Glycoproteomics and MS Proteomics

Elucidating Thermothielavioides terrestris secretome changes for improved saccharification of mild steam-pretreated spruce.

Caputo F, Siaperas R, Dias C, Nikolaivits E, Olsson L

Biotechnol Biofuels Bioprod 17 (1) 127 [2024-10-05; online 2024-10-05]

Gilthead seabream mucus glycosylation is complex, differs between epithelial sites and carries unusual poly N-acetylhexosamine motifs.

Thomsson KA, Benktander J, Toxqui-Rodríguez S, Piazzon MC, Linden SK

Fish Shellfish Immunol. 153 (-) 109864 [2024-10-00; online 2024-08-30]

BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection.

Rajan A, Gallego P, Dolan B, ..., Simrén M, Pelaseyed T

Gut Microbes 16 (1) 2409247 [2024-09-30; online 2024-09-30]

Navigating the maze of mass spectra: a machine-learning guide to identifying diagnostic ions in O-glycan analysis.

Urban J, Joeres R, Thomès L, Thomsson KA, Bojar D

Anal Bioanal Chem - (-) - [2024-08-24; online 2024-08-24]

Surface-Shaving of Staphylococcus aureus Strains and Quantitative Proteomic Analysis Reveal Differences in Protein Abundance of the Surfaceome.

Karlsson A, Alarcón LA, Piñeiro-Iglesias B, ..., Jin T, Karlsson R

Microorganisms 12 (8) - [2024-08-21; online 2024-08-21]

Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Service]

The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.

Swisa A, Kieckhaefer J, Daniel SG, ..., Bittinger K, Kaestner KH

Dev. Cell 59 (16) 2069-2084.e8 [2024-08-19; online 2024-05-30]

Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron.

Schaus SR, Vasconcelos Pereira G, Luis AS, ..., Hansson GC, Martens EC

MBio 15 (8) e0003924 [2024-08-14; online 2024-07-08]

Normoglycemia and physiological cortisone level maintain glucose homeostasis in a pancreas-liver microphysiological system.

Rigal S, Casas B, Kanebratt KP, ..., Andersson TB, Vilén LK

Commun Biol 7 (1) 877 [2024-07-18; online 2024-07-18]

Suppression of the Escherichia coli rnpA49 conditionally lethal phenotype by different compensatory mutations.

Babina AM, Kirsebom LA, Andersson DI

RNA 30 (8) 977-991 [2024-07-16; online 2024-07-16]

UniCarb-DB: An MS/MS Experimental Glycomic Fragmentation Database.

Jin C, Venkatakrishnan V, Thomsson KA, ..., Lisacek F, Karlsson NG

Methods Mol. Biol. 2836 (-) 77-96 [2024-07-12; online 2024-07-12]

Predicting glycan structure from tandem mass spectrometry via deep learning.

Urban J, Jin C, Thomsson KA, ..., Fadda E, Bojar D

Nat. Methods 21 (7) 1206-1215 [2024-07-00; online 2024-07-01]

Metaproteomics reveals parallel utilization of colonic mucin glycans and dietary fibers by the human gut microbiota.

Raba G, Luis AS, Schneider H, ..., Adamberg K, Arike L

iScience 27 (6) 110093 [2024-06-21; online 2024-05-23]

Integrative transcriptomic and proteomic profiling of the effects of cell confluency on gene expression.

Lobo V, Shcherbinina E, Westholm JO, ..., Anastasakis DG, Sarshad AA

Sci Data 11 (1) 617 [2024-06-12; online 2024-06-12]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Glycoproteomics and MS Proteomics [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Effect of an endothelial regulatory module on plasma proteomics in exercising horses.

Amiri Roudbar M, Rosengren MK, Mousavi SF, ..., Meadows JRS, Lindgren G

Comp Biochem Physiol Part D Genomics Proteomics 52 (-) 101265 [2024-06-06; online 2024-06-06]

Proteomics of cell-free breast cancer scaffolds identify clinically relevant imprinted proteins and cancer-progressing properties.

Gustafsson A, Jonasson E, Ståhlberg A, Landberg G

Cancer Commun (Lond) 44 (6) 695-699 [2024-06-00; online 2024-04-04]

Proteomic profiling of polyglucosan bodies associated with glycogenin-1 deficiency in skeletal muscle.

Visuttijai K, Hedberg-Oldfors C, Costello DJ, Bermingham N, Oldfors A

Neuropathol Appl Neurobiol 50 (3) e12995 [2024-06-00; online 2024-06-26]

Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

A monoallelic UXS1 variant associated with short-limbed short stature.

Rustad CF, Backe PH, Jin C, ..., Elgstøen KBP, Holla ØL

Mol Genet Genomic Med 12 (6) e2472 [2024-06-00; online 2024-06-11]

Local Immune Activation and Age Impact on Humoral Immunity in Mice, with a Focus on IgG Sialylation.

Gupta P, Sághy T, Bollmann M, ..., Corciulo C, Engdahl C

Vaccines (Basel) 12 (5) - [2024-04-29; online 2024-04-29]

Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development.

Ranji P, Jonasson E, Andersson L, ..., Åman P, Ståhlberg A

J Transl Med 22 (1) 389 [2024-04-26; online 2024-04-26]

Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Service]

N-glycoproteomic analyses of human intestinal enteroids, varying in histo-blood group geno- and phenotypes, reveal a wide repertoire of fucosylated glycoproteins.

Nilsson J, Rimkute I, Sihlbom C, ..., Estes MK, Larson G

Glycobiology 34 (6) - [2024-04-24; online 2024-04-09]

Expression of influenza A virus glycan receptor candidates in mallard, chicken, and tufted duck.

Nilsson J, Eriksson P, Naguib MM, ..., Larson G, Ellström P

Glycobiology 34 (3) - [2024-04-01; online 2023-12-21]

Bioinformatics Support, Infrastructure and Training [Collaborative] Glycoproteomics and MS Proteomics [Collaborative]

Ion mobility-tandem mass spectrometry of mucin-type O-glycans.

Bechtella L, Chunsheng J, Fentker K, ..., Karlsson NG, Pagel K

Nat Commun 15 (1) 2611 [2024-03-23; online 2024-03-23]

Ischemic preconditioning affects phosphosites and accentuates myocardial stunning while reducing infarction size in rats.

Elmahdy A, Shekka Espinosa A, Kakaei Y, ..., Hussain S, Redfors B

Front Cardiovasc Med 11 (-) 1376367 [2024-03-15; online 2024-03-15]

Characterization of intestinal O-glycome in reactive oxygen species deficiency.

Saldova R, Thomsson KA, Wilkinson H, ..., Karlsson NG, Knaus UG

PLoS ONE 19 (3) e0297292 [2024-03-14; online 2024-03-14]

Aberrant MNX1 expression associated with t(7;12)(q36;p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation.

Waraky A, Östlund A, Nilsson T, ..., Plass C, Palmqvist L

Haematologica 109 (3) 725-739 [2024-03-01; online 2024-03-01]

Staphylococcus aureus mutants resistant to the feed-additive monensin show increased virulence and altered purine metabolism.

Warsi OM, Upterworth LM, Breidenstein A, ..., Ingmer H, Andersson DI

MBio 15 (2) e0315523 [2024-02-14; online 2024-01-12]

The role of extracellular vesicle fusion with target cells in triggering systemic inflammation.

Papareddy P, Tapken I, Kroh K, ..., Holub M, Herwald H

Nat Commun 15 (1) 1150 [2024-02-07; online 2024-02-07]

A macrophage-collagen fragment axis mediates subcutaneous adipose tissue remodeling in mice.

Vujičić M, Broderick I, Salmantabar P, ..., Sihlbom Wallem C, Wernstedt Asterholm I

Proc. Natl. Acad. Sci. U.S.A. 121 (6) e2313185121 [2024-02-06; online 2024-02-01]

Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion.

Sharma H, Jespersen N, Ehrenbolger K, Carlson LA, Barandun J

PLoS Biol. 22 (2) e3002533 [2024-02-00; online 2024-02-29]

Cryo-EM [Service] Glycoproteomics and MS Proteomics [Service]

MiCId GUI: The Graphical User Interface for MiCId, a Fast Microorganism Classification and Identification Workflow with Accurate Statistics and High Recall.

