Swedish Metabolomics Centre

Pisolithus microcarpus isolates with contrasting abilities to colonise Eucalyptus grandis exhibit significant differences in metabolic signalling.

Vishwakarma K, Buckley S, Plett JM, ..., Jämtgård S, Plett KL

Fungal Biol 128 (7) 2157-2166 [2024-11-00; online 2024-09-10]

Modification of xylan in secondary walls alters cell wall biosynthesis and wood formation programs and improves saccharification.

Sivan P, Urbancsok J, Donev EN, ..., Vilaplana F, Mellerowicz EJ

Plant Biotechnol. J. - (-) - [2024-10-22; online 2024-10-22]

Cryo-EM [Service] Swedish Metabolomics Centre [Service]

Limosilactobacillus reuteri DSM 17938 Produce Bioactive Components during Formulation in Sucrose.

Ermann Lundberg L, Mata Forsberg M, Lemanczyk J, ..., Roos S, Håkansson S

Microorganisms 12 (10) - [2024-10-12; online 2024-10-12]

Multi-omics profiling to identify early plasma biomarkers in pre-diagnostic pancreatic ductal adenocarcinoma: a nested case-control study.

Borgmästars E, Ulfenborg B, Johansson M, ..., Lubovac-Pilav Z, Sund M

Transl Oncol 48 (-) 102059 [2024-10-00; online 2024-07-16]

Affinity Proteomics Uppsala [Service] Swedish Metabolomics Centre [Service]

Comparative proteomic analyses of potato leaves from field-grown plants grown under extremely long days.

Resjö S, Willforss J, Large A, ..., Levander F, Andreasson E

Plant Physiol Biochem 215 (-) 109032 [2024-10-00; online 2024-08-10]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Metabolic Phenotyping from Whole-Blood Responses to a Standardized Exercise Test May Discriminate for Physiological, Performance, and Illness Outcomes: A Pilot Study in Highly-Trained Cross-Country Skiers.

Karlsson Ø, Govus AD, McGawley K, Hanstock HG

Sports Med Open 10 (1) 99 [2024-09-18; online 2024-09-18]

Blood based metabolic markers of glioma from pre-diagnosis to surgery.

Löding S, Antti H, Sjöberg RL, Melin B, Björkblom B

Sci Rep 14 (1) 20680 [2024-09-05; online 2024-09-05]

Oral nicotinamide provides robust, dose-dependent structural and metabolic neuroprotection of retinal ganglion cells in experimental glaucoma.

Cimaglia G, Tribble JR, Votruba M, Williams PA, Morgan JE

Acta Neuropathol Commun 12 (1) 137 [2024-08-23; online 2024-08-23]

Obscurity of chlorophyll tails - Is chlorophyll with farnesyl tail incorporated into PSII complexes?

Graça AT, Lihavainen J, Hussein R, Schröder WP

Physiol Plantarum 176 (4) e14428 [2024-07-10; online 2024-07-10]

Reduced adipocyte glutaminase activity promotes energy expenditure and metabolic health.

Lecoutre S, Maqdasy S, Rizo-Roca D, ..., Mejhert N, Rydén M

Nat Metab 6 (7) 1329-1346 [2024-07-00; online 2024-07-15]

Myofiber-specific lipidomics unveil differential contributions to insulin sensitivity in individuals of African and European ancestry.

Eurén T, Gower B, Steneberg P, ..., Edlund H, Chorell E

Heliyon 10 (12) e32456 [2024-06-30; online 2024-06-05]

LAPTM4B counteracts ferroptosis via suppressing the ubiquitin-proteasome degradation of SLC7A11 in non-small cell lung cancer.

Yan R, Liu D, Guo H, ..., Blom T, Zhou K

Cell Death Dis 15 (6) 436 [2024-06-20; online 2024-06-20]

Metabolomics profiling reveals the detoxification and tolerance behavior of two bread wheat (Triticum aestivum L.) varieties under arsenate stress.

Saeed M, Masood Quraishi U, Mustafa G, ..., Greger M, Naseem Malik R

Food Chem 443 (-) 138612 [2024-06-15; online 2024-01-28]

Towards identification of new genetic determinants for post-weaning diarrhea in piglets.

Ibragimov E, Eriksen EØ, Nielsen JP, ..., Fredholm M, Karlskov-Mortensen P

Anim Genet 55 (3) 387-395 [2024-06-00; online 2024-02-11]

Overexpression of the plastidial pseudo-protease AtFtsHi3 enhances drought tolerance while sustaining plant growth.

Mishra LS, Cook SD, Kushwah S, ..., Libby E, Funk C

Physiol Plantarum 176 (3) e14370 [2024-05-31; online 2024-05-31]

The Metabolomic Profile of Microscopic Colitis Is Affected by Smoking but Not Histopathological Diagnosis, Clinical Course, Symptoms, or Treatment.

Ström A, Stenlund H, Ohlsson B

Metabolites 14 (6) - [2024-05-27; online 2024-05-27]

In situ seasonal patterns of root auxin concentrations and meristem length in an arctic sedge.

Blume-Werry G, Semenchuk P, Ljung K, ..., Olofsson J, Brunoni F

New Phytol. 242 (3) 988-999 [2024-05-00; online 2024-02-20]

Impact of the neurotoxin β-N-methylamino-L-alanine on the diatom Thalassiosira pseudonana using metabolomics.

Kim SY, Rasmussen U, Rydberg S

Mar Pollut Bull 202 (-) 116299 [2024-05-00; online 2024-04-06]

Metabolomics for early pancreatic cancer detection in plasma samples from a Swedish prospective population-based biobank.

Borgmästars E, Jacobson S, Simm M, ..., Franklin O, Sund M

J Gastrointest Oncol 15 (2) 755-767 [2024-04-30; online 2024-04-28]

Profiling of 1-aminocyclopropane-1-carboxylic acid and selected phytohormones in Arabidopsis using liquid chromatography-tandem mass spectrometry.

Karady M, Hladík P, Cermanová K, ..., Ljung K, Novák O

Plant Methods 20 (1) 41 [2024-03-16; online 2024-03-16]

Influence of divalent cations on the extraction of organic acids in coffee determined by GC-MS and NMR.

Bratthäll T, Figueira J, Nording ML

Heliyon 10 (5) e26625 [2024-03-15; online 2024-02-17]

Swedish Metabolomics Centre [Service] Swedish NMR Centre [Collaborative]

Oxylipin profiling by LC-ESI-MS/MS in canine serum and plasma to investigate ovulation-specific changes.

Ramström M, Holst BS, Lindberg R, Nording ML

Prostaglandins Other Lipid Mediat. 170 (-) 106790 [2024-02-00; online 2023-10-31]

Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise – A systems biology approach

Reitzner SM, Emanuelsson EB, Arif M, ..., Chapman MA, Sundberg CJ

Mol Metab 79 (-) 101857 [2024-01-00; online 2024-01-00]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes

Rönn T, Ofori JK, Perfilyev A, ..., Bacos K, Ling C

Nat Commun 14 (1) 8040 [2023-12-12; online 2023-12-12]

Fluorescence-activated multi-organelle mapping of subcellular plant hormone distribution.

Skalický V, Antoniadi I, Pěnčík A, ..., Ljung K, Novák O

Plant J. 116 (6) 1825-1841 [2023-12-00; online 2023-09-08]

Flexure wood formation via growth reprogramming in hybrid aspen involves jasmonates and polyamines and transcriptional changes resembling tension wood development.

Urbancsok J, Donev EN, Sivan P, ..., Street NR, Mellerowicz EJ

New Phytol. 240 (6) 2312-2334 [2023-12-00; online 2023-10-19]

Changes in cell wall composition due to a pectin biosynthesis enzyme GAUT10 impact root growth.

Dash L, Swaminathan S, Šimura J, ..., Zabotina OA, Kelley DR

Plant Physiol. 193 (4) 2480-2497 [2023-11-22; online 2023-08-22]

Photo-physical characterization of high triplet yield brominated fluoresceins by transient state (TRAST) spectroscopy.

Demirbay B, Baryshnikov G, Haraldsson M, ..., Ågren H, Widengren J

Methods Appl. Fluoresc. 11 (4) - [2023-10-03; online 2023-10-03]

Chemical Biology Consortium Sweden [Collaborative] Swedish Metabolomics Centre [Service]

Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity.

Rodriguez-Zabala M, Ramakrishnan R, Reinbach K, ..., Woods NB, Järås M

Blood Adv 7 (18) 5382-5395 [2023-09-26; online 2023-07-28]

Clinical Genomics [Service] Clinical Genomics Lund [Service] Swedish Metabolomics Centre [Service]

Pyrroloquinoline quinone drives ATP synthesis in vitro and in vivo and provides retinal ganglion cell neuroprotection.

Canovai A, Tribble JR, Jöe M, ..., Dal Monte M, Williams PA

Acta Neuropathol Commun 11 (1) 146 [2023-09-08; online 2023-09-08]

Verticillium longisporum phospholipase VlsPLA2 is a virulence factor that targets host nuclei and modulates plant immunity.

Rafiei V, Vélëz H, Piombo E, Dubey M, Tzelepis G

Mol. Plant Pathol. 24 (9) 1078-1092 [2023-09-00; online 2023-05-12]

Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre [Service]

Amyloids of α-Synuclein Promote Chemical Transformations of Neuronal Cell Metabolites.

Horvath I, Mohamed KA, Kumar R, Wittung-Stafshede P

Int J Mol Sci 24 (16) - [2023-08-16; online 2023-08-16]

An Okinawan-Based Nordic Diet Leads to Profound Effects on Gut Microbiota and Plasma Metabolites Linked to Glucose and Lipid Metabolism.

Manoharan L, Roth B, Bang C, Stenlund H, Ohlsson B

Nutrients 15 (14) - [2023-07-24; online 2023-07-24]

Bioinformatics (NBIS) [Collaborative] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre [Collaborative]

Endophytic Beauveria bassiana induces biosynthesis of flavonoids in oilseed rape following both seed inoculation and natural colonization.

Muola A, Birge T, Helander M, ..., Saikkonen K, Fuchs B

Pest Manag Sci - (-) - [2023-07-19; online 2023-07-19]

Salicylic acid metabolism and signalling coordinate senescence initiation in aspen in nature.

Lihavainen J, Šimura J, Bag P, ..., Ljung K, Jansson S

Nat Commun 14 (1) 4288 [2023-07-18; online 2023-07-18]

NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Impact of xylan on field productivity and wood saccharification properties in aspen.

Derba-Maceluch M, Sivan P, Donev EN, ..., Jönsson LJ, Mellerowicz EJ

Front Plant Sci 14 (-) 1218302 [2023-07-17; online 2023-07-17]

Flavodiiron-mediated O2 photoreduction at photosystem I acceptor-side provides photoprotection to conifer thylakoids in early spring.

Bag P, Shutova T, Shevela D, ..., Messinger J, Jansson S

Nat Commun 14 (1) 3210 [2023-06-03; online 2023-06-03]

Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment.

Svensson Akusjärvi S, Krishnan S, Ambikan AT, ..., Sönnerborg A, Neogi U

AIDS 37 (7) 1023-1033 [2023-06-01; online 2023-03-21]

Transcriptome and metabolome profiling identify factors potentially involved in pro-vitamin A accumulation in cassava landraces.

Olayide P, Alexandersson E, Tzfadia O, ..., Gisel A, Stavolone L

Plant Physiol Biochem 199 (-) 107713 [2023-06-00; online 2023-04-24]

Retention of essential fatty acids in fish differs by species, habitat use and nutritional quality of prey.

Bandara T, Brugel S, Andersson A, Lau DCP

Ecol Evol 13 (6) e10158 [2023-06-00; online 2023-06-01]

Variation in fatty acid content among benthic invertebrates in a seasonally driven system

Hedberg P, Lau DCP, Albert S, Winder M

Limnol Oceanogr Letters - (-) - [2023-05-22; online 2023-05-22]

Structural elucidation of 3-nitrophenylhydrazine derivatives of tricarboxylic acid cycle acids and optimization of their fragmentation to boost sensitivity in liquid chromatography-mass spectrometry.

Hodek O, Henderson J, Argemi-Muntadas L, Khan A, Moritz T

Journal of Chromatography B 1222 (-) 123719 [2023-05-01; online 2023-04-11]

Inhibition of VEGF-B signaling prevents non-alcoholic fatty liver disease development by targeting lipolysis in the white adipose tissue.

Falkevall A, Mehlem A, Folestad E, ..., Nash A, Eriksson U

J Hepatol 78 (5) 901-913 [2023-05-00; online 2023-01-27]

Flexible Organic Electronic Ion Pump for Flow-Free Phytohormone Delivery into Vasculature of Intact Plants.

Bernacka-Wojcik I, Talide L, Abdel Aziz I, ..., Niittylä T, Stavrinidou E

Adv Sci (Weinh) 10 (14) e2206409 [2023-05-00; online 2023-03-19]

Low-grade glioma risk SNP rs11706832 is associated with type I interferon response pathway genes in cell lines.

Rosenbaum A, Dahlin AM, Andersson U, ..., Wibom C, Melin B

Sci Rep 13 (1) 6777 [2023-04-25; online 2023-04-25]

Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells.

Green AC, Marttila P, Kiweler N, ..., Henriksson M, Meiser J

Nat Metab 5 (4) 642-659 [2023-04-00; online 2023-04-03]

Drug Discovery and Development [Collaborative] Swedish Metabolomics Centre [Collaborative]

SLC38A10 Deficiency in Mice Affects Plasma Levels of Threonine and Histidine in Males but Not in Females: A Preliminary Characterization Study of SLC38A10-/- Mice.

Lindberg FA, Nordenankar K, Forsberg EC, Fredriksson R

Genes 14 (4) - [2023-03-30; online 2023-03-30]

NGI Short read [Service] NGI Uppsala (Uppsala Genome Center) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Rapid and accurate determination of protein content in North Atlantic seaweed by NIR and FTIR spectroscopies.

Niemi C, Mortensen AM, Rautenberger R, ..., Gorzsás A, Gentili FG

Food Chem 404 (Pt B) 134700 [2023-03-15; online 2022-10-19]

Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming.

Pateras IS, Williams C, Gianniou DD, ..., Gilthorpe JD, Frisan T

J Transl Med 21 (1) 169 [2023-03-03; online 2023-03-03]

Chitosan-Modified Polyethyleneimine Nanoparticles for Enhancing the Carboxylation Reaction and Plants' CO2 Uptake.

Routier C, Vallan L, Daguerre Y, ..., Pavlopoulou E, Stavrinidou E

ACS Nano 17 (4) 3430-3441 [2023-02-28; online 2023-02-16]

Targeting the gut-lung axis by synbiotic feeding to infants in a randomized controlled trial.

Sjödin KS, Sjödin A, Ruszczyński M, ..., Szajewska H, West CE

BMC Biol. 21 (1) 38 [2023-02-20; online 2023-02-20]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Endosperm cellularization failure induces a dehydration-stress response leading to embryo arrest.

Xu W, Sato H, Bente H, Santos-González J, Köhler C

Plant Cell 35 (2) 874-888 [2023-02-20; online 2022-11-26]

NGI Short read [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Cohort profile: The Clinical and Multi-omic (CAMO) cohort, part of the Norwegian Women and Cancer (NOWAC) study.

Delgado AB, Tylden ES, Lukic M, ..., Lund E, Olsen KS

PLoS ONE 18 (2) e0281218 [2023-02-06; online 2023-02-06]

Simultaneous membrane and RNA binding by tick-borne encephalitis virus capsid protein.

Pulkkinen LIA, Barrass SV, Lindgren M, ..., Lundmark R, Butcher SJ

PLoS Pathog. 19 (2) e1011125 [2023-02-00; online 2023-02-14]

Chemical composition and species identification of microalgal biomass grown at pilot-scale with municipal wastewater and CO2 from flue gases.

Lage S, Gentili FG

Chemosphere 313 (-) 137344 [2023-02-00; online 2022-11-26]

The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1.

Park JH, Nordström U, Tsiakas K, ..., Marklund SL, Andersen PM

Brain Commun 5 (1) fcad017 [2023-01-27; online 2023-01-27]

Biocontrol Effect of Clonostachys rosea on Fusarium graminearum Infection and Mycotoxin Detoxification in Oat (Avena sativa).

Khairullina A, Micic N, Jørgensen HJL, ..., Collinge DB, Jensen B

Plants (Basel) 12 (3) - [2023-01-21; online 2023-01-21]

Fluorogenic properties of 4-dimethylaminocinnamaldehyde (DMACA) enable high resolution imaging of cell-wall-bound proanthocyanidins in plant root tissues.

Chowdhury J, Ferdous J, Lihavainen J, Albrectsen BR, Lundberg-Felten J

Front Plant Sci 13 (-) 1060804 [2023-01-16; online 2023-01-16]

Cytokinin signaling regulates two-stage inflorescence arrest in Arabidopsis.

Walker CH, Ware A, Šimura J, ..., Wilson Z, Bennett T

Plant Physiol. 191 (1) 479-495 [2023-01-02; online 2022-11-05]

Effects of conventionally treated and ozonated wastewater on the damselfly larva oxylipidome in response to on-site exposure.

Späth J, Brodin T, Falås P, ..., Fick J, Nording M

Chemosphere 309 (Pt 1) 136604 [2022-12-00; online 2022-09-27]

Circum‐Arctic distribution of chemical anti‐herbivore compounds suggests biome‐wide trade‐off in defence strategies in Arctic shrubs

Lindén E, te Beest M, Abreu IN, ..., Zimmermann H, Olofsson J

Ecography 2022 (11) - [2022-11-00; online 2022-08-30]

TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis

Petkevicius K, Palmgren H, Glover MS, ..., Maresca M, Peng XR

Nat Commun 13 (1) 6020 [2022-10-14; online 2022-10-14]

IPT9, a cis-zeatin cytokinin biosynthesis gene, promotes root growth.

Antoniadi I, Mateo-Bonmatí E, Pernisová M, ..., Ljung K, Novák O

Front Plant Sci 13 (-) 932008 [2022-10-14; online 2022-10-14]

iP & OEIP – Cytokinin Micro Application Modulates Root Development with High Spatial Resolution

Pařízková B, Antoniadi I, Poxson DJ, ..., Novák O, Ljung K

Adv Materials Technologies 7 (10) 2101664 [2022-10-00; online 2022-04-28]

Autoantibodies targeting malondialdehyde-modifications in rheumatoid arthritis regulate osteoclasts via inducing glycolysis and lipid biosynthesis.

Sakuraba K, Krishnamurthy A, Sun J, ..., Catrina AI, Réthi B

J. Autoimmun. 133 (-) 102903 [2022-09-13; online 2022-09-13]

Distinct metabolic hallmarks of WHO classified adult glioma subtypes.

Björkblom B, Wibom C, Eriksson M, ..., Sandström M, Melin B

Neuro-oncology 24 (9) 1454-1468 [2022-09-01; online 2022-02-15]

Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.

Ambikan AT, Yang H, Krishnan S, ..., Benfeitas R, Neogi U

Cell Syst 13 (8) 665-681.e4 [2022-08-17; online 2022-07-08]

Affinity Proteomics Uppsala [Service] Bioinformatics Support for Computational Resources [Service] NGI Short read [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Feasibility and reliability of measures of bioactive lipids in human plasma and nasal mucosa.

Claeson AS, Lindberg RH, Gouveia-Figueira S, Nording ML

Journal of Chromatography B 1206 (-) 123357 [2022-08-15; online 2022-07-03]

Detailed Characterization of the Cell Wall Structure and Composition of Nordic Green Microalgae.

Spain O, Funk C

J. Agric. Food Chem. 70 (31) 9711-9721 [2022-08-10; online 2022-07-27]

Cryo-EM [Service] Integrated Microscopy Technologies Umeå [Service] Swedish Metabolomics Centre [Service]

Single, but not dual, attack by a biotrophic pathogen and a sap-sucking insect affects the oak leaf metabolome.

van Dijk LJA, Regazzoni EDE, Albrectsen BR, ..., Pawlowski K, Tack AJM

Front Plant Sci 13 (-) 897186 [2022-08-03; online 2022-08-03]

Metabolic control of arginine and ornithine levels paces the progression of leaf senescence.

Liebsch D, Juvany M, Li Z, ..., Guo H, Keech O

Plant Physiol. 189 (4) 1943-1960 [2022-08-01; online 2022-05-24]

Swedish Metabolomics Centre [Technology development]

Seawater browning alters community composition and reduces nutritional quality of plankton in a subarctic marine ecosystem

Bandara T, Brugel S, Andersson A, Lau DCP

Can. J. Fish. Aquat. Sci. 79 (8) 1291-1301 [2022-08-00; online 2022-08-00]

Effect and function of β-N-methylamino-L-alanine in the diatom Phaeodactylum tricornutum.

Kim SY, Rasmussen U, Rydberg S

Sci. Total Environ. 830 (-) 154778 [2022-07-15; online 2022-03-24]

Inactivation of the entire Arabidopsis group II GH3s confers tolerance to salinity and water deficit.

Casanova-Sáez R, Mateo-Bonmatí E, Šimura J, ..., Staswick P, Ljung K

New Phytol. 235 (1) 263-275 [2022-07-00; online 2022-04-16]

Combining metabolic phenotype determination with metabolomics and transcriptional analyses to reveal pathways regulated by hydroxycarboxylic acid receptor 2.

Rabe P, Gehmlich M, Peters A, ..., Nordström A, Stäubert C

Discov Oncol 13 (1) 47 [2022-06-13; online 2022-06-13]

No association in maternal serum levels of TMAO and its precursors in pre-eclampsia and in non-complicated pregnancies.

Jääskeläinen T, Kärkkäinen O, Heinonen S, Hanhineva K, Laivuori H

Pregnancy Hypertens 28 (-) 74-80 [2022-06-00; online 2022-02-26]

Dataset on seston and zooplankton fatty-acid compositions, zooplankton and phytoplankton biomass, and environmental conditions of coastal and offshore waters of the northern Baltic Sea.

Bandara T, Brugel S, Andersson A, Lau DCP

Data Brief 42 (-) 108158 [2022-06-00; online 2022-04-10]

Comparative structural analysis provides new insights into the function of R2-like ligand-binding oxidase.

Diamanti R, Srinivas V, Johansson AI, ..., Lebrette H, Högbom M

FEBS Lett. 596 (12) 1600-1610 [2022-06-00; online 2022-03-04]

Nitrogen represses haustoria formation through abscisic acid in the parasitic plant Phtheirospermum japonicum.

Kokla A, Leso M, Zhang X, ..., Yoshida S, Melnyk CW

Nat Commun 13 (1) 2976 [2022-05-27; online 2022-05-27]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

DGAT1 activity synchronises with mitophagy to protect cells from metabolic rewiring by iron depletion.

Long M, Sanchez-Martinez A, Longo M, ..., Whitworth AJ, McWilliams TG

EMBO J. 41 (10) e109390 [2022-05-16; online 2022-04-12]

Nitrate fertilization may delay autumn leaf senescence, while amino acid treatments do not.

Fataftah N, Edlund E, Lihavainen J, ..., Näsholm T, Jansson S

Physiol Plantarum 174 (3) e13690 [2022-05-00; online 2022-04-24]

Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice.

Skoug C, Holm C, Duarte JMN

J. Lipid Res. 63 (5) 100195 [2022-05-00; online 2022-03-15]

Wastewater effluent affects behaviour and metabolomic endpoints in damselfly larvae.

Späth J, Fick J, McCallum E, ..., Nording ML, Brodin T

Sci Rep 12 (1) 6830 [2022-04-26; online 2022-04-26]

Auxin boosts energy generation pathways to fuel pollen maturation in barley.

Amanda D, Frey FP, Neumann U, ..., Ljung K, Acosta IF

Curr. Biol. 32 (8) 1798-1811.e8 [2022-04-25; online 2022-03-21]

SLC38A10 Regulate Glutamate Homeostasis and Modulate the AKT/TSC2/mTOR Pathway in Mouse Primary Cortex Cells.

Tripathi R, Aggarwal T, Lindberg FA, Klemm AH, Fredriksson R

Front Cell Dev Biol 10 (-) 854397 [2022-04-05; online 2022-04-05]

Autoimmunity and Serology Profiling [Service] Swedish Metabolomics Centre [Service]

Timing is everything - obtaining accurate measures of plant uptake of amino acids.

Svennerstam H, Jämtgård S

New Phytol. 234 (1) 311-318 [2022-04-00; online 2022-02-02]

Gastrointestinal mucus in dog: Physiological characteristics, composition, and structural properties.

Dubbelboer IR, Barmpatsalou V, Rodler A, ..., Häggström J, Bergström CAS

Eur J Pharm Biopharm 173 (-) 92-102 [2022-04-00; online 2022-02-25]

Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre [Service]

Mixed-mode chromatography-mass spectrometry enables targeted and untargeted screening of carboxylic acids in biological samples.

Hodek O, Argemi-Muntadas L, Khan A, Moritz T

Anal. Methods 14 (10) 1015-1022 [2022-03-10; online 2022-03-10]

Swedish Metabolomics Centre [Technology development]

Alterations in Self-Aggregating Neuropeptides in Cerebrospinal Fluid of Patients with Parkinsonian Disorders.

Zhu S, Bäckström D, Forsgren L, Trupp M

J Parkinsons Dis 12 (4) 1169-1189 [2022-03-08; online 2022-03-08]

The chemical composition and antioxidant activity of mandaçaia (melipona quadrifasciata) geopropolis varies more due to region than month of collection.

Gabriel MB, Carneiro MJ, de Camargo RCR, Sawaya ACHF

Nat Prod Res 36 (6) 1626-1630 [2022-03-00; online 2021-03-10]

Impaired phosphocreatine metabolism in white adipocytes promotes inflammation.

Maqdasy S, Lecoutre S, Renzi G, ..., Mejhert N, Rydén M

Nat Metab 4 (2) 190-202 [2022-02-00; online 2022-02-14]

Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection.

Mikaeloff F, Svensson Akusjärvi S, Ikomey GM, ..., Benfeitas R, Neogi U

Commun Biol 5 (1) 27 [2022-01-11; online 2022-01-11]

Metabolomics reveals changes in metabolite profiles due to growth and metamorphosis during the ontogeny of the northern damselfly.

Späth J, Brodin T, McCallum E, ..., Fick J, Nording ML

J Insect Physiol 136 (-) 104341 [2022-01-00; online 2021-11-27]

Influence of lipid extraction and processing conditions on hydrothermal conversion of microalgae feedstocks – Effect on hydrochar composition, secondary char formation and phytotoxicity

Benavente V, Lage S, Gentili FG, Jansson S

Chemical Engineering Journal 428 (-) 129559 [2022-01-00; online 2022-01-00]

Improved Peripheral and Hepatic Insulin Sensitivity after Lifestyle Interventions in Type 2 Diabetes Is Associated with Specific Metabolomic and Lipidomic Signatures in Skeletal Muscle and Plasma.

Chorell E, Otten J, Stomby A, ..., Svensson M, Olsson T

Metabolites 11 (12) 834 [2021-12-03; online 2021-12-03]

Physiological properties, composition and structural profiling of porcine gastrointestinal mucus.

Barmpatsalou V, Dubbelboer IR, Rodler A, ..., Pedersen BL, Bergström CAS

Eur J Pharm Biopharm 169 (-) 156-167 [2021-12-00; online 2021-10-20]

Global Proteomics and Proteogenomics [Service] Integrated Microscopy Technologies Umeå [Service] Swedish Metabolomics Centre [Service]

Lowered nutritional quality of plankton caused by global environmental changes.

Lau DCP, Jonsson A, Isles PDF, Creed IF, Bergström AK

Glob Chang Biol 27 (23) 6294-6306 [2021-12-00; online 2021-09-30]

Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health.

Marabita F, James T, Karhu A, ..., Sallinen R, Kallioniemi O

Cell Syst - (-) - [2021-11-30; online 2021-11-30]

Autoimmunity and Serology Profiling [Service] Swedish Metabolomics Centre [Collaborative]

Symptoms and oxylipins in plasma before and after exposure to rooms in which individuals have both experienced and not experienced building-related symptoms - an exploratory study.

Claeson AS, Sommar J, Liljelind I

Int J Environ Health Res - (-) 1-11 [2021-10-19; online 2021-10-19]

Imatinib protects against human beta-cell death via inhibition of mitochondrial respiration and activation of AMPK.

Elksnis A, Schiffer TA, Palm F, ..., Welsh N, Wang X

Clin Sci (Lond) 135 (19) 2243-2263 [2021-10-14; online 2021-09-28]

Unraveling the Metabolic Derangements Occurring in Non-infarcted Areas of Pig Hearts With Chronic Heart Failure.

Correia C, Wang QD, Linhardt G, ..., Jennbacken K, Synnergren J

Front Cardiovasc Med 8 (-) 753470 [2021-10-13; online 2021-10-13]

Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction.

Zhou X, Mikaeloff F, Curbo S, ..., Neogi U, Karlsson A

Hum. Mol. Genet. 30 (21) 2012-2026 [2021-10-13; online 2021-06-26]

Potassium transporter TRH1/KUP4 contributes to distinct auxin-mediated root system architecture responses.

Templalexis D, Tsitsekian D, Liu C, ..., Hatzopoulos P, Rigas S

Plant Physiol. - (-) - [2021-10-11; online 2021-10-11]

Broadening the roles of UDP-glycosyltransferases in auxin homeostasis and plant development.

Mateo-Bonmatí E, Casanova-Sáez R, Šimura J, Ljung K

New Phytol. 232 (2) 642-654 [2021-10-00; online 2021-08-10]

The liver-alpha-cell axis after a mixed meal and during weight loss in type 2 diabetes.

Otten J, Stomby A, Waling M, ..., Holst JJ, Olsson T

Endocr Connect 10 (9) 1101-1110 [2021-09-09; online 2021-09-09]

Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes.

Sjögren RJO, Rizo-Roca D, Chibalin AV, ..., Näslund E, Zierath JR

Diabetologia 64 (9) 2077-2091 [2021-09-00; online 2021-06-16]

Novel Microdialysis Technique Reveals a Dramatic Shift in Metabolite Secretion during the Early Stages of the Interaction between the Ectomycorrhizal Fungus Pisolithus microcarpus and Its Host Eucalyptus grandis.

Plett KL, Buckley S, Plett JM, ..., Lundberg-Felten J, Jämtgård S

Microorganisms 9 (9) - [2021-08-26; online 2021-08-26]

Three weeks of interrupting sitting lowers fasting glucose and glycemic variability, but not glucose tolerance, in free-living women and men with obesity.

Smith JAB, Savikj M, Sethi P, ..., Zierath JR, Näslund E

Am J Physiol Endocrinol Metab 321 (2) E203-E216 [2021-08-01; online 2021-06-21]

Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis.

Olsson M, Hellman U, Wixner J, Anan I

Amyloid - (-) 1-9 [2021-07-28; online 2021-07-28]

Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet.

Stenlund H, Nilholm C, Chorell E, ..., D'Amato M, Ohlsson B

Metabolites 11 (7) - [2021-07-04; online 2021-07-04]

Nicotinamide provides neuroprotection in glaucoma by protecting against mitochondrial and metabolic dysfunction.

Tribble JR, Otmani A, Sun S, ..., Votruba M, Williams PA

Redox Biol 43 (-) 101988 [2021-07-00; online 2021-04-24]

HIV-Infected Individuals on ART With Impaired Immune Recovery Have Altered Plasma Metabolite Profiles.

Nyström S, Govender M, Yap SH, ..., Rajasuriar R, Larsson M

Open Forum Infect Dis 8 (7) ofab288 [2021-07-00; online 2021-06-02]

Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity.

Mendham AE, Goedecke JH, Zeng Y, ..., Olsson T, Chorell E

Diabetologia 64 (7) 1642-1659 [2021-07-00; online 2021-03-26]

A metabolomic study of Gomphrena agrestis in Brazilian Cerrado suggests drought-adaptive strategies on metabolism.

Melo GA, Abreu IN, de Oliveira MB, ..., Pimenta MAS, Moritz T

Sci Rep 11 (1) 12933 [2021-06-21; online 2021-06-21]

The chemical compound 'Heatin' stimulates hypocotyl elongation and interferes with the Arabidopsis NIT1-subfamily of nitrilases.

van der Woude L, Piotrowski M, Klaasse G, ..., Smeekens S, van Zanten M

Plant J. 106 (6) 1523-1540 [2021-06-00; online 2021-05-06]

Chemical Biology Consortium Sweden [Service] Swedish Metabolomics Centre [Service]

Loss of Arabidopsis matrix metalloproteinase-5 affects root development and root bacterial communities during drought stress.

Mishra LS, Kim SY, Caddell DF, Coleman-Derr D, Funk C

Physiol Plantarum 172 (2) 1045-1058 [2021-06-00; online 2020-12-16]

Factors Affecting Detoxification of Softwood Enzymatic Hydrolysates Using Sodium Dithionite

Ilanidis D, Stagge S, Alriksson B, Jönsson LJ

Processes 9 (5) 887 [2021-05-18; online 2021-05-18]

Dynamics of Auxin and Cytokinin Metabolism during Early Root and Hypocotyl Growth in Theobroma cacao.

Mboene Noah A, Casanova-Sáez R, Makondy Ango RE, ..., Niemenak N, Ljung K

Plants (Basel) 10 (5) - [2021-05-12; online 2021-05-12]

Stem girdling affects the onset of autumn senescence in aspen in interaction with metabolic signals.

Lihavainen J, Edlund E, Björkén L, ..., Robinson KM, Jansson S

Physiol Plantarum 172 (1) 201-217 [2021-05-00; online 2021-01-07]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Metabolomic profiling reveals plasma GlycA and GlycB as a potential biomarkers for treatment efficiency in rheumatoid arthritis.

Dudka I, Chachaj A, Sebastian A, ..., Gröbner G, Szuba A

Journal of Pharmaceutical and Biomedical Analysis 197 (-) 113971 [2021-04-15; online 2021-02-17]

Swedish Metabolomics Centre [Collaborative] Swedish NMR Centre [Collaborative]

Identification of human glucocorticoid response markers using integrated multi-omic analysis from a randomized crossover trial.

Chantzichristos D, Svensson PA, Garner T, ..., Stevens A, Johannsson G

Elife 10 (-) - [2021-04-06; online 2021-04-06]

Modulation of Arabidopsis root growth by specialized triterpenes.

Bai Y, Fernández-Calvo P, Ritter A, ..., Goossens A, Pollier J

New Phytol. 230 (1) 228-243 [2021-04-00; online 2021-01-19]

Swedish Metabolomics Centre

Function of the pseudo phosphotransfer proteins has diverged between rice and Arabidopsis.

Vaughan-Hirsch J, Tallerday EJ, Burr CA, ..., Bishopp A, Kieber JJ

Plant J. 106 (1) 159-173 [2021-04-00; online 2021-02-08]

Plasma oxylipin levels associated with preterm birth in preterm labor✰.

Svenvik M, Raffetseder J, Brudin L, ..., Ernerudh J, Nording ML

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 166 (-) 102251 [2021-03-00; online 2021-01-23]

Plasma metabolomics of presymptomatic PSEN1-H163Y mutation carriers: a pilot study.

Natarajan K, Ullgren A, Khoshnood B, ..., Blennow K, Graff C

Ann Clin Transl Neurol 8 (3) 579-591 [2021-03-00; online 2021-01-21]

Bioinformatics (NBIS) [Service] Bioinformatics Support and Infrastructure [Service] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Service] Swedish Metabolomics Centre [Service]

Overexpression of vesicle-associated membrane protein PttVAP27-17 as a tool to improve biomass production and the overall saccharification yields in Populus trees.

Gandla ML, Mähler N, Escamez S, ..., Tuominen H, Jönsson LJ

Biotechnol Biofuels 14 (1) 43 [2021-02-16; online 2021-02-16]

LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes.

Herdenberg C, Mutie PM, Billing O, ..., Franks PW, Hedman H

Commun Biol 4 (1) 90 [2021-01-19; online 2021-01-19]

Sucrose synthase determines carbon allocation in developing wood and alters carbon flow at the whole tree level in aspen.

Dominguez PG, Donev E, Derba-Maceluch M, ..., Mellerowicz EJ, Niittylä T

New Phytol. 229 (1) 186-198 [2021-01-00; online 2020-07-03]

Swedish Metabolomics Centre Swedish NMR Centre [Collaborative]

Studies of moss reproductive development indicate that auxin biosynthesis in apical stem cells may constitute an ancestral function for focal growth control.

Landberg K, Šimura J, Ljung K, Sundberg E, Thelander M

New Phytol. 229 (2) 845-860 [2021-01-00; online 2020-10-04]

Lysophospholipids as Predictive Markers of ST-Elevation Myocardial Infarction (STEMI) and Non-ST-Elevation Myocardial Infarction (NSTEMI).

Chorell E, Olsson T, Jansson JH, Wennberg P

Metabolites 11 (1) 25 [2020-12-31; online 2020-12-31]

The Bactericidal Fatty Acid Mimetic 2CCA-1 Selectively Targets Pneumococcal Extracellular Polyunsaturated Fatty Acid Metabolism.

Reithuber E, Nannapaneni P, Rzhepishevska O, ..., Henriques-Normark B, Mellroth P

MBio 11 (6) e03027-20 [2020-12-15; online 2020-12-15]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

HY5 and phytochrome activity modulate shoot-to-root coordination during thermomorphogenesis in Arabidopsis.

Gaillochet C, Burko Y, Platre MP, ..., Chory J, Busch W

Development 147 (24) - [2020-12-15; online 2020-12-15]

Reaction Wood Anatomical Traits and Hormonal Profiles in Poplar Bent Stem and Root.

De Zio E, Montagnoli A, Karady M, ..., Chiatante D, Trupiano D

Front Plant Sci 11 (-) 590985 [2020-12-07; online 2020-12-07]

Differentiation of two Maytenus species and their hybrid via untargeted metabolomics

Antunes ERM, Duarte RS, Moritz T, Sawaya ACHF

Industrial Crops and Products 158 (-) 113014 [2020-12-00; online 2020-12-00]

Changes in lipid and carotenoid metabolism in Chlamydomonas reinhardtii during induction of CO2-concentrating mechanism: Cellular response to low CO2 stress

Abreu IN, Aksmann A, Bajhaiya AK, ..., Selstam E, Moritz T

Algal Research 52 (-) 102099 [2020-12-00; online 2020-12-00]

Swedish Metabolomics Centre

A metabolite roadmap of the wood-forming tissue in Populus tremula.

Abreu IN, Johansson AI, Sokołowska K, ..., Street NR, Moritz T

New Phytol. 228 (5) 1559-1572 [2020-12-00; online 2020-08-27]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Collaborative]

Identification of Pre-Diagnostic Metabolic Patterns for Glioma Using Subset Analysis of Matched Repeated Time Points.

Jonsson P, Antti H, Späth F, Melin B, Björkblom B

Cancers (Basel) 12 (11) 3349 [2020-11-12; online 2020-11-12]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

The Structure of Riparian Vegetation in Agricultural Landscapes Influences Spider Communities and Aquatic-Terrestrial Linkages

Ramberg E, Burdon FJ, Sargac J, ..., Johnson RK, McKie BG

Water 12 (10) 2855 [2020-10-14; online 2020-10-14]

HEARTBREAK Controls Post-translational Modification of INDEHISCENT to Regulate Fruit Morphology in Capsella.

Dong Y, Majda M, Šimura J, ..., Smith RS, Østergaard L

Curr. Biol. 30 (19) 3880-3888.e5 [2020-10-05; online 2020-08-13]

Swedish Metabolomics Centre

Integration of molecular profiles in a longitudinal wellness profiling cohort.

Tebani A, Gummesson A, Zhong W, ..., Uhlen M, Fagerberg L

Nat Commun 11 (1) 4487 [2020-09-08; online 2020-09-08]

Affinity Proteomics Stockholm [Collaborative] Autoimmunity and Serology Profiling [Collaborative] Bioinformatics (NBIS) [Collaborative] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] Cellular Immunomonitoring [Collaborative] Swedish Metabolomics Centre [Collaborative]

Cell-surface receptors enable perception of extracellular cytokinins.

Antoniadi I, Novák O, Gelová Z, ..., Ljung K, Turnbull C

Nat Commun 11 (1) 4284 [2020-08-27; online 2020-08-27]

VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content.

Moessinger C, Nilsson I, Muhl L, ..., Skogsberg J, Eriksson U

EMBO Rep. 21 (7) e49343 [2020-07-03; online 2020-05-24]

Serum Metabolites in Hand-Arm Vibration Exposed Workers.

Vihlborg P, Graff P, Hagenbjörk A, ..., Bryngelsson IL, Eriksson K

J Occup Environ Med 62 (7) 460-465 [2020-07-00; online 2020-07-31]

Auxin export from proximal fruits drives arrest in temporally competent inflorescences

Ware A, Walker CH, Šimura J, ..., Wilson ZA, Bennett T

NPLANTS 6 (6) 699-707 [2020-05-25; online 2020-05-25]

Integration of whole-body [18F]FDG PET/MRI with non-targeted metabolomics can provide new insights on tissue-specific insulin resistance in type 2 diabetes.

Diamanti K, Visvanathar R, Pereira MJ, ..., Wadelius C, Ahlström H

Sci Rep 10 (1) 8343 [2020-05-20; online 2020-05-20]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Comprehensive metabolomics analysis of prostate cancer tissue in relation to tumor aggressiveness and TMPRSS2-ERG fusion status.

Dudka I, Thysell E, Lundquist K, ..., Wikström P, Gröbner G

BMC Cancer 20 (1) 437 [2020-05-18; online 2020-05-18]

Swedish Metabolomics Centre [Service] Swedish NMR Centre [Collaborative]

Lipid accumulation controls the balance between surface connection and scission of caveolae.

Hubert M, Larsson E, Vegesna NVG, ..., Moodie LW, Lundmark R

Elife 9 (-) - [2020-05-04; online 2020-05-04]

Integrated Microscopy Technologies Umeå [Collaborative] Swedish Metabolomics Centre [Collaborative]

Plant resistance does not compromise parasitoid-based biocontrol of a strawberry pest.

Weber D, Egan PA, Muola A, Ericson LE, Stenberg JA

Sci Rep 10 (1) 5899 [2020-04-03; online 2020-04-03]

Metabolomics analyses in non-diabetic middle-aged individuals reveal metabolites impacting early glucose disturbances and insulin sensitivity.

Bos MM, Noordam R, Bennett K, ..., Surowiec I, van Heemst D

Metabolomics 16 (3) 35 [2020-03-02; online 2020-03-02]

Metabolic Profiling and Compound-Class Identification Reveal Alterations in Serum Triglyceride Levels in Mice Immunized with Human Vaccine Adjuvant Alum.

Khoomrung S, Nookaew I, Sen P, ..., Harandi AM, Nielsen J

J. Proteome Res. 19 (1) 269-278 [2020-01-03; online 2019-11-01]

Metabolic response patterns in brain microdialysis fluids and serum during interstitial cisplatin treatment of high-grade glioma.

Björkblom B, Jonsson P, Tabatabaei P, ..., Bergenheim AT, Antti H

Br. J. Cancer 122 (2) 221-232 [2020-01-00; online 2019-12-10]

Autoregulation of RCO by Low-Affinity Binding Modulates Cytokinin Action and Shapes Leaf Diversity.

Hajheidari M, Wang Y, Bhatia N, ..., Gan X, Tsiantis M

Curr. Biol. 29 (24) 4183-4192.e6 [2019-12-16; online 2019-11-21]

HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion.

van der Woude LC, Perrella G, Snoek BL, ..., Kaiserli E, van Zanten M

Proc. Natl. Acad. Sci. U.S.A. 116 (50) 25343-25354 [2019-12-10; online 2019-11-25]

GLUL Ablation Can Confer Drug Resistance to Cancer Cells via a Malate-Aspartate Shuttle-Mediated Mechanism.

Muthu M, Kumar R, Syed Khaja AS, ..., Persson JL, Nordström A

Cancers (Basel) 11 (12) 1945 [2019-12-05; online 2019-12-05]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Targeted Multiple Reaction Monitoring Analysis of CSF Identifies UCHL1 and GPNMB as Candidate Biomarkers for ALS.

Zhu S, Wuolikainen A, Wu J, ..., Forsgren L, Trupp M

J. Mol. Neurosci. 69 (4) 643-657 [2019-12-00; online 2019-11-12]

PECTIN ACETYLESTERASE9 Affects the Transcriptome and Metabolome and Delays Aphid Feeding.

Kloth KJ, Abreu IN, Delhomme N, ..., Moritz T, Albrectsen BR

Plant Physiol. 181 (4) 1704-1720 [2019-12-00; online 2019-09-24]

Bioinformatics Support for Computational Resources [Service] NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial

He X, Parenti M, Grip T, ..., Timby N, Slupsky CM

Sci Rep 9 (1) 339 [2019-12-00; online 2019-01-23]

Intra- and inter-individual metabolic profiling highlights carnitine and lysophosphatidylcholine pathways as key molecular defects in type 2 diabetes

Diamanti K, Cavalli M, Pan G, ..., Komorowski J, Wadelius C

Sci Rep 9 (1) 9653 [2019-12-00; online 2019-07-04]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Heterologous phosphoketolase expression redirects flux towards acetate, perturbs sugar phosphate pools and increases respiratory demand in Saccharomyces cerevisiae

Bergman A, Hellgren J, Moritz T, ..., Nielsen J, Chen Y

Microb. Cell Fact. 18 (1) 25 [2019-12-00; online 2019-02-01]

Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis.

Diab J, Hansen T, Goll R, ..., Florholmen J, Forsdahl G

Metabolites 9 (12) S035-S035 [2019-11-27; online 2019-11-27]

Synthesis of Indomorphan Pseudo-Natural Product Inhibitors of Glucose Transporters GLUT-1 and -3.

Ceballos J, Schwalfenberg M, Karageorgis G, ..., Ziegler S, Waldmann H

Angew. Chem. Int. Ed. Engl. 58 (47) 17016-17025 [2019-11-18; online 2019-10-07]

A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels.

Van Moerkercke A, Duncan O, Zander M, ..., Millar AH, Van Aken O

Proc. Natl. Acad. Sci. U.S.A. 116 (46) 23345-23356 [2019-11-12; online 2019-10-29]

Two-step derivatization for determination of sugar phosphates in plants by combined reversed phase chromatography/tandem mass spectrometry.

Rende U, Niittylä T, Moritz T

Plant Methods 15 (1) 127 [2019-11-07; online 2019-11-07]

A bacterial assay for rapid screening of IAA catabolic enzymes.

Brunoni F, Collani S, Šimura J, ..., Bellini C, Ljung K

Plant Methods 15 (1) 126 [2019-11-04; online 2019-11-04]

Yeast Volatomes Differentially Affect Larval Feeding in an Insect Herbivore.

Ljunggren J, Borrero-Echeverry F, Chakraborty A, ..., Witzgall P, Bengtsson M

Appl. Environ. Microbiol. 85 (21) - [2019-11-01; online 2019-10-16]

PIN-driven auxin transport emerged early in streptophyte evolution.

Skokan R, Medvecká E, Viaene T, ..., Petrášek J, Friml J

NPLANTS 5 (11) 1114-1119 [2019-11-00; online 2019-11-11]

Lipidomics in Ulcerative Colitis Reveal Alteration in Mucosal Lipid Composition Associated With the Disease State.

Diab J, Hansen T, Goll R, ..., Florholmen J, Forsdahl G

Inflamm Bowel Dis 25 (11) 1780-1787 [2019-10-18; online 2019-05-12]

Implantable Organic Electronic Ion Pump Enables ABA Hormone Delivery for Control of Stomata in an Intact Tobacco Plant.

Bernacka-Wojcik I, Huerta M, Tybrandt K, ..., Berggren M, Stavrinidou E

Small 15 (43) e1902189 [2019-10-00; online 2019-09-12]

Significant Changes in Metabolic Profiles after Intervention with Selenium and Coenzyme Q10 in an Elderly Population.

Alehagen U, Johansson P, Aaseth J, ..., Lundstedt-Enkel K, Lundstedt T

Biomolecules 9 (10) - [2019-09-30; online 2019-09-30]

Leaf metabolic signatures induced by real and simulated herbivory in black mustard (Brassica nigra).

Papazian S, Girdwood T, Wessels BA, ..., Moritz T, Albrectsen BR

Metabolomics 15 (10) 130 [2019-09-28; online 2019-09-28]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Combining microdialysis with metabolomics to characterize the in situ composition of dissolved organic compounds in boreal forest soil

Randewig D, Marshall JD, Näsholm T, Jämtgård S

Soil Biology and Biochemistry 136 (-) 107530 [2019-09-00; online 2019-09-00]

Publisher Correction: Metabolic phenotype of breast-fed infants, and infants fed standard formula or bovine MFGM supplemented formula: a randomized controlled trial.

He X, Parenti M, Grip T, ..., Timby N, Slupsky CM

Sci Rep 9 (1) 12382 [2019-08-22; online 2019-08-22]

Joint and unique multiblock analysis of biological data - multiomics malaria study.

Surowiec I, Skotare T, Sjögren R, ..., Normark J, Trygg J

Faraday Discuss. 218 (0) 268-283 [2019-08-15; online 2019-05-24]

A role for the auxin precursor anthranilic acid in root gravitropism via regulation of PIN-FORMED protein polarity and relocalisation in Arabidopsis.

Doyle SM, Rigal A, Grones P, ..., Novák O, Robert S

New Phytol. 223 (3) 1420-1432 [2019-08-00; online 2019-06-07]

Chemical Biology Consortium Sweden [Service] Swedish Metabolomics Centre [Service]

Vitamin D and Phenylbutyrate Supplementation Does Not Modulate Gut Derived Immune Activation in HIV-1.

Missailidis C, Sørensen N, Ashenafi S, ..., Brighenti S, Bergman P

Nutrients 11 (7) 1675 [2019-07-21; online 2019-07-21]

The molecular pathogenesis of superoxide dismutase 1-linked ALS is promoted by low oxygen tension.

Keskin I, Forsgren E, Lehmann M, ..., Marklund SL, Gilthorpe JD

Acta Neuropathol. 138 (1) 85-101 [2019-07-00; online 2019-03-12]

Alterations in the metabolism of phospholipids, bile acids and branched-chain amino acids predicts development of type 2 diabetes in black South African women: a prospective cohort study.

Zeng Y, Mtintsilana A, Goedecke JH, ..., Olsson T, Chorell E

Metabolism 95 (-) 57-64 [2019-06-00; online 2019-04-04]

Metabolic profiling of zebrafish embryo development from blastula period to early larval stages.

Dhillon SS, Torell F, Donten M, ..., Trygg J, Lundstedt T

PLoS ONE 14 (5) e0213661 [2019-05-14; online 2019-05-14]

Comparisons of analysis of fatty acid methyl ester (FAME) of microalgae by chromatographic techniques

Niemi C, Lage S, Gentili FG

Algal Research 39 (-) 101449 [2019-05-00; online 2019-05-00]

Nitrogen utilization during germination of somatic embryos of Norway spruce: revealing the importance of supplied glutamine for nitrogen metabolism

Carlsson J, Egertsdotter U, Ganeteg U, Svennerstam H

Trees 33 (2) 383-394 [2019-04-00; online 2018-11-09]

Selective auxin agonists induce specific AUX/IAA protein degradation to modulate plant development.

Vain T, Raggi S, Ferro N, ..., Pauwels L, Robert S

Proc. Natl. Acad. Sci. U.S.A. 116 (13) 6463-6472 [2019-03-26; online 2019-03-08]

Chemical Biology Consortium Sweden [Collaborative] Swedish Metabolomics Centre [Service]

Current Status and Future Prospects of Clinically Exploiting Cancer-specific Metabolism-Why Is Tumor Metabolism Not More Extensively Translated into Clinical Targets and Biomarkers?

Muthu M, Nordström A

Int J Mol Sci 20 (6) 1385 [2019-03-19; online 2019-03-19]

Regulatory Diversification of INDEHISCENT in the Capsella Genus Directs Variation in Fruit Morphology.

Dong Y, Jantzen F, Stacey N, ..., Ljung K, Østergaard L

Curr. Biol. 29 (6) 1038-1046.e4 [2019-03-18; online 2019-02-28]

Surveillance of cell wall diffusion barrier integrity modulates water and solute transport in plants.

Wang P, Calvo-Polanco M, Reyt G, ..., Boursiac Y, Salt DE

Sci Rep 9 (1) 4227 [2019-03-12; online 2019-03-12]

A Quantitative Analysis of Colonic Mucosal Oxylipins and Endocannabinoids in Treatment-Naïve and Deep Remission Ulcerative Colitis Patients and the Potential Link With Cytokine Gene Expression.

Diab J, Al-Mahdi R, Gouveia-Figueira S, ..., Florholmen J, Forsdahl G

Inflamm Bowel Dis 25 (3) 490-497 [2019-02-21; online 2018-11-27]

Metabolomic and lipidomic assessment of the metabolic syndrome in Dutch middle-aged individuals reveals novel biological signatures separating health and disease.

Surowiec I, Noordam R, Bennett K, ..., Lundstedt T, van Heemst D

Metabolomics 15 (2) 23 [2019-02-12; online 2019-02-12]

A standardized protocol for comparable analysis of GSH/GSSG by UHPLC-ESI-MSMS for human plasma.

Claeson AS, Gouveia-Figueira S, Stenlund H, Johansson AI

Journal of Chromatography B 1104 (-) 67-72 [2019-01-01; online 2018-11-10]

Tissue-specific hormone profiles from woody poplar roots under bending stress.

De Zio E, Trupiano D, Karady M, ..., Ljung K, Scippa GS

Physiol Plantarum 165 (1) 101-113 [2019-01-00; online 2018-10-15]

Auxin Function in the Brown Alga Dictyota dichotoma.

Bogaert KA, Blommaert L, Ljung K, Beeckman T, De Clerck O

Plant Physiol. 179 (1) 280-299 [2019-01-00; online 2018-11-12]

Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother's Milk Are Strongly Associated with Infant Weight at Four Months of Age-Data from the Odense Child Cohort.

Bruun S, Gouveia-Figueira S, Domellöf M, ..., Fowler CJ, Zachariassen G

Nutrients 10 (11) 1747 [2018-11-13; online 2018-11-13]

Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes.

Grip T, Dyrlund TS, Ahonen L, ..., Orešič M, Timby N

Pediatr. Res. 84 (5) 726-732 [2018-11-00; online 2018-08-04]

The Xerobranching Response Represses Lateral Root Formation When Roots Are Not in Contact with Water.

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Curr. Biol. 28 (19) 3165-3173.e5 [2018-10-08; online 2018-09-27]

Broad spectrum developmental role of Brachypodium AUX1.

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New Phytol. 219 (4) 1216-1223 [2018-09-00; online 2018-06-27]

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans

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Sci Adv 4 (8) eaar8590 [2018-08-00; online 2018-08-22]

Bioinformatics (NBIS) [Collaborative] Bioinformatics Long-term Support WABI [Collaborative] Bioinformatics Support for Computational Resources [Service] Bioinformatics Support, Infrastructure and Training [Collaborative] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service] Swedish Metabolomics Centre [Service]

Metabolic Profiling of Multiorgan Samples: Evaluation of MODY5/RCAD Mutant Mice.

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

J. Proteome Res. 17 (7) 2293-2306 [2018-07-06; online 2018-06-15]

A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial

Otten J, Stomby A, Waling M, ..., Hauksson J, Olsson T

Diabetologia 61 (7) 1548-1559 [2018-07-00; online 2018-04-26]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

A freshwater diatom challenged by Zn: Biochemical, physiological and metabolomic responses of Tabellaria flocculosa(Roth) Kützing.

Gonçalves S, Kahlert M, Almeida SFP, Figueira E

Environ Pollut 238 (-) 959-971 [2018-07-00; online 2018-04-28]

Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry.

Kong Z, Jia S, Chabes AL, ..., Moritz T, Chabes A

Nucleic Acids Res. 46 (11) e66 [2018-06-20; online 2018-03-20]

Plant Hormonomics: Multiple Phytohormone Profiling by Targeted Metabolomics

Šimura J, Antoniadi I, Široká J, ..., Ljung K, Novák O

Plant Physiol. 177 (2) 476-489 [2018-06-13; online 2018-04-27]

Circadian clock components control daily growth activities by modulating cytokinin levels and cell division-associated gene expression in Populus trees.

Edwards KD, Takata N, Johansson M, ..., Ljung K, Eriksson ME

Plant Cell Environ. 41 (6) 1468-1482 [2018-06-00; online 2018-04-15]

Assessing Cu impacts on freshwater diatoms: biochemical and metabolomic responses of Tabellaria flocculosa (Roth) Kützing

Gonçalves S, Kahlert M, Almeida SFP, Figueira E

Science of The Total Environment 625 (-) 1234-1246 [2018-06-00; online 2018-06-00]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Darkened Leaves Use Different Metabolic Strategies for Senescence and Survival.

Law SR, Chrobok D, Juvany M, ..., Gardeström P, Keech O

Plant Physiol. 177 (1) 132-150 [2018-05-00; online 2018-03-09]

Ultra-rapid auxin metabolite profiling for high-throughput mutant screening in Arabidopsis.

Pencík A, Casanova-Sáez R, Pilarová V, ..., Ljung K, Novák O

J. Exp. Bot. 69 (10) 2569-2579 [2018-04-27; online 2018-03-08]

Rice auxin influx carrier OsAUX1 facilitates root hair elongation in response to low external phosphate.

Giri J, Bhosale R, Huang G, ..., Swarup R, Bennett MJ

Nat Commun 9 (1) 1408 [2018-04-12; online 2018-04-12]

A mechanistic framework for auxin dependent Arabidopsis root hair elongation to low external phosphate.

Bhosale R, Giri J, Pandey BK, ..., Bennett MJ, Swarup R

Nat Commun 9 (1) 1409 [2018-04-12; online 2018-04-12]

Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

Bergenholm D, Gossing M, Wei Y, Siewers V, Nielsen J

Biotechnol. Bioeng. 115 (4) 932-942 [2018-04-00; online 2018-01-24]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

Transcriptional stimulation of rate-limiting components of the autophagic pathway improves plant fitness.

Minina EA, Moschou PN, Vetukuri RR, ..., Hofius D, Bozhkov PV

J. Exp. Bot. 69 (6) 1415-1432 [2018-03-14; online 2018-01-25]

Interferon γ treatment increases endocannabinoid and related N-acylethanolamine levels in T84 human colon carcinoma cells

Alhouayek M, Rankin L, Gouveia-Figueira S, Fowler CJ

British Journal of Pharmacology - (-) - [2018-02-05; online 2018-02-05]

A Common Peptidolytic Mechanism for Targeting Peptide Degradation in Mitochondria and Chloroplasts.

Kmiec B, Branca RMM, Murcha MW, ..., Glaser E, Teixeira PF

Mol Plant 11 (2) 342-345 [2018-02-05; online 2017-11-26]

Clinical Proteomics Mass spectrometry [Service] Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre [Service]

Red meat intake in chronic kidney disease patients: Two sides of the coin

Mafra D, Borges NA, Cardozo LFMdF, ..., Lindholm B, Stenvinkel P

Nutrition 46 (-) 26-32 [2018-02-00; online 2018-02-00]

Bioinformatics Support for Computational Resources [Service] Swedish Metabolomics Centre [Service]

A multi-omics approach reveals function of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees.

