Schüler H

System-wide identification and prioritization of enzyme substrates by thermal analysis.

Saei AA, Beusch CM, Sabatier P, ..., Schüler H, Zubarev RA

Nat Commun 12 (1) 1296 [2021-02-26; online 2021-02-26]

Chemical Proteomics [Technology development]

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins.

Nowak K, Rosenthal F, Karlberg T, ..., Leslie Pedrioli DM, Hottiger MO

Nat Commun 11 (1) 5199 [2020-10-15; online 2020-10-15]

Protein Science Facility (PSF) [Service]

A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.

Yuen LH, Dana S, Liu Y, ..., Schüler H, Franzini RM

J. Am. Chem. Soc. 141 (13) 5169-5181 [2019-04-03; online 2019-03-19]

Protein Science Facility (PSF) [Service]

14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface.

Karlberg T, Hornyak P, Pinto AF, ..., Björkegren C, Schüler H

Nat Commun 9 (1) 3785 [2018-09-17; online 2018-09-17]

Bioinformatics Support for Computational Resources [Service] Protein Science Facility (PSF) [Service]