ACS Chem. Biol.

Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

Altincekic N, Jores N, Löhr F, ..., Sreeramulu S, Schwalbe H

ACS Chem. Biol. 19 (2) 563-574 [2024-02-16; online 2024-01-17]

Chemical Biology Consortium Sweden (CBCS) [Service] Swedish NMR Centre (SNC) [Collaborative]

Region-Specific and Age-Dependent Multitarget Effects of Acetylcholinesterase Inhibitor Tacrine on Comprehensive Neurotransmitter Systems.

Fridjonsdottir E, Vallianatou T, Mantas I, ..., Svenningsson P, Andrén PE

ACS Chem. Biol. 17 (1) 147-158 [2022-01-21; online 2021-12-21]

Spatial Mass Spectrometry [Technology development]

A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures.

Deiana M, Obi I, Andreasson M, ..., Chorell E, Sabouri N

ACS Chem. Biol. 16 (8) 1365-1376 [2021-08-20; online 2021-07-30]

Swedish NMR Centre (SNC) [Service]

Validating Signal Transducer and Activator of Transcription (STAT) Protein-Inhibitor Interactions Using Biochemical and Cellular Thermal Shift Assays.

Attarha S, Reithmeier A, Busker S, Desroses M, Page BDG

ACS Chem. Biol. 15 (7) 1842-1851 [2020-07-17; online 2020-07-02]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

Stabilized Cyclic Peptides as Scavengers of Autoantibodies: Neutralization of Anticitrullinated Protein/Peptide Antibodies in Rheumatoid Arthritis

Gunasekera S, Fernandes-Cerqueira C, Wennmalm S, ..., Jakobsson PJ, Göransson U

ACS Chem. Biol. 13 (6) 1525-1535 [2018-06-15; online 2018-04-09]

Bioinformatics Support for Computational Resources [Service] Integrated Microscopy Technologies Stockholm [Collaborative] Swedish NMR Centre (SNC) [Service]

In Situ Target Engagement Studies in Adherent Cells

Axelsson H, Almqvist H, Otrocka M, ..., Lundbäck T, Seashore-Ludlow B

ACS Chem. Biol. - (-) - [2018-02-21; online 2018-02-21]

Bioinformatics Support for Computational Resources [Service] Chemical Biology Consortium Sweden (CBCS) [Technology development]

Discovery of an allosteric inhibitor binding site in 3-Oxo-acyl-ACP reductase from Pseudomonas aeruginosa.

Cukier CD, Hope AG, Elamin AA, ..., Gray DW, Schneider G

ACS Chem. Biol. 8 (11) 2518-2527 [2013-11-15; online 2013-09-11]

Protein Science Facility (PSF)

PARP inhibitor with selectivity toward ADP-ribosyltransferase ARTD3/PARP3.

Lindgren AE, Karlberg T, Thorsell AG, ..., Elofsson M, Schüler H

ACS Chem. Biol. 8 (8) 1698-1703 [2013-08-16; online 2013-06-08]

Protein Science Facility (PSF)