Ogurtsov A, Alves G, Rubio A, ..., Moore ERB, Yu YK

J Comput Biol 31 (2) 175-178 [2024-02-00; online 2024-02-02]

Clinical Genomics Gothenburg [Collaborative] Glycoproteomics and MS Proteomics [Service]

Glycoproteomic profile of human tissue-nonspecific alkaline phosphatase expressed in osteoblasts.

Atanasova D, Mirgorodskaya E, Moparthi L, ..., Landberg E, Magnusson P

JBMR Plus 8 (2) ziae006 [2024-02-00; online 2024-01-22]

Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis.

Leo F, Lood R, Thomsson KA, ..., Svensäter G, Wickström C

Front Microbiol 15 (-) 1340109 [2024-01-18; online 2024-01-18]

Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS.

Stener-Victorin E, Eriksson G, Mohan Shrestha M, ..., Lanner J, Benrick A

Elife 12 (-) - [2024-01-05; online 2024-01-05]

Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model.

Samad M, Ek J, Börchers S, ..., Asterholm IW, Benrick A

Sci Rep 14 (1) 563 [2024-01-04; online 2024-01-04]

Heat inactivation of foetal bovine serum performed after EV-depletion influences the proteome of cell-derived extracellular vesicles.

Urzì O, Bergqvist M, Lässer C, ..., Olofsson Bagge R, Crescitelli R

J Extracell Vesicles 13 (1) e12408 [2024-01-00; online 2024-01-24]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Year 2023

Proteomic profiles associated with postsurgical progression in non-functioning pituitary adenomas.

Hallén T, Johannsson G, Thorsell A, ..., Bergquist J, Skoglund T

J. Clin. Endocrinol. Metab. - (-) - [2023-12-29; online 2023-12-29]

Glycan Complexity and Heterogeneity of Glycoproteins in Somatic Extracts and Secretome of the Infective Stage of the Helminth Fasciola hepatica.

De Marco Verissimo C, Cwiklinski K, Nilsson J, ..., Karlsson NG, Dalton JP

Mol. Cell Proteomics 22 (12) 100684 [2023-12-00; online 2023-11-21]

Calmodulin regulates protease versus co-chaperone activity of a metacaspase.

Eisele-Bürger AM, Eisele F, Malmgren Hill S, ..., Bozhkov PV, Nyström T

Cell Rep 42 (11) 113372 [2023-11-28; online 2023-11-08]

TGF-β induces matrisome pathological alterations and EMT in patient-derived prostate cancer tumoroids.

Fernandes S, Cruz JO, Morazzo S, ..., Filipensky P, Forte G

Matrix Biol. - (-) - [2023-11-07; online 2023-11-07]

A glycomic workflow for LC-MS/MS analysis of urine glycosaminoglycan biomarkers in mucopolysaccharidoses.

Nilsson J, Persson A, Vorontsov E, ..., Larson G, Blomqvist M

Glycoconj J 40 (5) 523-540 [2023-10-00; online 2023-07-18]

Identification of Novel Glycans in the Mucus Layer of Shark and Skate Skin.

Bachar-Wikstrom E, Thomsson KA, Sihlbom C, ..., Lindén SK, Wikstrom JD

Int J Mol Sci 24 (18) - [2023-09-20; online 2023-09-20]

Impact of estrogen on IgG glycosylation and serum protein glycosylation in a murine model of healthy postmenopause.

Gupta P, Sághy T, Nordqvist J, ..., Henning P, Engdahl C

Front Endocrinol (Lausanne) 14 (-) 1243942 [2023-09-11; online 2023-09-11]

Quantification of chondroitin sulfate, hyaluronic acid and N-glycans in synovial fluid - A technical performance study.

Andersson E, Tykesson E, Lohmander LS, ..., Swärd P, Struglics A

Osteoarthr Cartil Open 5 (3) 100380 [2023-09-00; online 2023-06-10]

Breast Milk Oligosaccharides Contain Immunomodulatory Glucuronic Acid and LacdiNAc.

Jin C, Lundstrøm J, Korhonen E, Luis AS, Bojar D

Mol. Cell Proteomics 22 (9) 100635 [2023-09-00; online 2023-08-18]

STE20-type kinases MST3 and MST4 promote the progression of hepatocellular carcinoma: Evidence from human cell culture and expression profiling of liver biopsies.

Caputo M, Xia Y, Anand SK, ..., Peter A, Mahlapuu M

FASEB J. 37 (8) e23105 [2023-08-00; online 2023-07-25]

Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.

Noborn F, Nilsson J, Sihlbom C, ..., Kjellén L, Larson G

Mol. Cell Proteomics 22 (8) 100617 [2023-08-00; online 2023-07-14]

Low-grade intestinal inflammation two decades after pelvic radiotherapy.

Devarakonda S, Thorsell A, Hedenström P, ..., Steineck G, Bull C

EBioMedicine 94 (-) 104691 [2023-08-00; online 2023-07-20]

Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Collaborative]

Proteomics identifies lipocalin-2 in neonatal inflammation associated with cerebrovascular alteration in mice and preterm infants.

Gravina G, Ardalan M, Chumak T, ..., Hellström A, Mallard C

iScience 26 (7) 107217 [2023-07-21; online 2023-06-27]

AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity.

Ruiz M, Devkota R, Kaper D, ..., Borén J, Pilon M

J. Biol. Chem. 299 (6) 104799 [2023-06-00; online 2023-05-08]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Cisplatin toxicity is counteracted by the activation of the p38/ATF-7 signaling pathway in post-mitotic C. elegans.

Raj D, Kraish B, Martikainen J, ..., Kao G, Naredi P

Nat Commun 14 (1) 2886 [2023-05-20; online 2023-05-20]

Clinical Genomics Gothenburg [Collaborative] Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Detoxified synthetic bacterial membrane vesicles as a vaccine platform against bacteria and SARS-CoV-2.

Park KS, Svennerholm K, Crescitelli R, ..., Farewell A, Lötvall J

J Nanobiotechnology 21 (1) 156 [2023-05-19; online 2023-05-19]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Divergent and dominant anti-inflammatory effects of patient-derived anticitrullinated protein antibodies (ACPA) in arthritis development.

Raposo B, Afonso M, Israelsson L, ..., Klareskog L, Malmström V

Ann. Rheum. Dis. 82 (5) 724-726 [2023-05-00; online 2023-01-05]

Sialidases and fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria.

Shuoker B, Pichler MJ, Jin C, ..., Karlsson NG, Abou Hachem M

Nat Commun 14 (1) 1833 [2023-04-01; online 2023-04-01]

Lung macrophages utilize unique cathepsin K-dependent phagosomal machinery to degrade intracellular collagen.

Fabrik I, Bilkei-Gorzo O, Öberg M, ..., Göransson M, Härtlova A

Life Sci. Alliance 6 (4) - [2023-04-00; online 2023-01-25]

Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility.

Cinato M, Mardani I, Miljanovic A, ..., Borén J, Levin MC

Life Sci. Alliance 6 (4) - [2023-04-00; online 2023-01-30]

A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans.

Podraza-Farhanieh A, Raj D, Kao G, Naredi P

Development 150 (6) - [2023-03-15; online 2023-03-20]

Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Subtyping of cardiac amyloidosis by mass spectrometry-based proteomics of endomyocardial biopsies.

Noborn F, Thomsen C, Vorontsov E, ..., Oldfors A, Larson G

Amyloid 30 (1) 96-108 [2023-03-00; online 2022-10-09]

Isobaric labeling-based quantitative proteomics of FACS-purified immune cells and epithelial cells from the intestine of Crohn's disease patients reveals proteome changes of potential importance in disease pathogenesis.

Alfredsson J, Fabrik I, Gorreja F, ..., Lindskog EB, Wick MJ

Proteomics 23 (5) e2200366 [2023-03-00; online 2022-12-25]

Increasing Complexity of the N-Glycome During Caenorhabditis Development.

Wilson IBH, Yan S, Jin C, ..., Schnabel R, Paschinger K

Mol. Cell Proteomics 22 (3) 100505 [2023-03-00; online 2023-01-28]

Comprehensive characterization of complex glycosphingolipids in human pancreatic cancer tissues.

Hořejší K, Jin C, Vaňková Z, ..., Teneberg S, Holčapek M

J. Biol. Chem. 299 (3) 102923 [2023-03-00; online 2023-01-19]

Reproducing extracellular matrix adverse remodelling of non-ST myocardial infarction in a large animal model.

