Mol. Cell

FBXL12 degrades FANCD2 to regulate replication recovery and promote cancer cell survival under conditions of replication stress.

Brunner A, Li Q, Fisicaro S, ..., Orre LM, Sangfelt O

Mol. Cell 83 (20) 3720-3739.e8 [2023-10-19; online 2023-08-16]

Global Proteomics and Proteogenomics [Collaborative]

MYC assembles and stimulates topoisomerases 1 and 2 in a "topoisome".

Das SK, Kuzin V, Cameron DP, ..., Levens D, Baranello L

Mol. Cell 82 (1) 140-158.e12 [2022-01-06; online 2021-12-09]

CRISPR Functional Genomics [Service]

(p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains.

Roghanian M, Van Nerom K, Takada H, ..., Garcia-Pino A, Hauryliuk V

Mol. Cell 81 (16) 3310-3322.e6 [2021-08-19; online 2021-08-21]

Structural Proteomics [Collaborative]

Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP.

Crowe-McAuliffe C, Takada H, Murina V, ..., Wilson DN, Hauryliuk V

Mol. Cell 81 (1) 115-126.e7 [2021-01-07; online 2020-11-30]

Cryo-EM [Service]

Dinucleotide Degradation by REXO2 Maintains Promoter Specificity in Mammalian Mitochondria.

Nicholls TJ, Spåhr H, Jiang S, ..., Larsson NG, Gustafsson CM

Mol. Cell 76 (5) 784-796.e6 [2019-12-05; online 2019-10-03]

Bioinformatics Compute and Storage [Service] Protein Science Facility (PSF) [Service]

SubCellBarCode: Proteome-wide Mapping of Protein Localization and Relocalization.

Orre LM, Vesterlund M, Pan Y, ..., Fredlund E, Lehtiö J

Mol. Cell 73 (1) 166-182.e7 [2019-01-03; online 2019-01-05]

Bioinformatics Compute and Storage [Service] Global Proteomics and Proteogenomics [Technology development]

A Unique ISR Program Determines Cellular Responses to Chronic Stress.

Guan BJ, van Hoef V, Jobava R, ..., Larsson O, Hatzoglou M

Mol. Cell 68 (5) 885-900.e6 [2017-12-07; online 2017-12-09]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

PARP1- and CTCF-Mediated Interactions between Active and Repressed Chromatin at the Lamina Promote Oscillating Transcription.

Zhao H, Sifakis EG, Sumida N, ..., Imreh MP, Göndör A

Mol. Cell 59 (6) 984-997 [2015-09-17; online 2015-08-27]

NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure