Publications 2024

Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM.

Valerie NCK, Sanjiv K, Mortusewicz O, ..., Page BDG, Altun M

Nat Commun 15 (1) 10347 [2024-12-06; online 2024-12-06]

Chemical Biology Consortium Sweden (CBCS) [Service]

Chemical exposomics in biobanked plasma samples and associations with breast cancer risk factors.

Edlund J, Sdougkou K, Papazian S, ..., Martin JW, Harlid S

J Expo Sci Environ Epidemiol - (-) - [2024-12-06; online 2024-12-06]

A landscape of X-inactivation during human T cell development.

Gylemo B, Bensberg M, Hennings V, ..., Ekwall O, Nestor CE

Nat Commun 15 (1) 10527 [2024-12-04; online 2024-12-04]

The evolutionary history of metastatic pancreatic neuroendocrine tumours reveals a therapy driven route to high-grade transformation.

Backman S, Botling J, Nord H, ..., Åkerström T, Crona J

J. Pathol. 264 (4) 357-370 [2024-12-00; online 2024-10-03]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Uppsala [Collaborative] NGI SNP genotyping [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Scifer: An R/Bioconductor package for large-scale integration of Sanger sequencing and flow cytometry data of index-sorted single cells

Arcoverde Cerveira R, Lenart K, Martin M, ..., Ols S, Loré K

Immunoinformatics (Amst) 16 (-) 100046 [2024-12-00; online 2024-12-00]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative]

Occurrence of cancer in Marfan syndrome: Report of two patients with neuroblastoma and review of the literature.

Maya-González C, Delgado-Vega AM, Taylan F, ..., Martinsson T, Nordgren A

Am. J. Med. Genet. A 194 (12) e63812 [2024-12-00; online 2024-07-11]

Longitudinal Analysis of Natural History Progression of Rare and Ultra-Rare Cerebellar Ataxias Using Item Response Theory.

Hamdan A, Hendrickx N, Hooker AC, ..., Synofzik M, Karlsson MO

Clin. Pharmacol. Ther. 116 (6) 1593-1605 [2024-12-00; online 2024-10-15]

Bioinformatics Support for Computational Resources [Service]

Lifestyle, biological, and genetic factors related to brain iron accumulation across adulthood.

Gustavsson J, Ištvánfyová Z, Papenberg G, ..., Mangialasche F, Kalpouzos G

Neurobiol. Aging 144 (-) 56-67 [2024-12-00; online 2024-09-10]

NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Genomics of severe and treatment-resistant obsessive-compulsive disorder treated with deep brain stimulation: A preliminary investigation.

Chen LL, Naesström M, Halvorsen M, ..., Crowley JJ, Pascal D

Am. J. Med. Genet. B Neuropsychiatr. Genet. 195 (8) e32983 [2024-12-00; online 2024-04-22]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Genomic signals of adaptation to a natural CO2 gradient over a striking microgeographic scale

González-Delgado S, Pérez-Portela R, Ortega-Martínez O, ..., Pereyra RT, Hernández JC

Marine Pollution Bulletin 209 (-) 117225 [2024-12-00; online 2024-12-00]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Genetic diversity insights from population genomics and machine learning tools for Nordic Arctic charr (Salvelinus alpinus) populations

Palaiokostas C, Kurta K, Pappas F, ..., Janhunen M, Kause A

Aquaculture Reports 39 (-) 102495 [2024-12-00; online 2024-12-00]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Genetic analysis and family screening for dilated cardiomyopathy: a retrospective analysis of the stepwise pedigree approach.

Ylipää J, Andersson T

Scand Cardiovasc J 58 (1) 2379356 [2024-12-00; online 2024-07-24]

Clinical Genomics Umeå [Service]

Achieving optically selective coatings of silica fixated carbon nanotubes for solar energy applications

Zäll E, Segervald J, Mahmoodi H, ..., Edman L, Wågberg T

Solar Energy Materials and Solar Cells 278 (-) 113202 [2024-12-00; online 2024-12-00]

Toward target 2035: EUbOPEN - a public-private partnership to enable & unlock biology in the open.

Tredup C, Ackloo S, Beck H, ..., Arrowsmith CH, Knapp S

RSC Med Chem - (-) - [2024-11-29; online 2024-11-29]

Chemical Biology Consortium Sweden (CBCS) [Technology development]

Spatial profiling of the mouse colonic immune landscape associated with colitis and sex.

Holm M, Stepanauskaitė L, Bäckström A, ..., Stadler C, Williams C

Commun Biol 7 (1) 1595 [2024-11-29; online 2024-11-29]

Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism.

Li P, Liu S, Wallerstein J, ..., Liin SI, Gourdon P

Nat. Struct. Mol. Biol. - (-) - [2024-11-28; online 2024-11-28]

Preanalytical (Mis)Handling of Plasma Investigated by 1H NMR Metabolomics

Malmodin D, Bay Nord A, Zafar H, ..., Karlsson BG, Naluai ÅT

ACS Omega - (-) - [2024-11-27; online 2024-11-27]

Streptolysin O accelerates the conversion of plasminogen to plasmin

Tang D, Khakzad H, Hjortswang E, ..., Happonen L, Malmström J

Nat Commun 15 (1) 10212 [2024-11-25; online 2024-11-25]

Structural Proteomics [Technology development]

Candidate serum protein biomarkers for active pulmonary tuberculosis diagnosis in tuberculosis endemic settings.

Ayalew S, Wegayehu T, Wondale B, ..., Fredolini C, Mihret A

BMC Infect. Dis. 24 (1) 1329 [2024-11-21; online 2024-11-21]

Affinity Proteomics Stockholm [Collaborative]

Visualization and analysis of medically relevant tandem repeats in nanopore sequencing of control cohorts with pathSTR.

De Coster W, Höijer I, Bruggeman I, ..., Ameur A, Rademakers R

Genome Res. 34 (11) 2074-2080 [2024-11-20; online 2024-11-20]

Clinical Genomics Uppsala [Technology development] NGI Long read [Technology development] NGI Uppsala (Uppsala Genome Center) [Technology development] National Genomics Infrastructure [Technology development]

SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF Resulting in Drastic Soluble Protein Depletion.

Christ W, Kapell S, Sobkowiak MJ, ..., El Andaloussi S, Ezzat K

ACS Chem Neurosci 15 (22) 4095-4104 [2024-11-20; online 2024-11-07]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Global Proteomics and Proteogenomics [Service]

Resolving complex duplication variants in autism spectrum disorder using long-read genome sequencing.

Eisfeldt J, Higginbotham EJ, Lenner F, ..., Scherer SW, Feuk L

Genome Res. 34 (11) 1763-1773 [2024-11-20; online 2024-11-20]

Bioinformatics Support for Computational Resources [Service] NGI Long read [Collaborative] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

One-Pot Time-Induced Proteome Integral Solubility Alteration Assay for Automated and Sensitive Drug-Target Identification.

Meng Z, Saei AA, Lyu H, Gaetani M, Zubarev RA

Anal. Chem. - (-) - [2024-11-20; online 2024-11-20]

Chemical Proteomics [Technology development]

Leveraging the T2T assembly to resolve rare and pathogenic inversions in reference genome gaps.

Bilgrav Saether K, Eisfeldt J, Bengtsson JD, ..., Carvalho CMB, Lindstrand A

Genome Res. 34 (11) 1785-1797 [2024-11-20; online 2024-11-20]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Stockholm [Service] NGI Long read [Collaborative] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

A national long-read sequencing study on chromosomal rearrangements uncovers hidden complexities.

Eisfeldt J, Ameur A, Lenner F, ..., Feuk L, Lindstrand A

Genome Res. 34 (11) 1774-1784 [2024-11-20; online 2024-11-20]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Umeå [Collaborative] Clinical Genomics Uppsala [Collaborative] NGI Long read [Technology development] NGI Uppsala (Uppsala Genome Center) [Technology development] National Genomics Infrastructure [Technology development]

Unraveling the dynamics of lignin chemistry on decomposition to understand its contribution to soil organic matter accumulation

Thirunavukkarasu A, Hedenström M, Sparrman T, ..., Schleucher J, Öquist M

Plant Soil - (-) - [2024-11-19; online 2024-11-19]

Inhibition mechanism of potential antituberculosis compound lansoprazole sulfide.

Kovalova T, Król S, Gamiz-Hernandez AP, ..., Brzezinski P, Högbom M

Proc. Natl. Acad. Sci. U.S.A. 121 (47) e2412780121 [2024-11-19; online 2024-11-12]

Detecting transposable elements in long read genomes using sTELLeR.

Bilgrav Saether K, Eisfeldt J

Bioinformatics - (-) - [2024-11-18; online 2024-11-18]

Combining live cell fluorescence imaging within situcryo electron tomography sheds light on the septation process inDeinococcus radiodurans

Gaifas L, Kleman JP, Lacroix F, ..., Gutsche I, Timmins J

- - (-) - [2024-11-18; online 2024-11-18]

Cryo-EM [Collaborative] Integrated Microscopy Technologies Umeå [Service]

Autoantibodies against a subunit of mitochondrial respiratory chain complex I in inclusion body myositis.

Notarnicola A, Hellstrom C, Horuluoglu B, ..., Nilsson P, Lundberg IE

J. Autoimmun. 149 (-) 103332 [2024-11-18; online 2024-11-18]

Autoimmunity and Serology Profiling [Collaborative]

Whole-Genome Sequencing of Invasive Neonatal Escherichia coli From Uppsala County, Sweden.

Heydecke A, Myrelid Å, Normann E, ..., Tano E, Sütterlin S

J. Infect. Dis. 230 (5) e1136-e1145 [2024-11-15; online 2024-06-13]

Bioinformatics Support for Computational Resources [Service]

Tau processing and tau-mediated inflammation differ in human APOEε2 and APOEε4 astrocytes.

Mothes T, Konstantinidis E, Eltom K, ..., Rostami J, Erlandsson A

iScience 27 (11) 111163 [2024-11-15; online 2024-10-11]

Sirtuin inhibitors reduce intracellular growth of M. tuberculosis in human macrophages via modulation of host cell immunity.

Kalsum S, Akber M, Loreti MG, ..., Lerm M, Brighenti S

Sci Rep 14 (1) 28150 [2024-11-15; online 2024-11-15]

Chemical Biology Consortium Sweden (CBCS) [Service]

Järn och gravar i Våmb

Gustafsson J, Nordman A, Hjärthner-Holdar E, Stilborg O

Jönköping läns museum arkeologisk rapport 2024:07 - (-) - [2024-11-15]

Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors.

Benediktsdottir A, Sooriyaarachchi S, Cao S, ..., Sandström A, Karlén A

Eur J Med Chem 278 (-) 116790 [2024-11-15; online 2024-08-22]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

A genome-wide association study in Swedish colorectal cancer patients with gastric- and prostate cancer in relatives.

Samola Winnberg J, Vermani L, Liu W, ..., Lindblad M, Lindblom A

Hered Cancer Clin Pract 22 (1) 25 [2024-11-14; online 2024-11-14]

Bioinformatics Support for Computational Resources [Service] NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

A comprehensive human embryo reference tool using single-cell RNA-sequencing data

Zhao C, Plaza Reyes A, Schell JP, ..., Petropoulos S, Lanner F

Nat Methods - (-) - [2024-11-14; online 2024-11-14]

Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative]

Prospective Screening of Cancer Syndromes in Patients with Mesenchymal Tumors.

Öfverholm I, Lin Y, Mondini J, ..., Haglund de Flon F, Wallander K

Cancers (Basel) 16 (22) 3816 [2024-11-13; online 2024-11-13]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Genomics Stockholm [Service]

ATP1A3 dysfunction causes motor hyperexcitability and afterhyperpolarization loss in a dystonia model.

Akkuratov EE, Sorrell F, Picton L, ..., Miles GB, Aperia A

Brain - (-) - [2024-11-13; online 2024-11-13]

Integrated Microscopy Technologies Stockholm [Service]

Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters.

García Casas P, Rossini M, Påvénius L, ..., Pizzo P, Filadi R

Nat Commun 15 (1) 9775 [2024-11-12; online 2024-11-12]

Integrated Microscopy Technologies Stockholm [Collaborative]

MassiveFold: unveiling AlphaFold's hidden potential with optimized and parallelized massive sampling.

Raouraoua N, Mirabello C, Véry T, ..., Lensink MF, Brysbaert G

Nat Comput Sci - (-) - [2024-11-11; online 2024-11-11]

Bioinformatics Support, Infrastructure and Training [Technology development]

Equid-human interactions in Medieval Rome: exploring the role and management of equids through an interdisciplinary approach

Claudia Minniti CCAMaDC

30th conference of the European Association of Archaeologists, session 3893 - (-) - [2024-11-11; online 2024-08-27]

A unique symbiosome in an anaerobic single-celled eukaryote.

Jerlström-Hultqvist J, Gallot-Lavallée L, Salas-Leiva DE, ..., Archibald JM, Roger AJ

Nat Commun 15 (1) 9726 [2024-11-09; online 2024-11-09]

Structural Variants in COL1A1 and COL1A2 in Osteogenesis Imperfecta.

Batkovskyte D, Swolin-Eide D, Hammarsjö A, ..., Åström E, Grigelioniene G

Am. J. Med. Genet. A - (-) e63935 [2024-11-08; online 2024-11-08]

Impact of thermal seed treatment on spermosphere microbiome, metabolome and viability of winter wheat.

Karlsson ME, Forsberg G, Rosberg AK, Thaning C, Alsanius B

Sci Rep 14 (1) 27197 [2024-11-08; online 2024-11-08]

Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy.

Forsthuber A, Aschenbrenner B, Korosec A, ..., Kasper M, Lichtenberger BM

Nat Commun 15 (1) 9678 [2024-11-08; online 2024-11-08]

Bioinformatics Support for Computational Resources [Service]

Cryo-EM structures of a bathy phytochrome histidine kinase reveal a unique light-dependent activation mechanism.

Bódizs S, Mészáros P, Grunewald L, Takala H, Westenhoff S

Structure 32 (11) 1952-1962.e3 [2024-11-07; online 2024-08-30]

Transmembrane peptide-loaded ionic liquid nanocarriers for targeting ErbB2-positive cancer

Abujubara H, Bharmoria P, Alvarez S, ..., Sayin V, Tietze A

- - (-) - [2024-11-06; online 2024-11-06]

Integrated Microscopy Technologies Gothenburg [Service]

The structure and function of P5A-ATPases.

Li P, Bågenholm V, Hägglund P, ..., Wang K, Gourdon P

Nat Commun 15 (1) 9605 [2024-11-06; online 2024-11-06]

Postprandial Effects of Four Test Meals Containing Wholegrain Rye or Refined Wheat Foods on Circulating Incretins, Ghrelin, Glucose, and Inflammatory Markers.

Åberg S, Webb DL, Nordin E, Hellström PM, Landberg R

J. Nutr. - (-) - [2024-11-06; online 2024-11-06]

DMI fungicide resistance in Zymoseptoria tritici is unlinked to geographical origin and genetic background: a case study in Europe.

Oreiro EG, Samils B, Kildea S, ..., Zhan J, Andersson B

Pest Manag Sci - (-) - [2024-11-06; online 2024-11-06]

NGI Long read [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Three-dimensional localization and tracking of chromosomal loci throughout the Escherichia coli cell cycle.

Karempudi P, Gras K, Amselem E, ..., Schirman D, Elf J

Commun Biol 7 (1) 1443 [2024-11-05; online 2024-11-05]

Bioinformatics Support for Computational Resources [Service]

Pasteurella multocida from deep nasal swabs and tracheobronchial lavage in bovine calves from Sweden.

Myrenås M, Pringle M, Harbom B, Bengtsson B

Acta Vet. Scand. 66 (1) 58 [2024-11-05; online 2024-11-05]

A bispecific CD40 agonistic antibody allowing for antibody-peptide conjugate formation to enable cancer-specific peptide delivery, resulting in improved T proliferation and anti-tumor immunity in mice.

Mebrahtu A, Laurén I, Veerman R, ..., Rockberg J, Mangsbo S

Nat Commun 15 (1) 9542 [2024-11-05; online 2024-11-05]

Affinity Proteomics Uppsala [Service] Drug Discovery and Development (DDD) [Service]

Urban Pigeons as Reservoirs of Critical Pathogens: Improved protocol for sequencing pigeon faeces in disease monitoring

Hermann E, Van Damme R, Bongcam-Rudloff E, Nasirzadeh L

EMBnet j. 30 (-) e1059 [2024-11-04; online 2024-11-04]

Bioinformatics Support for Computational Resources [Service] NGI Long read [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Population pharmacokinetic modelling of cetirizine concentrations in human breast milk-A contribution from the ConcePTION project.

Melander E, Nielsen EI, Lindqvist A, ..., Spigset O, Nordeng H

Basic Clin Pharmacol Toxicol - (-) - [2024-11-04; online 2024-11-04]

Drug Discovery and Development (DDD) [Collaborative]

Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases.

Rosain J, Le Voyer T, Liu X, ..., Anderson MS, Casanova JL

J. Exp. Med. 221 (11) - [2024-11-04; online 2024-10-01]

Characterisation of IBD heterogeneity using serum proteomics: A multicentre study.

Salomon B, Sudhakar P, Bergemalm D, ..., Vermeire S, Halfvarson J

J Crohns Colitis - (-) - [2024-11-04; online 2024-11-04]

Revised diffusion law permits quantitative nanoscale characterization of membrane organization

Svobodová B, Šťastný D, Blom H, ..., Hof M, Šachl R

- - (-) - [2024-11-03; online 2024-11-03]

Integrated Microscopy Technologies Stockholm [Service]

Spatial Multiomics Reveals Intratumoral Immune Heterogeneity with Distinct Cytokine Networks in Lung Cancer Brain Metastases.

Christensson G, Bocci M, Kazi JU, ..., Gonzalez Velozo H, Hagerling C

Cancer Res Commun 4 (11) 2888-2902 [2024-11-01; online 2024-10-14]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service] Clinical Genomics Lund [Service]

Perfluorooctanesulfonic acid (PFOS) induced cancer related DNA methylation alterations in human breast cells: A whole genome methylome study.

Pierozan P, Höglund A, Theodoropoulou E, Karlsson O

Sci. Total Environ. 949 (-) 174864 [2024-11-01; online 2024-07-20]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features.

Mitra S, Farswan A, Piccinelli P, ..., Pillay N, Mertens F

J. Pathol. 264 (3) 293-304 [2024-11-00; online 2024-09-11]

The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia.

Hägerstrand D, Oder B, Cortese D, ..., Sutton LA, Rosenquist R

Leukemia 38 (11) 2429-2442 [2024-11-00; online 2024-09-11]

Bioinformatics Support for Computational Resources [Service] Global Proteomics and Proteogenomics [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

The TβRI promotes migration and metastasis through thrombospondin 1 and ITGAV in prostate cancer cells.

Mu Y, Wallenius A, Zang G, ..., Mateus A, Landström M

Oncogene 43 (45) 3321-3334 [2024-11-00; online 2024-09-20]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support, Infrastructure and Training [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

The Arabidopsis splicing factor PORCUPINE/SmE1 orchestrates temperature-dependent root development via auxin homeostasis maintenance.

El Arbi N, Nardeli SM, Šimura J, Ljung K, Schmid M

New Phytol. 244 (4) 1408-1421 [2024-11-00; online 2024-09-27]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre (SMC) [Service]

Sensitive and Specific Droplet Digital PCR Assays for Circulating Tumor HPV DNA: Development, Validation, and Clinical Application in HPV-Associated Cancers.

Qvick A, Andersson E, Oldaeus Almerén A, ..., Karlsson MG, Helenius G

Mol Diagn Ther 28 (6) 835-845 [2024-11-00; online 2024-09-26]

Clinical Genomics Örebro [Technology development]

Real-world assessment of immunogenicity in immunocompromised individuals following SARS-CoV-2 mRNA vaccination: a two-year follow-up of the prospective clinical trial COVAXID.