Contessotto P, Spelat R, Ferro F, ..., Pandit A, Da Costa M

Nat Commun 14 (1) 995 [2023-02-22; online 2023-02-22]

Responses of carbapenemase-producing and non-producing carbapenem-resistant Pseudomonas aeruginosa strains to meropenem revealed by quantitative tandem mass spectrometry proteomics.

Salvà-Serra F, Jaén-Luchoro D, Marathe NP, ..., Moore ERB, Karlsson R

Front Microbiol 13 (-) 1089140 [2023-02-09; online 2023-02-09]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Service]

Year 2022

Metataxonomic and metaproteomic profiling of the oral microbiome in oral lichen planus - a pilot study.

Bankvall M, Carda-Diéguez M, Mira A, ..., Karlsson R, Robledo-Sierra J

Journal of Oral Microbiology 15 (1) 2161726 [2022-12-28; online 2022-12-28]

<i>Aeromonas salmonicida</i> binds α2-6 linked sialic acid, which is absent among the glycosphingolipid repertoires from skin, gill, stomach, pyloric caecum, and intestine.

Benktander J, Sundh H, Sharba S, Teneberg S, Lindén SK

Virulence 13 (1) 1741-1751 [2022-12-00; online 2022-10-08]

The mechanical regulation of RNA binding protein hnRNPC in the failing heart.

Martino F, Varadarajan NM, Perestrelo AR, ..., Pagliari S, Forte G

Sci Transl Med 14 (672) eabo5715 [2022-11-23; online 2022-11-23]

Sphingosine 1-phosphate mediates adiponectin receptor signaling essential for lipid homeostasis and embryogenesis.

Ruiz M, Devkota R, Panagaki D, ..., Borén J, Pilon M

Nat Commun 13 (1) 7162 [2022-11-22; online 2022-11-22]

Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturation.

Gaur D, Kumar N, Ghosh A, ..., Nystrom T, Sharma D

PLoS Genet. 18 (11) e1010442 [2022-11-00; online 2022-11-09]

A Complex Connection Between the Diversity of Human Gastric Mucin O-Glycans, Helicobacter pylori Binding, Helicobacter Infection and Fucosylation.

Chahal G, Padra M, Erhardsson M, ..., Karlsson NG, Lindén SK

Mol. Cell Proteomics 21 (11) 100421 [2022-11-00; online 2022-09-29]

Global microRNA and protein expression in human term placenta.

Östling H, Lodefalk M, Backman H, Kruse R

Front Med (Lausanne) 9 (-) 952827 [2022-10-18; online 2022-10-18]

Targeting Myd88 using peptide-loaded mesenchymal stem cell membrane-derived synthetic vesicles to treat systemic inflammation.

Park KS, Bergqvist M, Lässer C, Lötvall J

J Nanobiotechnology 20 (1) 451 [2022-10-15; online 2022-10-15]

Liver Graft Proteomics Reveals Potential Incipient Mechanisms behind Early Renal Dysfunction after Liver Transplantation.

Norén Å, Oltean M, Friman S, ..., Herlenius G, Thorsell A

Int J Mol Sci 23 (19) - [2022-10-08; online 2022-10-08]

The dark side of foetal bovine serum in extracellular vesicle studies.

Urzì O, Bagge RO, Crescitelli R

J Extracell Vesicles 11 (10) e12271 [2022-10-00; online 2022-10-11]

Cytokine responses to LPS in reprogrammed monocytes are associated with the transcription factor PU.1.

Tuerxun K, Midtbö K, Särndahl E, ..., Eklund D, X-HiDE Consortium

J Leukoc Biol 112 (4) 679-692 [2022-10-00; online 2022-03-13]

Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1α: Interplay between O-linked glycosylation and inflammatory cytokines.

Huang S, Thomsson KA, Jin C, ..., Krawetz R, Karlsson NG

Front Mol Biosci 9 (-) 942406 [2022-09-21; online 2022-09-21]

Expansion of nickel binding- and histidine-rich proteins during gastric adaptation of Helicobacter species.

Fischer F, Vorontsov E, Turlin E, ..., Vinella D, De Reuse H

Metallomics 14 (9) - [2022-09-12; online 2022-08-25]

Sialic Acid and Fucose Residues on the SARS-CoV-2 Receptor-Binding Domain Modulate IgG Antibody Reactivity.

Samuelsson E, Mirgorodskaya E, Nyström K, ..., Liljeqvist JÅ, Nordén R

ACS Infect Dis 8 (9) 1883-1893 [2022-09-09; online 2022-08-18]

Human CD38 regulates B cell antigen receptor dynamic organization in normal and malignant B cells.

Camponeschi A, Kläsener K, Sundell T, ..., Reth M, Mårtensson IL

J. Exp. Med. 219 (9) - [2022-09-05; online 2022-07-12]

Quantitative Proteomics Identifies Proteins Enriched in Large and Small Extracellular Vesicles.

Lischnig A, Bergqvist M, Ochiya T, Lässer C

Mol. Cell Proteomics 21 (9) 100273 [2022-09-00; online 2022-07-30]

Glycosaminoglycan linkage region of urinary bikunin as a potentially useful biomarker for β3GalT6-deficient spondylodysplastic Ehlers-Danlos syndrome.

Nikpour M, Noborn F, Nilsson J, ..., Malfait F, Larson G

JIMD Rep 63 (5) 462-467 [2022-09-00; online 2022-06-28]

Increased expression and accumulation of GDF15 in IPF extracellular matrix contribute to fibrosis.

Radwanska A, Cottage CT, Piras A, ..., Hogaboam CM, Murray LA

JCI Insight 7 (16) - [2022-08-22; online 2022-08-22]

Sulfated glycan recognition by carbohydrate sulfatases of the human gut microbiota.

Luis AS, Baslé A, Byrne DP, ..., Martens EC, Cartmell A

Nat. Chem. Biol. 18 (8) 841-849 [2022-08-00; online 2022-06-16]

Site-specific glycosylation of proteoglycans: A revisited frontier in proteoglycan research.

Noborn F, Nilsson J, Larson G

Matrix Biol. 111 (-) 289-306 [2022-08-00; online 2022-07-15]

Validated Growth Rate-Dependent Regulation of Lipid Metabolism in Yarrowia lipolytica.

Poorinmohammad N, Fu J, Wabeke B, Kerkhoven EJ

Int J Mol Sci 23 (15) - [2022-07-31; online 2022-07-31]

In vivo Characterization of Endogenous Protein Interactomes in Drosophila Larval Brain, Using a CRISPR/Cas9-based Strategy and BioID-based Proximity Labeling.

Uçkun E, Wolfstetter G, Fuchs J, Palmer RH

BIO-PROTOCOL 12 (13) - [2022-07-05; online 2022-07-05]

Role of endogenous incretins in the regulation of postprandial lipoprotein metabolism

Taskinen MR, Matikainen N, Björnson E, ..., Packard CJ, Borén J

Eur. J. Endocrinol. 187 (1) 75-84 [2022-07-01; online 2022-05-19]

Suppressors of amyloid-β toxicity improve recombinant protein production in yeast by reducing oxidative stress and tuning cellular metabolism.

Chen X, Li X, Ji B, ..., Siewers V, Engqvist MKM

Metab. Eng. 72 (-) 311-324 [2022-07-00; online 2022-05-01]

Characterization of Decellularized Implants for Extracellular Matrix Integrity and Immune Response Elicitation.

Banerjee D, Nayakawde NB, Antony D, ..., Ul Haq U, Olausson M

Tissue Eng Part A 28 (13-14) 621-639 [2022-07-00; online 2022-06-21]

Glycoproteomics and MS Proteomics [Collaborative] Integrated Microscopy Technologies Gothenburg [Collaborative]

A novel non-invasive method allowing for discovery of pathologically relevant proteins from small airways.

Östling J, Van Geest M, Olsson HK, ..., Mirgorodskaya E, Olin AC

Clin Proteomics 19 (1) 20 [2022-06-06; online 2022-06-06]

Identification of Antibiotic Resistance Proteins via MiCId's Augmented Workflow. A Mass Spectrometry-Based Proteomics Approach.

Alves G, Ogurtsov A, Karlsson R, ..., Moore ERB, Yu YK

J. Am. Soc. Mass Spectrom. 33 (6) 917-931 [2022-06-01; online 2022-05-02]

Clinical Genomics Gothenburg [Collaborative] Glycoproteomics and MS Proteomics [Service]

Site-specific N-glycan profiles of α5 β1 integrin from rat liver.

