Array and Analysis Facility

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Regional facility of national interest between 2013-2016.

Primary: Shown in the list of current labels, if end date is not specified.

Started: 2013

Ended: 2016

Year 2016

PubMed DOI Crossref
Rawcopy: Improved copy number analysis with Affymetrix arrays.
Mayrhofer M, Viklund B, Isaksson A
Sci Rep 6 (-) 36158 [2016-10-31; online 2016-10-31]
Array and Analysis Facility [Technology development]
PubMed DOI Crossref
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma.
Roy A, Femel J, Huijbers EJ, ..., Olsson AK, Åbrink M
PLoS ONE 11 (5) e0156151 [2016-05-25; online 2016-05-25]
Array and Analysis Facility [Service]
PubMed DOI Crossref
Using an Inbred Horse Breed in a High Density Genome-Wide Scan for Genetic Risk Factors of Insect Bite Hypersensitivity (IBH).
Velie BD, Shrestha M, Franҫois L, ..., Buys N, Lindgren G
PLoS ONE 11 (4) e0152966 [2016-04-12; online 2016-04-12]
Array and Analysis Facility [Service]
PubMed DOI Crossref
Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis.
Walther C, Mayrhofer M, Nilsson J, ..., Gisselsson D, Mertens F
Genes Chromosomes Cancer 55 (1) 3-15 [2016-01-00; online 2015-10-20]
Array and Analysis Facility [Collaborative]

Year 2015

PubMed DOI Crossref
Spatiotemporal Heterogeneity Characterizes the Genetic Landscape of Pheochromocytoma and Defines Early Events in Tumorigenesis.
Crona J, Backman S, Maharjan R, ..., Hellman P, Björklund P
Clin. Cancer Res. 21 (19) 4451-4460 [2015-10-01; online 2015-05-21]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed DOI Crossref
The use of gene arrays and corresponding connectivity mapping (Cmap) to identify novel anti-ageing ingredients.
Gillbro JM, Merinville E, Olsson M, ..., Visdal-Johnsen L, Mavon A
Int J Cosmet Sci 37 Suppl 1 (-) 9-14 [2015-10-00; online 2015-06-27]
Array and Analysis Facility
PubMed DOI Crossref
The Human Glioblastoma Cell Culture Resource: Validated Cell Models Representing All Molecular Subtypes.
Xie Y, Bergström T, Jiang Y, ..., Forsberg-Nilsson K, Uhrbom L
EBioMedicine 2 (10) 1351-1363 [2015-10-00; online 2015-08-15]
Array and Analysis Facility
PubMed DOI Crossref
Distinguishing Mast Cell Progenitors from Mature Mast Cells in Mice.
Dahlin JS, Ding Z, Hallgren J
Stem Cells Dev. 24 (14) 1703-1711 [2015-07-15; online 2015-03-10]
Array and Analysis Facility
PubMed DOI Crossref
Functional loss of IκBε leads to NF-κB deregulation in aggressive chronic lymphocytic leukemia.
Mansouri L, Sutton LA, Ljungström V, ..., Nilsson M, Rosenquist R
J. Exp. Med. 212 (6) 833-843 [2015-06-01; online 2015-05-18]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed
Differential Gene Regulation in Fibroblasts in Co-culture with Keratinocytes and Head and Neck SCC Cells.
Hakelius M, Saiepour D, Göransson H, ..., Gerdin B, Nowinski D
Anticancer Res. 35 (6) 3253-3265 [2015-06-00; online 2015-05-31]
Array and Analysis Facility
PubMed DOI Crossref
Site-specific programming of the host epithelial transcriptome by the gut microbiota.
Sommer F, Nookaew I, Sommer N, Fogelstrand P, Bäckhed F
Genome Biol. 16 (-) 62 [2015-03-28; online 2015-03-28]
Array and Analysis Facility Bioinformatics Support and Infrastructure Bioinformatics Support, Infrastructure and Training
PubMed DOI Crossref
Microsatellite instability and mutations in BRAF and KRAS are significant predictors of disseminated disease in colon cancer.
Birgisson H, Edlund K, Wallin U, ..., Glimelius B, Sundström M
BMC Cancer 15 (-) 125 [2015-03-14; online 2015-03-14]
Array and Analysis Facility
PubMed DOI Crossref
Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer.
Mengelbier LH, Karlsson J, Lindgren D, ..., Mayrhofer M, Gisselsson D
Nat Commun 6 (-) 6125 [2015-01-27; online 2015-01-27]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure

Year 2014

PubMed DOI Crossref
1p36 deletion is a marker for tumour dissemination in microsatellite stable stage II-III colon cancer.
Mayrhofer M, Kultima HG, Birgisson H, ..., Glimelius B, Isaksson A
BMC Cancer 14 (-) 872 [2014-11-24; online 2014-11-24]
Array and Analysis Facility

Year 2013

PubMed DOI Crossref
Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines.
Sooman L, Ekman S, Andersson C, ..., Lennartsson J, Gullbo J
Cancer Chemother. Pharmacol. 72 (2) 329-340 [2013-08-00; online 2013-06-06]
Array and Analysis Facility
PubMed DOI Crossref
Behavioural and Brain Gene Expression Profiling in Pigs during Tail Biting Outbreaks - Evidence of a Tail Biting Resistant Phenotype.
Brunberg E, Jensen P, Isaksson A, Keeling LJ
PLoS ONE 8 (6) e66513 [2013-06-18; online 2013-06-18]
Array and Analysis Facility
PubMed DOI Crossref
Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system.
Felth J, Lesiak-Mieczkowska K, D'Arcy P, ..., Fryknäs M, Rickardson L
Invest New Drugs 31 (3) 587-598 [2013-06-00; online 2012-11-28]
Array and Analysis Facility
PubMed DOI Crossref
Patchwork: allele-specific copy number analysis of whole-genome sequenced tumor tissue.
Mayrhofer M, DiLorenzo S, Isaksson A
Genome Biol. 14 (3) R24 [2013-03-25; online 2013-03-25]
Array and Analysis Facility
PubMed DOI Crossref
Brain gene expression differences are associated with abnormal tail biting behavior in pigs.
Brunberg E, Jensen P, Isaksson A, Keeling LJ
Genes Brain Behav. 12 (2) 275-281 [2013-03-00; online 2012-11-14]
Array and Analysis Facility
PubMed DOI Crossref
A modified Glenn shunt improves haemodynamics in acute right ventricular failure in an experimental model.
Vikholm P, Schiller P, Johansson J, Hellgren L
Eur J Cardiothorac Surg 43 (3) 612-618 [2013-03-00; online 2012-07-05]
Array and Analysis Facility
PubMed DOI Crossref
Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation.
Botling J, Edlund K, Lohr M, ..., Hengstler JG, Micke P
Clin. Cancer Res. 19 (1) 194-204 [2013-01-01; online 2012-10-02]
Array and Analysis Facility Tissue Profiling
PubMed DOI Crossref
450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments.
Cahill N, Bergh AC, Kanduri M, ..., Rosén A, Rosenquist R
Leukemia 27 (1) 150-158 [2013-01-00; online 2012-08-28]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure

Year 2012

PubMed DOI Crossref
Distinct transcriptional control in major immunogenetic subsets of chronic lymphocytic leukemia exhibiting subset-biased global DNA methylation profiles.
Kanduri M, Marincevic M, Halldórsdóttir AM, ..., Stamatopoulos K, Rosenquist R
Epigenetics 7 (12) 1435-1442 [2012-12-01; online 2012-11-17]
Array and Analysis Facility
PubMed DOI Crossref
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, ..., Ostman A, Micke P
Int. J. Cancer 131 (10) 2264-2273 [2012-11-15; online 2012-03-07]
Array and Analysis Facility Tissue Profiling
PubMed DOI Crossref
Transcriptional profiling of human glioblastoma vessels indicates a key role of VEGF-A and TGFβ2 in vascular abnormalization.
Dieterich LC, Mellberg S, Langenkamp E, ..., Alafuzoff I, Dimberg A
J. Pathol. 228 (3) 378-390 [2012-11-00; online 2012-07-13]
Array and Analysis Facility Tissue Profiling
PubMed DOI Crossref
Role of sepsis in the development of limb muscle weakness in a porcine intensive care unit model.
Aare S, Radell P, Eriksson LI, ..., Hoffman EP, Larsson L
Physiol. Genomics 44 (18) 865-877 [2012-09-18; online 2012-08-02]
Array and Analysis Facility
PubMed DOI Crossref
Loss-of-heterozygosity on chromosome 19q in early-stage serous ovarian cancer is associated with recurrent disease.
Skirnisdottir I, Mayrhofer M, Rydåker M, Akerud H, Isaksson A
BMC Cancer 12 (-) 407 [2012-09-12; online 2012-09-12]
Array and Analysis Facility
PubMed DOI Crossref
Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs.
Ahlberg V, Lövgren Bengtsson K, Wallgren P, Fossum C
Dev. Comp. Immunol. 38 (1) 17-26 [2012-09-00; online 2012-03-20]
Array and Analysis Facility
PubMed DOI Crossref
Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system.
Karlsson H, Fryknäs M, Larsson R, Nygren P
Exp. Cell Res. 318 (13) 1577-1585 [2012-08-01; online 2012-04-11]
Array and Analysis Facility
PubMed DOI Crossref
Next generation RNA-sequencing in prognostic subsets of chronic lymphocytic leukemia.
Mansouri L, Gunnarsson R, Sutton LA, ..., Gyllensten U, Rosenquist R
Am. J. Hematol. 87 (7) 737-740 [2012-07-00; online 2012-06-03]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure
DOI Crossref
1012 Synergistic Effects of PI3K or P38 MAPK Inhibition in Combination With Vandetanib Treatment in Glioblastoma Cells
Sooman L, Ekman S, Andersson C, ..., Lennartsson J, Gullbo J
European Journal of Cancer 48 (-) S244 [2012-07-00; online 2012-07-00]
Array and Analysis Facility
PubMed DOI Crossref
Digital gene expression profiling of primary acute lymphoblastic leukemia cells.
Nordlund J, Kiialainen A, Karlberg O, ..., Lönnerholm G, Syvänen AC
Leukemia 26 (6) 1218-1227 [2012-06-00; online 2011-12-16]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed DOI Crossref
Accelerated proliferation and differential global gene expression in pancreatic islets of five-week-old heterozygous Men1 mice: Men1 is a haploinsufficient suppressor.
Lejonklou MH, Barbu A, Stålberg P, Skogseid B
Endocrinology 153 (6) 2588-2598 [2012-06-00; online 2012-04-12]
Array and Analysis Facility
PubMed DOI Crossref
A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin κ C as a compatible prognostic marker in human solid tumors.
Schmidt M, Hellwig B, Hammad S, ..., Rahnenführer J, Hengstler JG
Clin. Cancer Res. 18 (9) 2695-2703 [2012-05-01; online 2012-02-22]
Array and Analysis Facility
PubMed DOI Crossref
Transgenerational effects of early experience on behavioral, hormonal and gene expression responses to acute stress in the precocial chicken.
Goerlich VC, Nätt D, Elfwing M, Macdonald B, Jensen P
Horm Behav 61 (5) 711-718 [2012-05-00; online 2012-04-03]
Array and Analysis Facility
PubMed DOI Crossref
Tumor-mast cell interactions: induction of pro-tumorigenic genes and anti-tumorigenic 4-1BB in MCs in response to Lewis Lung Carcinoma.
Wensman H, Kamgari N, Johansson A, ..., Rönnberg E, Pejler G
Mol. Immunol. 50 (4) 210-219 [2012-04-00; online 2012-02-22]
Array and Analysis Facility
PubMed DOI Crossref
Mantle cell lymphoma displays a homogenous methylation profile: a comparative analysis with chronic lymphocytic leukemia.
Halldórsdóttir AM, Kanduri M, Marincevic M, ..., Ehrencrona H, Rosenquist R
Am. J. Hematol. 87 (4) 361-367 [2012-04-00; online 2012-03-01]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed DOI Crossref
The transcriptome of the adenovirus infected cell.
Zhao H, Dahlö M, Isaksson A, Syvänen AC, Pettersson U
Virology 424 (2) 115-128 [2012-03-15; online 2012-01-13]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed DOI Crossref
Microarray profiling of diaphyseal bone of rats suffering from hypervitaminosis A.
Lind T, Hu L, Lind PM, ..., Jacobson A, Melhus H
Calcif. Tissue Int. 90 (3) 219-229 [2012-03-00; online 2012-01-05]
Array and Analysis Facility
PubMed DOI Crossref
Heritable genome-wide variation of gene expression and promoter methylation between wild and domesticated chickens.
Nätt D, Rubin CJ, Wright D, ..., Andersson L, Jensen P
BMC Genomics 13 (-) 59 [2012-02-04; online 2012-02-04]
Array and Analysis Facility
PubMed DOI Crossref
Lymphoblastoid cell line with B1 cell characteristics established from a chronic lymphocytic leukemia clone by in vitro EBV infection.
Rosén A, Bergh AC, Gogok P, ..., Rosenquist R, Klein E
Oncoimmunology 1 (1) 18-27 [2012-01-01; online 2012-06-22]
Array and Analysis Facility