Chen P, Bergman P, Blennow O, ..., Aleman S, Ljunggren HG

EBioMedicine 109 (-) 105385 [2024-11-00; online 2024-10-11]

Pushing the boundaries of rare disease diagnostics with the help of the first Undiagnosed Hackathon.

Delgado-Vega AM, Cederroth H, Taylan F, ..., Cederroth M, Nordgren A

Nat. Genet. 56 (11) 2287-2294 [2024-11-00; online 2024-10-22]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Gothenburg [Service] Clinical Genomics Stockholm [Service] Clinical Genomics Uppsala [Collaborative] NGI Long read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Collaborative] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Pisolithus microcarpus isolates with contrasting abilities to colonise Eucalyptus grandis exhibit significant differences in metabolic signalling.

Vishwakarma K, Buckley S, Plett JM, ..., Jämtgård S, Plett KL

Fungal Biol 128 (7) 2157-2166 [2024-11-00; online 2024-09-10]

Network analysis reveals age- and virus-specific circuits in nasal epithelial cells of extremely premature infants.

Wisgrill L, Martens A, Kasbauer R, ..., Fyhrquist N, Alenius H

Allergy 79 (11) 3062-3081 [2024-11-00; online 2024-06-19]

Bioinformatics Support for Computational Resources [Service]

Molecular Profiling Defines Three Subtypes of Synovial Sarcoma.

Chen Y, Su Y, Cao X, ..., Li X, de Flon FH

Adv Sci (Weinh) 11 (41) e2404510 [2024-11-00; online 2024-09-10]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Stockholm [Service] Global Proteomics and Proteogenomics [Service]

Local climate, air quality and leaf litter cover shape foliar fungal communities on an urban tree.

Faticov M, Amorim JH, Abdelfattah A, ..., Laforest-Lapointe I, Tack AJM

Ambio 53 (11) 1673-1685 [2024-11-00; online 2024-06-13]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Jag1 insufficiency alters liver fibrosis via T cell and hepatocyte differentiation defects.

Mašek J, Filipovic I, Van Hul N, ..., Dobeš J, Andersson ER

EMBO Mol Med 16 (11) 2946-2975 [2024-11-00; online 2024-10-02]

Bioinformatics Support for Computational Resources [Service]

Genomic and functional characterization of the Atlantic salmon gut microbiome in relation to nutrition and health.

Vera-Ponce de León A, Hensen T, Hoetzinger M, ..., Pope PB, La Rosa SL

Nat Microbiol 9 (11) 3059-3074 [2024-11-00; online 2024-10-14]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Genomic analyses of Streptococcus uberis reveal high diversity but few antibiotic resistance genes

Myrenås M, Fasth C, Waller KP, Pedersen K

Vet. Microbiol. - (-) 110319 [2024-11-00; online 2024-11-00]

Examining the liver-pancreas crosstalk reveals a role for the molybdenum cofactor in β-cell regeneration.

Karampelias C, Băloiu B, Rathkolb B, ..., Hrabě de Angelis M, Andersson O

Life Sci. Alliance 7 (11) e202402771 [2024-11-00; online 2024-08-19]

Bioinformatics Support for Computational Resources [Service] NGI Short read NGI Stockholm (Genomics Production) National Genomics Infrastructure

Depth-specific distribution of bacterial MAGs in permafrost active layer in Ny Ålesund, Svalbard (79°N).

Sipes K, Buongiorno J, Steen AD, ..., Vishnivetskaya TA, Lloyd KG

Syst. Appl. Microbiol. 47 (6) 126544 [2024-11-00; online 2024-08-28]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Characterization of Pediatric Acute Myeloid Leukemia With t(7;12)(q36;p13)

Östlund A, Waraky A, Staffas A, ..., Abrahamsson J, Palmqvist L

Genes Chromosomes Cancer 63 (11) - [2024-11-00; online 2024-11-07]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Androgen receptor pathway inhibitors and taxanes in metastatic prostate cancer: an outcome-adaptive randomized platform trial.

De Laere B, Crippa A, Discacciati A, ..., Grönberg H, Lindberg J

Nat. Med. 30 (11) 3291-3302 [2024-11-00; online 2024-08-20]

Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Clinical Genomics Stockholm [Service]

An ancient ecospecies of Helicobacter pylori.

Tourrette E, Torres RC, Svensson SL, ..., Thorell K, Falush D

Nature 635 (8037) 178-185 [2024-11-00; online 2024-10-16]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Gothenburg [Collaborative]

A new species of Erinaceusyllis (Annelida: Syllidae) discovered at a wood-fall in the eastern Clarion-Clipperton Zone, central Pacific Ocean.

Nilsson CL, Wiklund H, Glover AG, Bribiesca-Contreras G, Dahlgren TG

Deep Sea Research Part I: Oceanographic Research Papers - (-) 104415 [2024-11-00; online 2024-11-00]

Integrated Microscopy Technologies Gothenburg [Service]

Orthopteran Neo-Sex Chromosomes Reveal Dynamics of Recombination Suppression and Evolution of Supergenes.

Jayaprasad S, Peona V, Ellerstrand SJ, ..., Schielzeth H, Palacios-Gimenez OM

Mol. Ecol. - (-) e17567 [2024-10-30; online 2024-10-30]

Bioinformatics Support for Computational Resources [Service] NGI Long read [Collaborative] NGI Stockholm (Genomics Applications) [Collaborative] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

High-parametric protein maps reveal the spatial organization in early-developing human lung.

Sariyar S, Sountoulidis A, Hansen JN, ..., Lundberg E, Ayoglu B

Nat Commun 15 (1) 9381 [2024-10-30; online 2024-10-30]

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Nat Commun 15 (1) 9343 [2024-10-29; online 2024-10-29]

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Nat Commun 15 (1) 9286 [2024-10-28; online 2024-10-28]

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ChemistryOpen - (-) e202400069 [2024-10-25; online 2024-10-25]

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Microbiome 12 (1) 218 [2024-10-24; online 2024-10-24]

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Cells 13 (21) 1764 [2024-10-24; online 2024-10-24]

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J Clin Immunol 45 (1) 31 [2024-10-23; online 2024-10-23]

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Ghantous A, Nusslé SG, Nassar FJ, ..., Munthe-Kaas MC, Herceg Z

Mol. Cancer 23 (1) 238 [2024-10-23; online 2024-10-23]

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Three Novel Spider Genomes Unveil Spidroin Diversification and Hox Cluster Architecture: Ryuthela nishihirai (Liphistiidae), Uloborus plumipes (Uloboridae) and Cheiracanthium punctorium (Cheiracanthiidae).

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Mol Ecol Resour - (-) e14038 [2024-10-22; online 2024-10-22]

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Correia SP, Moedas MF, Taylor LS, ..., Wedell A, Wredenberg A

JCI Insight 9 (20) - [2024-10-22; online 2024-10-22]

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Boisen G, Brogårdh-Roth S, Neilands J, ..., Carda-Diéguez M, Davies JR

Front Oral Health 5 (-) 1475361 [2024-10-22; online 2024-10-22]

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Cancer Risk in Patients With Muscular Dystrophy and Myotonic Dystrophy: A Register-Based Cohort Study.

Maya-González C, Tettamanti G, Taylan F, ..., Sejersen T, Nordgren A

Neurology 103 (8) e209883 [2024-10-22; online 2024-09-19]

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Theodoropoulou E, Pierozan P, Marabita F, Höglund A, Karlsson O

Chemosphere - (-) 143605 [2024-10-21; online 2024-10-21]

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Nat. Methods - (-) - [2024-10-21; online 2024-10-21]

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Biochimie - (-) - [2024-10-18; online 2024-10-18]

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Olsson M, Storm R, Björn L, ..., Liebi M, Matic A

Commun Mater 5 (1) - [2024-10-18; online 2024-10-18]

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Science 386 (6719) eadn9083 [2024-10-18; online 2024-10-18]

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Nat Commun 15 (1) 8992 [2024-10-18; online 2024-10-18]

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Br J Anaesth - (-) - [2024-10-18; online 2024-10-18]

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Sci Rep 14 (1) 24512 [2024-10-18; online 2024-10-18]

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Nat Commun 15 (1) 8941 [2024-10-17; online 2024-10-17]

Autoimmunity and Serology Profiling [Collaborative]

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J Transl Med 22 (1) 947 [2024-10-17; online 2024-10-17]

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MBio 15 (10) e0156924 [2024-10-16; online 2024-09-19]

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Hellman U, Rosendal E, Lehrstrand J, ..., Överby AK, Lenman A

MBio 15 (10) e0130324 [2024-10-16; online 2024-09-20]

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Modulating protein unfolding and refolding via the synergistic association of an anionic and a nonionic surfactant.

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Journal of Colloid and Interface Science 672 (-) 244-255 [2024-10-15; online 2024-05-22]

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Sjövall D, Ghosh S, Fernandez-Fuentes N, ..., Guibentif C, Jaako P

Cell Rep 43 (11) 114864 [2024-10-15; online 2024-10-15]

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Commun Biol 7 (1) 1332 [2024-10-15; online 2024-10-15]

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NPJ Biodivers 3 (1) 31 [2024-10-15; online 2024-10-15]

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Milesi P, Kastally C, Dauphin B, ..., Pyhäjärvi T, GenTree Consortium

Nat Commun 15 (1) 8538 [2024-10-14; online 2024-10-14]

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Nucleic Acids Res. 52 (18) 11266-11282 [2024-10-14; online 2024-08-01]

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Rheumatology (Oxford) - (-) - [2024-10-14; online 2024-10-14]

Autoimmunity and Serology Profiling [Collaborative]

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ACS Appl Mater Interfaces - (-) - [2024-10-13; online 2024-10-13]

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Health Informatics J 30 (4) 14604582241290725 [2024-10-12; online 2024-10-12]

Clinical Genomics Stockholm [Collaborative]

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Ermann Lundberg L, Mata Forsberg M, Lemanczyk J, ..., Roos S, Håkansson S

Microorganisms 12 (10) - [2024-10-12; online 2024-10-12]

Genomic Analyses of Methicillin-Resistant Staphylococcus pseudintermedius from Companion Animals Reveal Changing Clonal Populations, Multidrug Resistance, and Virulence

Myrenås M, Pedersen K, Windahl U

Antibiotics (Basel) 13 (10) 962 [2024-10-12; online 2024-10-12]

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Nat Commun 15 (1) 8724 [2024-10-09; online 2024-10-09]

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Wellcome Open Res 9 (-) 575 [2024-10-09; online 2024-10-09]

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Nat Commun 15 (1) 8759 [2024-10-09; online 2024-10-09]

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Bradley F, Stern A, Franzén Boger M, ..., Fowke KR, Broliden K

Front Endocrinol (Lausanne) 15 (-) 1454006 [2024-10-08; online 2024-10-08]

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Chemical Exposomics in Human Plasma by Lipid Removal and Large-Volume Injection Gas Chromatography–High-Resolution Mass Spectrometry

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Environ. Sci. Technol. 58 (40) 17592-17605 [2024-10-08; online 2024-09-24]

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Chemistry - (-) e202403411 [2024-10-07; online 2024-10-07]

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BMC Genomics 25 (1) 938 [2024-10-07; online 2024-10-07]

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Li D, Liu Z, Zhang L, ..., Sommar P, Xu Landén N

Nat Commun 15 (1) 8637 [2024-10-05; online 2024-10-05]

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Elucidating Thermothielavioides terrestris secretome changes for improved saccharification of mild steam-pretreated spruce.

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Biotechnol Biofuels Bioprod 17 (1) 127 [2024-10-05; online 2024-10-05]

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Techameena P, Feng X, Zhang K, Hadjab S

Nat Commun 15 (1) 8585 [2024-10-04; online 2024-10-04]

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The Population History of Domestic Sheep Revealed by Paleogenomes.

Kaptan D, Atağ G, Vural KB, ..., Somel M, Özer F

Mol. Biol. Evol. 41 (10) - [2024-10-04; online 2024-10-23]

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Inflammatory and cardiovascular markers in placenta following SARS-CoV-2 infection during pregnancy: A Swedish prospective cohort study.

Östling H, Lodefalk M, Bergman L, ..., Backman H, Kruse R

Placenta 158 (-) 78-88 [2024-10-04; online 2024-10-04]

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Pettersson C, Wu R, Demirel I

Sci Rep 14 (1) 23030 [2024-10-03; online 2024-10-03]

Early-Life Hygiene-Related Factors and Risk of Inflammatory Bowel Disease: A Scandinavian Birth Cohort Study.

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Inflamm Bowel Dis 30 (10) 1820-1830 [2024-10-03; online 2023-11-03]

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An interlaboratory proficiency test using metagenomic sequencing as a diagnostic tool for the detection of RNA viruses in swine fecal material.

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Microbiol Spectr 12 (10) e0420823 [2024-10-03; online 2024-08-20]

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Alzheimers Res Ther 16 (1) 213 [2024-10-02; online 2024-10-02]

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Spatial multiomic insights into acute cocaine exposure

Nezhyva M, Shahen-Zoabi S, Kabirova M, ..., Margulis K, Jansson ET

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Spatial Transcriptome Mapping of the Desmoplastic Growth Pattern of Colorectal Liver Metastases by In Situ Sequencing Reveals a Biologically Relevant Zonation of the Desmoplastic Rim.

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Clin. Cancer Res. 30 (19) 4517-4529 [2024-10-01; online 2024-07-26]

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J. Clin. Invest. 134 (19) - [2024-10-01; online 2024-10-01]

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Sci. Total Environ. 945 (-) 174183 [2024-10-01; online 2024-06-21]

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DockQ v2: improved automatic quality measure for protein multimers, nucleic acids, and small molecules.

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Bioinformatics 40 (10) - [2024-10-01; online 2024-09-30]

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Environ. Sci. Technol. 58 (39) 17454-17463 [2024-10-01; online 2024-09-18]

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Lancet Microbe - (-) 100998 [2024-10-01; online 2024-10-01]

Unraveling GRIA1 neurodevelopmental disorders: Lessons learned from the p.(Ala636Thr) variant.

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Clin. Genet. 106 (4) 427-436 [2024-10-00; online 2024-06-18]

Sex estimation using long bones in the largest burial site of the Copper Age: Linear discriminant analysis and random forest

Díaz-Navarro S, Díez-Hermano S, Rojo-Guerra MA, ..., Gunther T, Uriarte MH

Journal of Archaeological Science: Reports 58 (-) 104730 [2024-10-00; online 2024-10-00]

Personalized mixture toxicity testing: A proof-of-principle in vitro study evaluating the steroidogenic effects of reconstructed contaminant mixtures measured in blood of individual adults.

Strand D, Lundgren B, Bergdahl IA, Martin JW, Karlsson O

Environ Int 192 (-) 108991 [2024-10-00; online 2024-08-30]

Drug Discovery and Development (DDD) [Collaborative]

Multi-omics profiling to identify early plasma biomarkers in pre-diagnostic pancreatic ductal adenocarcinoma: a nested case-control study.

Borgmästars E, Ulfenborg B, Johansson M, ..., Lubovac-Pilav Z, Sund M

Transl Oncol 48 (-) 102059 [2024-10-00; online 2024-07-16]

Affinity Proteomics Uppsala [Service] Swedish Metabolomics Centre (SMC) [Service]

Molecular Subtypes Are Associated With Clinical Benefit in Cisplatin-Treated Metastatic Urothelial Cancer Patients.

Holmsten K, Sjödahl G, Abrahamsson J, ..., Liedberg F, Ullén A

JCO Precision Oncology 8 (-) e2400209 [2024-10-00; online 2024-10-02]

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Horváth V, Garza R, Jönsson ME, ..., Douse CH, Jakobsson J

Nat. Struct. Mol. Biol. 31 (10) 1543-1556 [2024-10-00; online 2024-06-04]

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Renewable Energy 233 (-) 121148 [2024-10-00; online 2024-10-00]

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Mov Disord 39 (10) 1881-1885 [2024-10-00; online 2024-05-26]

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New Phytol. 244 (1) 219-234 [2024-10-00; online 2024-08-07]

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Virus Res. 348 (-) 199434 [2024-10-00; online 2024-07-19]

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Industrial Crops and Products 218 (-) 118858 [2024-10-00; online 2024-10-00]

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Dyrdak R, Hodcroft EB, Broddesson S, ..., Neher RA, Albert J

Euro Surveill. 29 (41) - [2024-10-00; online 2024-10-11]

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Ocul Surf 34 (-) 225-234 [2024-10-00; online 2024-08-08]

Comparative proteomic analyses of potato leaves from field-grown plants grown under extremely long days.

Resjö S, Willforss J, Large A, ..., Levander F, Andreasson E

Plant Physiol Biochem 215 (-) 109032 [2024-10-00; online 2024-08-10]

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Benchmarking long-read sequencing strategies for obtaining ASV-resolved rRNA operons from environmental microeukaryotes.

Overgaard CK, Jamy M, Radutoiu S, Burki F, Dueholm MKD

Mol Ecol Resour 24 (7) e13991 [2024-10-00; online 2024-07-09]

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Wikström Shemer D, Mostafaei S, Tang B, ..., Fall T, Hägg S

Geroscience 46 (5) 5003-5014 [2024-10-00; online 2024-06-27]

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A randomized controlled cross-over trial investigating the acute inflammatory and metabolic response after meals based on red meat, fatty fish, or soy protein: the postprandial inflammation in rheumatoid arthritis (PIRA) trial.

Hulander E, Bärebring L, Winkvist A, Gjertsson I, Lindqvist HM

Eur J Nutr 63 (7) 2631-2642 [2024-10-00; online 2024-06-27]

"Metagenomics reveal the potential for geosmin and 2-methylisoborneol production across multiple bacterial phyla in recirculating aquaculture systems".

Zheng D, Wilén BM, Öberg O, Wik T, Modin O

Environ. Microbiol. 26 (10) e16696 [2024-10-00; online 2024-10-09]

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RNA silencing is a key regulatory mechanism in the biocontrol fungus Clonostachys rosea-wheat interactions.

Piombo E, Vetukuri RR, Konakalla NC, ..., Karlsson M, Dubey M

BMC Biol. 22 (1) 219 [2024-09-30; online 2024-09-30]

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BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection.

Rajan A, Gallego P, Dolan B, ..., Simrén M, Pelaseyed T

Gut Microbes 16 (1) 2409247 [2024-09-30; online 2024-09-30]

A research data management (RDM) community for ELIXIR.

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F1000Res 13 (-) - [2024-09-30; online 2024-09-30]

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SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis.

Murga M, Lopez-Pernas G, Soliva R, ..., Orozco M, Fernández-Capetillo O

Cell Death Dis 15 (9) 694 [2024-09-28; online 2024-09-28]

NiO thin films fabricated using spray-pyrolysis technique: structural and optical characterization and ultrafast charge dynamics studies

Das L, Canto-Aguilar EJ, Tapani T, ..., Gracia-Espino E, Maccaferri N

J. Phys. D: Appl. Phys. 57 (38) 385303 [2024-09-27; online 2024-07-02]

Multiomic biomarkers after cardiac arrest.

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Intensive Care Med Exp 12 (1) 83 [2024-09-27; online 2024-09-27]

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Maity R, Zhang X, Liberati FR, ..., Aínsa JA, Sancho J

Elife 13 (-) - [2024-09-27; online 2024-09-27]

Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases.

Thorsson H, Henningsson R, Puente-Moncada N, ..., Lilljebjörn H, Fioretos T

Blood 144 (13) 1399-1411 [2024-09-26; online 2024-07-05]

Harnessing Light for G-Quadruplex Modulation: Dual Isomeric Effects of an Ortho-Fluoroazobenzene Derivative.

