Shariatgorji R

Prosaposin maintains lipid homeostasis in dopamine neurons and counteracts experimental parkinsonism in rodents.

He Y, Kaya I, Shariatgorji R, ..., Andren PE, Svenningsson P

Nat Commun 14 (1) 5804 [2023-09-19; online 2023-09-19]

Spatial Mass Spectrometry [Collaborative]

On-Tissue Chemical Derivatization for Comprehensive Mapping of Brain Carboxyl and Aldehyde Metabolites by MALDI-MS Imaging.

Kaya I, Schembri LS, Nilsson A, ..., Odell LR, Andrén PE

J. Am. Soc. Mass Spectrom. 34 (5) 836-846 [2023-05-03; online 2023-04-13]

Spatial Mass Spectrometry [Technology development]

Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems.

Fridjonsdottir E, Vallianatou T, Mantas I, ..., Svenningsson P, Andrén PE

ACS Chem. Biol. 17 (1) 147-158 [2022-01-21; online 2021-12-21]

Spatial Mass Spectrometry [Technology development]

Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier.

Luptáková D, Vallianatou T, Nilsson A, ..., Loryan I, Andrén PE

Mol. Psychiatry - (-) - [2021-09-03; online 2021-09-03]

Spatial Mass Spectrometry [Technology development]

Spatial visualization of comprehensive brain neurotransmitter systems and neuroactive substances by selective in situ chemical derivatization mass spectrometry imaging.

Shariatgorji R, Nilsson A, Fridjonsdottir E, ..., Odell LR, Andrén PE

Nat Protoc 16 (7) 3298-3321 [2021-07-00; online 2021-06-02]

Spatial Mass Spectrometry [Technology development]

Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain.

Vallianatou T, Shariatgorji R, Nilsson A, ..., Svenningsson P, Andrén PE

ACS Chem Neurosci 12 (10) 1811-1823 [2021-05-19; online 2021-05-03]

Spatial Mass Spectrometry [Technology development]

Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA-induced dyskinesia.

Fridjonsdottir E, Shariatgorji R, Nilsson A, ..., Bezard E, Andrén PE

Sci Adv 7 (2) - [2021-01-00; online 2021-01-06]

Spatial Mass Spectrometry [Technology development]

Bromopyrylium Derivatization Facilitates Identification by Mass Spectrometry Imaging of Monoamine Neurotransmitters and Small Molecule Neuroactive Compounds.

Shariatgorji R, Nilsson A, Strittmatter N, ..., Goodwin RJA, Andrén PE

J. Am. Soc. Mass Spectrom. 31 (12) 2553-2557 [2020-12-02; online 2020-07-21]

Spatial Mass Spectrometry [Technology development]

Cross-validated Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging Quantitation Protocol for a Pharmaceutical Drug and Its Drug-Target Effects in the Brain Using Time-of-Flight and Fourier Transform Ion Cyclotron Resonance Analyzers.

Källback P, Vallianatou T, Nilsson A, ..., Svenningsson P, Andrén PE

Anal. Chem. 92 (21) 14676-14684 [2020-11-03; online 2020-10-21]

Spatial Mass Spectrometry [Technology development]