Tissue Profiling

SciLifeLab National facility between 2013 - 2018.

178 publications

Year 2017

PubMed DOI Crossref
Breast cancer in young women and prognosis: How important are proliferation markers?
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
Eur. J. Cancer 84 (-) 278-289 [2017-10-00; online 2017-08-29]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Associations of defect mismatch repair genes with prognosis and heredity in sporadic colorectal cancer.
Ghanipour L, Jirström K, Sundström M, Glimelius B, Birgisson H
Eur J Surg Oncol 43 (2) 311-321 [2017-02-00; online 2016-11-12]
Tissue Profiling [Service]
PubMed DOI Crossref
Perivascular PDGFR-β is an independent marker for prognosis in renal cell carcinoma.
Frödin M, Mezheyeuski A, Corvigno S, ..., Johansson M, Östman A
pmc
Br. J. Cancer 116 (2) 195-201 [2017-01-17; online 2016-12-09]
Tissue Profiling [Service]

Year 2016

PubMed DOI Crossref
The protein phosphatase 2A regulatory subunit PR70 is a gonosomal melanoma tumor suppressor gene.
van Kempen LC, Redpath M, Elchebly M, ..., Feunteun J, Spatz A
Sci Transl Med 8 (369) 369ra177 [2016-12-14; online 2016-12-16]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Looking for Missing Proteins in the Proteome of Human Spermatozoa: An Update.
Vandenbrouck Y, Lane L, Carapito C, ..., Garin J, Pineau C
J. Proteome Res. 15 (11) 3998-4019 [2016-11-04; online 2016-08-23]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Long-term outcome in young women with breast cancer: a population-based study.
Fredholm H, Magnusson K, Lindström LS, ..., Frisell J, Fredriksson I
pmc
Breast Cancer Res. Treat. 160 (1) 131-143 [2016-11-00; online 2016-09-13]
Tissue Profiling [Collaborative]
DOI Crossref
Gene‐specific correlation of RNA and protein levels in human cells and tissues
Edfors F, Danielsson F, Hallström BM, ..., Forsström B, Uhlén M
Mol. Syst. Biol. 12 (10) 883 [2016-10-00; online 2016-10-20]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Analysis of Body-wide Unfractionated Tissue Data to Identify a Core Human Endothelial Transcriptome.
Butler LM, Hallström BM, Fagerberg L, ..., Renné T, Odeberg J
Cell Syst 3 (3) 287-301.e3 [2016-09-28; online 2016-09-15]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Tissue microarray profiling in human heart failure.
Lal S, Nguyen L, Tezone R, ..., Li A, Dos Remedios C
Proteomics 16 (17) 2319-2326 [2016-09-00; online 2016-08-11]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Inconsistent results in the analysis of ALK rearrangements in non-small cell lung cancer.
Mattsson JS, Brunnström H, Jabs V, ..., Micke P, Svensson MA
pmc
BMC Cancer 16 (-) 603 [2016-08-05; online 2016-08-05]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
SATB2 is expressed in Merkel cell carcinoma.
Fukuhara M, Agnarsdóttir M, Edqvist PH, Coter A, Ponten F
Arch. Dermatol. Res. 308 (6) 449-454 [2016-08-00; online 2016-06-04]
Tissue Profiling [Technology development]
PubMed DOI Crossref
System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.
Pozniak Y, Balint-Lahat N, Rudolph JD, ..., Barshack I, Geiger T
Cell Syst 2 (3) 172-184 [2016-03-23; online 2016-03-03]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Oncogene-Induced Senescence in Pituitary Adenomas--an Immunohistochemical Study.
Manojlovic-Gacic E, Skender-Gazibara M, Popovic V, ..., Pontén F, Casar-Borota O
Endocr. Pathol. 27 (1) 1-11 [2016-03-00; online 2015-11-18]
Tissue Profiling [Collaborative]

Year 2015

PubMed DOI Crossref
High levels of WNT-5A in human glioma correlate with increased presence of tumor-associated microglia/monocytes.
Dijksterhuis JP, Arthofer E, Marinescu VD, ..., Mulder J, Schulte G
Exp. Cell Res. 339 (2) 280-288 [2015-12-10; online 2015-10-25]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFR.
Vizoso M, Ferreira HJ, Lopez-Serra P, ..., Marais R, Esteller M
pmc mid
Nat. Med. 21 (7) 741-750 [2015-07-00; online 2015-06-01]
Tissue Profiling [Collaborative]