Dudek M, López-Pacios L, Sabouri N, ..., Martinez-Fernandez L, Deiana M

J Phys Chem Lett 15 (38) 9757-9765 [2024-09-26; online 2024-09-17]

Chemical Biology Consortium Sweden (CBCS) [Service]

CDK4 is co-amplified with either TP53 promoter gene fusions or MDM2 through distinct mechanisms in osteosarcoma.

Saba KH, Difilippo V, Styring E, ..., Baumhoer D, Nord KH

npj Genom. Med. 9 (1) 42 [2024-09-25; online 2024-09-25]

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Analyzing Fusion Pore Dynamics and Counting the Number of Acetylcholine Molecules Released by Exocytosis.

Wang Y, Pradhan A, Gupta P, ..., Zetterberg H, Cans AS

J. Am. Chem. Soc. 146 (38) 25902-25906 [2024-09-25; online 2024-09-11]

Integrated Microscopy Technologies Gothenburg [Service]

Hematopoietic cells emerging from hemogenic endothelium exhibit lineage-specific oxidative stress responses.

Biezeman H, Nubiè M, Oburoglu L

J. Biol. Chem. 300 (11) 107815 [2024-09-24; online 2024-09-24]

A Versatile and Upgraded Version of the LundTax Classification Algorithm Applied to Independent Cohorts.

Cotillas EA, Bernardo C, Veerla S, ..., Sjödahl G, Eriksson P

J Mol Diagn - (-) - [2024-09-24; online 2024-09-24]

Enrichment Reveals Extensive Integration of Hepatitis B Virus DNA in Hepatitis Delta Virus-Infected Patients.

Ringlander J, Strömberg LG, Stenbäck JB, ..., Rydell GE, Lindh M

J. Infect. Dis. 230 (3) e684-e693 [2024-09-23; online 2024-01-25]

PITAR, a DNA damage-inducible cancer/testis long noncoding RNA, inactivates p53 by binding and stabilizing TRIM28 mRNA.

Jana S, Mondal M, Mahale S, ..., Kanduri C, Somasundaram K

Elife 12 (-) - [2024-09-20; online 2024-09-20]

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Edelbroek B, Westholm JO, Bergquist J, Söderbom F

iScience 27 (9) 110659 [2024-09-20; online 2024-08-03]

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Cancer associated variant enrichment CAVE, a gene agnostic approach to identify low burden variants in chronic lymphocytic leukemia.

Yaacov A, Lazarian G, Pandzic T, ..., Rosenberg S, Soussi T

Sci Rep 14 (1) 21962 [2024-09-20; online 2024-09-20]

Clinical Genomics Uppsala [Collaborative]

Crystal structure validation of verinurad via proton-detected ultra-fast MAS NMR and machine learning.

Torodii D, Holmes JB, Moutzouri P, ..., Schantz S, Emsley L

Faraday Discuss. - (-) - [2024-09-19; online 2024-09-19]

Swedish NMR Centre (SNC) [Technology development]

Cooperative folding as a molecular switch in an evolved antibody binder.

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J. Biol. Chem. 300 (11) 107795 [2024-09-19; online 2024-09-19]

Metabolic Phenotyping from Whole-Blood Responses to a Standardized Exercise Test May Discriminate for Physiological, Performance, and Illness Outcomes: A Pilot Study in Highly-Trained Cross-Country Skiers.

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Sports Med Open 10 (1) 99 [2024-09-18; online 2024-09-18]

Claustrum and dorsal endopiriform cortex complex cell-identity is determined by Nurr1 and regulates hallucinogenic-like states in mice.

Mantas I, Flais I, Masarapu Y, ..., Perlmann T, Svenningsson P

Nat Commun 15 (1) 8176 [2024-09-18; online 2024-09-18]

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The European Reference Genome Atlas: piloting a decentralised approach to equitable biodiversity genomics.

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NPJ Biodivers 3 (1) 28 [2024-09-17; online 2024-09-17]

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Monitoring SARS-CoV-2 IgA, IgM and IgG antibodies in dried blood and saliva samples using antibody proximity extension assays (AbPEA).

Wang M, Kamali-Moghaddam M, Löf L, ..., Landegren U, Zhao H

Sci Rep 14 (1) 21655 [2024-09-17; online 2024-09-17]

Affinity Proteomics Uppsala [Technology development]

Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood.

Sdougkou K, Papazian S, Bonnefille B, ..., Martin LJ, Martin JW

Environ. Sci. Technol. 58 (37) 16302-16315 [2024-09-17; online 2024-09-05]

Genetic differentiation and diversity do not explain variation in heterosis or inbreeding depression: empirical evidence from a long-lived iteroparous plant

Söderquist L, Karrenberg S, Sletvold N

Conserv Genet - (-) - [2024-09-17; online 2024-09-17]

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Unraveling the Genetics of Shared Clinical and Serological Manifestations in Patients With Systemic Inflammatory Autoimmune Diseases.

Bianchi M, Kozyrev SV, Notarnicola A, ..., Lindblad-Toh K, with the DISSECT consortium and the ImmunoArray consortium

Arthritis & rheumatology (Hoboken, N.J.) - (-) - [2024-09-16; online 2024-09-16]

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Mosaic loss of Y chromosome and the association to mortality in Danish men aged 56-100 years.

Hozakowska-Roszkowska DM, Mengel-From J, Hristozova TK, ..., Röttger R, Nygaard M

Mech Ageing Dev 222 (-) 111979 [2024-09-16; online 2024-09-16]

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An Improved Chromosome-scale Genome Assembly and Population Genetics resource for Populus tremula.

Robinson KM, Schiffthaler B, Liu H, ..., Ingvarsson PK, Street NR

Physiol Plantarum 176 (5) e14511 [2024-09-16; online 2024-09-16]

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The CHCHD2-CHCHD10 protein complex is modulated by mitochondrial dysfunction and alters lipid homeostasis in the mouse brain

Gerlach J, Pireddu P, Zhang X, ..., Svenningsson P, Filograna R

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Solution-Processable Bismuthene Nanosheets for Ultrasensitive Sensing of Heavy Metal Ions via Anodic Stripping Voltammetry

Adeniyi KO, Manavalan G, Zainelabdin A, Mikkola JP, Tesfalidet S

ACS Appl. Nano Mater. 7 (17) 20217-20228 [2024-09-13; online 2024-08-30]

Exposure of Colon-Derived Epithelial Monolayers to Fecal Luminal Factors from Patients with Colon Cancer and Ulcerative Colitis Results in Distinct Gene Expression Patterns.

Magnusson MK, Bas Forsberg A, Verveda A, ..., Simrén M, Öhman L

Int J Mol Sci 25 (18) - [2024-09-13; online 2024-09-13]

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Early-Life Diet Diversity and the Subsequent Risk of Inflammatory Bowel Disease: Findings From Two Scandinavian Birth Cohorts.

Guo A, Ludvigsson J, Hård Af Segerstad EM, ..., Størdal K, Mårild K

Inflamm Bowel Dis - (-) - [2024-09-13; online 2024-09-13]

Chromosome-level genome assembly of the morabine grasshopper Vandiemenella viatica19.

Li X, Jayaprasad S, Einarsdottir E, ..., Kawakami T, Palacios-Gimenez OM

Sci Data 11 (1) 997 [2024-09-12; online 2024-09-12]

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Aberrant growth and expansion in Penium margaritaceum triggered by disruption of microtubules and the cell wall.

LoRicco JG, Malone S, Becker A, ..., Epstein R, Domozych DS

J. Exp. Bot. - (-) - [2024-09-12; online 2024-09-12]

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Prokaryotic morphological features and maintenance activities governed by seasonal productivity conditions.

Verma A, Amnebrink D, Lee CC, ..., Pinhassi J, Wikner J

FEMS Microbiol. Ecol. - (-) - [2024-09-11; online 2024-09-11]

Integrated Microscopy Technologies Umeå [Collaborative]

Probing erythrocytes as sensitive and reliable sensors of metabolic disturbances in the crosstalk between childhood obesity and insulin resistance: findings from an observational study, in vivo challenge tests, and ex vivo incubation assays.

González-Domínguez Á, Savolainen O, Domínguez-Riscart J, ..., Lechuga-Sancho A, González-Domínguez R

Cardiovasc Diabetol 23 (1) 336 [2024-09-11; online 2024-09-11]

Chalmers Mass Spectrometry Infrastructure [Collaborative]

Enrichment of Cis-Acting Regulatory Elements in Differentially Methylated Regions Following Lipopolysaccharide Treatment of Bovine Endometrial Epithelial Cells.

Jhamat N, Guo Y, Han J, ..., Andersson G, Niazi A

Int J Mol Sci 25 (18) - [2024-09-11; online 2024-09-11]

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Aging is associated with functional and molecular changes in distinct hematopoietic stem cell subsets.

Su TY, Hauenstein J, Somuncular E, ..., Månsson R, Luc S

Nat Commun 15 (1) 7966 [2024-09-11; online 2024-09-11]

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Inherited human RelB deficiency impairs innate and adaptive immunity to infection.

Le Voyer T, Maglorius Renkilaraj MRL, Moriya K, ..., Tangye SG, Puel A

Proc. Natl. Acad. Sci. U.S.A. 121 (37) e2321794121 [2024-09-10; online 2024-09-04]

Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma.

Nagarajan D, Parracho RT, Corujo D, ..., Buschbeck M, Mao Y

J. Clin. Invest. 134 (21) - [2024-09-10; online 2024-09-10]

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Lobo V, Nowak I, Fernandez C, ..., Angeletti D, Sarshad AA

Nucleic Acids Res. 52 (16) 9917-9935 [2024-09-09; online 2024-07-12]

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Transient colonizing microbes promote gut dysbiosis and functional impairment.

Lee S, Meslier V, Bidkhori G, ..., Uhlen M, Shoaie S

NPJ Biofilms Microbiomes 10 (1) 80 [2024-09-08; online 2024-09-08]

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MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles.

Kammann T, Cai C, Sekine T, ..., Buggert M, Sandberg JK

Sci Immunol 9 (99) eadn2362 [2024-09-06; online 2024-09-06]

Defining the Soluble and Extracellular Vesicle Protein Compartments of Plasma Using In-Depth Mass Spectrometry-Based Proteomics.

Sharma N, Angori S, Sandberg A, ..., Eriksson H, Pernemalm M

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Compound heterozygosity for two variants in BMP5 in human skeletal dysostosis with atrioventricular septal defect.

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The Influence of Disulfide, Thioacetal and Lanthionine-Bridges on the Conformation of a Macrocyclic Peptide.

Darling WTP, Wieske LHE, Cook DT, ..., Erdélyi M, Tabor AB

Chemistry 30 (50) e202401654 [2024-09-05; online 2024-08-20]

Structure of the iminium reaction intermediate in an engineered aldolase explains the carboligation activity toward arylated ketones and aldehydes.

Hebert H, Sönmez E, Purhonen P, Widersten M

Structure 32 (9) 1322-1326.e4 [2024-09-05; online 2024-07-15]

Blood based metabolic markers of glioma from pre-diagnosis to surgery.

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Sci Rep 14 (1) 20680 [2024-09-05; online 2024-09-05]

Male-biased recombination at chromosome ends in a songbird revealed by precisely mapping crossover positions.

Zhang H, Lundberg M, Ponnikas S, Hasselquist D, Hansson B

G3 (Bethesda) 14 (9) - [2024-09-04; online 2024-07-10]

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Immune system adaptation during gender-affirming testosterone treatment

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Nature 633 (-) 155-164 [2024-09-04]

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Urine metabolomic profiles of autism and autistic traits-A twin study.

Arora A, Mastropasqua F, Bölte S, Tammimies K

PLoS ONE 19 (9) e0308224 [2024-09-03; online 2024-09-03]

Temporal dynamics of faster neo-Z evolution in butterflies.

Höök L, Vila R, Wiklund C, Backström N

Evolution 78 (9) 1554-1567 [2024-09-03; online 2024-05-30]

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In silico gepotidacin target mining among 33 213 global Neisseria gonorrhoeae genomes from 1928 to 2023 combined with gepotidacin MIC testing of 22 gonococcal isolates with different GyrA and ParC substitutions.

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J. Bone Miner. Res. 39 (9) 1315-1326 [2024-09-02; online 2024-08-10]

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Protective Non-neutralizing anti-N-terminal Domain mAb Maintains Fc-mediated Function against SARS-COV-2 Variants up to BA.2.86-JN.1 with Superfluous In Vivo Protection against JN.1 Due to Attenuated Virulence.

Izadi A, Godzwon M, Söderlund Strand A, ..., Ohlin M, Nordenfelt P

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Pacoste L, Ignat'ev VM, Dominiak PM, Zou X

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Li Y, Pacoste LC, Gu W, ..., Xu H, Nanson JD

Acta Crystallogr D Struct Biol 80 (Pt 9) 699-712 [2024-09-01; online 2024-09-04]

Elevated carbohydrate antigen 125 (CA125) is associated with incident heart failure and mortality in acute coronary syndrome.

Yndigegn T, Gu T, Grufman H, ..., Goncalves I, Schiopu A

ESC Heart Failure - (-) - [2024-09-01; online 2024-09-01]

A Drug Discovery Pipeline for MAPK/ERK Pathway Inhibitors in Caenorhabditis elegans.

Gorgoń S, Billing O, Eriksson AU, Hemmingsson O

Cancer Res Commun 4 (9) 2454-2462 [2024-09-01; online 2024-08-31]

Chemical Biology Consortium Sweden (CBCS) [Collaborative]

pH‐Responsive Virus‐Based Colloidal Crystals for Advanced Material Platforms

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Transcriptomic and functional analyses on a Botrytis cinerea multidrug-resistant (MDR) strain provides new insights into the potential molecular mechanisms of MDR and fitness.

Sofianos G, Piombo E, Dubey M, ..., Karaoglanidis G, Tzelepis G

Mol. Plant Pathol. 25 (9) e70004 [2024-09-00; online 2024-09-08]

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The PerioGene North Study Uncovers Serum Proteins Related to Periodontitis.

Wänman M, Betnér S, Esberg A, ..., Kindstedt E, Lundberg P

J Dent Res 103 (10) 999-1007 [2024-09-00; online 2024-08-05]

The CCTδ subunit of the molecular chaperone CCT is required for correct localisation of p150Glued to spindle poles during mitosis.

Córdoba-Beldad CM, Grantham J

Eur J Cell Biol 103 (3) 151430 [2024-09-00; online 2024-06-15]

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Systems genetic analysis of lignin biosynthesis in Populus tremula.

Luomaranta M, Grones C, Choudhary S, ..., Street NR, Tuominen H

New Phytol. 243 (6) 2157-2174 [2024-09-00; online 2024-07-28]

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Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs.

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Species-genetic diversity correlation in a metacommunity of urban pond invertebrates

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Basic and Applied Ecology 79 (-) 114-122 [2024-09-00; online 2024-09-00]

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Speciation in savanna birds in South America: The case of the Least Nighthawk Chordeiles pusillus (Aves: Caprimulgidae) in and out of the Amazon.

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Points2Regions: Fast, interactive clustering of imaging-based spatial transcriptomics data.

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Cytometry A 105 (9) 677-687 [2024-09-00; online 2024-07-03]

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J Mol Diagn 26 (9) 792-804 [2024-09-00; online 2024-06-24]

New finds of European bison identified through the systematic DNA-based species identification of archaeological remains of large bovines from Scandinavia

Rosengren E, Rossi C, Heino MT, Sinding MHS

Journal of Archaeological Science: Reports 57 (-) 104668 [2024-09-00; online 2024-09-00]

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Marina H, Nielsen PP, Fikse WF, Rönnegård L

Applied Animal Behaviour Science 278 (-) 106366 [2024-09-00; online 2024-09-00]

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Animal Reproduction Science 268 (-) 107569 [2024-09-00; online 2024-07-30]

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Longitudinal changes in cardiovascular disease-related proteins in welders.

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Immune system adaptation during gender-affirming testosterone treatment.

Lakshmikanth T, Consiglio C, Sardh F, ..., Landegren N, Brodin P

Nature 633 (8028) 155-164 [2024-09-00; online 2024-09-04]

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Hop stunt viroid infection induces heterochromatin reorganization.

Marquez-Molins J, Cheng J, Corell-Sierra J, ..., Gomez G, Martinez G

New Phytol. 243 (6) 2351-2367 [2024-09-00; online 2024-07-18]

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Genome-Wide Association Study of Obsessive-Compulsive Symptoms including 33,943 individuals from the general population.

Strom NI, Burton CL, Iyegbe C, ..., Smit DJA, Arnold PD

Mol. Psychiatry 29 (9) 2714-2723 [2024-09-00; online 2024-03-28]

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Dantrolene corrects cellular disease features of Darier disease and may be a novel treatment.

Hunt M, Wang N, Pupinyo N, ..., Bachar-Wikstrom E, Wikstrom JD

EMBO Mol Med 16 (9) 1986-2001 [2024-09-00; online 2024-07-26]

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Contemporary intergeneric hybridization and backcrossing among birds-of-paradise.

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Evolution Letters 8 (5) 680-694 [2024-09-00; online 2024-06-08]

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Sci Adv 10 (35) eadp8625 [2024-08-30; online 2024-08-28]

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DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor.

Pandiloski N, Horváth V, Karlsson O, ..., Jakobsson J, Douse CH

Nat Commun 15 (1) 7534 [2024-08-30; online 2024-08-30]

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Conference report: the first bacterial genome sequencing pan-European network conference.

Germuskova Z, Sosa E, Lagos AC, ..., Mölling P, Egli A

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The Crosstalk Analysis between mPSCs and Panc1 Cells Identifies CCN1 as a Positive Regulator of Gemcitabine Sensitivity in Pancreatic Cancer Cells.

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Expression of inducible nitric oxide synthase, nitrotyrosine, eosinophilic peroxidase, eotaxin-3, and galectin-3 in patients with gastroesophageal reflux disease, eosinophilic esophagitis, and in healthy controls: a semiquantitative image analysis of 3,3'-diaminobenzidine-stained esophageal biopsies.

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Nat Commun 15 (1) 7510 [2024-08-29; online 2024-08-29]

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A charged tail on anti-α-Synuclein antibodies does not enhance their affinity to α-Synuclein fibrils.

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PLoS ONE 19 (8) e0308521 [2024-08-29; online 2024-08-29]

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Nat Commun 15 (1) 7422 [2024-08-28; online 2024-08-28]

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JAMA Psychiatry - (-) - [2024-08-28; online 2024-08-28]

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Antimicrob Agents Chemother - (-) - [2024-08-28; online 2024-08-28]

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González-Domínguez Á, Domínguez-Riscart J, Savolainen O, ..., Landberg R, González-Domínguez R

Cardiovasc Diabetol 23 (1) 315 [2024-08-27; online 2024-08-27]

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Nat Commun 15 (1) 7177 [2024-08-26; online 2024-08-26]

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Intensified, Kilogram-Scaled, and Environment-Friendly: Chemoenzymatic Synthesis of Bio-Based Acylated Hydroxystyrenes.

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ACS Sustainable Chem. Eng. 12 (34) 12869-12878 [2024-08-26; online 2024-08-15]

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JOSS 9 (100) 6869 [2024-08-26; online 2024-08-26]

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Anal Bioanal Chem - (-) - [2024-08-24; online 2024-08-24]

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Breton G, Barham L, Mudenda G, ..., Schlebusch CM, Jakobsson M

Nat Commun 15 (1) 7307 [2024-08-24; online 2024-08-24]

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Cell Commun Signal 22 (1) 411 [2024-08-23; online 2024-08-23]

Oral nicotinamide provides robust, dose-dependent structural and metabolic neuroprotection of retinal ganglion cells in experimental glaucoma.

Cimaglia G, Tribble JR, Votruba M, Williams PA, Morgan JE

Acta Neuropathol Commun 12 (1) 137 [2024-08-23; online 2024-08-23]

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Science 385 (6711) 892-898 [2024-08-23; online 2024-08-22]

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CDK8 of the mediator kinase module connects leaf development to the establishment of correct stomata patterning by regulating the levels of the transcription factor SPEECHLESS (SPCH).

