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Publications
SciLifeLab National platform since 2013. Includes facilities ADME of Therapeautics, Biochemical and cellular screening, Biophysical Screening and Characterization, Human Antibody Therapeutics, In Vitro and Systems Pharmacology, Medicinal Chemistry – Hit2lead, Medicinal Chemistry – Lead Identification, Protein Expression and Characterization.
123 publications
Year 2020
Akaberi D, Krambrich J, Ling J, ..., Lennerstrand J, Lundkvist Å
Redox Biol 37 (-) 101734
[2020-12-02; online 2020-09-21]
Rendo V, Stoimenov I, Mateus A, ..., Cheong I, Sjöblom T
Nat Commun 11 (1) -
[2020-12-00; online 2020-03-11]
Preger C, Wigren E, Ossipova E, ..., Gräslund S, Persson H
pii: RA120.012893
pmc: PMC7549041
J. Biol. Chem. 295 (41) 13981-13993
[2020-10-09; online 2020-08-14]
Andersson CR, Selvin T, Blom K, ..., Nygren P, Larsson R
pii: 10.1038/s41598-020-68986-0
pmc: PMC7403428
Sci Rep 10 (1) 13124
[2020-08-04; online 2020-08-04]
Steinmetz J, Senkowski W, Lengqvist J, ..., Fryknäs M, Kultima K
ACS Omega 5 (28) 17242-17254
[2020-07-21; online 2020-07-06]
Johansson P, Krona C, Kundu S, ..., Marino S, Nelander S
pii: S2211-1247(20)30878-0
Cell Rep 32 (2) 107897
[2020-07-14; online 2020-07-16]
Montanuy H, Camps-Fajol C, Carreras-Puigvert J, ..., Minguillón J, Surrallés J
pii: 10.1186/s13023-020-01437-1
pmc: PMC7325660
Orphanet J Rare Dis 15 (1) 170
[2020-06-30; online 2020-06-30]
Saei AA, Gullberg H, Sabatier P, ..., Arnér ESJ, Zubarev RA
pii: S2213-2317(20)30243-3
pmc: PMC7082630
Redox Biol 32 (-) 101491
[2020-05-00; online 2020-03-03]
Popova G, Ladds MJGW, Johansson L, ..., Yngve U, Lain S
J. Med. Chem. 63 (8) 3915-3934
[2020-04-08; online 2020-04-08]
Opassi G, Nordström H, Lundin A, ..., Klebe G, Danielson UH
Protein Science 29 (4) 977-989
[2020-04-00; online 2020-02-07]
Eltahir M, Persson H, Mangsbo S
Expert Opin Biol Ther 20 (3) 215-217
[2020-03-00; online 2020-01-10]
Year 2019
Xu X, Makaraviciute A, Abdurakhmanov E, ..., Nyholm L, Zhang Z
ACS Sens. 5 (1) 217-224
[2019-12-23; online 2019-12-23]
Treyer A, Walday S, Boriss H, Matsson P, Artursson P
Pharm Res 36 (12) -
[2019-12-00; online 2019-11-07]
Filppula AM, Parvizi R, Mateus A, Baranczewski P, Artursson P
Sci Rep 9 (1) -
[2019-12-00; online 2019-04-10]
Xu X, Makaraviciute A, Kumar S, ..., Nyholm L, Zhang Z
Anal. Chem. 91 (22) 14697-14704
[2019-11-19; online 2019-10-25]
Niklasson M, Bergström T, Jarvius M, ..., Segerman B, Segerman A
J. Pathol. 249 (3) 295-307
[2019-11-00; online 2019-08-31]
Thota N, Makam P, Rajbongshi KK, ..., Naicker T, Arvidsson PI
ACS Med Chem Lett 10 (10) 1457-1461
[2019-10-10; online 2019-09-11]
Karlsson H, Senkowski W, Fryknäs M, ..., Larsson R, Nygren P
pii: 27166
pmc: PMC6731106
Oncotarget 10 (51) 5372-5382
[2019-09-03; online 2019-09-03]