Year 2014

PubMed DOI Crossref
Aberrantly activated claudin 6 and 18.2 as potential therapy targets in non-small-cell lung cancer.
Micke P, Mattsson JS, Edlund K, ..., Sahin U, Türeci O
Int. J. Cancer 135 (9) 2206-2214 [2014-11-01; online 2014-04-09]
Tissue Profiling
PubMed DOI Crossref
Histidine-rich glycoprotein uptake and turnover is mediated by mononuclear phagocytes.
Tugues S, Roche F, Noguer O, ..., Tolmachev V, Claesson-Welsh L
pmc
PLoS ONE 9 (9) e107483 [2014-09-22; online 2014-09-22]
Tissue Profiling
PubMed DOI Crossref
The prognostic value and therapeutic target role of stathmin-1 in urinary bladder cancer.
Hemdan T, Lindén M, Lind SB, ..., Malmström PU, Segersten U
pmc
Br. J. Cancer 111 (6) 1180-1187 [2014-09-09; online 2014-07-29]
Tissue Profiling [Collaborative]
PubMed DOI Crossref
An integrative analysis of the tumorigenic role of TAZ in human non-small cell lung cancer.
Noguchi S, Saito A, Horie M, ..., Micke P, Nagase T
Clin. Cancer Res. 20 (17) 4660-4672 [2014-09-01; online 2014-06-22]
Tissue Profiling
PubMed DOI Crossref
Analysis of candidate genes for lineage-specific expression changes in humans and primates.
Lindskog C, Kuhlwilm M, Davierwala A, ..., Pääbo S, Pontén F
J. Proteome Res. 13 (8) 3596-3606 [2014-08-01; online 2014-06-10]
Tissue Profiling
PubMed DOI Crossref
Decreased decorin expression in the tumor microenvironment.
Bozoky B, Savchenko A, Guven H, ..., Klein G, Szekely L
pmc
Cancer Med 3 (3) 485-491 [2014-06-00; online 2014-03-19]
Tissue Profiling
PubMed DOI Crossref
Garbage in, garbage out: a critical evaluation of strategies used for validation of immunohistochemical biomarkers.
O'Hurley G, Sjöstedt E, Rahman A, ..., Gallagher WM, Lindskog C
Mol Oncol 8 (4) 783-798 [2014-06-00; online 2014-04-15]
Tissue Profiling
PubMed DOI Crossref
WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism.
Sherwood V, Chaurasiya SK, Ekström EJ, ..., James P, Andersson T
pmc
Carcinogenesis 35 (4) 784-794 [2014-04-00; online 2013-12-03]
Tissue Profiling
PubMed DOI Crossref
Investigation of molecular alterations of AKT-3 in triple-negative breast cancer.
O'Hurley G, Daly E, O'Grady A, ..., Kay EW, Gallagher WM
Histopathology 64 (5) 660-670 [2014-04-00; online 2013-10-22]
Tissue Profiling
PubMed DOI Crossref
Antibody performance in western blot applications is context-dependent.
Algenäs C, Agaton C, Fagerberg L, ..., Ottosson Takanen J, Hober S
Biotechnol J 9 (3) 435-445 [2014-03-00; online 2014-01-10]
Cell Profiling Tissue Profiling
PubMed DOI Crossref
Subtyping of gliomas of various WHO grades by the application of immunohistochemistry.
Popova SN, Bergqvist M, Dimberg A, ..., Sooman L, Alafuzoff I
pmc
Histopathology 64 (3) 365-379 [2014-02-00; online 2014-01-15]
Tissue Profiling
PubMed DOI Crossref
Glioma-derived macrophage migration inhibitory factor (MIF) promotes mast cell recruitment in a STAT5-dependent manner.
Põlajeva J, Bergström T, Edqvist PH, ..., Forsberg Nilsson K, Tchougounova E
Mol Oncol 8 (1) 50-58 [2014-02-00; online 2013-10-05]
Tissue Profiling
PubMed DOI Crossref
A systematic analysis of commonly used antibodies in cancer diagnostics.
Gremel G, Bergman J, Djureinovic D, ..., Micke P, Pontén F
Histopathology 64 (2) 293-305 [2014-01-00; online 2013-12-18]
Tissue Profiling