Mirgorodskaya E, Dransart E, Shafaq-Zadah M, ..., Leffler H, Johannes L

Biol Cell 114 (6) 160-176 [2022-06-00; online 2022-03-31]

Dataset for suppressors of amyloid-β toxicity and their functions in recombinant protein production in yeast.

Chen X, Li X, Ji B, ..., Siewers V, Engqvist MKM

Data Brief 42 (-) 108322 [2022-06-00; online 2022-05-27]

Optimized sample preparation and data analysis for TMT proteomic analysis of cerebrospinal fluid applied to the identification of Alzheimer's disease biomarkers.

Weiner S, Sauer M, Visser PJ, ..., Zetterberg H, Gobom J

Clin Proteomics 19 (1) 13 [2022-05-14; online 2022-05-14]

The proteome signature of cord blood plasma with high hematopoietic stem and progenitor cell count

Nilsson AK, Rydbeck H, Thorsell A, ..., Lundgren P, Hellström A

Stem Cell Research 61 (-) 102752 [2022-05-00; online 2022-05-00]

Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples.

Karimi N, Dalirfardouei R, Dias T, Lötvall J, Lässer C

J Extracell Vesicles 11 (5) e12213 [2022-05-00; online 2022-05-08]

Age and sex effects across the blood proteome after ionizing radiation exposure can bias biomarker screening and risk assessment.

Langen B, Vorontsov E, Spetz J, ..., Helou K, Forssell-Aronsson E

Sci Rep 12 (1) 7000 [2022-04-29; online 2022-04-29]

Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Zalem D, Juhás M, Terrinoni M, ..., Connell TD, Teneberg S

Glycobiology 32 (5) 391-403 [2022-04-21; online 2022-01-02]

Silencing of STE20-type kinase STK25 in human aortic endothelial and smooth muscle cells is atheroprotective.

Cansby E, Kumari S, Caputo M, ..., Goncalves I, Mahlapuu M

Commun Biol 5 (1) 379 [2022-04-19; online 2022-04-19]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Glycoproteomics and MS Proteomics [Service] Systems Biology [Collaborative]

Glycoproteomic and Phenotypic Elucidation of B4GALNT2 Expression Variants in the SID Histo-Blood Group System.

Stenfelt L, Nilsson J, Hellberg Å, ..., Larson G, Olsson ML

Int J Mol Sci 23 (7) - [2022-04-01; online 2022-04-01]

Characterization of novel nonacid glycosphingolipids as biomarkers of human gastric adenocarcinoma.

Jin C, Teneberg S

J. Biol. Chem. 298 (4) 101732 [2022-04-00; online 2022-02-15]

Extracellular endosulfatase Sulf-2 harbors a chondroitin/dermatan sulfate chain that modulates its enzyme activity.

El Masri R, Seffouh A, Roelants C, ..., Filhol O, Vivès RR

Cell Rep 38 (11) 110516 [2022-03-15; online 2022-03-17]

Computational Modeling of O-Linked Glycan Biosynthesis in CHO Cells.

Kouka T, Akase S, Sogabe I, ..., Karlsson NG, Aoki-Kinoshita KF

Molecules 27 (6) - [2022-03-08; online 2022-03-08]

The Role of Antibiotic Resistance Genes in the Fitness Cost of Multiresistance Plasmids.

Rajer F, Sandegren L

MBio 13 (1) e0355221 [2022-02-22; online 2022-01-18]

Larsson M, Rudqvist NP, Spetz J, ..., Helou K, Forssell-Aronsson E

Sci Rep 12 (1) 2107 [2022-02-08; online 2022-02-08]

Proteomic characterisation of polyglucosan bodies in skeletal muscle in RBCK1 deficiency.

Thomsen C, Malfatti E, Jovanovic A, ..., Lindberg C, Oldfors A

Neuropathol Appl Neurobiol 48 (1) e12761 [2022-02-00; online 2021-09-12]

Clinical Genomics Gothenburg [Service] Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Overexpression of the SARS-CoV-2 receptor angiotensin converting enzyme 2 in cardiomyocytes of failing hearts.

Vukusic K, Thorsell A, Muslimovic A, ..., Sandstedt J, Hammarsten O

Sci Rep 12 (1) 965 [2022-01-19; online 2022-01-19]

Year 2021

Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast.

Malina C, Yu R, Björkeroth J, Kerkhoven EJ, Nielsen J

Proc. Natl. Acad. Sci. U.S.A. 118 (51) - [2021-12-21; online 2021-12-15]

Changes in the Proteome in the Development of Chronic Human Papillomavirus Infection-A Prospective Study in HIV Positive and HIV Negative Rwandan Women.

Bienvenu E, Mukanyangezi MF, Rulisa S, ..., Tobin G, Giglio D

Cancers (Basel) 13 (23) - [2021-11-28; online 2021-11-28]

ATR inhibition enables complete tumour regression in ALK-driven NB mouse models.

Szydzik J, Lind DE, Arefin B, ..., Hallberg B, Palmer RH

Nat Commun 12 (1) 6813 [2021-11-24; online 2021-11-24]

In vivo Profiling of the Alk Proximitome in the Developing Drosophila Brain.

Uçkun E, Wolfstetter G, Anthonydhason V, ..., Fuchs J, Palmer RH

J. Mol. Biol. 433 (23) 167282 [2021-11-19; online 2021-10-06]

Platelet proteome and function in X-linked thrombocytopenia with thalassemia and in silico comparisons with gray platelet syndrome.

Bergemalm D, Ramström S, Kardeby C, ..., Palmblad J, Åström M

Haematologica 106 (11) 2947-2959 [2021-11-01; online 2021-11-01]

Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis.

Kawahara R, Chernykh A, Alagesan K, ..., Packer NH, Thaysen-Andersen M

Nat. Methods 18 (11) 1304-1316 [2021-11-00; online 2021-11-01]

Glycoproteomics and MS Proteomics [Technology development]

A Glycoproteomic Approach to Identify Novel Proteoglycans.

Noborn F, Nikpour M, Persson A, ..., Nilsson J, Larson G

Methods Mol. Biol. 2303 (-) 71-85 [2021-10-10; online 2021-10-10]

Glycoproteomics and MS Proteomics [Technology development]

Proteomic analysis in diffuse large B-cell lymphoma identifies dysregulated tumor microenvironment proteins in non-GCB/ABC subtype patients.

Bram Ednersson S, Stern M, Fagman H, ..., Thorsell A, Andersson PO

Leuk. Lymphoma 62 (10) 2360-2373 [2021-10-00; online 2021-06-11]

A single sulfatase is required to access colonic mucin by a gut bacterium.

Luis AS, Jin C, Pereira GV, ..., Cartmell A, Martens EC

Nature 598 (7880) 332-337 [2021-10-00; online 2021-10-06]

Sulfation of O-glycans on Mucin-type Proteins From Serous Ovarian Epithelial Tumors.

Thomsson KA, Vitiazeva V, Mateoiu C, ..., Sundfeldt K, Karlsson NG

Mol. Cell Proteomics 20 (-) 100150 [2021-09-21; online 2021-09-21]

BioID-Screening Identifies PEAK1 and SHP2 as Components of the ALK Proximitome in Neuroblastoma Cells.

Uçkun E, Siaw JT, Guan J, ..., Hallberg B, Palmer RH

J. Mol. Biol. 433 (19) 167158 [2021-09-17; online 2021-07-15]

Proteoglycan profiling of human, rat and mouse insulin-secreting cells.

Nikpour M, Nilsson J, Persson A, ..., Vorontsov E, Larson G

Glycobiology 31 (8) 916-930 [2021-09-09; online 2021-05-18]

Expanding the Chondroitin Sulfate Glycoproteome - But How Far?

Noborn F, Nikpour M, Persson A, Nilsson J, Larson G

Front Cell Dev Biol 9 (-) 695970 [2021-08-13; online 2021-08-13]

Quantitative proteomic analysis to identify differentially expressed proteins in patients with epilepsy.

Banote RK, Larsson D, Berger E, Kumlien E, Zelano J

Epilepsy Res 174 (-) 106674 [2021-08-00; online 2021-05-15]

Mass Spectrometry Proteotyping-Based Detection and Identification of Staphylococcus aureus, Escherichia coli, and Candida albicans in Blood.