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Plant Cell Environ. - (-) - [2024-08-23; online 2024-08-23]

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Hydrazide-based reactive matrices for the sensitive detection of aldehydes and ketones by MALDI mass spectrometry imaging.

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Chem. Commun. (Camb.) 60 (69) 9238-9241 [2024-08-22; online 2024-08-22]

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Heavy-atom-free π-twisted photosensitizers for fluorescence bioimaging and photodynamic therapy.

Sánchez DP, Morice K, Mutovska MG, ..., Cabanetos C, Deiana M

J Mater Chem B 12 (33) 8107-8121 [2024-08-22; online 2024-08-22]

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Blood 144 (8) 873-887 [2024-08-22; online 2024-07-03]

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Karlsson A, Alarcón LA, Piñeiro-Iglesias B, ..., Jin T, Karlsson R

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Song J, Li Z, Zhou L, ..., Rasmussen LJ, Dai F

Nat Commun 15 (1) 7144 [2024-08-21; online 2024-08-21]

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The involvement of cyclotides in the heavy metal tolerance of Viola spp.

Sychta K, Słomka A, Shariatgorji R, ..., Göransson U, Slazak B

Sci Rep 14 (1) 19306 [2024-08-20; online 2024-08-20]

Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates.

Meng Z, Saei AA, Gharibi H, ..., Gaetani M, Zubarev RA

Anal. Chem. 96 (33) 13533-13541 [2024-08-20; online 2024-08-07]

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The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.

Swisa A, Kieckhaefer J, Daniel SG, ..., Bittinger K, Kaestner KH

Dev. Cell 59 (16) 2069-2084.e8 [2024-08-19; online 2024-05-30]

Host-pathogen interactions in the Plasmodium-infected mouse liver at spatial and single-cell resolution.

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Nat Commun 15 (1) 7105 [2024-08-19; online 2024-08-19]

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Type I Interferon Autoantibodies Correlate With Cellular Immune Alterations in Severe COVID-19.

Strunz B, Maucourant C, Mehta A, ..., Björkström NK, Karolinska KI/K COVID-19 Study Group

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Sci Adv 10 (33) eadn0597 [2024-08-16; online 2024-08-14]

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Motor innervation directs the correct development of the mouse sympathetic nervous system.

Erickson AG, Motta A, Kastriti ME, ..., Bonanomi D, Adameyko I

Nat Commun 15 (1) 7065 [2024-08-16; online 2024-08-16]

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Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection.

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iScience 27 (8) 110555 [2024-08-16; online 2024-07-20]

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Schaus SR, Vasconcelos Pereira G, Luis AS, ..., Hansson GC, Martens EC

MBio 15 (8) e0003924 [2024-08-14; online 2024-07-08]

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Wågström P, Hjorth M, Appelgren D, ..., Ernerudh J, Nyström S

Front Immunol 15 (-) 1442749 [2024-08-14; online 2024-08-14]

Escherichia coli in urban marine sediments: interpreting virulence, biofilm formation, halotolerance, and antibiotic resistance to infer contamination or naturalization.

Erb IK, Suarez C, Frank EM, ..., Lindberg E, Paul CJ

FEMS Microbes 5 (-) xtae024 [2024-08-14; online 2024-08-14]

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Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall.

Sun W, Torrens G, Ter Beek J, Cava F, Berntsson RP

MBio 15 (8) e0048824 [2024-08-14; online 2024-06-28]

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Screening persistent organic pollutants for effects on testosterone and estrogen synthesis at human-relevant concentrations using H295R cells in 96-well plates.

Strand D, Nylander E, Höglund A, ..., Martin JW, Karlsson O

Cell Biol. Toxicol. 40 (1) 69 [2024-08-13; online 2024-08-13]

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Decrease due to pollution in the rhizosphere microbial diversity can be amended by supplementation from adapted plants of another species.

Fetsiukh A, Pall T, Timmusk S

Sci Rep 14 (1) 18806 [2024-08-13; online 2024-08-13]

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Blending Samples to Increase Accuracy and Precision of 1H NMR Urine Metabolomics.

Bay Nord A, Lindqvist H, Rådjursöga M, ..., Karlsson BG, Malmodin D

Anal. Chem. 96 (32) 13078-13085 [2024-08-13; online 2024-07-31]

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Activity of botulinum neurotoxin X and its structure when shielded by a non-toxic non-hemagglutinin protein.

Martínez-Carranza M, Škerlová J, Lee PG, ..., Dong M, Stenmark P

Commun Chem 7 (1) 179 [2024-08-13; online 2024-08-13]

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Genome Biol. 25 (1) 216 [2024-08-12; online 2024-08-12]

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Reprogramming Yarrowia lipolytica metabolism for efficient synthesis of itaconic acid from flask to semipilot scale.

Fu J, Zaghen S, Lu H, ..., Di Bartolomeo F, Kerkhoven EJ

Sci Adv 10 (32) eadn0414 [2024-08-09; online 2024-08-09]

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Multifaceted Proteome Analysis at Solubility, Redox, and Expression Dimensions for Target Identification.

Saei AA, Lundin A, Lyu H, ..., Gygi SP, Zubarev RA

Adv Sci (Weinh) - (-) e2401502 [2024-08-09; online 2024-08-09]

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Magnesium induced structural reorganization in the active site of adenylate kinase.

Nam K, Thodika ARA, Tischlik S, ..., Sauer-Eriksson AE, Wolf-Watz M

Sci Adv 10 (32) eado5504 [2024-08-09; online 2024-08-09]

Long-term ambient air pollution exposure and renal function and biomarkers of renal disease.

Kilbo Edlund K, Xu Y, Andersson EM, ..., Ljungman P, Stockfelt L

Environ Health 23 (1) 67 [2024-08-09; online 2024-08-09]

AlphaFold accelerated discovery of psychotropic agonists targeting the trace amine-associated receptor 1.

Díaz-Holguín A, Saarinen M, Vo DD, ..., Carlsson J, Svenningsson P

Sci Adv 10 (32) eadn1524 [2024-08-09; online 2024-08-07]

Micro-costing of genetic diagnostics in acute leukemia in Sweden: from standard-of-care to whole-genome sequencing.

Thangavelu T, Wirta V, Orsmark-Pietras C, ..., Rosenquist R, Levin LÅ

J Med Econ 27 (1) 1053-1060 [2024-08-08; online 2024-08-08]

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JAK inhibition decreases the autoimmune burden in Down syndrome

Rachubinski AL, Wallace E, Gurnee E, ..., Norris DA, Espinosa JM

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Genetic diversity and signatures of selection in Icelandic horses and Exmoor ponies.

Sigurðardóttir H, Ablondi M, Kristjansson T, Lindgren G, Eriksson S

BMC Genomics 25 (1) 772 [2024-08-08; online 2024-08-08]

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The genetic architecture of dog ownership: large-scale genome-wide association study in 97,552 European-ancestry individuals.

Gong T, Karlsson R, Yao S, ..., Fall T, Almqvist C

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Hypoxic-Ischemic Insult Alters Polyamine and Neurotransmitter Abundance in the Specific Neonatal Rat Brain Subregions.

Mácha H, Luptáková D, Juránek I, Andrén PE, Havlíček V

ACS Chem Neurosci 15 (15) 2811-2821 [2024-08-07; online 2024-07-26]

Applying Spatial Metabolomics To Investigate Age- and Drug-Induced Neurochemical Changes.

Vallianatou T, Angerer TB, Kaya I, ..., Svenningsson P, Andrén PE

ACS Chem Neurosci 15 (15) 2822-2829 [2024-08-07; online 2024-07-29]

Systematic review and feasibility study on pre-analytical factors and genomic analyses on archival formalin-fixed paraffin-embedded breast cancer tissue.

Salgkamis D, Sifakis EG, Agartz S, ..., Matikas A, Zerdes I

Sci Rep 14 (1) 18275 [2024-08-06; online 2024-08-06]

Few chemoreceptor genes in the ambrosia beetle Trypodendron lineatum may reflect its specialized ecology.

Biswas T, Vogel H, Biedermann PHW, ..., Yuvaraj JK, Andersson MN

BMC Genomics 25 (1) 764 [2024-08-06; online 2024-08-06]

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AssemblyQC: a Nextflow pipeline for reproducible reporting of assembly quality.

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Bioinformatics 40 (8) - [2024-08-02; online 2024-07-30]

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A genome-wide genetic screen identified targets for destabilizing the parasitophorous vacuole ofChlamydia trachomatis

Babu Sait MR, Jachmann LH, Milivojevic M, ..., Schmierer B, Sixt BS

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The novel 2024 WHO Neisseria gonorrhoeae reference strains for global quality assurance of laboratory investigations and superseded WHO N. gonorrhoeae reference strains-phenotypic, genetic and reference genome characterization.

Unemo M, Sánchez-Busó L, Golparian D, ..., Wi T, Lahra MM

J. Antimicrob. Chemother. 79 (8) 1885-1899 [2024-08-01; online 2024-06-18]

The interaction of genetics and physical activity in the pathogenesis of metabolic dysfunction associated liver disease.

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Sci Rep 14 (1) 17817 [2024-08-01; online 2024-08-01]

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Exploring the interplay between antiretroviral therapy and the gut-oral microbiome axis in people living with HIV.

Narayanan A, Kieri O, Vesterbacka J, ..., Ray S, Nowak P

Sci Rep 14 (1) 17820 [2024-08-01; online 2024-08-01]

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Ecological genomics in the Northern krill uncovers loci for local adaptation across ocean basins.

Unneberg P, Larsson M, Olsson A, ..., Meyer B, Wallberg A

Nat Commun 15 (1) 6297 [2024-08-01; online 2024-08-01]

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Why we thrive beneath a northern sky - genomic signals of selection in apple for adaptation to northern Sweden.

Skytte Af Sätra J, Garkava-Gustavsson L, Ingvarsson PK

Heredity (Edinb) 133 (2) 67-77 [2024-08-00; online 2024-06-04]

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Species-specific erosion of genetic diversity in grassland butterflies depends on landscape land cover

Nolen ZJ, Rundlöf M, Runemark A

Biological Conservation 296 (-) 110694 [2024-08-00; online 2024-08-00]

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Spatiotemporal Release of Singlet Oxygen in Low Molecular Weight Organo-Gels Upon Thermal or Photochemical External Stimuli.

Sandelin E, Schilling L, Saha E, ..., Sundén H, Wallentin CJ

Small 20 (35) e2400827 [2024-08-00; online 2024-04-25]

Soluble and hydrolyzable phenolic compounds in date fruits (Phoenix dactylifera L.) by UPLC-QTOF-MS/MS and UPLC-DAD

Alam MZ, Fristedt R, Landberg R, Kamal-Eldin A

Journal of Food Composition and Analysis 132 (-) 106354 [2024-08-00; online 2024-08-00]

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Selection against domestication alleles in introduced rabbit populations.

Andrade P, Alves JM, Pereira P, ..., Andersson L, Carneiro M

Nat Ecol Evol 8 (8) 1543-1555 [2024-08-00; online 2024-06-21]

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PrgE: an OB-fold protein from plasmid pCF10 with striking differences to prototypical bacterial SSBs.

Breidenstein A, Lamy A, Bader CP, ..., Wanrooij PH, Berntsson RP

Life Sci. Alliance 7 (8) - [2024-08-00; online 2024-05-29]

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Plasticity for the win: Flexible transcriptional response to host plant switches in the comma butterfly (Polygonia c-album).

Schneider K, Steward RA, Celorio-Mancera MP, ..., Wheat CW, Nylin S

Mol. Ecol. 33 (16) e17479 [2024-08-00; online 2024-07-22]

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One-year longitudinal changes of peripheral CD4+ T-lymphocyte counts, gut microbiome, and plaque vulnerability after an acute coronary syndrome.

I Fernández-Avila A, Gutiérrez-Ibanes E, Martín de Miguel I, ..., Correa R, Bermejo J

Int J Cardiol Heart Vasc 53 (-) 101438 [2024-08-00; online 2024-06-04]

Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer.

Bojmar L, Zambirinis CP, Hernandez JM, ..., Jarnagin WR, Lyden D

Nat. Med. 30 (8) 2170-2180 [2024-08-00; online 2024-06-28]

Migratory CD103+CD11b+ cDC2s in Peyer's patches are critical for gut IgA responses following oral immunization.

Gribonika I, Strömberg A, Chandode RK, ..., Bemark M, Lycke N

Mucosal Immunol 17 (4) 509-523 [2024-08-00; online 2024-03-15]

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Metabolic profiling of galectin-1 and galectin-3: a cross-sectional, multi-omics, association study.

Fryk E, Rodrigues Silva VR, Strindberg L, ..., Lind L, Jansson PA

Int J Obes (Lond) 48 (8) 1180-1189 [2024-08-00; online 2024-05-22]

Meat consumption and the risk of hip fracture in women and men: two prospective Swedish cohort studies.

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MOXD1 is a lineage-specific gene and a tumor suppressor in neuroblastoma

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Sci Adv 10 (25) - [2024-06-21; online 2024-06-21]

Cryo-electron microscopy reveals hydrogen positions and water networks in photosystem II.

Hussein R, Graça A, Forsman J, ..., Zouni A, Schröder WP

Science 384 (6702) 1349-1355 [2024-06-21; online 2024-06-20]

Cryo-EM [Collaborative]

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.

González-López A, Larsson DSD, Koripella RK, ..., Sanyal S, Selmer M

Sci Rep 14 (1) 14253 [2024-06-20; online 2024-06-20]

Long-range charge transfer mechanism of the III2IV2 mycobacterial supercomplex.

Riepl D, Gamiz-Hernandez AP, Kovalova T, ..., Brzezinski P, Kaila VRI

Nat Commun 15 (1) 5276 [2024-06-20; online 2024-06-20]

LAPTM4B counteracts ferroptosis via suppressing the ubiquitin-proteasome degradation of SLC7A11 in non-small cell lung cancer.

Yan R, Liu D, Guo H, ..., Blom T, Zhou K

Cell Death Dis 15 (6) 436 [2024-06-20; online 2024-06-20]

Hearing loss and its association with the proteome of perilymph, cerebrospinal fluid, and tumor tissue in patients with vestibular schwannoma.

Edvardsson Rasmussen J, Li P, Laurell G, Bergquist J, Eriksson PO

Sci Rep 14 (1) 14118 [2024-06-19; online 2024-06-19]

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Completed genome and emergence scenario of the multidrug-resistant nosocomial pathogen Staphylococcus epidermidis ST215.

Kellgren T, Dwibedi C, Widerström M, ..., Rydén P, Johansson A

BMC Microbiol. 24 (1) 215 [2024-06-19; online 2024-06-19]

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Pyrene Functionalized Norbornadiene-Quadricyclane Fluorescent Photoswitches: Characterization of their Spectral Properties and Application in Imaging of Amyloid Beta Plaques.

Ghasemi S, Shamsabadi M, Olesund A, ..., Dreos A, Moth-Poulsen K

Chemistry 30 (34) e202400322 [2024-06-17; online 2024-05-22]

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From SARS-CoV-2 to Global Preparedness: A Graphical Interface for Standardised High-Throughput Bioinformatics Analysis in Pandemic Scenarios and Surveillance of Drug Resistance.

Cumlin T, Karlsson I, Haars J, ..., Ladenvall C, Kaden R

Int J Mol Sci 25 (12) - [2024-06-17; online 2024-06-17]

Clinical Genomics Uppsala [Technology development]

Convergence and molecular evolution of floral fragrance after independent transitions to self-fertilization.

Woźniak NJ, Sartori K, Kappel C, ..., Kopka J, Sicard A

Curr. Biol. 34 (12) 2702-2711.e6 [2024-06-17; online 2024-05-21]

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Metabolomics profiling reveals the detoxification and tolerance behavior of two bread wheat (Triticum aestivum L.) varieties under arsenate stress.

Saeed M, Masood Quraishi U, Mustafa G, ..., Greger M, Naseem Malik R

Food Chem 443 (-) 138612 [2024-06-15; online 2024-01-28]

Intra-Individual Variations in How Insulin Sensitivity Responds to Long-Term Exercise: Predictions by Machine Learning Based on Large-Scale Serum Proteomics.

Viken JK, Olsen T, Drevon CA, ..., Norheim F, Lee-Ødegård S

Metabolites 14 (6) - [2024-06-15; online 2024-06-15]

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Exposing kinetic disparities between inflammasome readouts using time-resolved analysis.

Herring M, Persson A, Potter R, ..., Särndahl E, Ejdebäck M

Heliyon 10 (11) e32023 [2024-06-15; online 2024-05-29]

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Intestinal Ketogenesis and Permeability.

Casselbrant A, Elias E, Hallersund P, ..., Fändriks L, Wallenius V

Int J Mol Sci 25 (12) - [2024-06-14; online 2024-06-14]

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Comprehensive Genomic Profiling Alters Clinical Diagnoses in a Significant Fraction of Tumors Suspicious of Sarcoma.

Öfverholm I, Wallander K, Haglund C, ..., Lin Y, Haglund de Flon F

Clin. Cancer Res. 30 (12) 2647-2658 [2024-06-14; online 2024-04-04]

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Characterization of Limestone Surface Impurities and Resulting Quicklime Quality

Sandström K, Carlborg M, Eriksson M, Broström M

Minerals 14 (6) 608 [2024-06-13; online 2024-06-13]

descSPIM: an affordable and easy-to-build light-sheet microscope optimized for tissue clearing techniques.

Otomo K, Omura T, Nozawa Y, ..., Brismar H, Susaki EA

Nat Commun 15 (1) 4941 [2024-06-12; online 2024-06-12]

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Integrative transcriptomic and proteomic profiling of the effects of cell confluency on gene expression.

Lobo V, Shcherbinina E, Westholm JO, ..., Anastasakis DG, Sarshad AA

Sci Data 11 (1) 617 [2024-06-12; online 2024-06-12]

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Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice.

Masarapu Y, Cekanaviciute E, Andrusivova Z, ..., Costes SV, Giacomello S

Nat Commun 15 (1) 4778 [2024-06-11; online 2024-06-11]

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DOPA-decarboxylase is elevated in CSF, but not plasma, in prodromal and de novo Parkinson's disease.

Appleton E, Khosousi S, Ta M, ..., Iwaki H, Svenningsson P

Transl Neurodegener 13 (1) 31 [2024-06-11; online 2024-06-11]

Climate change induces shifts in coastal Baltic Sea surface water microorganism stress and photosynthesis gene expression.

Seidel L, Broman E, Ståhle M, ..., Ketzer M, Dopson M

Front Microbiol 15 (-) 1393538 [2024-06-07; online 2024-06-07]

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ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.

Zhang Y, Xie G, Lee JE, ..., Ge K, Kutateladze TG

Nat Commun 15 (1) 4883 [2024-06-07; online 2024-06-07]

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Taming Molecular Folding: Anion-Templated Foldamers with Tunable Quaternary Structures.

John EA, Riel AMS, Wieske LHE, ..., Bryantsev VS, Berryman OB

J. Am. Chem. Soc. - (-) - [2024-06-06; online 2024-06-06]

Structural diversity of Arc oligomers within the excitatory synapse

Damenti M, Coceano G, Mendes Silva M, ..., Jungmann R, Testa I

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MLL4 binds TET3.

Becht DC, Mohid SA, Lee JE, ..., Zhang Y, Kutateladze TG

Structure 32 (6) 706-714.e3 [2024-06-06; online 2024-04-04]

Long-term impact of digital media on brain development in children.

Nivins S, Sauce B, Liebherr M, Judd N, Klingberg T

Sci Rep 14 (1) 13030 [2024-06-06; online 2024-06-06]

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Effect of an endothelial regulatory module on plasma proteomics in exercising horses.

