Tang D

Multimodal Mass Spectrometry Identifies a Conserved Protective Epitope in S. pyogenes Streptolysin O

Tang D, Gueto-Tettay C, Hjortswang E, ..., Malmström L, Malmström J

Anal. Chem. 96 (22) 9060-9068 [2024-06-04; online 2024-05-03]

Structural Proteomics [Technology development]

The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies.

Izadi A, Karami Y, Bratanis E, ..., Malmström L, Nordenfelt P

Nat Commun 15 (1) 3600 [2024-04-27; online 2024-04-27]

Drug Discovery and Development (DDD) [Service]

A human monoclonal antibody bivalently binding two different epitopes in streptococcal M protein mediates immune function.

Bahnan W, Happonen L, Khakzad H, ..., Malmström J, Nordenfelt P

EMBO Mol Med 15 (2) e16208 [2023-02-08; online 2022-12-12]

Structural Proteomics [Collaborative]

Multienzyme deep learning models improve peptide de novo sequencing by mass spectrometry proteomics.

Gueto-Tettay C, Tang D, Happonen L, ..., Malmström J, Malmström L

PLoS Comput. Biol. 19 (1) e1010457 [2023-01-00; online 2023-01-20]

Structural Proteomics [Technology development]