Year 2011

PubMed DOI Crossref
Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model.
Aare S, Ochala J, Norman HS, ..., Hoffman EP, Larsson L
Physiol. Genomics 43 (24) 1334-1350 [2011-12-16; online 2011-10-20]
Array and Analysis Facility
PubMed DOI Crossref
Muscle wasting and the temporal gene expression pattern in a novel rat intensive care unit model.
Llano-Diez M, Gustafson AM, Olsson C, Goransson H, Larsson L
BMC Genomics 12 (-) 602 [2011-12-13; online 2011-12-13]
Array and Analysis Facility
PubMed DOI Crossref
Inhibition of proteasome deubiquitinating activity as a new cancer therapy.
D'Arcy P, Brnjic S, Olofsson MH, ..., Larsson R, Linder S
Nat. Med. 17 (12) 1636-1640 [2011-11-06; online 2011-11-06]
Array and Analysis Facility
PubMed DOI Crossref
Gene copy number aberrations are associated with survival in histologic subgroups of non-small cell lung cancer.
Micke P, Edlund K, Holmberg L, ..., Isaksson A, Botling J
J Thorac Oncol 6 (11) 1833-1840 [2011-11-00; online 2011-10-21]
Array and Analysis Facility
PubMed DOI Crossref
Allele-specific copy number analysis of tumor samples with aneuploidy and tumor heterogeneity.
Rasmussen M, Sundström M, Göransson Kultima H, ..., Glimelius B, Isaksson A
Genome Biol. 12 (10) R108 [2011-10-24; online 2011-10-24]
Array and Analysis Facility
PubMed DOI Crossref
Genomic and clinical characteristics of six patients with partially overlapping interstitial deletions at 10p12p11.
Wentzel C, Rajcan-Separovic E, Ruivenkamp CA, ..., Giurgea I, Thuresson AC
Eur. J. Hum. Genet. 19 (9) 959-964 [2011-09-00; online 2011-04-28]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure
PubMed DOI Crossref
Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia.
Gunnarsson R, Mansouri L, Isaksson A, ..., Juliusson G, Rosenquist R
Haematologica 96 (8) 1161-1169 [2011-08-00; online 2011-05-07]
Array and Analysis Facility NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
Prostasomal DNA characterization and transfer into human sperm.
Ronquist GK, Larsson A, Ronquist G, ..., Carlsson L, Stavreus-Evers A
Mol. Reprod. Dev. 78 (7) 467-476 [2011-07-00; online 2011-06-04]
Array and Analysis Facility
PubMed DOI Crossref
Feather pecking behavior in laying hens: hypothalamic gene expression in birds performing and receiving pecks.
Brunberg E, Jensen P, Isaksson A, Keeling L
Poult. Sci. 90 (6) 1145-1152 [2011-06-00; online 2011-05-21]
Array and Analysis Facility
PubMed DOI Crossref
Experimental evidence supports a sex-specific selective sieve in mitochondrial genome evolution.
Innocenti P, Morrow EH, Dowling DK
Science 332 (6031) 845-848 [2011-05-13; online 2011-05-14]
Array and Analysis Facility
PubMed DOI Crossref
The 12q14 microdeletion syndrome: six new cases confirming the role of HMGA2 in growth.
Lynch SA, Foulds N, Thuresson AC, ..., Ennis S, Sharkey F
Eur. J. Hum. Genet. 19 (5) 534-539 [2011-05-00; online 2011-01-27]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure
PubMed DOI Crossref
High-resolution genomic screening in mantle cell lymphoma--specific changes correlate with genomic complexity, the proliferation signature and survival.
Halldórsdóttir AM, Sander B, Göransson H, ..., Rosenquist R, Ehrencrona H
Genes Chromosomes Cancer 50 (2) 113-121 [2011-02-00; online 2010-12-01]
Array and Analysis Facility NGI Stockholm (Genomics Applications) NGI Stockholm (Genomics Production) National Genomics Infrastructure
PubMed DOI Crossref
Targeted resequencing of candidate genes using selector probes.
Johansson H, Isaksson M, Sörqvist EF, ..., Ericsson O, Nilsson M
Nucleic Acids Res. 39 (2) e8 [2011-01-00; online 2010-11-08]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure

Year 2010

PubMed DOI Crossref
Distinct gene expression profiles in subsets of chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors.
Marincevic M, Mansouri M, Kanduri M, ..., Stamatopoulos K, Rosenquist R
Haematologica 95 (12) 2072-2079 [2010-12-00; online 2010-08-31]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure
PubMed DOI Crossref
High-density screening reveals a different spectrum of genomic aberrations in chronic lymphocytic leukemia patients with 'stereotyped' IGHV3-21 and IGHV4-34 B-cell receptors.
Marincevic M, Cahill N, Gunnarsson R, ..., Stamatopoulos K, Rosenquist R
Haematologica 95 (9) 1519-1525 [2010-09-00; online 2010-04-28]
Array and Analysis Facility
PubMed DOI Crossref
Ontogenetic complexity of sexual dimorphism and sex-specific selection.
Mank JE, Nam K, Brunström B, Ellegren H
Mol. Biol. Evol. 27 (7) 1570-1578 [2010-07-00; online 2010-02-10]
Array and Analysis Facility
PubMed DOI Crossref
Characterization of the RNA content of chromatin.
Mondal T, Rasmussen M, Pandey GK, Isaksson A, Kanduri C
Genome Res. 20 (7) 899-907 [2010-07-00; online 2010-04-21]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed DOI Crossref
Interstitial Deletions at 6q14.1-q15 Associated with Obesity, Developmental Delay and a Distinct Clinical Phenotype.
Wentzel C, Lynch SA, Stattin EL, ..., Annerén G, Thuresson AC
Mol Syndromol 1 (2) 75-81 [2010-06-09; online 2010-06-09]
Array and Analysis Facility NGI Uppsala (Uppsala Genome Center) National Genomics Infrastructure
PubMed DOI Crossref
Improving Bayesian credibility intervals for classifier error rates using maximum entropy empirical priors.
Gustafsson MG, Wallman M, Wickenberg Bolin U, ..., Andersson CR, Isaksson A
Artif Intell Med 49 (2) 93-104 [2010-06-00; online 2010-03-30]
Array and Analysis Facility
PubMed
Alpha terpineol: a potential anticancer agent which acts through suppressing NF-kappaB signalling.
Hassan SB, Gali-Muhtasib H, Göransson H, Larsson R
Anticancer Res. 30 (6) 1911-1919 [2010-06-00; online 2010-07-24]
Array and Analysis Facility
PubMed DOI Crossref
The sexually antagonistic genes of Drosophila melanogaster.
Innocenti P, Morrow EH
PLoS Biol. 8 (3) e1000335 [2010-03-16; online 2010-03-16]
Array and Analysis Facility
PubMed DOI Crossref
Appearance of Cxcl10-expressing cell clusters is common for traumatic brain injury and neurodegenerative disorders.
Israelsson C, Bengtsson H, Lobell A, ..., Hillered L, Ebendal T
Eur. J. Neurosci. 31 (5) 852-863 [2010-03-00; online 2010-04-09]
Array and Analysis Facility
PubMed DOI Crossref
Infection of mast cells with live streptococci causes a toll-like receptor 2- and cell-cell contact-dependent cytokine and chemokine response.
Rönnberg E, Guss B, Pejler G
Infect. Immun. 78 (2) 854-864 [2010-02-00; online 2009-11-26]
Array and Analysis Facility
PubMed DOI Crossref
Differential genome-wide array-based methylation profiles in prognostic subsets of chronic lymphocytic leukemia.
Kanduri M, Cahill N, Göransson H, ..., Isaksson A, Rosenquist R
Blood 115 (2) 296-305 [2010-01-14; online 2009-11-10]
Array and Analysis Facility NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure
PubMed DOI Crossref
Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients.
Gunnarsson R, Isaksson A, Mansouri M, ..., Juliusson G, Rosenquist R
Leukemia 24 (1) 211-215 [2010-01-00; online 2009-09-11]
Array and Analysis Facility
PubMed DOI Crossref
Characterization of the cytotoxic properties of the benzimidazole fungicides, benomyl and carbendazim, in human tumour cell lines and primary cultures of patient tumour cells.
Laryea D, Gullbo J, Isaksson A, Larsson R, Nygren P
Anticancer Drugs 21 (1) 33-42 [2010-01-00; online 2009-09-30]
Array and Analysis Facility
SciLifeLab Data Centre
Publications 9.5.1