Chem. Sci.

Drug repurposing screens identify compounds that inhibit α-synuclein oligomers' membrane disruption and block antibody interactions

Somavarapu AK, Kleijwegt G, Nagaraj M, ..., Nielsen J, Otzen DE

Chem. Sci. 14 (11) 3030-3047 [2023-00-00; online 2023-00-00]

Chemical Biology Consortium Sweden (CBCS) [Service]

Ultrafast and selective labeling of endogenous proteins using affinity-based benzotriazole chemistry.

Xin X, Zhang Y, Gaetani M, ..., Corkery DP, Wu Y

Chem. Sci. 13 (24) 7240-7246 [2022-06-22; online 2022-05-30]

Chemical Proteomics [Service]

A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells.

Prasad B, Doimo M, Andréasson M, ..., Chorell E, Wanrooij S

Chem. Sci. 13 (8) 2347-2354 [2022-02-23; online 2022-02-01]

Swedish NMR Centre (SNC) [Service]

The structure of human dermatan sulfate epimerase 1 emphasizes the importance of C5-epimerization of glucuronic acid in higher organisms.

Hasan M, Khakzad H, Happonen L, ..., Malmström A, Tykesson E

Chem. Sci. 12 (5) 1869-1885 [2021-02-07; online 2020-12-08]

Structural Proteomics [Collaborative]

Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures.

Das RN, Andréasson M, Kumar R, Chorell E

Chem. Sci. 11 (38) 10529-10537 [2020-09-16; online 2020-09-16]

Swedish NMR Centre (SNC) [Service]