Chen X

Precise mapping of single-stranded DNA breaks by sequence-templated erroneous DNA polymerase end-labelling.

Wenson L, Heldin J, Martin M, ..., Spjuth O, Söderberg O

Nat Commun 16 (1) 7130 [2025-08-04; online 2025-08-04]

Bioinformatics Support, Infrastructure and Training [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service]

Identification of a small molecule targeting EPLIN as a novel strategy for the treatment of pediatric neuroblastoma and medulloblastoma.

Lindell E, Guo J, Zhao M, ..., Sjöblom T, Zhang X

Cell Death Dis 16 (1) 554 [2025-07-23; online 2025-07-23]

NGI Single cell [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Dormant SOX9-positive cells facilitate MYC-driven recurrence of medulloblastoma.

Borgenvik A, Holmberg KO, Bolin S, ..., Weishaupt H, Swartling FJ

Cancer Res. - (-) - [2022-10-11; online 2022-10-11]

Bioinformatics Support for Computational Resources [Service] NGI Single cell [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival.

Lu X, Maturi NP, Jarvius M, ..., Uhrbom L, Chen X

Nat Commun 13 (1) 2236 [2022-04-25; online 2022-04-25]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Single-Cell Analysis Reveals Major Histocompatibility Complex II‒Expressing Keratinocytes in Pressure Ulcers with Worse Healing Outcomes.

Li D, Cheng S, Pei Y, ..., Deng Q, Xu Landén N

J. Invest. Dermatol. - (-) - [2021-09-16; online 2021-09-16]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]