Idborg H, Zandian A, Ossipova E, ..., Svenungsson E, Jakobsson PJ
Front Immunol 10 (-) -
[2019-05-17; online 2019-05-17]
Blom K, Rubin J, Berglund M, ..., Nygren P, Larsson R
pii: 10.1186/s13104-019-4273-5
pmc: PMC6477744
BMC Res Notes 12 (1) 234
[2019-04-22; online 2019-04-22]
Chinthakindi PK, Benediktsdottir A, Ibrahim A, ..., Chen Y, Sandström A
Eur. J. Org. Chem. 2019 (5) 1045-1057
[2019-02-07; online 2019-01-02]
Isaksson R, Lindman J, Wannberg J, ..., Gising J, Larhed M
ChemistryOpen 8 (1) 114-125
[2019-01-00; online 2019-01-24]
Kulén M, Núñez-Otero C, Cairns AG, ..., Gylfe Å, Almqvist F
Med. Chem. Commun. 10 (11) 1966-1987
[2019-00-00; online 2019-00-00]
Year 2018
Gustafsson NMS, Färnegårdh K, Bonagas N, ..., Olin T, Helleday T
Nat Commun 9 (1) -
[2018-12-00; online 2018-09-24]
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 9 (1) -
[2018-12-00; online 2018-03-16]
Islam MK, Strand M, Saleeb M, ..., Elofsson M, Evander M
Sci Rep 8 (1) -
[2018-12-00; online 2018-01-31]
Ladds MJGW, van Leeuwen IMM, Drummond CJ, ..., McCormack E, Laín S
Nat Commun 9 (1) -
[2018-12-00; online 2018-05-22]
Page BDG, Valerie NCK, Wright RHG, ..., Beato M, Helleday T
Nat Commun 9 (1) -
[2018-12-00; online 2018-01-17]
Visnes T, Cázares-Körner A, Hao W, ..., Boldogh I, Helleday T
Science 362 (6416) 834-839
[2018-11-16; online 2018-11-15]
Drobin K, Assadi G, Hong MG, ..., D’Amato M, Halfvarson J
- - (-) -
[2018-10-24; online 2018-10-24]
Chinthakindi PK, Arvidsson PI
Eur. J. Org. Chem. 2018 (27-28) 3648-3666
[2018-08-01; online 2018-07-06]
Skogh A, Lesniak A, Sköld C, ..., Hallberg M, Sandström A
Bioorganic & Medicinal Chemistry Letters 28 (14) 2446-2450
[2018-08-00; online 2018-08-00]
Sundell GN, Arnold R, Ali M, ..., Chi CN, Ivarsson Y
Mol. Syst. Biol. 14 (8) e8129
[2018-08-00; online 2018-08-20]
Rubin J, Mansoori S, Blom K, ..., Nygren P, Larsson R
pii: 25713
pmc: PMC6089388
Oncotarget 9 (56) 30805-30813
[2018-07-20; online 2018-07-20]
Persson H, Kirik U, Thörnqvist L, ..., Levander F, Ohlin M
Front Immunol 9 (-) -
[2018-06-21; online 2018-06-21]
Rossi Sebastiano M, Doak BC, Backlund M, ..., Matsson P, Kihlberg J
J. Med. Chem. 61 (9) 4189-4202
[2018-05-10; online 2018-04-02]
Ladds MJGW, Pastor-Fernández A, Popova G, ..., Bhatia R, Laín S
OSF: https://osf.io/sreqf/?view_only=bd0c5cd611be481984ef164d5d15df3d
PLoS ONE 13 (4) e0195956
[2018-04-23; online 2018-04-23]
Linkuvienė V, Talibov VO, Danielson UH, Matulis D
J. Med. Chem. 61 (6) 2292-2302
[2018-03-22; online 2018-02-21]
Costeira-Paulo J, Gault J, Popova G, ..., Marklund EG, Landreh M
Cell Chem Biol 25 (3) 309-317.e4
[2018-03-00; online 2018-03-00]
Säll A, Corbee D, Vikström S, ..., Persson H, Waldemarson S
PLoS ONE 13 (2) e0189116
[2018-02-13; online 2018-02-13]
Pettersson-Klein AT, Izadi M, Ferreira DMS, ..., Griffin PR, Ruas JL
Mol Metab - (-) -
[2018-02-00; online 2018-02-00]
