Zierath JR

Distinctive exercise-induced inflammatory response and exerkine induction in skeletal muscle of people with type 2 diabetes.

Pillon NJ, Smith JAB, Alm PS, ..., Krook A, Zierath JR

Sci Adv 8 (36) eabo3192 [2022-09-09; online 2022-09-07]

Spatial Proteomics [Service]

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A, Pillon NJ, ..., Loos RJF, Hoed Md

Nat. Genet. 54 (9) 1332-1344 [2022-09-00; online 2022-09-07]

NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

Impaired phosphocreatine metabolism in white adipocytes promotes inflammation.

Maqdasy S, Lecoutre S, Renzi G, ..., Mejhert N, Rydén M

Nat Metab 4 (2) 190-202 [2022-02-00; online 2022-02-14]

Swedish Metabolomics Centre (SMC) [Service]

Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.

Sjögren RJO, Rizo-Roca D, Chibalin AV, ..., Näslund E, Zierath JR

Diabetologia 64 (9) 2077-2091 [2021-09-00; online 2021-06-16]

Swedish Metabolomics Centre (SMC) [Service]

Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity.

Smith JAB, Savikj M, Sethi P, ..., Zierath JR, Näslund E

Am J Physiol Endocrinol Metab 321 (2) E203-E216 [2021-08-01; online 2021-06-21]

Swedish Metabolomics Centre (SMC) [Service]

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity.

Pillon NJ, Gabriel BM, Dollet L, ..., Krook A, Zierath JR

Nat Commun 11 (1) 470 [2020-01-24; online 2020-01-24]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service]