Kondori N, Kurtovic A, Piñeiro-Iglesias B, ..., Moore ERB, Karlsson R

Front. Cell. Infect. Microbiol. 11 (-) 634215 [2021-07-26; online 2021-07-26]

Clinical Genomics Gothenburg [Collaborative] Glycoproteomics and MS Proteomics [Service]

Synthetic bacterial vesicles combined with tumour extracellular vesicles as cancer immunotherapy.

Park KS, Svennerholm K, Crescitelli R, ..., Gribonika I, Lötvall J

J Extracell Vesicles 10 (9) e12120 [2021-07-00; online 2021-07-03]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

An Hsp90 co-chaperone links protein folding and degradation and is part of a conserved protein quality control.

Eisele F, Eisele-Bürger AM, Hao X, ..., Liu B, Nyström T

Cell Rep 35 (13) 109328 [2021-06-29; online 2021-07-01]

Evidence for discrete modes of YAP1 signaling via mRNA splice isoforms in development and diseases.

Vrbský J, Vinarský V, Perestrelo AR, ..., Pagliari S, Forte G

Genomics 113 (3) 1349-1365 [2021-05-00; online 2021-03-11]

Effects of liraglutide on the metabolism of triglyceride‐rich lipoproteins in type 2 diabetes

Taskinen M, Björnson E, Matikainen N, ..., Packard CJ, Borén J

Diabetes Obes Metab 23 (5) 1191-1201 [2021-05-00; online 2021-03-05]

Immune-Associated Proteins Are Enriched in Lung Tissue-Derived Extracellular Vesicles during Allergen-Induced Eosinophilic Airway Inflammation.

Lässer C, Kishino Y, Park KS, ..., Rådinger M, Lötvall J

Int J Mol Sci 22 (9) - [2021-04-29; online 2021-04-29]

Loss of RET Promotes Mesenchymal Identity in Neuroblastoma Cells.

Siaw JT, Gabre JL, Uçkun E, ..., Palmer RH, Guan J

Cancers (Basel) 13 (8) - [2021-04-15; online 2021-04-15]

CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway.

Montoliu-Gaya L, Tietze D, Kaminski D, ..., Tietze AA, Sterky FH

EMBO Rep. 22 (4) e51349 [2021-04-07; online 2021-02-15]

Glycoproteomics and MS Proteomics [Collaborative] Swedish NMR Centre (SNC) [Service]

Domain Mapping of Chondroitin/Dermatan Sulfate Glycosaminoglycans Enables Structural Characterization of Proteoglycans.

Persson A, Nikpour M, Vorontsov E, Nilsson J, Larson G

Mol. Cell Proteomics 20 (-) 100074 [2021-03-20; online 2021-03-20]

Quantifying absolute gene expression profiles reveals distinct regulation of central carbon metabolism genes in yeast.

Yu R, Vorontsov E, Sihlbom C, Nielsen J

Elife 10 (-) - [2021-03-15; online 2021-03-15]

Isolation and characterization of extracellular vesicle subpopulations from tissues.

Crescitelli R, Lässer C, Lötvall J

Nat Protoc 16 (3) 1548-1580 [2021-03-00; online 2021-01-25]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Collaborative]

Elastin-like recombinamers-based hydrogel modulates post-ischemic remodeling in a non-transmural myocardial infarction in sheep.

Contessotto P, Orbanić D, Da Costa M, ..., Rodríguez-Cabello JC, Pandit A

Sci Transl Med 13 (581) - [2021-02-17; online 2021-02-19]

ALK ligand ALKAL2 potentiates MYCN-driven neuroblastoma in the absence of ALK mutation.

Borenäs M, Umapathy G, Lai WY, ..., Hallberg B, Palmer RH

EMBO J. 40 (3) e105784 [2021-02-01; online 2021-01-07]

Clinical Genomics Gothenburg [Collaborative] Glycoproteomics and MS Proteomics [Service]

Elastin-like hydrogel stimulates angiogenesis in a severe model of critical limb ischemia (CLI): An insight into the glyco-host response.

Marsico G, Jin C, Abbah SA, ..., McCullagh KJA, Pandit A

Biomaterials 269 (-) 120641 [2021-02-00; online 2021-01-04]

Effects of Evolocumab on the Postprandial Kinetics of Apo (Apolipoprotein) B100- and B48-Containing Lipoproteins in Subjects With Type 2 Diabetes.

Taskinen MR, Björnson E, Kahri J, ..., Packard CJ, Borén J

Arterioscler. Thromb. Vasc. Biol. 41 (2) 962-975 [2021-02-00; online 2020-12-24]

Telomeric double-strand DNA-binding proteins DTN-1 and DTN-2 ensure germline immortality in Caenorhabditis elegans.

Yamamoto I, Zhang K, Zhang J, Vorontsov E, Shibuya H

Elife 10 (-) - [2021-01-21; online 2021-01-21]

Embryo-Like Features in Developing Bacillus subtilis Biofilms.

Futo M, Opašić L, Koska S, ..., Mijakovic I, Domazet-Lošo T

Mol. Biol. Evol. 38 (1) 31-47 [2021-01-04; online 2020-09-02]

The structure of enteric human adenovirus 41-A leading cause of diarrhea in children.

Rafie K, Lenman A, Fuchs J, ..., Arnberg N, Carlson LA

Sci Adv 7 (2) - [2021-01-00; online 2021-01-08]

Cryo-EM [Service] Glycoproteomics and MS Proteomics [Collaborative]

Novel non-invasive particles in exhaled air method to explore the lining fluid of small airways-a European population-based cohort study.

Hussain-Alkhateeb L, Bake B, Holm M, ..., Mirgorodskaya E, Olin A

BMJ Open Respir Res 8 (1) - [2021-01-00; online 2021-01-07]

A novel type of colistin resistance genes selected from random sequence space.

Knopp M, Babina AM, Gudmundsdóttir JS, ..., Trent MS, Andersson DI

PLoS Genet. 17 (1) e1009227 [2021-01-00; online 2021-01-07]

Year 2020

Proteomic analysis of follicular fluid during human ovulation.

Zakerkish F, Brännström M, Carlsohn E, ..., van der Post S, Thoroddsen A

Acta Obstet Gynecol Scand 99 (7) 917-924 [2020-07-00; online 2020-04-07]

Evolution of a New Function by Fusion between Phage DNA and a Bacterial Gene.

Warsi O, Knopp M, Surkov S, Jerlström Hultqvist J, Andersson DI

Mol. Biol. Evol. 37 (5) 1329-1341 [2020-05-01; online 2020-01-25]

Discovery of Species-unique Peptide Biomarkers of Bacterial Pathogens by Tandem Mass Spectrometry-based Proteotyping.

Karlsson R, Thorsell A, Gomila M, ..., Kristiansson E, Moore ERB

Mol. Cell Proteomics 19 (3) 518-528 [2020-03-00; online 2020-01-15]

Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation.

Crescitelli R, Lässer C, Jang SC, ..., Olofsson Bagge R, Lötvall J

J Extracell Vesicles 9 (1) 1722433 [2020-02-11; online 2020-02-11]

Glycoproteomics and MS Proteomics [Collaborative] Integrated Microscopy Technologies Gothenburg [Service]

Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage.

Visuttijai K, Hedberg-Oldfors C, Thomsen C, ..., Roach P, Oldfors A

J. Clin. Endocrinol. Metab. 105 (2) 557-566 [2020-02-01; online 2019-10-20]

Exosomes influence the behavior of human mesenchymal stem cells on titanium surfaces.

Wang X, Shah FA, Vazirisani F, ..., Ekström K, Thomsen P

Biomaterials 230 (-) 119571 [2020-02-00; online 2019-10-24]

NIST Interlaboratory Study on Glycosylation Analysis of Monoclonal Antibodies: Comparison of Results from Diverse Analytical Methods.

De Leoz MLA, Duewer DL, Fung A, ..., Yuan H, Stein SE

Mol. Cell Proteomics 19 (1) 11-30 [2020-01-00; online 2019-10-07]

Molecular mechanisms of collateral sensitivity to the antibiotic nitrofurantoin.

Roemhild R, Linkevicius M, Andersson DI

PLoS Biol. 18 (1) e3000612 [2020-01-00; online 2020-01-27]

Year 2019

Structural and biochemical studies of the glucuronoyl esterase OtCE15A illuminate its interaction with lignocellulosic components.