Wannberg J, Isaksson R, Bremberg U, ..., Hallberg M, Larhed M
Bioorganic & Medicinal Chemistry Letters 28 (3) 519-522
[2018-02-00; online 2018-02-00]
Khumalo MF, Akpan ED, Chinthakindi PK, ..., Naicker T, Arvidsson PI
RSC Adv. 8 (65) 37503-37507
[2018-00-00; online 2018-00-00]
Peters BK, Razuwika R, Samipillai M, ..., Govender T, Naicker T
RSC Adv. 8 (1) 190-193
[2018-00-00; online 2018-00-00]
Year 2017
Nazir M, Senkowski W, Nyberg F, ..., Larsson R, Fryknäs M
pii: S0014-4827(17)30580-3
Exp. Cell Res. 361 (2) 308-315
[2017-12-15; online 2017-10-26]
Eriksson A, Chantzi E, Fryknäs M, ..., Höglund M, Larsson R
pii: S0145-2126(17)30565-9
Leuk Res 63 (-) 41-46
[2017-12-00; online 2017-10-28]
A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family
Carreras-Puigvert J, Zitnik M, Jemth AS, ..., Zupan B, Helleday T
Nat Commun 8 (1) -
[2017-12-00; online 2017-11-16]
Kashif M, Andersson C, Mansoori S, ..., Nygren P, Gustafsson MG
pii: 21895
pmc: PMC5732778
Oncotarget 8 (61) 103952-103967
[2017-11-28; online 2017-10-19]
Kirik U, Persson H, Levander F, Greiff L, Ohlin M
Front Immunol 8 (-) -
[2017-11-13; online 2017-11-13]
Arvidsson PI, Sandberg K, Sakariassen KS
Future Sci. OA 3(2), FSO176 (2) -
[2017-10-30; online 2017-04-07]
Ntshangase S, Shobo A, Kruger HG, ..., Govender T, Baijnath S
Xenobiotica - (-) 1-7
[2017-10-13; online 2017-10-13]
Skogh A, Lesniak A, Gaugaz FZ, ..., Hallberg M, Sandström A
pii: S0928-0987(17)30497-9
Eur J Pharm Sci 109 (-) 533-540
[2017-09-05; online 2017-09-05]
Karlgren M, Simoff I, Backlund M, ..., Oswald S, Artursson P
pii: S0022-3549(17)30251-4
J Pharm Sci 106 (9) 2909-2913
[2017-09-00; online 2017-04-24]
Skogh A, Lesniak A, Gaugaz FZ, ..., Hallberg M, Sandström A
pii: S0928-0987(17)30336-6
Eur J Pharm Sci 106 (-) 345-351
[2017-08-30; online 2017-06-03]
Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T
pii: S0960-894X(17)30640-6
Bioorg. Med. Chem. Lett. 27 (16) 3897-3904
[2017-08-15; online 2017-06-16]
Llona-Minguez S, Häggblad M, Martens U, ..., Scobie M, Helleday T
pii: S0960-894X(17)30641-8
Bioorg. Med. Chem. Lett. 27 (15) 3219-3225
[2017-08-01; online 2017-06-15]
Hu FJ, Volk AL, Persson H, ..., Uhlen M, Rockberg J
New Biotechnology - (-) -
[2017-08-00; online 2017-08-00]
Baijnath S, Moodley C, Ngcobo B, ..., Pym A, Govender T
International Journal of Antimicrobial Agents - (-) -
[2017-08-00; online 2017-08-00]
Blom K, Senkowski W, Jarvius M, ..., Nygren P, Larsson R
Immunopharmacol Immunotoxicol 39 (4) 199-210
[2017-08-00; online 2017-05-04]
Mdanda S, Baijnath S, Shobo A, ..., Naicker T, Govender T
Biomedical Chromatography - (-) e4035
[2017-07-13; online 2017-07-13]
Spahiu L, Ålander J, Ottosson-Wadlund A, ..., Armstrong RN, Morgenstern R
Biochemistry 56 (24) 3089-3098
[2017-06-20; online 2017-06-09]
Dutta J, Naicker T, Ebenhan T, ..., Arvidsson PI, Govender T
