Sanyal S

Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis.

Majumdar S, Emmerich A, Krakovka S, ..., Svärd SG, Sanyal S

Nucleic Acids Res. 51 (7) 3436-3451 [2023-04-24; online 2023-03-14]

Cryo-EM [Service] Global Proteomics and Proteogenomics [Service]

Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.

Parajuli NP, Emmerich A, Mandava CS, Pavlov MY, Sanyal S

Nat Commun 14 (1) 918 [2023-02-17; online 2023-02-17]

Cryo-EM [Service]

Inhibition of translation termination by small molecules targeting ribosomal release factors.

Ge X, Oliveira A, Hjort K, ..., Sanyal S, Åqvist J

Sci Rep 9 (1) 15424 [2019-10-28; online 2019-10-28]

Bioinformatics Compute and Storage [Service] Drug Discovery and Development (DDD) [Service]