Year 2013

PubMed DOI Crossref
In situ Protein Detection for Companion Diagnostics.
Gremel G, Grannas K, Sutton LA, Pontén F, Zieba A
pmc
Front Oncol 3 (-) 271 [2013-10-31; online 2013-10-31]
Tissue Profiling
PubMed DOI Crossref
Heart research advances using database search engines, Human Protein Atlas and the Sydney Heart Bank.
Li A, Estigoy C, Raftery M, ..., Lal S, Dos Remedios CG
Heart Lung Circ 22 (10) 819-826 [2013-10-00; online 2013-07-17]
Tissue Profiling
PubMed DOI Crossref
Tumour expression of bladder cancer-associated urinary proteins.
Lindén M, Segersten U, Runeson M, ..., Lind SB, Malmström PU
BJU Int. 112 (3) 407-415 [2013-08-00; online 2013-03-09]
Tissue Profiling
PubMed DOI Crossref
Novel signatures of cancer-associated fibroblasts.
Bozóky B, Savchenko A, Csermely P, ..., Székely L, Klein G
Int. J. Cancer 133 (2) 286-293 [2013-07-15; online 2013-01-16]
Tissue Profiling
PubMed DOI Crossref
Estrogen receptor β expression induces changes in the microRNA pool in human colon cancer cells.
Edvardsson K, Nguyen-Vu T, Kalasekar SM, ..., Gustafsson JÅ, Williams C
Carcinogenesis 34 (7) 1431-1441 [2013-07-00; online 2013-02-26]
Tissue Profiling
PubMed DOI Crossref
European H16N3 gull influenza virus attaches to the human respiratory tract and eye.
Lindskog C, Ellström P, Olsen B, ..., Kuiken T, Jourdain E
pmc
PLoS ONE 8 (4) e60757 [2013-04-08; online 2013-04-08]
Tissue Profiling
PubMed DOI Crossref
Integration of clinical data with a genome-scale metabolic model of the human adipocyte.
Mardinoglu A, Agren R, Kampf C, ..., Uhlen M, Nielsen J
pmc
Mol. Syst. Biol. 9 (-) 649 [2013-03-21; online 2013-03-21]
Tissue Profiling
PubMed DOI Crossref
STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer.
Peña C, Céspedes MV, Lindh MB, ..., Augsten M, Ostman A
Cancer Res. 73 (4) 1287-1297 [2013-02-15; online 2012-12-18]
Tissue Profiling

Year 2012

PubMed DOI Crossref
Transcription factor PROX1: its role in development and cancer.
Elsir T, Smits A, Lindström MS, Nistér M
Cancer Metastasis Rev. 31 (3-4) 793-805 [2012-12-00; online 2012-06-27]
Tissue Profiling
PubMed DOI Crossref
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, ..., Ostman A, Micke P
GEO
Int. J. Cancer 131 (10) 2264-2273 [2012-11-15; online 2012-03-07]
Array and Analysis Facility Tissue Profiling
PubMed DOI Crossref
TPX2 and AURKA promote 20q amplicon-driven colorectal adenoma to carcinoma progression.
Sillars-Hardebol AH, Carvalho B, Tijssen M, ..., Fijneman RJ, Meijer GA
Gut 61 (11) 1568-1575 [2012-11-00; online 2011-12-31]
Tissue Profiling
PubMed DOI Crossref
Consistent mutation status within histologically heterogeneous lung cancer lesions.
Mattsson JS, Imgenberg-Kreuz J, Edlund K, Botling J, Micke P
Histopathology 61 (4) 744-748 [2012-10-00; online 2012-03-31]
Tissue Profiling
PubMed DOI Crossref
Platelet-derived growth factor over-expression in retinal progenitors results in abnormal retinal vessel formation.
Edqvist PH, Niklasson M, Vidal-Sanz M, Hallböök F, Forsberg-Nilsson K
pmc
PLoS ONE 7 (8) e42488 [2012-08-03; online 2012-08-03]
Tissue Profiling
PubMed DOI Crossref
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
Lindskog C, Korsgren O, Pontén F, ..., Johansson L, Danielsson A
J Proteomics 75 (9) 2611-2620 [2012-05-17; online 2012-04-03]
Tissue Profiling
PubMed DOI Crossref
Scalable in situ hybridization on tissue arrays for validation of novel cancer and tissue-specific biomarkers.
Kiflemariam S, Andersson S, Asplund A, Pontén F, Sjöblom T
pmc
PLoS ONE 7 (3) e32927 [2012-03-08; online 2012-03-08]
Tissue Profiling
PubMed DOI Crossref
Antibody-based protein profiling of the human chromosome 21.
Uhlén M, Oksvold P, Älgenäs C, ..., Kondo T, Sivertsson Å
pmc
Mol. Cell Proteomics 11 (3) M111.013458 [2012-03-00; online 2011-11-02]
Cell Profiling Tissue Profiling
PubMed DOI Crossref
BCL2L1 has a functional role in colorectal cancer and its protein expression is associated with chromosome 20q gain.
Sillars-Hardebol AH, Carvalho B, Beliën JA, ..., Fijneman RJ, Meijer GA
J. Pathol. 226 (3) 442-450 [2012-02-00; online 2011-10-20]
Tissue Profiling