Amiri Roudbar M, Rosengren MK, Mousavi SF, ..., Meadows JRS, Lindgren G

Comp Biochem Physiol Part D Genomics Proteomics 52 (-) 101265 [2024-06-06; online 2024-06-06]

Deconwolf enables high-performance deconvolution of widefield fluorescence microscopy images.

Wernersson E, Gelali E, Girelli G, ..., Crosetto N, Bienko M

Nat. Methods - (-) - [2024-06-06; online 2024-06-06]

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Detection of rare variants among nuclei populating the arbuscular mycorrhizal fungal model species Rhizophagus irregularis DAOM197198.

Manyara D, Sánchez-García M, Montoliu-Nerin M, Rosling A

G3 (Bethesda) 14 (6) - [2024-06-05; online 2024-04-24]

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Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces.

Dear AJ, Thacker D, Wennmalm S, ..., Linse S, Knowles TPJ

ACS Chem Neurosci 15 (11) 2296-2307 [2024-06-05; online 2024-05-24]

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Structure and mechanism of the K+/H+ exchanger KefC.

Gulati A, Kokane S, Perez-Boerema A, ..., Matsuoka R, Drew D

Nat Commun 15 (1) 4751 [2024-06-04; online 2024-06-04]

Multimodal Mass Spectrometry Identifies a Conserved Protective Epitope in S. pyogenes Streptolysin O

Tang D, Gueto-Tettay C, Hjortswang E, ..., Malmström L, Malmström J

Anal. Chem. 96 (22) 9060-9068 [2024-06-04; online 2024-05-03]

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Ancient Sheep Genomes Reveal Four Millennia of North European Short-Tailed Sheep in the Baltic Sea Region.

Larsson MNA, Morell Miranda P, Pan L, ..., Storå J, Günther T

Genome Biol Evol 16 (6) - [2024-06-04; online 2024-05-25]

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A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase.

Balthazar JT, Golparian D, Unemo M, ..., Vassylyev DG, Shafer WM

Microbiol Spectr 12 (6) e0056024 [2024-06-04; online 2024-04-22]

Chemical signatures delineate heterogeneous amyloid plaque populations across the Alzheimer's disease spectrum.

Koutarapu S, Ge J, Dulewicz M, ..., Schöll M, Hanrieder J

bioRxiv - (-) - [2024-06-03; online 2024-06-03]

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A CRISPR homing screen finds a chloroquine resistance transporter-like protein of thePlasmodiumoocyst essential for mosquito transmission of malaria

Balakrishnan A, Hunziker M, Tiwary P, ..., Drew D, Billker O

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Towards identification of new genetic determinants for post-weaning diarrhea in piglets.

Ibragimov E, Eriksen EØ, Nielsen JP, ..., Fredholm M, Karlskov-Mortensen P

Anim Genet 55 (3) 387-395 [2024-06-00; online 2024-02-11]

Structure and interactions of the endogenous human Commander complex.

Laulumaa S, Kumpula EP, Huiskonen JT, Varjosalo M

Nat. Struct. Mol. Biol. 31 (6) 925-938 [2024-06-00; online 2024-03-08]

Spatial Transcriptomics in a Case of Follicular Thyroid Carcinoma Reveals Clone-Specific Dysregulation of Genes Regulating Extracellular Matrix in the Invading Front.

Condello V, Paulsson JO, Zedenius J, Näsman A, Juhlin CC

Endocr. Pathol. 35 (2) 122-133 [2024-06-00; online 2024-01-27]

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Recognising the importance and impact of Imaging Scientists: Global guidelines for establishing career paths within core facilities.

Wright GD, Thompson KA, Reis Y, ..., Vasconcelos ADS, Keppler A

J Microsc 294 (3) 397-410 [2024-06-00; online 2024-05-01]

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Proteomics of cell-free breast cancer scaffolds identify clinically relevant imprinted proteins and cancer-progressing properties.

Gustafsson A, Jonasson E, Ståhlberg A, Landberg G

Cancer Commun (Lond) 44 (6) 695-699 [2024-06-00; online 2024-04-04]

Proteomic profiling of polyglucosan bodies associated with glycogenin-1 deficiency in skeletal muscle.

Visuttijai K, Hedberg-Oldfors C, Costello DJ, Bermingham N, Oldfors A

Neuropathol Appl Neurobiol 50 (3) e12995 [2024-06-00; online 2024-06-26]

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Phylogenomic analysis of Stylops reveals the evolutionary history of a Holarctic Strepsiptera radiation parasitizing wild bees.

Lähteenaro M, Benda D, Straka J, Nylander JAA, Bergsten J

Mol. Phylogenet. Evol. 195 (-) 108068 [2024-06-00; online 2024-03-28]

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Pericyte-Specific Secretome Profiling in Hypoxia Using TurboID in a Multicellular in Vitro Spheroid Model.

Enström A, Carlsson R, Buizza C, Lewi M, Paul G

Mol. Cell Proteomics 23 (6) 100782 [2024-06-00; online 2024-05-04]

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Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support.

Amoedo-Leite C, Parv K, Testini C, ..., Christoffersson G, Phillipson M

Nat Cardiovasc Res 3 (6) 685-700 [2024-06-00; online 2024-06-06]

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Hybrid capture-based next-generation sequencing of new and old world Orthohantavirus strains and wild-type Puumala isolates from humans and bank voles.

Rosenbaum W, Bovinder Ylitalo E, Castel G, ..., Pettersson L, Tuiskunen Bäck A

J. Clin. Virol. 172 (-) 105672 [2024-06-00; online 2024-03-30]

Fine-Tuning Amyloid Precursor Protein Expression through Nonsense-Mediated mRNA Decay.

Rahmati M, Chebli J, Kumar Banote R, ..., Zetterberg H, Abramsson A

eNeuro 11 (6) - [2024-06-00; online 2024-06-10]

Expedient Bayesian prediction of subfossil bone protein content using portable ATR-FTIR data

Hixon S, Roberts P, Rodríguez-Varela R, ..., Lagia A, Fernandes R

Quaternary International 694 (-) 1-12 [2024-06-00; online 2024-06-00]

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Epigenetic dissection of human blood group genes reveals regulatory elements and detailed characteristics of KEL and four other loci.

Wu PC, McGowan EC, Lee YQ, ..., Hansson J, Olsson ML

Transfusion 64 (6) 1083-1096 [2024-06-00; online 2024-04-21]

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Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays.

Lind A, Freyhult E, de Jesus Cortez F, ..., Lernmark Å, Better Diabetes Diagnosis (BDD) study group

EBioMedicine 104 (-) 105144 [2024-06-00; online 2024-05-08]

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Cellulose gelation in aqueous hydroxide solutions by CO2(g): Fact and theory

Naserifar S, Karna NK, Kozlowski AM, Bernin D, Hasani M

Carbohydrate Polymer Technologies and Applications 7 (-) 100514 [2024-06-00; online 2024-06-00]

Blood biomarkers of Alzheimer's disease in the community: Variation by chronic diseases and inflammatory status.

Valletta M, Vetrano DL, Rizzuto D, ..., Fratiglioni L, Grande G

Alzheimers Dement 20 (6) 4115-4125 [2024-06-00; online 2024-05-08]

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Bacterial diversity in semen from stallions in three European countries evaluated by 16S sequencing.

Malaluang P, Niazi A, Guo Y, ..., Aurich C, Morrell JM

Vet Res Commun 48 (3) 1409-1421 [2024-06-00; online 2024-02-02]

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An endothelial regulatory module links blood pressure regulation with elite athletic performance.

Fegraeus K, Rosengren MK, Naboulsi R, ..., Meadows JRS, Lindgren G

PLoS Genet. 20 (6) e1011285 [2024-06-00; online 2024-06-17]

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A monoallelic UXS1 variant associated with short-limbed short stature.

Rustad CF, Backe PH, Jin C, ..., Elgstøen KBP, Holla ØL

Mol Genet Genomic Med 12 (6) e2472 [2024-06-00; online 2024-06-11]

Tumor-matched and unmatched cancer associated fibroblasts exhibit differential effect on proliferation and FMOD and MMP9 gene expression in head and neck squamous cell carcinoma cells when cocultured in spheroids.

Rademaekers M, Johansson EO, Johansson E, Roberg K, Wiechec E

Cancer Cell Int 24 (1) 190 [2024-05-31; online 2024-05-31]

Tobacco Smoke Exposure in Early Childhood and Later Risk of Inflammatory Bowel Disease: A Scandinavian Birth Cohort Study.

Sigvardsson I, Ludvigsson J, Andersson B, Størdal K, Mårild K

J Crohns Colitis 18 (5) 661-670 [2024-05-31; online 2024-02-08]

Structural conversion of the spidroin C-terminal domain during assembly of spider silk fibers.

De Oliveira DH, Gowda V, Sparrman T, ..., Lendel C, Hedhammar M

Nat Commun 15 (1) 4670 [2024-05-31; online 2024-05-31]

Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia.

Malyukova A, Lahnalampi M, Falqués-Costa T, ..., Heinäniemi M, Sangfelt O

Genome Biol. 25 (1) 143 [2024-05-31; online 2024-05-31]

PIK3CA mutations in endocrine-resistant breast cancer.

Schagerholm C, Robertson S, Toosi H, Sifakis EG, Hartman J

Sci Rep 14 (1) 12542 [2024-05-31; online 2024-05-31]

Overexpression of the plastidial pseudo-protease AtFtsHi3 enhances drought tolerance while sustaining plant growth.

Mishra LS, Cook SD, Kushwah S, ..., Libby E, Funk C

Physiol Plantarum 176 (3) e14370 [2024-05-31; online 2024-05-31]

Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids.

Boman J, Qvarnström A, Mugal CF

BMC Biol. 22 (1) 124 [2024-05-29; online 2024-05-29]

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NGS method for parallel processing of high quality, damaged or fragmented input material using target enrichment.

Lyander A, Gellerbring A, Hägglund M, Elhami K, Wirta V

PLoS ONE 19 (5) e0304411 [2024-05-29; online 2024-05-29]

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Evolutionary history of arbuscular mycorrhizal fungi and genomic signatures of obligate symbiosis.

Rosling A, Eshghi Sahraei S, Kalsoom Khan F, ..., Bonito G, Sánchez-García M

BMC Genomics 25 (1) 529 [2024-05-29; online 2024-05-29]

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The structure of the second CysD domain of MUC2 and role in mucin organization by transglutaminase-based cross-linking.

Recktenwald CV, Karlsson G, Garcia-Bonete MJ, ..., Hansson GC, Trillo-Muyo S

Cell Rep 43 (5) 114207 [2024-05-28; online 2024-05-09]

Distinct Infiltration of T Cell Populations in Bladder Cancer Molecular Subtypes.

Sincic V, Arlenhold KF, Richtmann S, ..., Liedberg F, Lundberg K

Cells 13 (11) - [2024-05-28; online 2024-05-28]

The Metabolomic Profile of Microscopic Colitis Is Affected by Smoking but Not Histopathological Diagnosis, Clinical Course, Symptoms, or Treatment.

Ström A, Stenlund H, Ohlsson B

Metabolites 14 (6) - [2024-05-27; online 2024-05-27]

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Species-specific dynamics may cause deviations from general biogeographical predictions - evidence from a population genomics study of a New Guinean endemic passerine bird family (Melampittidae).

Müller IA, Thörn F, Rajan S, ..., Jønsson KA, Irestedt M

PLoS ONE 19 (5) e0293715 [2024-05-23; online 2024-05-23]

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Quantifying combined effects of colistin and ciprofloxacin against Escherichia coli in an in silico pharmacokinetic-pharmacodynamic model.

Zhao C, Kristoffersson AN, Khan DD, ..., Nielsen EI, Friberg LE

Sci Rep 14 (1) 11706 [2024-05-22; online 2024-05-22]

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The Gly82Ser polymorphism in the receptor for advanced glycation endproducts increases the risk for coronary events in the general population.

Grauen Larsen H, Sun J, Sjögren M, ..., Melander O, Schiopu A

Sci Rep 14 (1) 11567 [2024-05-21; online 2024-05-21]

Saccharomyces cerevisiae strains performing similarly during fermentation of lignocellulosic hydrolysates show pronounced differences in transcriptional stress responses.

Cámara E, Mormino M, Siewers V, Nygård Y

Appl. Environ. Microbiol. 90 (5) e0233023 [2024-05-21; online 2024-04-08]

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Plastid phylogenomics and cytonuclear discordance in Rubioideae, Rubiaceae.

Thureborn O, Wikström N, Razafimandimbison SG, Rydin C

PLoS ONE 19 (5) e0302365 [2024-05-20; online 2024-05-20]

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MDM2 amplification in rod-shaped chromosomes provides clues to early stages of circularized gene amplification in liposarcoma.

Sydow S, Piccinelli P, Mitra S, ..., Spierings D, Mertens F

Commun Biol 7 (1) 606 [2024-05-20; online 2024-05-20]

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Defining the contribution of Troy-positive progenitor cells to the mouse esophageal epithelium.

Grommisch D, Wang M, Eenjes E, ..., Giselsson P, Genander M

Dev. Cell 59 (10) 1269-1283.e6 [2024-05-20; online 2024-04-01]

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Retron-Eco1 assembles NAD+-hydrolyzing filaments that provide immunity against bacteriophages.

Carabias A, Camara-Wilpert S, Mestre MR, ..., Pinilla-Redondo R, Montoya G

Mol. Cell - (-) - [2024-05-18; online 2024-05-18]

Prediction models of persistent taxane-induced peripheral neuropathy among breast cancer survivors using whole-exome sequencing.

Engvall K, Uvdal H, Björn N, Åvall-Lundqvist E, Gréen H

NPJ Precis Oncol 8 (1) 102 [2024-05-16; online 2024-05-16]

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Exploring carbon source related localization and phosphorylation in the Snf1/Mig1 network using population and single cell-based approaches.

Braam S, Tripodi F, Österberg L, ..., Coccetti P, Cvijovic M

Microb Cell 11 (-) 143-154 [2024-05-16; online 2024-05-16]

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Quantitation of circulating short-chain fatty acids in small volume blood samples from animals and humans.

Fristedt R, Ruppert V, Trower T, Cooney J, Landberg R

Talanta 272 (-) 125743 [2024-05-15; online 2024-02-03]

Chalmers Mass Spectrometry Infrastructure [Collaborative]

Novel findings in a Swedish primary familial brain calcification cohort.

Sennfält S, Gustavsson P, Malmgren H, ..., Svenningsson P, Paucar M

J. Neurol. Sci. 460 (-) 123020 [2024-05-15; online 2024-04-18]

Depression proteomic profiling in adolescents with transcriptome analyses in independent cohorts.

Sokolov AV, Lafta MS, Nordberg DOT, Jonsson J, Schiöth HB

Front Psychiatry 15 (-) 1372106 [2024-05-15; online 2024-05-15]

Complex genetic architecture of the chicken Growth1 QTL region.

Ou JH, Rönneburg T, Carlborg Ö, ..., Siegel PB, Rubin CJ

PLoS ONE 19 (5) e0295109 [2024-05-13; online 2024-05-13]

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Copy number variation and elevated genetic diversity at immune trait loci in Atlantic and Pacific herring.

Mohamadnejad Sangdehi F, Jamsandekar MS, Enbody ED, Pettersson ME, Andersson L

BMC Genomics 25 (1) 459 [2024-05-10; online 2024-05-10]

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Modulation of innate immune response to mRNA vaccination after SARS-CoV-2 infection or sequential vaccination in humans.

Hellgren F, Rosdahl A, Arcoverde Cerveira R, ..., Cajander S, Loré K

JCI Insight 9 (9) - [2024-05-08; online 2024-05-08]

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All-photonic kinase inhibitors: light-controlled release-and-report inhibition.

Fleming CL, Benitez-Martin C, Bernson E, ..., Grøtli M, Andréasson J

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Nat Commun 15 (1) 3837 [2024-05-07; online 2024-05-07]

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Mol Plant 17 (5) 725-746 [2024-05-06; online 2024-03-13]

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Teaching transposon classification as a means to crowd source the curation of repeat annotation - a tardigrade perspective.

Peona V, Martelossi J, Almojil D, ..., Pecoraro C, Suh A

Mob DNA 15 (1) 10 [2024-05-06; online 2024-05-06]

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Curr. Biol. 34 (9) 2020-2029.e6 [2024-05-06; online 2024-04-12]

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Chromosome Res. 32 (2) 7 [2024-05-04; online 2024-05-04]

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Genetic Causes and Genomic Consequences of Breakdown of Distyly in Linum trigynum.

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Mol. Biol. Evol. 41 (5) - [2024-05-03; online 2024-05-06]

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Hiltunen Thorén M, Onuț-Brännström I, Alfjorden A, ..., Bass D, Burki F

BMC Biol. 22 (1) 103 [2024-05-03; online 2024-05-03]

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Recent dynamics in Neisseria gonorrhoeae genomic epidemiology in Brazil: antimicrobial resistance and genomic lineages in 2017-20 compared to 2015-16.

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J. Antimicrob. Chemother. 79 (5) 1081-1092 [2024-05-02; online 2024-03-22]

Pharmacodynamic evaluation of ceftriaxone single-dose therapy (0.125-1 g) to eradicate ceftriaxone-susceptible and ceftriaxone-resistant Neisseria gonorrhoeae strains in a hollow fibre infection model for gonorrhoea.

Unemo M, Golparian D, Oxelbark J, ..., Drusano G, Jacobsson S

J. Antimicrob. Chemother. 79 (5) 1006-1013 [2024-05-02; online 2024-03-18]

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Castro Dopico X, Guryleva M, Mandolesi M, ..., Murrell B, Karlsson Hedestam GB

Clin Transl Immunology 13 (5) e1508 [2024-05-02; online 2024-05-02]

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Growth and mortality rates of picophytoplankton in the Baltic Sea Proper

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Mar. Ecol. Prog. Ser. 735 (-) 63-76 [2024-05-02; online 2024-05-02]

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Genomic alterations in ovarian endometriosis and subsequently diagnosed ovarian carcinoma.

Linder A, Westbom-Fremer S, Mateoiu C, ..., Hedenfalk I, Sundfeldt K

Hum. Reprod. 39 (5) 1141-1154 [2024-05-02; online 2024-03-09]

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Experimental Evaluation of a Direct Fitness Effect of the De Novo Evolved Mouse Gene Pldi.

Linnenbrink M, Breton G, Misra P, ..., Dutheil JY, Tautz D

Genome Biol Evol 16 (5) - [2024-05-02; online 2024-05-14]

Evolutionary convergence of sensory circuits in the pallium of amniotes

Rueda-Alaña E, Senovilla-Ganzo R, Grillo M, ..., De Pitta M, García-Moreno F

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Sex-biased gene expression during neural differentiation of human embryonic stem cells

Pottmeier P, Nikolantonaki D, Lanner F, Peuckert C, Jazin E

Front Cell Dev Biol 12 (-) - [2024-05-01; online 2024-05-01]

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Panara V, Yu H, Peng D, ..., Hogan BM, Koltowska K

Development 151 (9) - [2024-05-01; online 2024-05-09]

Male-transmitted transgenerational effects of the herbicide linuron on DNA methylation profiles in Xenopus tropicalis brain and testis.

Roza M, Eriksson ANM, Svanholm S, Berg C, Karlsson O

Sci. Total Environ. 923 (-) 170949 [2024-05-01; online 2024-02-15]

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Chromatin accessibility during human first-trimester neurodevelopment.

Mannens CCA, Hu L, Lönnerberg P, ..., Posthuma D, Linnarsson S

Nature - (-) - [2024-05-01; online 2024-05-01]

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Unlocking the secret life of blue mussels: Exploring connectivity in the Skagerrak through biophysical modeling and population genomics.

Gustafsson M, Strand Å, Laugen AT, ..., Wrange AL, De Wit P

Evol Appl 17 (5) e13704 [2024-05-00; online 2024-05-20]

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Ruxolitinib: A new hope for ventilator-induced diaphragm dysfunction.