Mazurkewich S, Poulsen JN, Lo Leggio L, Larsbrink J

J. Biol. Chem. 294 (52) 19978-19987 [2019-12-27; online 2019-11-18]

Lipid Droplet-Associated Kinase STK25 Regulates Peroxisomal Activity and Metabolic Stress Response in Steatotic Liver.

Nerstedt A, Kurhe Y, Cansby E, ..., Hoy AJ, Mahlapuu M

J. Lipid Res. - (-) - [2019-12-19; online 2019-12-19]

Apolipoprotein B48 metabolism in chylomicrons and very low-density lipoproteins and its role in triglyceride transport in normo- and hypertriglyceridemic human subjects.

Björnson E, Packard CJ, Adiels M, ..., Taskinen MR, Borén J

J. Intern. Med. - (-) - [2019-12-17; online 2019-12-17]

Mitochondrial protein enriched extracellular vesicles discovered in human melanoma tissues can be detected in patient plasma

Jang SC, Crescitelli R, Cvjetkovic A, ..., Kalluri R, Lötvall J

J Extracell Vesicles 8 (1) 1635420 [2019-12-01; online 2019-08-27]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Endosomal signalling via exosome surface TGFβ-1

Shelke GV, Yin Y, Jang SC, ..., Nilsson JA, Lötvall J

J Extracell Vesicles 8 (1) 1650458 [2019-12-01; online 2019-09-20]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service] Integrated Microscopy Technologies Stockholm

Towards a standardized bioinformatics infrastructure for N- and O-glycomics

Rojas-Macias MA, Mariethoz J, Andersson P, ..., Lisacek F, Karlsson NG

Nat Commun 10 (1) - [2019-12-00; online 2019-07-22]

Bioinformatics Support and Infrastructure [Technology development] Bioinformatics Support, Infrastructure and Training [Technology development] Glycoproteomics and MS Proteomics [Technology development]

Protein Paucimannosylation Is an Enriched N-Glycosylation Signature of Human Cancers.

Chatterjee S, Lee LY, Kawahara R, ..., Palmisano G, Thaysen-Andersen M

Proteomics 19 (21-22) e1900010 [2019-11-00; online 2019-10-16]

Mice exposed to maternal androgen excess and diet-induced obesity have altered phosphorylation of catechol-O-methyltransferase in the placenta and fetal liver.

Fornes R, Manti M, Qi X, ..., Benrick A, Stener-Victorin E

Int J Obes (Lond) 43 (11) 2176-2188 [2019-11-00; online 2019-01-22]

DPI Selectively Inhibits Intracellular NADPH Oxidase Activity in Human Neutrophils.

Buck A, Sanchez Klose FP, Venkatakrishnan V, ..., Christenson K, Bylund J

Immunohorizons 3 (10) 488-497 [2019-10-18; online 2019-10-18]

Reduced sialyl-Lewisx on salivary MUC7 from patients with burning mouth syndrome.

Acharya S, Jin C, Bylund J, ..., Carlén A, Karlsson NG

Mol Omics 15 (5) 331-339 [2019-10-07; online 2019-08-16]

Affinity Proteomics Uppsala [Collaborative] Glycoproteomics and MS Proteomics [Collaborative] PLA and Single Cell Proteomics [Collaborative]

Upregulation of PBP1B and LpoB in cysB Mutants Confers Mecillinam (Amdinocillin) Resistance in Escherichia coli.

Thulin E, Andersson DI

Antimicrob. Agents Chemother. 63 (10) - [2019-10-00; online 2019-09-23]

Discovery and development of substituted thiadiazoles as inhibitors of Staphylococcus aureus Sortase A

Wehrli PM, Uzelac I, Olsson T, ..., Tietze D, Gottfries J

Bioorganic & Medicinal Chemistry 27 (19) 115043 [2019-10-00; online 2019-10-00]

Chemical Biology Consortium Sweden (CBCS) [Service] Glycoproteomics and MS Proteomics [Service] Swedish NMR Centre (SNC) [Service]

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions.

Akula MK, Ibrahim MX, Ivarsson EG, ..., Sayin VI, Bergo MO

Nat Commun 10 (1) 3975 [2019-09-04; online 2019-09-04]

Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans.

Cansby E, Kulkarni NM, Magnusson E, ..., Blüher M, Mahlapuu M

FASEB J. 33 (9) 9974-9989 [2019-09-00; online 2019-06-07]

Separation of Isomeric O-Glycans by Ion Mobility and Liquid Chromatography-Mass Spectrometry.

Jin C, Harvey DJ, Struwe WB, Karlsson NG

Anal. Chem. 91 (16) 10604-10613 [2019-08-20; online 2019-08-01]

Glycoproteomics and MS Proteomics [Technology development]

Glycosylation influences activity, stability and immobilization of the feruloyl esterase 1a from Myceliophthora thermophila.

Bonzom C, Hüttner S, Mirgorodskaya E, ..., Verhaert RMD, Olsson L

AMB Express 9 (1) 126 [2019-08-12; online 2019-08-12]

Deciphering Isomers with a Multiple Reaction Monitoring Method for the Complete Detectable O-Glycan Repertoire of the Candidate Therapeutic, Lubricin.

Flowers SA, Lane CS, Karlsson NG

Anal. Chem. 91 (15) 9819-9827 [2019-08-06; online 2019-07-11]

Glycoproteomics and MS Proteomics [Technology development]

Role of apolipoprotein C-III overproduction in diabetic dyslipidaemia.

Adiels M, Taskinen MR, Björnson E, ..., Packard C, Borén J

Diabetes Obes Metab 21 (8) 1861-1870 [2019-08-00; online 2019-05-08]

A targeted proteomics approach reveals a serum protein signature as diagnostic biomarker for resectable gastric cancer.

Shen Q, Polom K, Williams C, ..., Roviello F, Kamali-Moghaddam M

EBioMedicine 44 (-) 322-333 [2019-06-00; online 2019-05-28]

Affinity Proteomics Uppsala [Technology development] Bioinformatics Support for Computational Resources [Service] Clinical Biomarkers [Service] Glycoproteomics and MS Proteomics [Collaborative] PLA and Single Cell Proteomics [Technology development]

Distinct glycosylation in membrane proteins within neonatal versus adult myocardial tissue.

Contessotto P, Ellis BW, Jin C, ..., Kilcoyne M, Pandit A

Matrix Biol. - (-) - [2019-05-17; online 2019-05-17]

Identification of a non-canonical chondroitin sulfate linkage region trisaccharide.

Persson A, Nilsson J, Vorontsov E, Noborn F, Larson G

Glycobiology 29 (5) 366-371 [2019-05-01; online 2019-03-03]

Investigation of human apoB48 metabolism using a new, integrated non-steady-state model of apoB48 and apoB100 kinetics.

Björnson E, Packard CJ, Adiels M, ..., Taskinen MR, Borén J

J. Intern. Med. 285 (5) 562-577 [2019-05-00; online 2019-03-12]

Helicobacter suis infection alters glycosylation and decreases the pathogen growth inhibiting effect and binding avidity of gastric mucins.

Padra M, Adamczyk B, Flahou B, ..., Karlsson NG, Lindén SK

Mucosal Immunol 12 (3) 784-794 [2019-05-00; online 2019-03-07]

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

Lindén M, Thomsen C, Grundevik P, ..., Ståhlberg A, Åman P

EMBO Rep. 20 (5) - [2019-05-00; online 2019-04-08]

Preeclampsia is Associated with Sex-Specific Transcriptional and Proteomic Changes in Fetal Erythroid Cells.

Masoumi Z, Maes GE, Herten K, ..., Familari M, Hansson SR

Int J Mol Sci 20 (8) - [2019-04-25; online 2019-04-25]

Exploring the Arctic Charr Intestinal Glycome: Evidence of Increased N-Glycolylneuraminic Acid Levels and Changed Host-Pathogen Interactions in Response to Inflammation.

Venkatakrishnan V, Padra JT, Sundh H, ..., Karlsson NG, Lindén SK

J. Proteome Res. 18 (4) 1760-1773 [2019-04-05; online 2019-03-19]

Univariate and classification analysis reveals potential diagnostic biomarkers for early stage ovarian cancer Type 1 and Type 2.