Year 2011

PubMed DOI Crossref
High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer.
Hjelm B, Brennan DJ, Zendehrokh N, ..., Jirström K, Uhlen M
Proteomics Clin Appl 5 (11-12) 624-635 [2011-12-00; online 2011-10-01]
Tissue Profiling
PubMed DOI Crossref
Large-scale protein profiling in human cell lines using antibody-based proteomics.
Fagerberg L, Strömberg S, El-Obeid A, ..., Ponten F, Asplund A
J. Proteome Res. 10 (9) 4066-4075 [2011-09-02; online 2011-07-06]
Tissue Profiling
PubMed DOI Crossref
Functional and prognostic relevance of the homeobox protein MSX2 in malignant melanoma.
Gremel G, Ryan D, Rafferty M, ..., Ponten F, Gallagher WM
pmc
Br. J. Cancer 105 (4) 565-574 [2011-08-09; online 2011-07-07]
Tissue Profiling
PubMed
RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer.
Ehlén Å, Nodin B, Rexhepaj E, ..., Brennan DJ, Jirström K
pmc
Transl Oncol 4 (4) 212-221 [2011-08-00; online 2011-08-01]
Tissue Profiling
PubMed DOI Crossref
SATB2 in combination with cytokeratin 20 identifies over 95% of all colorectal carcinomas.
Magnusson K, de Wit M, Brennan DJ, ..., Jirström K, Pontén F
Am. J. Surg. Pathol. 35 (7) 937-948 [2011-07-00; online 2011-06-17]
Cell Profiling Tissue Profiling
PubMed DOI Crossref
Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer.
Wallin U, Glimelius B, Jirström K, ..., Påhlman L, Birgisson H
pmc
Br. J. Cancer 104 (10) 1619-1627 [2011-05-10; online 2011-04-07]
Tissue Profiling
PubMed DOI Crossref
Diagnostic biomarkers of prostate cancer.
Häggarth L, Hägglöf C, Jaraj SJ, ..., Ostman A, Egevad L
Scand. J. Urol. Nephrol. 45 (1) 60-67 [2011-02-00; online 2010-11-03]
Tissue Profiling
PubMed DOI Crossref
GAD1 is a biomarker for benign and malignant prostatic tissue.
Jaraj SJ, Augsten M, Häggarth L, ..., Ostman A, Egevad L
Scand. J. Urol. Nephrol. 45 (1) 39-45 [2011-02-00; online 2010-11-26]
Tissue Profiling

Year 2010

PubMed DOI Crossref
SOX10 expression in superficial spreading and nodular malignant melanomas.
Agnarsdóttir M, Sooman L, Bolander A, ..., Uhlen M, Hedstrand H
Melanoma Res. 20 (6) 468-478 [2010-12-00; online 2010-10-05]
Tissue Profiling
PubMed DOI Crossref
Topoisomerase I amplification in melanoma is associated with more advanced tumours and poor prognosis.
Ryan D, Rafferty M, Hegarty S, ..., Dervan PA, Gallagher WM
Pigment Cell Melanoma Res 23 (4) 542-553 [2010-08-00; online 2010-05-15]
Tissue Profiling
PubMed
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Lindskog C, Asplund A, Engkvist M, ..., Korsgren O, Ponten F
Discov Med 9 (49) 565-578 [2010-06-00; online 2010-07-01]
Tissue Profiling
PubMed DOI Crossref
Tumour-specific HMG-CoAR is an independent predictor of recurrence free survival in epithelial ovarian cancer.
Brennan DJ, Brändstedt J, Rexhepaj E, ..., O'Herlihy C, Jirstrom K
pmc
BMC Cancer 10 (-) 125 [2010-04-01; online 2010-04-01]
Tissue Profiling
PubMed DOI Crossref
The impact of tissue fixatives on morphology and antibody-based protein profiling in tissues and cells.
Paavilainen L, Edvinsson A, Asplund A, ..., Pontén F, Wester K
pmc
J. Histochem. Cytochem. 58 (3) 237-246 [2010-03-00; online 2009-11-11]
Tissue Profiling
DOI Crossref
Tissue-Specific Protein Expression in Human Cells, Tissues and Organs
Gry M, Oksvold P, Pontén F, Uhlén M
JPB 03 (10) - [2010-00-00; online 2010-00-00]
Tissue Profiling