storage [Service] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative]

Distinct developmental pathways from blood monocytes generate human lung macrophage diversity.

Evren E, Ringqvist E, Tripathi KP, ..., Villablanca EJ, Willinger T

Immunity 54 (2) 259-275.e7 [2021-02-09; online 2020-12-30]

Bioinformatics Compute and Storage [Service]

Immune Profiling of Human Gut-Associated Lymphoid Tissue Identifies a Role for Isolated Lymphoid Follicles in Priming of Region-Specific Immunity.

Fenton TM, Jørgensen PB, Niss K, ..., Johansson-Lindbom B, Agace WW

Immunity 52 (3) 557-570.e6 [2020-03-17; online 2020-03-10]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

A Call for Blood-In Human Immunology.

Brodin P, Duffy D, Quintana-Murci L

Immunity 50 (6) 1335-1336 [2019-06-18; online 2019-06-20]

Bioinformatics Compute and Storage [Service] Cellular Immunomonitoring [Technology development]

Single-Cell RNA Sequencing of the T Helper Cell Response to House Dust Mites Defines a Distinct Gene Expression Signature in Airway Th2 Cells

Tibbitt CA, Stark JM, Martens L, ..., Saeys Y, Coquet JM

Immunity 51 (1) 169-184.e5 [2019-06-00; online 2019-06-00]

Eukaryotic Single Cell Genomics (ESCG) [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Cellular Barcoding Links B-1a B Cell Potential to a Fetal Hematopoietic Stem Cell State at the Single-Cell Level.

Kristiansen TA, Jaensson Gyllenbäck E, Zriwil A, ..., Bryder D, Yuan J

Immunity 45 (2) 346-357 [2016-08-16; online 2016-08-18]

Bioinformatics Compute and Storage [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Powerful Populations Respond to Viruses and Vaccines.

Brodin P

Immunity 43 (6) 1035-1037 [2015-12-15; online 2015-12-20]

Cellular Immunomonitoring [Collaborative]