Marcišauskas S, Ulfenborg B, Kristjansdottir B, Waldemarson S, Sundfeldt K

J Proteomics 196 (-) 57-68 [2019-03-30; online 2019-01-30]

Recombinant Glycoprotein E of Varicella Zoster Virus Contains Glycan-Peptide Motifs That Modulate B Cell Epitopes into Discrete Immunological Signatures.

Nordén R, Nilsson J, Samuelsson E, ..., Olofsson S, Bergström T

Int J Mol Sci 20 (4) - [2019-02-22; online 2019-02-22]

GlyConnect: Glycoproteomics Goes Visual, Interactive, and Analytical.

Alocci D, Mariethoz J, Gastaldello A, ..., Packer NH, Lisacek F

J. Proteome Res. 18 (2) 664-677 [2019-02-01; online 2019-01-15]

The bile salt glycocholate induces global changes in gene and protein expression and activates virulence in enterotoxigenic Escherichia coli.

Joffre E, Nicklasson M, Álvarez-Carretero S, ..., Zhu B, Sjöling Å

Sci Rep 9 (1) 108 [2019-01-14; online 2019-01-14]

Year 2018

Proteotyping bacteria: Characterization, differentiation and identification of pneumococcus and other species within the Mitis Group of the genus Streptococcus by tandem mass spectrometry proteomics.

Karlsson R, Gonzales-Siles L, Gomila M, ..., Kristiansson E, Moore ERB

PLoS ONE 13 (12) e0208804 [2018-12-10; online 2018-12-10]

A novel ulvan lyase family with broad-spectrum activity from the ulvan utilisation loci of Formosa agariphila KMM 3901

Konasani VR, Jin C, Karlsson NG, Albers E

Sci Rep 8 (1) - [2018-12-00; online 2018-10-02]

Glycoproteomics and MS Proteomics [Service] Swedish NMR Centre (SNC) [Service]

Isomeric Separation and Recognition of Anionic and Zwitterionic N-glycans from Royal Jelly Glycoproteins.

Hykollari A, Malzl D, Eckmair B, ..., Wilson IBH, Paschinger K

Mol. Cell Proteomics 17 (11) 2177-2196 [2018-11-00; online 2018-08-13]

Glycomics@ExPASy: Bridging the Gap.

Mariethoz J, Alocci D, Gastaldello A, ..., Packer NH, Lisacek F

Mol. Cell Proteomics 17 (11) 2164-2176 [2018-11-00; online 2018-08-10]

Copper Chaperone Atox1 Interacts with Cell Cycle Proteins.

Matson Dzebo M, Blockhuys S, Valenzuela S, ..., Esbjörner EK, Wittung-Stafshede P

Computational and Structural Biotechnology Journal 16 (-) 443-449 [2018-10-31; online 2018-10-31]

Detection of post-translational modifications using solid-phase proximity ligation assay.

Oliveira FMS, Mereiter S, Lönn P, ..., Reis CA, Kamali-Moghaddam M

N Biotechnol 45 (-) 51-59 [2018-10-25; online 2017-10-31]

Affinity Proteomics Uppsala [Technology development] Glycoproteomics and MS Proteomics [Technology development] PLA and Single Cell Proteomics [Technology development]

Amplification of the Melanocortin-1 Receptor in Nephrotic Syndrome Identifies a Target for Podocyte Cytoskeleton Stabilization.

Bergwall L, Wallentin H, Elvin J, ..., Nyström J, Buvall L

Sci Rep 8 (1) 15731 [2018-10-24; online 2018-10-24]

Identification of Potential Plasma Biomarkers for Abdominal Aortic Aneurysm Using Tandem Mass Tag Quantitative Proteomics.

Henriksson AE, Lindqvist M, Sihlbom C, Bergström J, Bylund D

Proteomes 6 (4) - [2018-10-18; online 2018-10-18]

BabA-mediated adherence of pediatric ulcerogenic H. pylori strains to gastric mucins at neutral and acidic pH.

Quintana-Hayashi MP, Rocha R, Padra M, ..., Oleastro M, Lindén SK

Virulence 9 (1) 1699-1717 [2018-10-10; online 2018-10-10]

Higher Energy Collisional Dissociation Mass Spectrometry of Sulfated O-Linked Oligosaccharides.

Issa SMA, Vitiazeva V, Hayes CA, Karlsson NG

J. Proteome Res. 17 (9) 3259-3267 [2018-09-07; online 2018-08-13]

Glycoproteomics and MS Proteomics [Technology development]

The Thomsen-Friedenreich Antigen: A Highly Sensitive and Specific Predictor of Microsatellite Instability in Gastric Cancer.

Mereiter S, Polom K, Williams C, ..., Magalhães A, Reis CA

J Clin Med 7 (9) - [2018-09-05; online 2018-09-05]

Pharmacokinetic Properties of the Nephrotoxin Orellanine in Rats.

Najar D, Haraldsson B, Thorsell A, ..., Nyström J, Ebefors K

Toxins (Basel) 10 (8) - [2018-08-17; online 2018-08-17]

Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins

Karimi N, Cvjetkovic A, Jang SC, ..., Lötvall J, Lässer C

Cell. Mol. Life Sci. 75 (15) 2873-2886 [2018-08-00; online 2018-02-13]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

A bacteriophage enzyme induces bacterial metabolic perturbation that confers a novel promiscuous function.

Jerlström Hultqvist J, Warsi O, Söderholm A, ..., Selmer M, Andersson DI

Nat Ecol Evol 2 (8) 1321-1330 [2018-08-00; online 2018-05-28]

Effective Assignment of α2,3/α2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics.

Pett C, Nasir W, Sihlbom C, ..., Nilsson J, Westerlind U

Angew. Chem. Int. Ed. Engl. 57 (30) 9320-9324 [2018-07-20; online 2018-06-20]

Glycoproteomics and MS Proteomics [Technology development]

LC-MS/MS characterization of xyloside-primed glycosaminoglycans with cytotoxic properties reveals structural diversity and novel glycan modifications.

Persson A, Gomez Toledo A, Vorontsov E, ..., Nilsson J, Larson G

J. Biol. Chem. 293 (26) 10202-10219 [2018-06-29; online 2018-05-08]

Expression of ribosomal and actin network proteins and immunochemotherapy resistance in diffuse large B cell lymphoma patients

Bram Ednersson S, Stenson M, Stern M, ..., Hasselblom S, Andersson PO

Br J Haematol 181 (6) 770-781 [2018-06-00; online 2018-05-16]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Cracking the Sugar Code by Mass Spectrometry : An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award.

Mirgorodskaya E, Karlsson NG, Sihlbom C, Larson G, Nilsson CL

J. Am. Soc. Mass Spectrom. 29 (6) 1065-1074 [2018-06-00; online 2018-04-11]

Identification of Potential MR-Derived Biomarkers for Tumor Tissue Response to 177Lu-Octreotate Therapy in an Animal Model of Small Intestine Neuroendocrine Tumor.

Montelius M, Spetz J, Jalnefjord O, ..., Ljungberg M, Forssell-Aronsson E

Transl Oncol 11 (2) 193-204 [2018-04-00; online 2018-01-11]

Innate immune alterations are elicited in microglial cells before plaque deposition in the Alzheimer's disease mouse model 5xFAD.

Boza-Serrano A, Yang Y, Paulus A, Deierborg T

Sci Rep 8 (1) 1550 [2018-01-24; online 2018-01-24]

The Global Acetylome of the Human Pathogen Vibrio cholerae V52 Reveals Lysine Acetylation of Major Transcriptional Regulators.

Jers C, Ravikumar V, Lezyk M, ..., Wai SN, Mijakovic I

Front. Cell. Infect. Microbiol. 7 (-) 537 [2018-01-11; online 2018-01-11]

Sample handling of gastric tissue and O-glycan alterations in paired gastric cancer and non-tumorigenic tissues.

Adamczyk B, Jin C, Polom K, ..., Roviello F, Karlsson NG

Sci Rep 8 (1) 242 [2018-01-10; online 2018-01-10]

Glycoproteomics and MS Proteomics [Technology development]

Year 2017

Low Concentrations of Vitamin C Reduce the Synthesis of Extracellular Polymers and Destabilize Bacterial Biofilms.

Pandit S, Ravikumar V, Abdel-Haleem AM, ..., Westerlund F, Mijakovic I

Front Microbiol 8 (-) 2599 [2017-12-22; online 2017-12-22]

Orellanine specifically targets renal clear cell carcinoma.

