Kerkhoven EJ

Reprogramming Yarrowia lipolytica metabolism for efficient synthesis of itaconic acid from flask to semipilot scale.

Fu J, Zaghen S, Lu H, ..., Di Bartolomeo F, Kerkhoven EJ

Sci Adv 10 (32) eadn0414 [2024-08-09; online 2024-08-09]

Chalmers Mass Spectrometry Infrastructure [Service]

ReprogrammingYarrowia lipolyticametabolism for efficient synthesis of itaconic acid from flask to semi-pilot scale

Fu J, Zaghen S, Lu H, ..., Di Bartolomeo F, Kerkhoven EJ

- - (-) - [2023-07-18; online 2023-07-18]

Chalmers Mass Spectrometry Infrastructure [Service]

Abolishing storage lipids induces protein misfolding and stress responses in Yarrowia lipolytica.

Zaghen S, Konzock O, Fu J, Kerkhoven EJ

J Ind Microbiol Biotechnol 50 (1) - [2023-02-17; online 2023-09-24]

Bioinformatics Support for Computational Resources [Service] Chalmers Mass Spectrometry Infrastructure [Service]

Generation and analysis of context-specific genome-scale metabolic models derived from single-cell RNA-Seq data.

Gustafsson J, Anton M, Roshanzamir F, ..., Robinson JL, Nielsen J

Proc. Natl. Acad. Sci. U.S.A. 120 (6) e2217868120 [2023-02-07; online 2023-01-31]

Bioinformatics Support, Infrastructure and Training [Collaborative] Systems Biology [Collaborative]

Validated Growth Rate-Dependent Regulation of Lipid Metabolism in Yarrowia lipolytica.

Poorinmohammad N, Fu J, Wabeke B, Kerkhoven EJ

Int J Mol Sci 23 (15) - [2022-07-31; online 2022-07-31]

Glycoproteomics and MS Proteomics [Service]

Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0.

Domenzain I, Sánchez B, Anton M, ..., Sonnenschein N, Nielsen J

Nat Commun 13 (1) 3766 [2022-06-30; online 2022-06-30]

Bioinformatics Support, Infrastructure and Training [Collaborative] Systems Biology [Collaborative]

Adaptations in metabolism and protein translation give rise to the Crabtree effect in yeast.

Malina C, Yu R, Björkeroth J, Kerkhoven EJ, Nielsen J

Proc. Natl. Acad. Sci. U.S.A. 118 (51) - [2021-12-21; online 2021-12-15]

Glycoproteomics and MS Proteomics [Service]

An atlas of human metabolism.

Robinson JL, Kocabaş P, Wang H, ..., Uhlén M, Nielsen J

Sci Signal 13 (624) - [2020-03-24; online 2020-03-24]

Bioinformatics Support, Infrastructure and Training [Technology development] Systems Biology [Technology development]

RAVEN 2.0: A versatile toolbox for metabolic network reconstruction and a case study on Streptomyces coelicolor.

Wang H, Marcišauskas S, Sánchez BJ, ..., Nielsen J, Kerkhoven EJ

PLoS Comput. Biol. 14 (10) e1006541 [2018-10-00; online 2018-10-18]

Bioinformatics Support, Infrastructure and Training [Technology development] Systems Biology [Technology development]