Addinsall AB, Cacciani N, Moruzzi N, ..., Kirkland JL, Larsson L

Acta Physiol (Oxf) 240 (5) e14128 [2024-05-00; online 2024-03-29]

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Plasma proteomics for prediction of subclinical coronary artery calcifications in primary prevention.

Royer P, Björnson E, Adiels M, ..., Gummesson A, Bergström G

Am. Heart J. 271 (-) 55-67 [2024-05-00; online 2024-02-05]

Novel Associations Between Mid-Pregnancy Cardiovascular Biomarkers and Preeclampsia: An Explorative Nested Case-Control Study.

Callbo PN, Junus K, Gabrysch K, ..., Lager S, Wikström AK

Reprod Sci 31 (5) 1391-1400 [2024-05-00; online 2024-01-22]

Low birthweight and overweight during childhood and young adulthood and the risk of type 2 diabetes in men: a population-based cohort study.

Célind J, Bygdell M, Bramsved R, ..., Ohlsson C, Kindblom JM

Diabetologia 67 (5) 874-884 [2024-05-00; online 2024-02-22]

Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea.

Wellhagen GJ, Karlsson MO, Kjellsson MC, ..., Weimann G, Yassen A

CPT Pharmacometrics Syst Pharmacol 13 (5) 880-890 [2024-05-00; online 2024-03-12]

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In situ seasonal patterns of root auxin concentrations and meristem length in an arctic sedge.

Blume-Werry G, Semenchuk P, Ljung K, ..., Olofsson J, Brunoni F

New Phytol. 242 (3) 988-999 [2024-05-00; online 2024-02-20]

Impact of the neurotoxin β-N-methylamino-L-alanine on the diatom Thalassiosira pseudonana using metabolomics.

Kim SY, Rasmussen U, Rydberg S

Mar Pollut Bull 202 (-) 116299 [2024-05-00; online 2024-04-06]

Head-to-head comparison of relevant cell sources of small extracellular vesicles for cardiac repair: Superiority of embryonic stem cells.

González-King H, Rodrigues PG, Albery T, ..., Wang QD, Jennbacken K

J Extracell Vesicles 13 (5) e12445 [2024-05-00; online 2024-05-07]

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Fluorescently labeled prey surrogates in combination with fluorescence‐activated cell sorting successfully discriminate actively feeding mixotrophs in a lake water sample

Florenza J, Divne A, Bertilsson S

Limnol Oceanogr 69 (5) 1030-1044 [2024-05-00; online 2024-03-13]

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Fasting plasma metabolites reflecting meat consumption and their associations with incident type 2 diabetes in two Swedish cohorts.

Noerman S, Johansson A, Shi L, ..., Brunius C, Landberg R

Am. J. Clin. Nutr. 119 (5) 1280-1292 [2024-05-00; online 2024-02-23]

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Evaluation of covariate effects in item response theory models.

Wellhagen GJ, Yassen A, Garmann D, ..., Kjellsson MC, Karlsson MO

CPT Pharmacometrics Syst Pharmacol 13 (5) 812-822 [2024-05-00; online 2024-03-04]

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Ectomycorrhizal fungi are more sensitive to high soil nitrogen levels in forests exposed to nitrogen deposition.

Jörgensen K, Clemmensen KE, Wallander H, Lindahl BD

New Phytol. 242 (4) 1725-1738 [2024-05-00; online 2024-01-11]

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Comparison and optimization of protocols and whole-genome capture conditions for ancient DNA samples.

Yaka R, Lagerholm VK, Linderholm A, ..., Somel M, Götherström A

BioTechniques 76 (5) 216-223 [2024-05-00; online 2024-03-26]

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Antimicrobial-resistant Neisseria gonorrhoeae in Europe in 2020 compared with in 2013 and 2018: a retrospective genomic surveillance study.

Golparian D, Cole MJ, Sánchez-Busó L, ..., Unemo M, Euro-GASP study group

Lancet Microbe 5 (5) e478-e488 [2024-05-00; online 2024-04-10]

Metabolomics for early pancreatic cancer detection in plasma samples from a Swedish prospective population-based biobank.

Borgmästars E, Jacobson S, Simm M, ..., Franklin O, Sund M

J Gastrointest Oncol 15 (2) 755-767 [2024-04-30; online 2024-04-28]

PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.

Filograna R, Gerlach J, Choi H, ..., Svenningsson P, Larsson N

NPJ Parkinsons Dis 10 (1) 93 [2024-04-29; online 2024-04-29]

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Local Immune Activation and Age Impact on Humoral Immunity in Mice, with a Focus on IgG Sialylation.

Gupta P, Sághy T, Bollmann M, ..., Corciulo C, Engdahl C

Vaccines (Basel) 12 (5) - [2024-04-29; online 2024-04-29]

Biomarker Candidates of Habitual Food Intake in a Swedish Cohort of Pregnant and Lactating Women and Their Infants.

Stråvik M, Hartvigsson O, Noerman S, ..., Barman M, Sandberg AS

Metabolites 14 (5) - [2024-04-29; online 2024-04-29]

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The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies.

Izadi A, Karami Y, Bratanis E, ..., Malmström L, Nordenfelt P

Nat Commun 15 (1) 3600 [2024-04-27; online 2024-04-27]

Population genomic history of the endangered Anatolian and Cyprian mouflons in relation to worldwide wild, feral and domestic sheep lineages.

Atağ G, Kaptan D, Yüncü E, ..., Hadjisterkotis E, Somel M

Genome Biol Evol - (-) - [2024-04-27; online 2024-04-27]

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Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer.

Papakyriacou I, Kutkaite G, Rúbies Bedós M, ..., Menden MP, Mao Y

Nat Commun 15 (1) 3581 [2024-04-27; online 2024-04-27]

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Cyanotoxin Occurrence and Diversity in 98 Cyanobacterial Blooms from Swedish Lakes and the Baltic Sea.

Dirks C, Cappelli P, Blomqvist M, ..., Pekar H, Zuberovic Muratovic A

Mar Drugs 22 (5) - [2024-04-27; online 2024-04-27]

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Phenotypic characterization and candidate gene analysis of a short kernel and brassinosteroid insensitive mutant from hexaploid oat (Avena sativa).

Tsardakas Renhuldt N, Bentzer J, Ahrén D, Marmon S, Sirijovski N

Front Plant Sci 15 (-) 1358490 [2024-04-26; online 2024-04-26]

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Deciphering the role of FUS::DDIT3 expression and tumor microenvironment in myxoid liposarcoma development.

Ranji P, Jonasson E, Andersson L, ..., Åman P, Ståhlberg A

J Transl Med 22 (1) 389 [2024-04-26; online 2024-04-26]

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The gut commensal Blautia maintains colonic mucus function under low-fiber consumption through secretion of short-chain fatty acids.

Holmberg SM, Feeney RH, Prasoodanan P K V, ..., Skurk T, Schroeder BO

Nat Commun 15 (1) 3502 [2024-04-25; online 2024-04-25]

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N-glycoproteomic analyses of human intestinal enteroids, varying in histo-blood group geno- and phenotypes, reveal a wide repertoire of fucosylated glycoproteins.

Nilsson J, Rimkute I, Sihlbom C, ..., Estes MK, Larson G

Glycobiology 34 (6) - [2024-04-24; online 2024-04-09]

High clonal diversity and spatial genetic admixture in early prostate cancer and surrounding normal tissue.

Zhang N, Harbers L, Simonetti M, ..., Bienko M, Crosetto N

Nat Commun 15 (1) 3475 [2024-04-24; online 2024-04-24]

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Exhaustive identification of genome-wide binding events of transcriptional regulators.

Nordin A, Pagella P, Zambanini G, Cantù C

Nucleic Acids Res. 52 (7) e40 [2024-04-24; online 2024-03-19]

Very short sleep duration reveals a proteomic fingerprint that is selectively associated with incident diabetes mellitus but not with incident coronary heart disease: a cohort study.

Svensson T, Svensson AK, Kitlinski M, ..., Nilsson PM, Melander O

BMC Med 22 (1) 173 [2024-04-23; online 2024-04-23]

Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor.

Engström Ruud L, Font-Gironès F, Zajdel J, ..., Bäckhed F, Ruud J

Cell Rep 43 (4) 113960 [2024-04-23; online 2024-03-19]

A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation.

Knyazeva A, Li S, Corkery DP, ..., Waldmann H, Wu YW

Proc. Natl. Acad. Sci. U.S.A. 121 (17) e2317680121 [2024-04-23; online 2024-04-18]

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Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.

Altay O, Yang H, Yildirim S, ..., Turkez H, Mardinoglu A

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TMAO enhances TNF-α mediated fibrosis and release of inflammatory mediators from renal fibroblasts.

Stefania K, Ashok KK, Geena PV, Katarina P, Isak D

Sci Rep 14 (1) 9070 [2024-04-20; online 2024-04-20]

Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation.

Tobiasson M, Pandzic T, Illman J, ..., Dybedal I, Hellström-Lindberg E

J Clin Oncol 42 (12) 1378-1390 [2024-04-20; online 2024-01-17]

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HIV-2 mediated effects on target and bystander cells induce plasma proteome remodeling.

Johansson E, Nazziwa J, Freyhult E, ..., Jansson M, SWEGUB CORE group

iScience 27 (4) 109344 [2024-04-19; online 2024-02-28]

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Radiolabeled 15-mer peptide internalization is mediated by megalin (LRP2 receptor) in a CRISPR/Cas9-based LRP2 knockout human kidney cell model.

Durinova A, Smutna L, Barta P, ..., Pavek P, Trejtnar F

EJNMMI Radiopharm Chem 9 (1) 32 [2024-04-18; online 2024-04-18]

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Long-read sequencing and optical mapping generates near T2T assemblies that resolves a centromeric translocation.

Ten Berk de Boer E, Ameur A, Bunikis I, ..., Eisfeldt J, Lindstrand A

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Nutrient-deprived growth of streptomycetes reveals a novel growth phenotype with enhanced antimicrobial activity

Söderholm N, Tanner H, Sandblad L

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Effects of bottom trawling and environmental factors on benthic bacteria, meiofauna and macrofauna communities and benthic ecosystem processes.

Bradshaw C, Iburg S, Morys C, ..., Jonsson P, Nascimento FJA

Sci. Total Environ. 921 (-) 171076 [2024-04-15; online 2024-02-19]

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Amperometry and Electron Microscopy show Stress Granules Induce Homotypic Fusion of Catecholamine Vesicles.

Gu H, Gu C, Locker N, Ewing AG

Angew. Chem. Int. Ed. Engl. 63 (16) e202400422 [2024-04-15; online 2024-03-07]

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Growth-regulated co-occupancy of Mediator and Lsm3 at intronic ribosomal protein genes.

Abdel-Fattah WR, Carlsson M, Hu G, ..., Ronne H, Björklund S

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Evolution of microRNAs in Amoebozoa and implications for the origin of multicellularity.

Edelbroek B, Kjellin J, Biryukova I, ..., Friedländer MR, Söderbom F

Nucleic Acids Res. 52 (6) 3121-3136 [2024-04-12; online 2024-02-20]

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Dual molecule targeting HDAC6 leads to intratumoral CD4+ cytotoxic lymphocytes recruitment through MHC-II upregulation on lung cancer cells.

Ducellier S, Demeules M, Letribot B, ..., Nascimento M, Apcher S

J Immunother Cancer 12 (4) - [2024-04-11; online 2024-04-11]

Cellular architecture of evolving neuroinflammatory lesions and multiple sclerosis pathology.

Kukanja P, Langseth CM, Rubio Rodríguez-Kirby LA, ..., Nilsson M, Castelo-Branco G

Cell 187 (8) 1990-2009.e19 [2024-04-11; online 2024-03-20]

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A time course analysis through diapause reveals dynamic temporal patterns of microRNAs associated with endocrine regulation in the butterfly Pieris napi.

Roberts KT, Steward RA, Süess P, Lehmann P, Wheat CW

Mol. Ecol. - (-) e17348 [2024-04-10; online 2024-04-10]

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Molecular patterns of resistance to immune checkpoint blockade in melanoma.

Lauss M, Phung B, Borch TH, ..., Donia M, Jönsson G

Nat Commun 15 (1) 3075 [2024-04-09; online 2024-04-09]

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Exploring the short linear motif-mediated protein-protein interactions of CrkL through ProP-PD.

Pagano L, Simonetti L, Pennacchietti V, ..., Ivarsson Y, Gianni S

Biochem. Biophys. Res. Commun. 703 (-) 149658 [2024-04-09; online 2024-02-07]

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Deletion of the TMEM30A gene enables leukemic cell evasion of NK cell cytotoxicity.

Kristenson L, Badami C, Ljungberg A, ..., Tang KW, Thorén FB

Proc. Natl. Acad. Sci. U.S.A. 121 (15) e2316447121 [2024-04-09; online 2024-04-01]

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Antibiotic class with potent in vivo activity targeting lipopolysaccharide synthesis in Gram-negative bacteria.

Huseby DL, Cao S, Zamaratski E, ..., Hughes D, Karlén A

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A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells.

Fonseca P, Cui W, Struyf N, ..., Östling P, Holmgren L

J. Exp. Clin. Cancer Res. 43 (1) 107 [2024-04-09; online 2024-04-09]

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Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model.

Yaghmaeian Salmani B, Lahti L, Gillberg L, ..., Svenningsson P, Perlmann T

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Histones are exosome membrane proteins regulated by cell stress

Singh B, Sundbom MF, Muthukrishnan U, ..., Haney M, Gilthorpe JD

- - (-) - [2024-04-08; online 2024-04-08]

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Tissue-specific nonheritable influences drive endometrial immune system variation.

Bister J, Filipovic I, Sun D, ..., Strunz B, Björkström NK

Sci Immunol 9 (94) eadj7168 [2024-04-05; online 2024-04-05]

Functional redundancy revealed by the deletion of the mimivirus GMC-oxidoreductase genes.

Alempic JM, Bisio H, Villalta A, ..., Couté Y, Abergel C

Microlife 5 (-) uqae006 [2024-04-05; online 2024-04-05]

Adaptive introgression reveals the genetic basis of a sexually selected syndrome in wall lizards.

Feiner N, Yang W, Bunikis I, While GM, Uller T

Sci Adv 10 (14) eadk9315 [2024-04-05; online 2024-04-03]

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Treatment Monitoring of a Patient with Synchronous Metastatic Angiosarcoma and Breast Cancer Using ctDNA.

Vannas C, Escobar M, Österlund T, ..., Fagman H, Ståhlberg A

Int J Mol Sci 25 (7) - [2024-04-04; online 2024-04-04]

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The HLA region in ANCA-associated vasculitis: characterisation of genetic associations in a Scandinavian patient population.

Lundtoft C, Knight A, Meadows JRS, ..., Lindblad-Toh K, Dahlqvist J

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Regulation of ADP-ribosyltransferase activity by ART domain dimerization in PARP15

Ebenwaldner C, García Saura AG, Ekström S, Bernfur K, Schüler H

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Extracellular vesicles isolated from frozen and fresh human melanoma tissue are similar in purity and protein composition

D’Arrigo D, Lässer C, Urzì O, ..., Lötvall J, Crescitelli R

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Adjusting for covariates and assessing modeling fitness in machine learning using MUVR2.

Yan Y, Schillemans T, Skantze V, Brunius C

Bioinform Adv 4 (1) vbae051 [2024-04-04; online 2024-04-04]

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Proteome profiling of home-sampled dried blood spots reveals proteins of SARS-CoV-2 infections.

Fredolini C, Dodig-Crnković T, Bendes A, ..., Roxhed N, Schwenk JM

Commun Med (Lond) 4 (1) 55 [2024-04-02; online 2024-04-02]

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Larsson S, Holmgren S, Jenndahl L, ..., Synnergren J, Ghosheh N

ACS Omega 9 (13) 14805-14817 [2024-04-02; online 2024-03-19]

Ligand-induced protein transition state stabilization switches the binding pathway from conformational selection to induced fit.

Stenström O, Diehl C, Modig K, Akke M

Proc. Natl. Acad. Sci. U.S.A. 121 (14) e2317747121 [2024-04-02; online 2024-03-25]

Chromosome-scale Genome Assembly of the Rough Periwinkle Littorina saxatilis.

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Increased matrix stiffness enhances pro-tumorigenic traits in a physiologically relevant breast tissue- monocyte 3D model.

Abrahamsson A, Boroojeni FR, Naeimipour S, ..., Aili D, Dabrosin C

Acta Biomater 178 (-) 160-169 [2024-04-01; online 2024-02-20]

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Biomed. Opt. Express 15 (4) 2281 [2024-04-01; online 2024-03-11]

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Expression of influenza A virus glycan receptor candidates in mallard, chicken, and tufted duck.

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Novel ultrasensitive immunoassay for the selective quantification of tau oligomers and related soluble aggregates.

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Meta-analysis of ACE inhibitor-induced angioedema identifies novel risk locus.

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Liprin-α proteins are master regulators of human presynapse assembly.

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Materials Today Energy 41 (-) 101524 [2024-04-00; online 2024-04-00]

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A step towards more eco-friendly and efficient microalgal harvesting: Inducing flocculation in the non-naturally flocculating strain Chlorella vulgaris (13-1) without chemical additives

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Clin Epigenetics 16 (1) 49 [2024-03-28; online 2024-03-28]

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Cell Commun Signal 22 (1) 198 [2024-03-28; online 2024-03-28]

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Effects of microgravity on neural crest stem cells.

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Front. Neurosci. 18 (-) 1379076 [2024-03-27; online 2024-03-27]

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Front Microbiol 15 (-) 1369102 [2024-03-26; online 2024-03-26]

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Novel Synonymous and Deep Intronic Variants Causing Primary and Secondary Pyruvate Dehydrogenase Complex Deficiency

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Ion mobility-tandem mass spectrometry of mucin-type O-glycans.

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Nat Commun 15 (1) 2611 [2024-03-23; online 2024-03-23]

Vascular smooth muscle cells in response to cholesterol crystals modulates inflammatory cytokines release and promotes neutrophil extracellular trap formation.

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Mol. Med. 30 (1) 42 [2024-03-22; online 2024-03-22]

Abstract 2025: Zeb1 downregulation sensitizes pancreatic cancer-associated fibroblasts to killing by oncolytic reovirus through upregulation of the reovirus receptor junction adhesion molecule A

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METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma.

Vaid R, Thombare K, Mendez A, ..., Fischer M, Mondal T

Nucleic Acids Res. 52 (5) 2648-2671 [2024-03-21; online 2024-01-05]

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Modelling age at death reveals Nordic Corded Ware paleodemography

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Nat Commun 15 (1) 2358 [2024-03-20; online 2024-03-20]

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MicroRNA-155 mediates multiple gene regulations pertinent to the role of human adipose-derived mesenchymal stem cells in skin regeneration.

Shahin H, Belcastro L, Das J, ..., Elmasry M, El-Serafi AT

Front Bioeng Biotechnol 12 (-) 1328504 [2024-03-18; online 2024-03-18]

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Plant Methods 20 (1) 41 [2024-03-16; online 2024-03-16]

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Front Cardiovasc Med 11 (-) 1376367 [2024-03-15; online 2024-03-15]

Influence of divalent cations on the extraction of organic acids in coffee determined by GC-MS and NMR.

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Folded Alpha Helical Putative New Proteins from Apilactobacillus kunkeei.

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J. Mol. Biol. 436 (6) 168490 [2024-03-15; online 2024-02-13]

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Comparison of SARS-CoV-2 spike-specific IgA and IgG in nasal secretions, saliva and serum.

Bladh O, Aguilera K, Marking U, ..., Thålin C, Åberg M

Front Immunol 15 (-) 1346749 [2024-03-15; online 2024-03-15]

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Biochemical analysis of the endoribonuclease activity of the human mitochondrial topoisomerase 1

Bader CPJ, Kasho E, Forslund JME, Wessels M, Wanrooij PH

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A distinctive tumor compartment in pancreatic lobules defined by nascent stroma and classical tumor cell phenotype

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Integrated preservation of water activity as key to intensified chemoenzymatic synthesis of bio-based styrene derivatives.

