ACS Chem Neurosci

Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer's Disease Following Treatment with a Brain-Targeting Somatostatin Peptide.

Rofo F, Sandbaumhüter FA, Chourlia A, ..., Jansson ET, Hultqvist G

ACS Chem Neurosci 12 (13) 2529-2541 [2021-07-07; online 2021-06-25]

Spatial Mass Spectrometry [Collaborative]

Cooperativity of α-Synuclein Binding to Lipid Membranes.

Makasewicz K, Wennmalm S, Stenqvist B, ..., Linse S, Sparr E

ACS Chem Neurosci 12 (12) 2099-2109 [2021-06-16; online 2021-06-02]

Integrated Microscopy Technologies Stockholm [Collaborative]

Integration of Mass Spectrometry Imaging and Machine Learning Visualizes Region-Specific Age-Induced and Drug-Target Metabolic Perturbations in the Brain.

Vallianatou T, Shariatgorji R, Nilsson A, ..., Svenningsson P, Andrén PE

ACS Chem Neurosci 12 (10) 1811-1823 [2021-05-19; online 2021-05-03]

Spatial Mass Spectrometry [Technology development]

Interaction between Copper Chaperone Atox1 and Parkinson's Disease Protein α-Synuclein Includes Metal-Binding Sites and Occurs in Living Cells.

Horvath I, Blockhuys S, Šulskis D, ..., Burmann BM, Wittung-Stafshede P

ACS Chem Neurosci 10 (11) 4659-4668 [2019-11-20; online 2019-10-24]

Swedish NMR Centre (SNC) [Service]

Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant.

Khan MAI, Respondek M, Kjellström S, ..., Linse S, Akke M

ACS Chem Neurosci 8 (9) 2019-2026 [2017-09-20; online 2017-06-20]

Structural Proteomics [Service]

Delineating Amyloid Plaque Associated Neuronal Sphingolipids in Transgenic Alzheimer's Disease Mice (tgArcSwe) Using MALDI Imaging Mass Spectrometry.

Kaya I, Brinet D, Michno W, ..., Blennow K, Hanrieder J

ACS Chem Neurosci 8 (2) 347-355 [2017-02-15; online 2017-01-10]

Integrated Microscopy Technologies Gothenburg [Service]

Aryl Sulfonamide Inhibitors of Insulin-Regulated Aminopeptidase Enhance Spine Density in Primary Hippocampal Neuron Cultures.

Diwakarla S, Nylander E, Grönbladh A, ..., Chai SY, Hallberg M

ACS Chem Neurosci 7 (10) 1383-1392 [2016-10-19; online 2016-08-08]

Chemical Biology Consortium Sweden (CBCS) [Collaborative] Drug Discovery and Development (DDD) [Collaborative]