Nordenfelt P

Dissecting the properties of circulating IgG against Group A Streptococcus through a combined systems antigenomics-serology workflow

Chowdhury S, Gomez Toledo A, Hjortswang E, ..., Rasmussen M, Malmström J

- - (-) - [2023-11-09; online 2023-11-09]

Structural Proteomics [Collaborative]

Reply to Pandey: IgG3 allotypes, modulation of antigen binding by constant domain changes, and therapeutic applications of Fc engineering.

Izadi A, Bahnan W, Ohlin M, Nordenfelt P

Proc. Natl. Acad. Sci. U.S.A. 120 (22) e2306562120 [2023-05-30; online 2023-05-22]

Drug Discovery and Development (DDD) [Service]

Subclass-switched anti-spike IgG3 oligoclonal cocktails strongly enhance Fc-mediated opsonization.

Izadi A, Hailu A, Godzwon M, ..., Bahnan W, Nordenfelt P

Proc. Natl. Acad. Sci. U.S.A. 120 (15) e2217590120 [2023-04-11; online 2023-04-03]

Drug Discovery and Development (DDD) [Service]

A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function.

Bahnan W, Happonen L, Khakzad H, ..., Malmström J, Nordenfelt P

EMBO Mol Med 15 (2) e16208 [2023-02-08; online 2022-12-12]

Structural Proteomics [Collaborative]

Developmental cues license megakaryocyte priming in murine hematopoietic stem cells.

Kristiansen TA, Zhang Q, Vergani S, ..., Ungerbäck J, Yuan J

Blood Adv 6 (24) 6228-6241 [2022-12-27; online 2022-05-19]

Clinical Genomics Lund [Service]