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Commun Chem 7 (1) 57 [2024-03-14; online 2024-03-14]

Identification and surveillance of rare relapse-initiating stem cells during complete remission after transplantation.

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Blood 143 (11) 953-966 [2024-03-14; online 2023-12-14]

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Characterization of intestinal O-glycome in reactive oxygen species deficiency.

Saldova R, Thomsson KA, Wilkinson H, ..., Karlsson NG, Knaus UG

PLoS ONE 19 (3) e0297292 [2024-03-14; online 2024-03-14]

Cell-Mediated Proteomics, and Serological and Mucosal Humoral Immune Responses after Seasonal Influenza Immunization: Characterization of Serological Responders and Non-Responders.

Carlsson H, Brudin L, Serrander L, Hinkula J, Tjernberg I

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Transcriptomic and proteomic profiles of fetal versus adult mesenchymal stromal cells and mesenchymal stromal cell-derived extracellular vesicles.

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Complete reference genomes of two ceftriaxone-resistant Neisseria gonorrhoeae strains identified in routine surveillance in Bangkok, Thailand, using Nanopore Q20+ chemistry, VolTRAX V2b, and Illumina sequencing.

Sangprasert P, Golparian D, Paopang P, ..., Kittiyaowanarn R, Unemo M

Microbiol Resour Announc 13 (3) e0123123 [2024-03-12; online 2024-02-01]

Biofilm colonization and succession in a full-scale partial nitritation-anammox moving bed biofilm reactor.

Suarez C, Rosenqvist T, Dimitrova I, ..., Hermansson M, Persson F

Microbiome 12 (1) 51 [2024-03-12; online 2024-03-12]

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Cardiac biopsies reveal differences in transcriptomics between left and right ventricle in patients with or without diagnostic signs of heart failure.

Frisk C, Das S, Eriksson MJ, ..., Linde C, Persson B

Sci Rep 14 (1) 5811 [2024-03-09; online 2024-03-09]

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Nuclear RNAi Modulates Influenza A Virus Infectivity By Downregulating Type-I Interferon Response

Huang HC, Nowak I, Lobo V, ..., Angeletti D, Sarshad AA

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Identification of microbial pathogens in Neolithic Scandinavian humans.

Bergfeldt N, Kırdök E, Oskolkov N, ..., Storå J, Götherström A

Sci Rep 14 (1) 5630 [2024-03-07; online 2024-03-07]

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Early-life diet and risk of inflammatory bowel disease: a pooled study in two Scandinavian birth cohorts.

Guo A, Ludvigsson J, Brantsæter AL, ..., Størdal K, Mårild K

Gut 73 (4) 590-600 [2024-03-07; online 2024-03-07]

AutonoMS: Automated Ion Mobility Metabolomic Fingerprinting.

Reder GK, Bjurström EY, Brunnsåker D, ..., McLean JA, King RD

J. Am. Soc. Mass Spectrom. 35 (3) 542-550 [2024-03-06; online 2024-02-04]

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The serological immunogenicity of the third and fourth doses of COVID-19 vaccine in patients with inflammatory rheumatic diseases on different biologic or targeted DMARDs: a Swedish nationwide study (COVID-19-REUMA).

Frodlund M, Nived P, Chatzidionysiou K, ..., Klareskog L, Kapetanovic M

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BMC Genomics 25 (1) 243 [2024-03-05; online 2024-03-05]

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Genomic ancestry and social dynamics of the last hunter-gatherers of Atlantic France.

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Proc. Natl. Acad. Sci. U.S.A. 121 (10) e2310545121 [2024-03-05; online 2024-02-26]

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Biohybrid Energy Storage Circuits Based on Electronically Functionalized Plant Roots.

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ACS Appl Mater Interfaces - (-) - [2024-03-05; online 2024-03-05]

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fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles.

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Nat Commun 15 (1) 1950 [2024-03-02; online 2024-03-02]

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Towards objective measurements of habitual dietary intake patterns: comparing NMR metabolomics and food frequency questionnaire data in a population-based cohort.

Winkvist A, Johansson I, Ellegård L, Lindqvist HM

Nutr J 23 (1) 29 [2024-03-02; online 2024-03-02]

High-Quality Genome Assemblies of 4 Members of the Podospora anserina Species Complex.

Ament-Velásquez SL, Vogan AA, Wallerman O, ..., Giraud T, Johannesson H

Genome Biol Evol 16 (3) - [2024-03-02; online 2024-02-22]

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Multimodal bioimaging across disciplines and scales: challenges, opportunities and breaking down barriers

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Eur J Pharm Sci 194 (-) 106702 [2024-03-01; online 2024-01-12]

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Aberrant MNX1 expression associated with t(7;12)(q36;p13) pediatric acute myeloid leukemia induces the disease through altering histone methylation.

Waraky A, Östlund A, Nilsson T, ..., Plass C, Palmqvist L

Haematologica 109 (3) 725-739 [2024-03-01; online 2024-03-01]

The regulation of methylation on the Z chromosome and the identification of multiple novel Male Hyper-Methylated regions in the chicken.

Höglund A, Henriksen R, Churcher AM, ..., Jensen P, Wright D

PLoS Genet. 20 (3) e1010719 [2024-03-00; online 2024-03-08]

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The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk.

Grassmann F, Mälarstig A, Dahl L, ..., Schwenk JM, Czene K

Br. J. Cancer 130 (4) 620-627 [2024-03-00; online 2023-12-22]

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The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.

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Nat. Immunol. 25 (3) 432-447 [2024-03-00; online 2024-02-26]

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Temporal stability of fecal metabolomic profiles in irritable bowel syndrome.

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Neurogastroenterol. Motil. 36 (3) e14741 [2024-03-00; online 2024-01-19]

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EMBO Rep. 25 (3) 1022-1054 [2024-03-00; online 2024-02-08]

Subcutaneous Marzeptacog Alfa (Activated) for On-Demand Treatment of Bleeding Events in Subjects With Hemophilia A or B With Inhibitors.

Faraj A, Nyberg J, Blouse GE, Knudsen T, Simonsson USH

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Sorption of pharmaceuticals to foam and aerobic granular sludge with different morphologies

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Resources, Environment and Sustainability 15 (-) 100149 [2024-03-00; online 2024-03-00]

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Rare coding variants in NOX4 link high ROS levels to psoriatic arthritis mutilans.

Wang S, Nikamo P, Laasonen L, ..., Ståhle M, Tapia-Paez I

EMBO Mol Med 16 (3) 596-615 [2024-03-00; online 2024-02-20]

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Prevalence of SARS-CoV-2 infections among Swedish healthcare workers on duty in December 2023.

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Lancet Reg Health Eur 38 (-) 100872 [2024-03-00; online 2024-02-08]

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Maintenance of Behavioral Variation under Predation Risk: Effects on Personality, Plasticity, and Predictability.

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Am Nat 203 (3) 347-361 [2024-03-00; online 2024-01-23]

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Machine learning predicts system-wide metabolic flux control in cyanobacteria.

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Kupffer cells dictate hepatic responses to the atherogenic dyslipidemic insult.

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EBioMedicine 101 (-) 105001 [2024-03-00; online 2024-02-15]

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Eur. J. Hum. Genet. 32 (3) 333-341 [2024-03-00; online 2023-06-05]

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Heredity (Edinb) 132 (3) 142-155 [2024-03-00; online 2024-01-30]

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Comparison of high-throughput single-cell RNA-seq methods for ex vivo drug screening.

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Associations between inflammatory and angiogenic proteomic biomarkers, and cardiovascular events and mortality in relation to kidney function.

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Evol Appl 17 (3) e13675 [2024-03-00; online 2024-03-14]

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PLoS ONE 19 (2) e0299075 [2024-02-29; online 2024-02-29]

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Population genomic analyses reveal that salinity and geographic isolation drive diversification in a free-living protist.

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Sci Rep 14 (1) 4986 [2024-02-29; online 2024-02-29]

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BMC Plant Biol. 24 (1) 144 [2024-02-28; online 2024-02-28]

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Chem. Sci. 15 (9) 3311-3322 [2024-02-28; online 2024-01-29]

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Tumor Predisposing Post-Zygotic Chromosomal Alterations in Bladder Cancer-Insights from Histologically Normal Urothelium.

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Nat Commun 15 (1) 1752 [2024-02-26; online 2024-02-26]

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Spatial Neurolipidomics at the Single Amyloid-β Plaque Level in Postmortem Human Alzheimer's Disease Brain.

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Sci Rep 14 (1) 4210 [2024-02-20; online 2024-02-20]

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Ancient reindeer mitogenomes reveal island-hopping colonisation of the Arctic archipelagos.

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Sci Rep 14 (1) 4143 [2024-02-20; online 2024-02-20]

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MicroRNAs as Plasma Biomarkers of Hepatocellular Carcinoma in Patients with Liver Cirrhosis-A Cross-Sectional Study.

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Bhardwaj A, Münch A, Montague J, ..., Rosenstiel P, Escudero-Hernández C

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Targeting the Main Protease (Mpro, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based Methodologies.

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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel.

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iScience 27 (2) 108907 [2024-02-16; online 2024-01-13]

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Warsi OM, Upterworth LM, Breidenstein A, ..., Ingmer H, Andersson DI

MBio 15 (2) e0315523 [2024-02-14; online 2024-01-12]

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Sci Rep 14 (1) 3668 [2024-02-14; online 2024-02-14]

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Huang P, Åbacka H, Wilson CJ, ..., Venskutonytė R, Lindkvist-Petersson K

Proc. Natl. Acad. Sci. U.S.A. 121 (7) e2319682121 [2024-02-13; online 2024-02-06]

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Exploration of differential responses to FODMAPs and gluten in people with irritable bowel syndrome- a double-blind randomized cross-over challenge study.

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Front Immunol 14 (-) 1330153 [2024-02-09; online 2024-02-09]

Exploring the Dispersion and Electrostatic Components in Arene-Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands.

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Nat Commun 15 (1) 1150 [2024-02-07; online 2024-02-07]

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Front Plant Sci 15 (-) 1284997 [2024-02-06; online 2024-02-06]

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Editorial: Decoding the genome of acute lymphoblastic leukemia through genomic and transcriptomic approaches.

Jiménez-Morales S, Rojas-Martinez A, Barbany G

Front Oncol 14 (-) 1368676 [2024-02-06; online 2024-02-06]

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Proc. Natl. Acad. Sci. U.S.A. 121 (6) e2313185121 [2024-02-06; online 2024-02-01]

Nigral transcriptomic profiles in Engrailed-1 hemizygous mouse models of Parkinson's disease reveal upregulation of oxidative phosphorylation-related genes associated with delayed dopaminergic neurodegeneration.

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Front Aging Neurosci 16 (-) 1337365 [2024-02-05; online 2024-02-05]

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Eur J Med Chem 265 (-) 116122 [2024-02-05; online 2024-01-03]

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BMC Ecol Evol 24 (1) 19 [2024-02-03; online 2024-02-03]

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Exploring TRF2-Dependent DNA Distortion Through Single-DNA Manipulation Studies.

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Cell 187 (3) 733-749.e16 [2024-02-01; online 2024-02-03]

Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia.

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Haematologica 109 (2) 646-651 [2024-02-01; online 2024-02-01]

Reagentless impedimetric immunosensor for monitoring of methotrexate in human blood serum using multiwalled carbon nanotube@polypyrrole/polytyramine film electrode.

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Kahsay A, Dennhag N, Liu JX, ..., von Hofsten J, Pedrosa Domellöf F

Invest Ophthalmol Vis Sci 65 (2) 19 [2024-02-01; online 2024-02-09]

A Chromosome-Level Genome Assembly and Annotation for the Clouded Apollo Butterfly (Parnassius mnemosyne): A Species of Global Conservation Concern.

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Genome Biol Evol 16 (2) - [2024-02-01; online 2024-02-18]

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Whole exome sequencing and polygenic assessment of a Swedish cohort with severe developmental language disorder

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Vaginal candida infection is associated with host molecular signatures of neutrophil activation in the adjacent ectocervical mucosa in Kenyan sex workers

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American J Rep Immunol 91 (2) - [2024-02-00; online 2024-01-31]

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Ultrastructural insights into the microsporidian infection apparatus reveal the kinetics and morphological transitions of polar tube and cargo during host cell invasion.

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PLoS Biol. 22 (2) e3002533 [2024-02-00; online 2024-02-29]

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The cryo-EM structure of the BoNT/Wo-NTNH complex reveals two immunoglobulin-like domains.

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Nat Ecol Evol 8 (2) 282-292 [2024-02-00; online 2024-01-15]

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Proteomic profiling of tumour tissue-derived extracellular vesicles in colon cancer.

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J Extracell Biol 3 (2) e127 [2024-02-00; online 2024-02-06]

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Playing with Protic Additives to Improve the Outcome of Rhodium‐Catalyzed Hydroarylation of Fullerene C60 with Arylboronic Acids

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Oxylipin profiling by LC-ESI-MS/MS in canine serum and plasma to investigate ovulation-specific changes.

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MiCId GUI: The Graphical User Interface for MiCId, a Fast Microorganism Classification and Identification Workflow with Accurate Statistics and High Recall.

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J Comput Biol 31 (2) 175-178 [2024-02-00; online 2024-02-02]

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Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles.

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Humoral immune responses to the monovalent XBB.1.5-adapted BNT162b2 mRNA booster in Sweden.

Marking U, Bladh O, Aguilera K, ..., Sheward DJ, Thålin C

Lancet Infect Dis 24 (2) e80-e81 [2024-02-00; online 2024-01-05]

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Nature 626 (7998) 341-346 [2024-02-00; online 2024-01-31]

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Glycoproteomic profile of human tissue-nonspecific alkaline phosphatase expressed in osteoblasts.

Atanasova D, Mirgorodskaya E, Moparthi L, ..., Landberg E, Magnusson P

JBMR Plus 8 (2) ziae006 [2024-02-00; online 2024-01-22]

Genomic variation in montane bumblebees in Scandinavia: High levels of intraspecific diversity despite population vulnerability.

Liu Y, Olsson A, Larva T, ..., Cederberg B, Webster MT

Mol. Ecol. 33 (4) e17251 [2024-02-00; online 2023-12-19]

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Genetic diversity patterns in farmed rainbow trout (Oncorhynchus mykiss) populations using genome-wide SNP and haplotype data.

Longo A, Kurta K, Vanhala T, ..., de Koning DJ, Palaiokostas C

Anim Genet 55 (1) 87-98 [2024-02-00; online 2023-11-23]

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Gastrointestinal parasite community structure in horses after the introduction of selective anthelmintic treatment strategies.

Halvarsson P, Grandi G, Hägglund S, Höglund J

Vet Parasitol 326 (-) 110111 [2024-02-00; online 2023-12-25]

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Fine-scale genetic structure in the orchid Gymnadenia conopsea is not associated with local density of flowering plants.

Sletvold N, Joffard N, Söderquist L

Am. J. Bot. 111 (2) e16273 [2024-02-00; online 2024-01-30]

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Liu A, Akimova ET, Ding X, ..., Mills MC, Ganna A

Nat Hum Behav 8 (2) 276-287 [2024-02-00; online 2023-12-18]

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Correlates of Plasma Citrulline, a Potential Marker of Enterocyte Mass, among Children with Stunting: A Cross-Sectional Study in Uganda.

Pesu H, Mbabazi J, Mutumba R, ..., Friis H, Grenov B

J. Nutr. 154 (2) 765-776 [2024-02-00; online 2023-12-21]

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Complex In Vitro Model Characterization for Context of Use in Toxicologic Pathology: Use Cases by Collaborative Teams of Biologists, Bioengineers, and Pathologists.

Stokar-Regenscheit N, Bell L, Berridge B, ..., Sura R, Tomlinson L

Toxicol Pathol 52 (2-3) 123-137 [2024-02-00; online 2024-06-18]

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Schmied C, Nelson MS, Avilov S, ..., Tischer C, Jambor HK

Nat. Methods 21 (2) 170-181 [2024-02-00; online 2023-09-14]

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CPAP may promote an endothelial inflammatory milieu in sleep apnoea after coronary revascularization

Peker Y, Celik Y, Behboudi A, ..., Gottlieb DJ, Jelic S

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Antimicrobial susceptibilities and genomic characteristics of methicillin‐resistant Staphylococcus aureus resistant to mupirocin in Stockholm, Sweden

Vestberg N, Razavi M, Giske CG, Fang H

APMIS 132 (2) 94-99 [2024-02-00; online 2023-11-15]

A survey of ficolin-3 activity in Systemic Lupus Erythematosus reveals a link to hematological disease manifestations and autoantibody profile.

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J. Autoimmun. 143 (-) 103166 [2024-02-00; online 2024-01-13]

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A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.

Menon I, Sych T, Son Y, ..., Levitz J, Menon AK

J. Biol. Chem. 300 (2) 105649 [2024-02-00; online 2024-01-16]

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The role of recombination dynamics in shaping signatures of direct and indirect selection across the Ficedula flycatcher genome†.

Chase MA, Vilcot M, Mugal CF

Proc. Biol. Sci. 291 (2015) 20232382 [2024-01-31; online 2024-01-17]

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Discovery of lipid binding sites in a ligand-gated ion channel by integrating simulations and cryo-EM

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Batrachochytrium dendrobatidis strain affects transcriptomic response in liver but not skin in latitudinal populations of the common toad (Bufo bufo).

Chondrelli N, Kuehn E, Meurling S, ..., Laurila A, Höglund J

Sci Rep 14 (1) 2495 [2024-01-30; online 2024-01-30]

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A two-step activation mechanism enables mast cells to differentiate their response between extracellular and invasive enterobacterial infection.

von Beek C, Fahlgren A, Geiser P, ..., Pejler G, Sellin ME

Nat Commun 15 (1) 904 [2024-01-30; online 2024-01-30]

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Single-cell RNA-seq mapping of chicken peripheral blood leukocytes.

Maxwell M, Söderlund R, Härtle S, Wattrang E

BMC Genomics 25 (1) 124 [2024-01-29; online 2024-01-29]

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Dietary patterns, untargeted metabolite profiles and their association with colorectal cancer risk.

Bodén S, Zheng R, Ribbenstedt A, ..., Van Guelpen B, Brunius C

Sci Rep 14 (1) 2244 [2024-01-26; online 2024-01-26]

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Krzewińska M, Rodríguez-Varela R, Yaka R, ..., Storå J, Götherström A

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High-parametric protein maps reveal the spatial organization in early-developing human lung

Sariyar S, Sountoulidis A, Hansen JN, ..., Lundberg E, Ayoglu B

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Whole-genome sequencing in prenatally detected congenital malformations: prospective cohort study in clinical setting.

Westenius E, Conner P, Pettersson M, ..., Lindstrand A, Iwarsson E

Ultrasound Obstet Gynecol - (-) - [2024-01-24; online 2024-01-24]

The potential of liquid biopsy for detection of the KIAA1549-BRAF fusion in circulating tumor DNA from children with pilocytic astrocytoma.

Krynina O, de Ståhl TD, Jylhä C, ..., Tham E, Sandvik U

Neurooncol Adv 6 (1) vdae008 [2024-01-24; online 2024-01-24]

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QComics: Recommendations and Guidelines for Robust, Easily Implementable and Reportable Quality Control of Metabolomics Data.

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Anal. Chem. 96 (3) 1064-1072 [2024-01-23; online 2024-01-05]

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Genetic diversity and recent ancestry based on whole-genome sequencing of endangered Swedish cattle breeds.

Harish A, Lopes Pinto FA, Eriksson S, Johansson AM

BMC Genomics 25 (1) 89 [2024-01-22; online 2024-01-22]

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Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2.