European Journal of Medicinal Chemistry 133 (-) 287-308
[2017-06-00; online 2017-06-00]
Llona-Minguez S, Höglund A, Ghassemian A, ..., Scobie M, Helleday T
J. Med. Chem. 60 (10) 4279-4292
[2017-05-25; online 2017-05-16]
Karlsson H, Fryknäs M, Strese S, ..., Larsson R, Nygren P
pii: 16324
pmc: PMC5444738
Oncotarget 8 (18) 30217-30234
[2017-05-02; online 2017-04-19]
Jiang Y, Marinescu VD, Xie Y, ..., Nelander S, Uhrbom L
pii: S2211-1247(17)30564-8
Cell Rep 19 (5) 1080-1081
[2017-05-02; online 2017-05-04]
Gad H, Koolmeister T, Jemth AS, ..., Scobie M, Ulrika Warpman Berglund &Thomas Helleday
pii: nature22083
Nature 544 (7651) 508
[2017-04-26; online 2017-04-28]
Chinthakindi PK, Naicker T, Thota N, ..., Kruger HG, Arvidsson PI
Angew. Chem. Int. Ed. 56 (15) 4100-4109
[2017-04-03; online 2017-02-23]
Llona-Minguez S, Höglund A, Wiita E, ..., Scobie M, Helleday T
J. Med. Chem. 60 (5) 2148-2154
[2017-03-09; online 2017-02-15]
Persson H, Preger C, Marcon E, Lengqvist J, Gräslund S
Methods Mol. Biol. 1575 (-) 175-187
[2017-03-04; online 2017-03-04]
Mateus A, Treyer A, Wegler C, ..., Matsson P, Artursson P
pii: srep43047
pmc: PMC5320532
Sci Rep 7 (-) 43047
[2017-02-22; online 2017-02-22]
Gustafsson R, Jemth A, Gustafsson NMS, ..., Helleday T, Stenmark P
pii: 0008-5472.CAN-16-1476
Cancer Res. 77 (4) 937-948
[2017-02-15; online 2016-12-03]
Chinthakindi PK, Govender KB, Kumar AS, ..., Naicker T, Arvidsson PI
Org. Lett. 19 (3) 480-483
[2017-02-03; online 2017-01-11]
Strese S, Hassan SB, Velander E, ..., Larsson R, Gullbo J
pii: 13856
pmc: PMC5351636
Oncotarget 8 (4) 6341-6352
[2017-01-24; online 2016-12-16]
Llona-Minguez S, Ghassemian A, Baranczewski P, ..., Scobie M, Helleday T
Med. Chem. Commun. 8 (7) 1553-1560
[2017-00-00; online 2017-00-00]
Year 2016
Segerman A, Niklasson M, Haglund C, ..., Segerman B, Westermark B
pii: S2211-1247(16)31629-1
Cell Rep 17 (11) 2994-3009
[2016-12-13; online 2016-12-16]
Fryknäs M, Zhang X, Bremberg U, ..., Linder S, Larsson R
pii: srep38343
pmc: PMC5141479
Sci Rep 6 (-) 38343
[2016-12-07; online 2016-12-07]
Warpman Berglund U, Sanjiv K, Gad H, ..., Scobie M, Helleday T
pii: mdw429
Ann. Oncol. 27 (12) 2275-2283
[2016-12-00; online 2016-11-08]
Advanced Mass Spectrometry Proteomics
[Collaborative]
Bioinformatics Support and Infrastructure
[Collaborative]
Bioinformatics Support, Infrastructure and Training
[Collaborative]
Chemical Biology Consortium Sweden (CBCS)
[Collaborative]
Chemical Proteomics
[Service]
Clinical Proteomics Mass spectrometry
[Collaborative]
Drug Discovery and Development (DDD)
[Collaborative]
Senkowski W, Jarvius M, Rubin J, ..., Larsson R, Fryknäs M
pii: S2451-9456(16)30353-1
Cell Chem Biol 23 (11) 1428-1438
[2016-11-17; online 2016-10-27]
Schmidt L, Baskaran S, Johansson P, ..., Krona C, Nelander S
pii: 12298
pmc: PMC5341973
Oncotarget 7 (45) 73200-73215
[2016-11-08; online 2016-10-01]
Orhan F, Bhat M, Sandberg K, ..., Erhardt S, Schwieler L
Scand. J. Immunol. 84 (5) 262-271
[2016-11-00; online 2016-10-27]
Diwakarla S, Nylander E, Grönbladh A, ..., Chai SY, Hallberg M
ACS Chem Neurosci 7 (10) 1383-1392
[2016-10-19; online 2016-08-08]
Renaud JP, Chung CW, Danielson UH, ..., Hubbard RE, Nar H
pii: nrd.2016.123
Nat Rev Drug Discov 15 (10) 679-698
[2016-10-00; online 2016-08-16]
Säll A, Walle M, Wingren C, ..., Borrebaeck CAK, Persson H
pii: gzw042
Protein Eng. Des. Sel. 29 (10) 427-437
[2016-10-00; online 2016-09-01]
Arvidsson PI, Sandberg K, Forsberg-Nilsson K
pii: S1359-6446(16)30244-6
Drug Discov. Today 21 (10) 1690-1698
[2016-10-00; online 2016-07-05]
Hammarström LG, Harmel RK, Granath M, ..., Lehmann F, Ernfors P
pii: 10.1021/acs.jmedchem.6b01009
J. Med. Chem. 59 (18) 8577-8592
[2016-09-22; online 2016-09-09]
Larsson MK, Faka A, Bhat M, ..., Schwieler L, Erhardt S
pii: 10.1007/s11064-016-1939-4
Neurochem. Res. 41 (9) 2243-2255
[2016-09-00; online 2016-05-12]
Thulin P, Bamberg K, Buler M, Dahl B, Glinghammar B
Int. J. Mol. Med. 38 (3) 961-968
[2016-09-00; online 2016-07-20]
Govender T, Arvidsson PI, Maguire GE, Kruger HG, Naicker T
Chem. Rev. 116 (16) 9375-9437
[2016-08-24; online 2016-07-28]
Neuroprotective potential of Linezolid: a quantitative and distribution study via mass spectrometry.
Baijnath S, Shobo A, Bester LA, ..., Naicker T, Govender T
pii: 10.1007/s10735-016-9685-0
J. Mol. Histol. 47 (4) 429-435
[2016-08-00; online 2016-06-22]
Engen K, Rosenström U, Axelsson H, ..., Lundbäck T, Larhed M
Assay Drug Dev Technol 14 (3) 180-193
[2016-04-00; online 2016-04-15]
Naicker T, Albericio F, Dutta J, ..., Kruger H, Govender T
Synlett 27 (11) 1685-1688
[2016-03-30; online 2016-03-30]
Chinthakindi PK, Kruger HG, Govender T, Naicker T, Arvidsson PI
J. Org. Chem. 81 (6) 2618-2623
[2016-03-18; online 2016-02-24]
Kinetically Selective Inhibitors of Human Carbonic Anhydrase Isozymes I, II, VII, IX, XII, and XIII.
Talibov VO, Linkuvienė V, Matulis D, Danielson UH
J. Med. Chem. 59 (5) 2083-2093
[2016-03-10; online 2016-01-26]
Isaksson R, Kumpiņa I, Larhed M, Wannberg J
Tetrahedron Letters 57 (13) 1476-1478
[2016-03-00; online 2016-03-00]
Naicker T, Arvidsson P, Chinthakindi P, ..., Govender T, Kruger H
Synlett 27 (09) 1423-1427
[2016-02-24; online 2016-02-24]
Kumpiņa I, Isaksson R, Sävmarker J, Wannberg J, Larhed M
Org. Process Res. Dev. 20 (2) 440-445
[2016-02-19; online 2016-02-19]
Llona-Minguez S, Höglund A, Jacques SA, ..., Scobie M, Helleday T
J. Med. Chem. 59 (3) 1140-1148
[2016-02-11; online 2016-02-11]
Makhathini SS, Das SK, Singh T, ..., Govender T, Naicker T
ARKIVOC 2016 (3) 134
[2016-02-07; online 2016-02-07]
Blom K, Nygren P, Alvarsson J, Larsson R, Andersson CR
pii: 2211068215598117
