Gaetani M

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Family name Gaetani
Given name Massimiliano
Initials M
ORCID

ORCID 0000-0001-5610-0797
Affiliations Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.
SciLifeLab, Stockholm, Sweden.
Chemical Proteomics Core Facility, Division of Physiological Chemistry I, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

16 publications

PubMed DOI Crossref
One-Pot Time-Induced Proteome Integral Solubility Alteration Assay for Automated and Sensitive Drug-Target Identification.
Meng Z, Saei AA, Lyu H, Gaetani M, Zubarev RA
Anal. Chem. - (-) - [2024-11-20; online 2024-11-20]
Chemical Proteomics [Technology development]
PubMed DOI Crossref
Gel-Assisted Proteome Position Integral Shift Assay Returns Molecular Weight to Shotgun Proteomics and Identifies Caspase 3 Substrates.
Meng Z, Saei AA, Gharibi H, ..., Gaetani M, Zubarev RA
Anal. Chem. 96 (33) 13533-13541 [2024-08-20; online 2024-08-07]
Chemical Proteomics [Technology development]
PubMed DOI Crossref
A chemical inhibitor of IST1-CHMP1B interaction impairs endosomal recycling and induces noncanonical LC3 lipidation.
Knyazeva A, Li S, Corkery DP, ..., Waldmann H, Wu YW
Proc. Natl. Acad. Sci. U.S.A. 121 (17) e2317680121 [2024-04-23; online 2024-04-18]
Chemical Proteomics [Collaborative] Cryo-EM [Service]
DOI Crossref
Chemogenetic inhibition of IST1-CHMP1B interaction impairs endosomal recycling and promotes unconventional LC3 lipidation at stalled endosomes
Knyazeva A, Li S, Corkery DP, ..., Waldmann H, Wu YW
- - (-) - [2023-08-28; online 2023-08-28]
Chemical Proteomics [Collaborative]
PubMed DOI Crossref
Proteome integral solubility alteration high-throughput proteomics assay identifies Collectin-12 as a non-apoptotic microglial caspase-3 substrate.
Grabert K, Engskog-Vlachos P, Škandík M, ..., Joseph B, Cheray M
Cell Death Dis 14 (3) 192 [2023-03-11; online 2023-03-11]
Chemical Proteomics [Collaborative]
PubMed DOI Crossref
DAR 16-II Primes Endothelial Cells for Angiogenesis Improving Bone Ingrowth in 3D-Printed BCP Scaffolds and Regeneration of Critically Sized Bone Defects.
Alfayez E, Veschini L, Dettin M, ..., Coward T, Di Silvio L
Biomolecules 12 (11) 1619 [2022-11-02; online 2022-11-02]
Chemical Proteomics [Collaborative]
PubMed DOI Crossref
Proteomics-Compatible Fourier Transform Isotopic Ratio Mass Spectrometry of Polypeptides.
Gharibi H, Chernobrovkin AL, Saei AA, ..., Makarov AA, Zubarev RA
Anal. Chem. 94 (43) 15048-15056 [2022-11-01; online 2022-10-17]
Chemical Proteomics [Technology development]
PubMed DOI Crossref
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation.
Sabatier P, Beusch CM, Saei AA, ..., Rodin S, Zubarev RA
Nat Commun 12 (1) 6558 [2021-11-12; online 2021-11-12]
Chemical Proteomics [Technology development]
PubMed DOI Crossref
System-wide identification and prioritization of enzyme substrates by thermal analysis.
Saei AA, Beusch CM, Sabatier P, ..., Schüler H, Zubarev RA
Nat Commun 12 (1) 1296 [2021-02-26; online 2021-02-26]
Chemical Proteomics [Technology development]
PubMed DOI Crossref
Capillary leakage provides nutrients and antioxidants for rapid pneumococcal proliferation in influenza-infected lower airways.
Sender V, Hentrich K, Pathak A, ..., Normark S, Henriques-Normark B
Proc. Natl. Acad. Sci. U.S.A. 117 (49) 31386-31397 [2020-12-08; online 2020-11-23]
Bioinformatics Support for Computational Resources [Service] Chemical Proteomics [Collaborative]
PubMed DOI Crossref
Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171.
Subramaniam A, Žemaitis K, Talkhoncheh MS, ..., Zubarev RA, Larsson J
Blood 136 (19) 2151-2161 [2020-11-05; online 2020-06-26]
Bioinformatics Support for Computational Resources [Service] Chemical Proteomics [Collaborative]
PubMed DOI Crossref
Thermal Proteome Profiling Identifies Oxidative-Dependent Inhibition of the Transcription of Major Oncogenes as a New Therapeutic Mechanism for Select Anticancer Compounds.
Peuget S, Zhu J, Sanz G, ..., Zubarev R, Selivanova G
Cancer Res. 80 (7) 1538-1550 [2020-04-01; online 2020-02-04]
Chemical Proteomics [Collaborative]
PubMed DOI Crossref
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
Saei AA, Beusch CM, Chernobrovkin A, ..., Végvári Á, Zubarev RA
Nat Commun 10 (1) 5715 [2019-12-00; online 2019-12-16]
Chemical Proteomics [Technology development]
PubMed DOI Crossref
Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution.
Gaetani M, Sabatier P, Saei AA, ..., Lundström SL, Zubarev RA
J. Proteome Res. 18 (11) 4027-4037 [2019-11-01; online 2019-10-14]
Chemical Proteomics [Technology development]
DOI Crossref
Functional Identification of Target by Expression Proteomics (FITExP)
Gaetani M, Zubarev RA
- - (-) 257-266 [2019-08-13; online 2019-07-26]
Chemical Proteomics [Technology development]
DOI Crossref
New Promises of Chemical Proteomics for Drug Development
Gaetani M, Zubarev RA
Novel Approaches in Drug Designing & Development 2 (1) 555579 [2017-06-27]
Chemical Proteomics [Technology development]
SciLifeLab Data Centre
Publications 9.5.1