Obi I

Mechanistic insights into PCBP1-driven unfolding of selected i-motif DNA at G1/S checkpoint.

Sengupta P, Gillet N, Obi I, Sabouri N

Nat Commun 17 (1) 1149 [2026-02-02; online 2026-02-02]

Swedish NMR Centre [Service]

CRISPR-Cas9 targeting of G-Quadruplex DNA in ADH1 promoter highlights its role in transcriptome and metabolome regulation.

Obi I, Sengupta P, Sabouri N

Nucleic Acids Res. 53 (17) - [2025-09-05; online 2025-09-18]

Swedish Metabolomics Centre [Service] Swedish NMR Centre [Service]

A new G-quadruplex-specific photosensitizer inducing genome instability in cancer cells by triggering oxidative DNA damage and impeding replication fork progression.

Deiana M, Andrés Castán JM, Josse P, ..., Cabanetos C, Sabouri N

Nucleic Acids Res. 51 (12) 6264-6285 [2023-07-07; online 2023-05-16]

Swedish NMR Centre [Service]

A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA.

Deiana M, Chand K, Jamroskovic J, ..., Chorell E, Sabouri N

Nanoscale 12 (24) 12950-12957 [2020-06-25; online 2020-06-12]

Swedish NMR Centre [Service]

A Light-up Logic Platform for Selective Recognition of Parallel G-Quadruplex Structures via Disaggregation-Induced Emission.

Deiana M, Chand K, Jamroskovic J, ..., Chorell E, Sabouri N

Angew. Chem. Int. Ed. Engl. 59 (2) 896-902 [2020-01-07; online 2019-11-22]

Integrated Microscopy Technologies Umeå [Service]