J Lab Autom 21 (1) 178-187
[2016-02-00; online 2015-08-05]
CHIWUNZE TE, Azumah R, Ramtahal M, ..., Govender T, Naicker T
S.Afr.j.chem. 69 (-) -
[2016-00-00; online 2016-00-00]
Year 2015
Shalaly ND, Aneiros E, Blank M, ..., Andersson CV, Sandberg K
J Biomol Screen 20 (9) 1112-1123
[2015-10-00; online 2015-10-00]
Wakchaure PB, Bremberg U, Wannberg J, Larhed M
Tetrahedron 71 (38) 6881-6887
[2015-09-00; online 2015-09-00]
Das SK, Bhatt N, Mujahid M, ..., Naicker T, Govender T
Tetrahedron Letters 56 (37) 5172-5174
[2015-09-00; online 2015-09-00]
Senkowski W, Zhang X, Olofsson MH, ..., Larsson R, Fryknäs M
pii: 1535-7163.MCT-14-0792
Mol Cancer Ther 14 (6) 1504-1516
[2015-06-00; online 2015-04-24]
Nandi GC, Kota SR, Naicker T, ..., Kruger HG, Arvidsson PI
Eur. J. Org. Chem. 2015 (13) 2861-2867
[2015-05-00; online 2015-03-17]
Somboro AM, Tiwari D, Bester LA, ..., Naicker T, Essack SY
J. Antimicrob. Chemother. 70 (5) 1594-1596
[2015-05-00; online 2015-01-06]
Aftab O, Fryknäs M, Hammerling U, Larsson R, Gustafsson MG
pii: 1087057114562158
J Biomol Screen 20 (3) 372-381
[2015-03-00; online 2014-12-17]
Strömberg K, Eketjäll S, Georgievska B, ..., Cowburn RF, Dabrowski M
FEBS J 282 (1) 65-73
[2015-01-00; online 2014-11-07]
Wakchaure PB, Borhade SR, Sandström A, Arvidsson PI
Eur. J. Org. Chem. 2015 (1) 213-219
[2015-01-00; online 2014-11-19]
Cele ZED, Arvidsson PI, Kruger HG, Govender T, Naicker T
Eur. J. Org. Chem. 2015 (3) 638-646
[2015-01-00; online 2014-12-11]
Nandi GC, Kota SR, Wakchaure PB, ..., Naicker T, Arvidsson PI
RSC Adv. 5 (76) 62084-62090
[2015-00-00; online 2015-00-00]
Md. Abdur Rauf S, Arvidsson PI, Albericio F, ..., Kruger HG, Honarparvar B
Org. Biomol. Chem. 13 (39) 9993-10006
[2015-00-00; online 2015-00-00]
Year 2014
Borhade SR, Rosenström U, Sävmarker J, ..., Larhed M, Hallberg M
ChemistryOpen 3 (6) 256-263
[2014-12-00; online 2014-11-21]
Nandi GC, Kota SR, Govender T, Kruger HG, Arvidsson PI
Tetrahedron 70 (35) 5428-5433
[2014-09-00; online 2014-09-00]
Khanyase S, Naicker T, Maguire GEM, ..., Arvidsson PI, Govender T
Tetrahedron: Asymmetry 25 (13-14) 969-973
[2014-07-00; online 2014-07-00]
Gad H, Koolmeister T, Jemth A, ..., Berglund UW, Helleday T
pii: nature13181
Nature 508 (7495) 215-221
[2014-04-10; online 2014-04-02]
Cele ZED, Pawar SA, Naicker T, ..., Kruger HG, Govender T
Eur. J. Org. Chem. 2014 (11) 2253-2260
[2014-04-00; online 2014-02-06]
Farahani MD, Honarparvar B, Albericio F, ..., Arvidsson PI, Kruger HG
Org. Biomol. Chem. 12 (25) 4479
[2014-00-00; online 2014-00-00]
Year 2013
Schmidt L, Kling T, Monsefi N, ..., Gerlee P, Nelander S
pii: not111
pmc: PMC3813417
Neuro-oncology 15 (11) 1469-1478
[2013-11-00; online 2013-10-06]
Johansson HJ, Sanchez BC, Mundt F, ..., Linderholm BK, Lehtiö J
pii: ncomms3175
pmc: PMC3759040
Nat Commun 4 (-) 2175
[2013-07-23; online 2013-07-23]