Dantuma NP

Mitochondria serve as a holdout compartment for aggregation-prone proteins hindering efficient degradation.

Gierisch ME, Barchi E, Marogna M, ..., Salomons FA, Dantuma NP

Nat Commun 17 (1) - [2026-05-07; online 2026-05-07]

CRISPR Functional Genomics [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]

Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy

Giovannucci TA, Salomons FA, Stoy H, ..., Vallin M, Dantuma NP

Autophagy 18 (7) 1486-1502 [2022-07-03; online 2021-11-05]

Chemical Biology Consortium Sweden [Collaborative]

Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy.

Giovannucci TA, Salomons FA, Stoy H, ..., Vallin M, Dantuma NP

Autophagy 18 (7) 1486-1502 [2022-07-00; online 2021-11-05]

Chemical Biology Consortium Sweden [Collaborative]

Inhibition of the ubiquitin-proteasome system by an NQO1-activatable compound.

Giovannucci TA, Salomons FA, Haraldsson M, ..., Johnsen JI, Dantuma NP

Cell Death Dis 12 (10) 914 [2021-10-06; online 2021-10-06]

CRISPR Functional Genomics [Service] Chemical Biology Consortium Sweden [Collaborative] Global Proteomics and Proteogenomics [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service]