Lenart K, Arcoverde Cerveira R, Hellgren F, ..., Smith G, Loré K

NPJ Vaccines 9 (1) 17 [2024-01-20; online 2024-01-20]

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Towards high-throughput parallel imaging and single-cell transcriptomics of microbial eukaryotic plankton.

Grujčić V, Saarenpää S, Sundh J, ..., Foster RA, Andersson AF

PLoS ONE 19 (1) e0296672 [2024-01-19; online 2024-01-19]

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Remodeling of the human skeletal muscle proteome found after long-term endurance training but not after strength training.

Emanuelsson EB, Arif M, Reitzner SM, ..., Sundberg CJ, Chapman MA

iScience 27 (1) 108638 [2024-01-19; online 2023-12-05]

Genotyping of SNPs in bread wheat at reduced cost from pooled experiments and imputation.

Clouard C, Nettelblad C

Theor. Appl. Genet. 137 (1) 26 [2024-01-19; online 2024-01-19]

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Metagenomic analysis of Mesolithic chewed pitch reveals poor oral health among stone age individuals.

Kırdök E, Kashuba N, Damlien H, ..., Aravena A, Götherström A

Sci Rep 13 (1) 22125 [2024-01-18; online 2024-01-18]

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Ciliate Grazing on the Bloom-Forming Microalga Gonyostomum semen.

Bergman I, Lindström ES, Sassenhagen I

Microb. Ecol. 87 (1) 33 [2024-01-18; online 2024-01-18]

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Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis.

Leo F, Lood R, Thomsson KA, ..., Svensäter G, Wickström C

Front Microbiol 15 (-) 1340109 [2024-01-18; online 2024-01-18]

Evaluation of Genetic or Cellular Impairments in Type I IFN Immunity in a Cohort of Young Adults with Critical COVID-19.

Covill LE, Sendel A, Campbell TM, ..., Bergman P, Bryceson YT

J Clin Immunol 44 (2) 50 [2024-01-17; online 2024-01-17]

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CircNetVis: an interactive web application for visualizing interaction networks of circular RNAs.

Nguyen TH, Nguyen HN, Vu TN

BMC Bioinformatics 25 (1) 31 [2024-01-17; online 2024-01-17]

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OMICs Signatures Linking Persistent Organic Pollutants to Cardiovascular Disease in the Swedish Mammography Cohort.

Schillemans T, Yan Y, Ribbenstedt A, ..., Åkesson A, Brunius C

Environ. Sci. Technol. 58 (2) 1036-1047 [2024-01-16; online 2024-01-04]

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High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

Andronico LA, Jiang Y, Carannante V, ..., Brodin P, Sezgin E

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Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.

Moura PL, Mortera-Blanco T, Hofman IJ, ..., Jacobsen SEW, Hellström-Lindberg E

Cancer Res. 84 (2) 211-225 [2024-01-16; online 2023-11-03]

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Ultralight Ultrafast Enzymes.

Zhang X, Meng Z, Beusch CM, ..., Gaetani M, Zubarev RA

Angew. Chem. Int. Ed. Engl. 63 (3) e202316488 [2024-01-15; online 2023-12-07]

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.

Drexhage LZ, Zhang S, Dupont M, ..., Karaji N, Sattentau QJ

Nat Commun 15 (1) 541 [2024-01-15; online 2024-01-15]

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Profiling of Surface Protein Epitopes on Viral Particles by Multiplex Dual-Reporter Strategy

Sahi M, Andersson S, Mattson C, ..., Chiodi F, Fredolini C

J Vis Exp - (203) - [2024-01-12; online 2024-01-12]

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Furan Distribution as a Severity Indicator upon Organosolv Fractionation of Hardwood Sawdust through a Novel Ternary Solvent System

Thoresen PP, Delgado Vellosillo I, Lange H, ..., Christakopoulos P, Matsakas L

ACS Sustainable Chem. Eng. - (-) - [2024-01-12; online 2024-01-12]

Differential expression and alternative splicing analyses of multiple tissues reveal albinism-associated genes in the Wels catfish (Silurus glanis).

Ozerov MY, Noreikiene K, Kahar S, ..., Gross R, Vasemägi A

Comp Biochem Physiol B Biochem Mol Biol 271 (-) 110941 [2024-01-11; online 2024-01-11]

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Identification of circulating autoantibodies to non-modified proteins associated with ACPA status in early rheumatoid arthritis.

Lourido L, Joshua V, Hansson M, ..., Klareskog L, Blanco FJ

Rheumatology (Oxford) - (-) - [2024-01-09; online 2024-01-09]

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Single-cell genomics of a bloom-forming phytoplankton species reveals population genetic structure across continents.

Gollnisch R, Ahrén D, Rengefors K

ISME J 18 (1) - [2024-01-08; online 2024-03-15]

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Separating phases of allopolyploid evolution with resynthesized and natural Capsella bursa-pastoris.

Duan T, Sicard A, Glémin S, Lascoux M

Elife 12 (-) - [2024-01-08; online 2024-01-08]

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Climate acts as an environmental filter to plant pathogens.

Caballol M, Redondo MÁ, Catalán N, ..., Stenlid J, Oliva J

ISME J 18 (1) - [2024-01-08; online 2024-02-17]

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Biotic interactions between benthic infauna and aerobic methanotrophs mediate methane fluxes from coastal sediments.

Broman E, Olsson M, Maciute A, ..., Bonaglia S, Nascimento FJA

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A pan-genomic approach reveals novel Sulfurimonas clade in the ferruginous meromictic Lake Pavin.

Biderre-Petit C, Courtine D, Hennequin C, ..., Divne A, Hochart C

Mol Ecol Resour - (-) e13923 [2024-01-08; online 2024-01-08]

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Antimicrobial Activity of Two Different Types of Silver Nanoparticles against Wide Range of Pathogenic Bacteria.

Holubnycha V, Husak Y, Korniienko V, ..., Ramanavicius A, Pogorielov M

Nanomaterials (Basel) 14 (2) - [2024-01-07; online 2024-01-07]

WOMBAT-P: Benchmarking Label-Free Proteomics Data Analysis Workflows.

Bouyssié D, Altıner P, Capella-Gutierrez S, ..., Winkelhardt D, Schwämmle V

J. Proteome Res. 23 (1) 418-429 [2024-01-05; online 2023-12-01]

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Sex-limited experimental evolution drives transcriptomic divergence in a hermaphrodite.

Cīrulis A, Nordén AK, Churcher AM, ..., Zadesenets KS, Abbott JK

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Proteomic analysis shows decreased type I fibers and ectopic fat accumulation in skeletal muscle from women with PCOS.

Stener-Victorin E, Eriksson G, Mohan Shrestha M, ..., Lanner J, Benrick A

Elife 12 (-) - [2024-01-05; online 2024-01-05]

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence.

Kohler V, Kohler A, Berglund LL, ..., Andréasson C, Büttner S

Nat Commun 15 (1) 315 [2024-01-05; online 2024-01-05]

Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model.

Ibrahim EIK, Ellingsen EB, Mangsbo SM, Friberg LE

Int Immunopharmacol 126 (-) 111225 [2024-01-05; online 2023-11-20]

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Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations.

Kojima R, Paslawski W, Lyu G, ..., Zhang X, Svenningsson P

Int J Mol Sci 25 (1) - [2024-01-04; online 2024-01-04]

METTL17 is an Fe-S cluster checkpoint for mitochondrial translation.

Ast T, Itoh Y, Sadre S, ..., Amunts A, Mootha VK

Mol. Cell - (-) - [2024-01-04; online 2024-01-04]

Exonic trinucleotide repeat expansions in ZFHX3 cause spinocerebellar ataxia type 4: A poly-glycine disease.

Wallenius J, Kafantari E, Jhaveri E, ..., Ehrencrona H, Puschmann A

Am. J. Hum. Genet. 111 (1) 82-95 [2024-01-04; online 2023-11-29]

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Elevated circulating adiponectin levels do not prevent anxiety-like behavior in a PCOS-like mouse model.

Samad M, Ek J, Börchers S, ..., Asterholm IW, Benrick A

Sci Rep 14 (1) 563 [2024-01-04; online 2024-01-04]

Mutation of the cyclooxygenase 2 gene promoter and anastomotic leakage in colorectal cancer patients: retrospective cohort study.

Grahn O, Holmgren K, Hong MG, Sund M, Rutegård M

BJS Open 8 (1) - [2024-01-03; online 2024-01-30]

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Identification of a Notch transcriptomic signature for breast cancer.

Braune EB, Geist F, Tang X, ..., Wienke D, Lendahl U

Breast Cancer Res. 26 (1) 4 [2024-01-03; online 2024-01-03]

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Tissue-specific RNA Polymerase II promoter-proximal pause release and burst kinetics in a Drosophila embryonic patterning network.

Hunt G, Vaid R, Pirogov S, ..., Reimegård J, Mannervik M

Genome Biol. 25 (1) 2 [2024-01-02; online 2024-01-02]

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Functional annotation of a divergent genome using sequence and structure-based similarity.

Svedberg D, Winiger RR, Berg A, ..., Vossbrinck CR, Barandun J

BMC Genomics 25 (1) 6 [2024-01-02; online 2024-01-02]

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A comprehensive dataset on spatiotemporal variation of microbial plankton communities in the Baltic Sea.

Latz MAC, Andersson A, Brugel S, ..., Torstensson A, Andersson AF

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Metastasis and recurrence patterns in the molecular subtypes of urothelial bladder cancer.

Sjödahl G, Eriksson P, Holmsten K, ..., Ullén A, Liedberg F

Int. J. Cancer 154 (1) 180-190 [2024-01-01; online 2023-09-06]

Global Transcriptome Analysis Reveals Distinct Phases of the Endothelial Response to TNF.

Struck EC, Belova T, Hsieh PH, ..., Dusart PJ, Butler LM

J. Immunol. 212 (1) 117-129 [2024-01-01; online 2023-11-29]

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Astrocytic Regulation of Endocannabinoid-Dependent Synaptic Plasticity in the Dorsolateral Striatum.

Adermark L, Stomberg R, Söderpalm B, Ericson M

Int J Mol Sci 25 (1) - [2024-01-01; online 2024-01-01]

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Analysis of stabilization mechanisms in β-lactoglobulin-based amorphous solid dispersions by experimental and computational approaches.

Zhuo X, Foderà V, Larsson P, ..., Löbmann K, Kabedev A

Eur J Pharm Sci 192 (-) 106639 [2024-01-01; online 2023-11-13]

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A biobased binder of carboxymethyl cellulose, citric acid, chitosan and wheat gluten for nonwoven and paper.

Wennman M, Pinon AC, Svagan AJ, Hellberg M, Hedenqvist MS

Carbohydr Polym 323 (-) 121430 [2024-01-01; online 2023-09-23]

pyngoST: fast, simultaneous and accurate multiple sequence typing of Neisseria gonorrhoeae genome collections.

Sánchez-Busó L, Sánchez-Serrano A, Golparian D, Unemo M

Microb Genom 10 (1) - [2024-01-00; online 2024-01-30]

Whole-genome selective sweep analyses identifies the region and candidate gene associated with white earlobe color in Mediterranean chickens.

Guo Y, Rubin CJ, Rönneburg T, ..., Hu X, Carlborg Ö

Poult. Sci. 103 (1) 103232 [2024-01-00; online 2023-10-24]

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The genetic legacy of the expansion of Bantu-speaking peoples in Africa.

Fortes-Lima CA, Burgarella C, Hammarén R, ..., Bostoen K, Schlebusch CM

Nature 625 (7995) 540-547 [2024-01-00; online 2023-11-29]

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The functional role of CST1 and CCL26 in asthma development.

Hoyer A, Chakraborty S, Lilienthal I, ..., Katayama S, Söderhäll C

Immun Inflamm Dis 12 (1) e1162 [2024-01-00; online 2024-01-25]

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Substance P, NPY, CCK and their receptors in five brain regions in major depressive disorder with transcriptomic analysis of locus coeruleus neurons.

Barde S, Aguila J, Zhong W, ..., Hedlund E, Hökfelt T

Eur Neuropsychopharmacol 78 (-) 54-63 [2024-01-00; online 2023-11-04]

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Randomized open-label trial of semaglutide and dapagliflozin in patients with type 2 diabetes of different pathophysiology.

Dwibedi C, Ekström O, Brandt J, ..., Abrahamsson B, Rosengren AH

Nat Metab 6 (1) 50-60 [2024-01-00; online 2024-01-04]

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Pulmonary function and atherosclerosis in the general population: causal associations and clinical implications.

Engström G, Lampa E, Dekkers K, ..., Östgren CJ, Sundström J

Eur. J. Epidemiol. 39 (1) 35-49 [2024-01-00; online 2024-01-02]

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Prognostic value of hypoxia-responsive gene expression profile in patients diagnosed with head and neck squamous cell carcinoma.

Matic N, Pettersson L, Sellebjerg F, ..., Roberg K, Wiechec E

Transl Oncol 39 (-) 101841 [2024-01-00; online 2023-11-27]

Population genomics of the muskox' resilience in the near absence of genetic variation.

Pečnerová P, Lord E, Garcia-Erill G, ..., Moltke I, Siegismund HR

Mol. Ecol. 33 (2) e17205 [2024-01-00; online 2023-11-16]

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Phylogenomics and topological conflicts in the tribe Anthospermeae (Rubiaceae).

Thureborn O, Wikström N, Razafimandimbison SG, Rydin C

Ecol Evol 14 (1) e10868 [2024-01-00; online 2024-01-25]

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Phylogenetics and environmental distribution of nitric oxide-forming nitrite reductases reveal their distinct functional and ecological roles.

Pold G, Bonilla-Rosso G, Saghaï A, ..., Jones CM, Hallin S

ISME COMMUN. 4 (1) ycae020 [2024-01-00; online 2024-02-02]

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Novel candidate taxa contribute to key metabolic processes in Fennoscandian Shield deep groundwaters.

Dopson M, Rezaei Somee M, González-Rosales C, ..., Mehrshad M, Bertilsson S

ISME COMMUN. 4 (1) ycae113 [2024-01-00; online 2024-09-23]

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New indicators for monitoring genetic diversity applied to alpine brown trout populations using whole genome sequence data.

Kurland S, Saha A, Keehnen N, ..., Ryman N, Laikre L

Mol. Ecol. 33 (2) e17213 [2024-01-00; online 2023-11-28]

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New chemical and microbial perspectives on vitamin B1 and vitamer dynamics of a coastal system.

Bittner MJ, Bannon CC, Rowland E, ..., Paerl RW, Riemann L

ISME COMMUN. 4 (1) ycad016 [2024-01-00; online 2024-01-10]

Bioinformatics Support and Infrastructure [Service] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors.

FitzGerald EA, Vagrys D, Opassi G, ..., de Esch IJP, Danielson UH

SLAS DISCOVERY: Advancing Life Sciences R&D 29 (1) 40-51 [2024-01-00; online 2023-09-14]

Chemical Biology Consortium Sweden (CBCS) [Service] Drug Discovery and Development (DDD) [Service]

Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise – A systems biology approach

Reitzner SM, Emanuelsson EB, Arif M, ..., Chapman MA, Sundberg CJ

Mol Metab 79 (-) 101857 [2024-01-00; online 2024-01-00]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre (SMC) [Service]

Molecular blueprints for spinal circuit modules controlling locomotor speed in zebrafish.

Pallucchi I, Bertuzzi M, Madrid D, ..., Higashijima SI, El Manira A

Nat. Neurosci. 27 (1) 78-89 [2024-01-00; online 2023-11-02]

NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Heat inactivation of foetal bovine serum performed after EV-depletion influences the proteome of cell-derived extracellular vesicles.

Urzì O, Bergqvist M, Lässer C, ..., Olofsson Bagge R, Crescitelli R

J Extracell Vesicles 13 (1) e12408 [2024-01-00; online 2024-01-24]

Glycoproteomics and MS Proteomics [Service] Integrated Microscopy Technologies Gothenburg [Service]

Effects of Wholegrain Compared to Refined Grain Intake on Cardiometabolic Risk Markers, Gut Microbiota, and Gastrointestinal Symptoms in Children: A Randomized Crossover Trial.

Madsen MTB, Landberg R, Nielsen DS, ..., Lauritzen L, Damsgaard CT

Am. J. Clin. Nutr. 119 (1) 18-28 [2024-01-00; online 2023-10-28]

Chalmers Mass Spectrometry Infrastructure [Collaborative]

Distinct molecular targets of ProEGCG from EGCG and superior inhibition of angiogenesis signaling pathways for treatment of endometriosis.

Hung SW, Gaetani M, Li Y, ..., Zubarev RA, Wang CC

J Pharm Anal 14 (1) 100-114 [2024-01-00; online 2023-09-11]

DNA metabarcoding reveals spatial and temporal variation of fish eye fluke communities in lake ecosystems.

Diaz-Suarez A, Noreikiene K, Kahar S, ..., Kisand V, Vasemägi A

Int J Parasitol 54 (1) 33-46 [2024-01-00; online 2023-08-24]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Compound heterozygous variants in RAB34 in a rare skeletal ciliopathy syndrome.

Batkovskyte D, Komatsu M, Hammarsjö A, ..., Nishimura G, Yamada T

Clin. Genet. 105 (1) 87-91 [2024-01-00; online 2023-08-24]

Bioinformatics Support for Computational Resources [Service] Clinical Genomics Stockholm [Service]

Birth Weight, Childhood and Young Adult Overweight, and the Risk of Coronary Heart Disease in Men.

Bramsved R, Bygdell M, Martikainen J, ..., Ohlsson C, Kindblom JM

Arterioscler. Thromb. Vasc. Biol. 44 (1) 314-321 [2024-01-00; online 2023-11-16]

A conserved graft formation process in Norway spruce and Arabidopsis identifies the PAT gene family as central regulators of wound healing.

Feng M, Zhang A, Nguyen V, ..., Carlsbecker A, Melnyk CW

NPLANTS 10 (1) 53-65 [2024-01-00; online 2024-01-02]

Bioinformatics Support for Computational Resources [Service]

Visualizing the Microbial N Uptake During Arctic Extreme Winter Warming Events Using Nanosims

Rasmussen LH, Danielsen BK, Elberling B, ..., Micaroni M, Andresen LC

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Integrated Microscopy Technologies Gothenburg [Service]

Strategies for Multimodal Image Data Transformation to a Common Format for Cloud Integration and Visualization

Camacho R, Berndtsson J, Micaroni M, Zhang K, Fernandez-Rodriguez J

BIO Web Conf. 129 (-) 13019 [2024-00-00; online 2024-10-17]

Integrated Microscopy Technologies Gothenburg [Service]

Population genomic data reveal low genetic diversity, divergence and local adaptation among threatened Reeves's Pheasant (Syrmaticus reevesii)

Lu Q, Wang P, Chang J, ..., Höglund J, Zhang Z

Avian Research 15 (-) 100156 [2024-00-00; online 2024-00-00]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

One-pot reductive liquefaction of sawdust to renewables over MoOx–Al2O3 variants: insight into structure–activity relationships

Salam MA, Tran QK, Ho PH, ..., Olsson L, Creaser D

Sustainable Energy Fuels 8 (12) 2668-2681 [2024-00-00; online 2024-00-00]

Landscape of Epstein-Barr virus gene expression and perturbations in cancer

K. W. Tang YTGXABIHDVea

Res Sq - (-) - [2024-00-00]

Ionic liquid strategy for chitosan production from chitin and molecular insights

Dinh VM, Khokarale SG, May PO, ..., Irgum K, Mikkola JP

RSC Sustain. 2 (4) 1154-1164 [2024-00-00; online 2024-00-00]

A surface passivated fluorinated polymer nanocomposite for carbon monoxide resistant plasmonic hydrogen sensing

Östergren I, Darmadi I, Lerch S, ..., Langhammer C, Müller C

J. Mater. Chem. A 12 (13) 7906-7915 [2024-00-00; online 2024-00-00]

Integrated Microscopy Technologies Gothenburg [Service]