Buvall L, Hedman H, Khramova A, ..., Haraldsson B, Nyström J

Oncotarget 8 (53) 91085-91098 [2017-10-31; online 2017-07-25]

Glycoproteomics and MS Proteomics [Technology development]

Glycoforest 1.0.

Horlacher O, Jin C, Alocci D, ..., Karlsson NG, Lisacek F

Anal. Chem. 89 (20) 10932-10940 [2017-10-17; online 2017-09-25]

Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface.

Flowers SA, Zieba A, Örnros J, ..., Kamali-Moghaddam M, Karlsson NG

Sci Rep 7 (1) 13149 [2017-10-13; online 2017-10-13]

Affinity Proteomics Uppsala [Collaborative] Glycoproteomics and MS Proteomics [Collaborative] PLA and Single Cell Proteomics [Collaborative]

Identification and characterization of the novel colonization factor CS30 based on whole genome sequencing in enterotoxigenic Escherichia coli (ETEC).

von Mentzer A, Tobias J, Wiklund G, ..., Sjöling Å, Svennerholm AM

Sci Rep 7 (1) 12514 [2017-10-02; online 2017-10-02]

GlyTouCan: an accessible glycan structure repository.

Tiemeyer M, Aoki K, Paulson J, ..., Narimatsu H, Aoki-Kinoshita KF

Glycobiology 27 (10) 915-919 [2017-10-01; online 2017-09-20]

Transcriptomic and Proteomic Profiling Provides Insight into Mesangial Cell Function in IgA Nephropathy.

Liu P, Lassén E, Nair V, ..., Ebefors K, Nyström J

J. Am. Soc. Nephrol. 28 (10) 2961-2972 [2017-10-00; online 2017-06-23]

Cartilage oligomeric matrix protein neoepitope in the synovial fluid of horses with acute lameness: A new biomarker for the early stages of osteoarthritis.

Skiöldebrand E, Ekman S, Mattsson Hultén L, ..., Sihlbom C, Rüetschi U

Equine Vet. J. 49 (5) 662-667 [2017-09-00; online 2017-02-28]

Cartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions.

Flowers SA, Kalamajski S, Ali L, ..., Karlsson NG, Jin C

Osteoarthr. Cartil. 25 (9) 1496-1504 [2017-09-00; online 2017-04-01]

Aeromonas salmonicida Growth in Response to Atlantic Salmon Mucins Differs between Epithelial Sites, Is Governed by Sialylated and N-Acetylhexosamine-Containing O-Glycans, and Is Affected by Ca2.

Padra JT, Sundh H, Sundell K, ..., Karlsson NG, Lindén SK

Infect. Immun. 85 (8) - [2017-08-00; online 2017-07-19]

Dual action of bacteriocin PLNC8 αβ through inhibition of Porphyromonas gingivalis infection and promotion of cell proliferation.

Bengtsson T, Zhang B, Selegård R, ..., Aili D, Khalaf H

Pathog Dis 75 (5) - [2017-07-31; online 2017-06-13]

D-methionine interferes with non-typeable Haemophilus influenzae peptidoglycan synthesis during growth and biofilm formation.

Dawe H, Berger E, Sihlbom C, ..., Faust SN, Allan RN

Microbiology (Reading, Engl.) 163 (7) 1093-1104 [2017-07-00; online 2017-07-21]

Typing and Characterization of Bacteria Using Bottom-up Tandem Mass Spectrometry Proteomics.

Boulund F, Karlsson R, Gonzales-Siles L, ..., Moore ERB, Kristiansson E

Mol. Cell Proteomics 16 (6) 1052-1063 [2017-06-00; online 2017-04-18]

Influence of Glycosylation on Interfacial Properties of Recombinant Mucins: Adsorption, Surface Forces, and Friction.

An J, Jin C, Dėdinaitė A, ..., Karlsson NG, Claesson PM

Langmuir 33 (18) 4386-4395 [2017-05-09; online 2017-04-26]

Structural Diversity of Human Gastric Mucin Glycans.

Jin C, Kenny DT, Skoog EC, ..., Lindén SK, Karlsson NG

Mol. Cell Proteomics 16 (5) 743-758 [2017-05-00; online 2017-05-04]

Affinity Proteomics Uppsala [Service] Glycoproteomics and MS Proteomics [Service] PLA and Single Cell Proteomics [Service]

High levels of the AR-V7 Splice Variant and Co-Amplification of the Golgi Protein Coding YIPF6 in AR Amplified Prostate Cancer Bone Metastases.

Djusberg E, Jernberg E, Thysell E, ..., Brattsand M, Wikström P

Prostate 77 (6) 625-638 [2017-05-00; online 2017-02-01]

Conversion of Glycerol to 3-Hydroxypropanoic Acid by Genetically Engineered Bacillus subtilis.

Kalantari A, Chen T, Ji B, ..., Goelzer A, Mijakovic I

Front Microbiol 8 (-) 638 [2017-04-18; online 2017-04-18]

The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.

Liu Y, McBride R, Stoll M, ..., Feizi T, Smith DF

Glycobiology 27 (4) 280-284 [2017-04-00; online 2016-11-22]

Strain improvement of Pichia kudriavzevii TY13 for raised phytase production and reduced phosphate repression.

Qvirist L, Vorontsov E, Veide Vilg J, Andlid T

Microb Biotechnol 10 (2) 341-353 [2017-03-00; online 2016-10-28]

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.

Chursa U, Nuñez-Durán E, Cansby E, ..., Sihlbom C, Mahlapuu M

Diabetologia 60 (3) 553-567 [2017-03-00; online 2016-12-16]

Anaesthetic-induced cardioprotection in an experimental model of the Takotsubo syndrome - isoflurane vs. propofol.

Oras J, Redfors B, Ali A, ..., Omerovic E, Ricksten SE

Acta Anaesthesiol Scand 61 (3) 309-321 [2017-03-00; online 2017-01-22]

Characterization of Glycan Structures of Chondroitin Sulfate-Glycopeptides Facilitated by Sodium Ion-Pairing and Positive Mode LC-MS/MS.

Nilsson J, Noborn F, Gomez Toledo A, ..., Sihlbom C, Larson G

J. Am. Soc. Mass Spectrom. 28 (2) 229-241 [2017-02-00; online 2016-11-21]

Glycoproteomics and MS Proteomics [Technology development]

Proteomic analysis of enterotoxigenic Escherichia coli (ETEC) in neutral and alkaline conditions.

Gonzales-Siles L, Karlsson R, Kenny D, Karlsson A, Sjöling Å

BMC Microbiol. 17 (1) 11 [2017-01-07; online 2017-01-07]

Proteomic analyses of limbic regions in neonatal male, female and androgen receptor knockout mice.

Zettergren A, Karlsson S, Studer E, ..., Sihlbom C, Westberg L

BMC Neurosci 18 (1) 9 [2017-01-05; online 2017-01-05]

Year 2016

High-Throughput Analysis of the Plasma N-Glycome by UHPLC.

Adamczyk B, Stöckmann H, O'Flaherty R, Karlsson NG, Rudd PM

Methods Mol. Biol. 1503 (-) 97-108 [2016-10-16; online 2016-10-16]

Glycoproteomics and MS Proteomics [Technology development]

Databases and Associated Tools for Glycomics and Glycoproteomics.

Lisacek F, Mariethoz J, Alocci D, ..., Jin C, Karlsson NG

Methods Mol. Biol. 1503 (-) 235-264 [2016-10-16; online 2016-10-16]

Year 2000

So what's a little free fluid?

Marx JA

Acad Emerg Med 7 (4) 383-384 [2000-04-00; online 2000-05-11]

Kinetics of c-phycocyanin reaction with hypochlorite.

Romay C, Gonzalez R, Pizarro M, Lissi E

J Protein Chem 19 (2) 151-155 [2000-02-00; online 2000-08-17]

Year 1977

Relationship between antibiotic feeding in animals and emergence of bacterial resistance in man.

Pohl P

J. Antimicrob. Chemother. 3 Suppl C (-) 67-72 [1977-11-00; online 1977-11-01]

The oxylog [proceedings].

PubMed

Humphrey SJ, Wolff HS

J Physiol 267 (1) 12P [1977-05-00; online 1977-05-01]