Obudulu O, Mähler N, Skotare T, ..., Trygg J, Tuominen H

BMC Genomics 19 (1) 11 [2018-01-03; online 2018-01-03]

Optimising methods for the recovery and quantification of di- and tripeptides in soil

Jämtgård S, Robinson N, Moritz T, Colgrave ML, Schmidt S

Soil Res. 56 (4) 404 [2018-00-00; online 2018-00-00]

Metabolome and transcriptome profiling reveal new insights into somatic embryo germination in Norway spruce (Picea abies).

Dobrowolska I, Businge E, Abreu IN, Moritz T, Egertsdotter U

Tree Physiol 37 (12) 1752-1766 [2017-12-01; online 2017-10-07]

The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children

Surowiec I, Gouveia-Figueira S, Orikiiriza J, ..., Normark J, Trygg J

Malar. J. 16 (1) - [2017-12-00; online 2017-09-08]

Brassinosteroid signaling-dependent root responses to prolonged elevated ambient temperature

Martins S, Montiel-Jorda A, Cayrel A, ..., Ljung K, Vert G

Nat Commun 8 (1) - [2017-12-00; online 2017-08-21]

Combined transcriptome and translatome analyses reveal a role for tryptophan-dependent auxin biosynthesis in the control of DOG1-dependent seed dormancy

Bai B, Novák O, Ljung K, Hanson J, Bentsink L

New Phytol - (-) - [2017-11-15; online 2017-11-15]

Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1

Yan Z, Liu X, Ljung K, ..., Wang M, Tao Y

Plant Physiol. 175 (3) 1438-1454 [2017-11-00; online 2017-09-20]

Multivariate strategy for the sample selection and integration of multi-batch data in metabolomics

Surowiec I, Johansson E, Torell F, ..., Jakobsson PJ, Trygg J

Metabolomics 13 (10) - [2017-10-00; online 2017-08-24]

Swedish Metabolomics Centre [Technology development]

Effects of tumour necrosis factor α upon the metabolism of the endocannabinoid anandamide in prostate cancer cells.

Karlsson J, Gouveia-Figueira S, Alhouayek M, Fowler CJ

PLoS ONE 12 (9) e0185011 [2017-09-14; online 2017-09-14]

Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root.

Di Mambro R, De Ruvo M, Pacifici E, ..., Grieneisen VA, Sabatini S

Proc. Natl. Acad. Sci. U.S.A. 114 (36) E7641-E7649 [2017-09-05; online 2017-08-22]

Enhanced Secondary- and Hormone Metabolism in Leaves of Arbuscular Mycorrhizal Medicago truncatula

Adolfsson L, Nziengui H, Abreu IN, ..., Schoefs B, Spetea C

Plant Physiol. 175 (1) 392-411 [2017-09-00; online 2017-07-11]

Nitrogen uptake and assimilation in proliferating embryogenic cultures of Norway spruce-Investigating the specific role of glutamine.

Carlsson J, Svennerstam H, Moritz T, Egertsdotter U, Ganeteg U

PLoS ONE 12 (8) e0181785 [2017-08-24; online 2017-08-24]

Dual herbivore attack and herbivore density affect metabolic profiles of Brassica nigra leaves

Ponzio C, Papazian S, Albrectsen BR, Dicke M, Gols R

Plant, Cell & Environment 40 (8) 1356-1367 [2017-08-00; online 2017-02-24]

Tuning Metabolome Coverage in Reversed Phase LC-MS Metabolomics of MeOH Extracted Samples Using the Reconstitution Solvent Composition.

Lindahl A, Sääf S, Lehtiö J, Nordström A

Anal. Chem. 89 (14) 7356-7364 [2017-07-18; online 2017-06-28]

Clinical Proteomics Mass spectrometry [Service] Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre [Technology development]

Functional metabolomics as a tool to analyze Mediator function and structure in plants.

Davoine C, Abreu IN, Khajeh K, ..., Moritz T, Björklund S

PLoS ONE 12 (6) e0179640 [2017-06-22; online 2017-06-22]

Establishment of photosynthesis is controlled by two distinct regulatory phases

Dubreuil C, Jin X, Barajas-López JdD, ..., Small ID, Strand A

Plant Physiol. - (-) pp.00435.2017 [2017-06-16; online 2017-06-16]

Cryo-EM [Service] Swedish Metabolomics Centre [Service]

Coordinated nitrogen and carbon remobilization for nitrate assimilation in leaf, sheath and root and associated cytokinin signals during early regrowth of Lolium perenne.

Roche J, Turnbull MH, Guo Q, ..., Jameson PE, Love J

Ann. Bot. 119 (8) 1353-1364 [2017-06-01; online 2017-03-24]

The effects of thawing on the plasma metabolome: evaluating differences between thawed plasma and multi-organ samples

Torell F, Bennett K, Rännar S, ..., Lundstedt T, Trygg J

Metabolomics 13 (6) - [2017-06-00; online 2017-04-17]

Metabolite quantification by NMR and LC-MS/MS reveals differences between unstimulated, stimulated, and pure parotid saliva

Figueira J, Gouveia-Figueira S, Öhman C, ..., Nording ML, Öhman A

Journal of Pharmaceutical and Biomedical Analysis 140 (-) 295-300 [2017-06-00; online 2017-06-00]

Swedish Metabolomics Centre [Service] Swedish NMR Centre [Collaborative]

Levels of oxylipins, endocannabinoids and related lipids in plasma before and after low-level exposure to acrolein in healthy individuals and individuals with chemical intolerance

Claeson AS, Gouveia-Figueira S, Häggström J, Fowler CJ, Nording ML

Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) 121 (-) 60-67 [2017-06-00; online 2017-06-00]

Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa

Näsström E, Parry CM, Vu Thieu NT, ..., Antti H, Baker S

Elife 6 (-) - [2017-05-09; online 2017-05-09]

Regulating plant physiology with organic electronics

Poxson DJ, Karady M, Gabrielsson R, ..., Simon DT, Berggren M

Proc Natl Acad Sci USA 114 (18) 4597-4602 [2017-05-02; online 2017-04-18]

Contrasting patterns of cytokinins between years in senescing aspen leaves

Edlund E, Novak O, Karady M, Ljung K, Jansson S

Plant, Cell & Environment 40 (5) 622-634 [2017-05-00; online 2017-03-27]

Discrimination of pancreatic cancer and pancreatitis by LC-MS metabolomics.

Lindahl A, Heuchel R, Forshed J, ..., Löhr M, Nordström A

Metabolomics 13 (5) 61 [2017-04-01; online 2017-04-01]

Clinical Proteomics Mass spectrometry [Service] Global Proteomics and Proteogenomics [Service] Swedish Metabolomics Centre [Service]

The anti-inflammatory compound palmitoylethanolamide inhibits prostaglandin and hydroxyeicosatetraenoic acid production by a macrophage cell line

Gabrielsson L, Gouveia-Figueira S, Häggström J, Alhouayek M, Fowler CJ

Pharmacol Res Perspect 5 (2) e00300 [2017-04-00; online 2017-02-27]

Neonatal Cord Blood Oxylipins and Exposure to Particulate Matter in the Early-Life Environment: An ENVIRONAGE Birth Cohort Study.

Martens DS, Gouveia S, Madhloum N, ..., Nording M, Nawrot TS

Environ. Health Perspect. 125 (4) 691-698 [2017-04-00; online 2016-11-05]

Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria

Orikiiriza J, Surowiec I, Lindquist E, ..., Trygg J, Normark J

Metabolomics 13 (4) - [2017-04-00; online 2017-02-23]

Altered expression of maize PLASTOCHRON1 enhances biomass and seed yield by extending cell division duration

Sun X, Cahill J, Van Hautegem T, ..., Inzé D, Nelissen H

Nat Commun 8 (-) 14752 [2017-03-16; online 2017-03-16]

Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease

Falkevall A, Mehlem A, Palombo I, ..., Nash A, Eriksson U

Cell Metabolism 25 (3) 713-726 [2017-03-00; online 2017-03-00]

Amino acid transporter mutants of Arabidopsis provides evidence that a non-mycorrhizal plant acquires organic nitrogen from agricultural soil.

Ganeteg U, Ahmad I, Jämtgård S, ..., Schmidt S, Näsholm T

Plant Cell Environ. 40 (3) 413-423 [2017-03-00; online 2016-12-13]

Longitudinal analysis of hepatic transcriptome and serum metabolome demonstrates altered lipid metabolism following the onset of hyperglycemia in spontaneously diabetic biobreeding rats.

Regnell SE, Hessner MJ, Jia S, ..., La Torre D, Lernmark Å

PLoS ONE 12 (2) e0171372 [2017-02-13; online 2017-02-13]

The Arabidopsis bZIP11 transcription factor links low-energy signalling to auxin-mediated control of primary root growth

Weiste C, Pedrotti L, Selvanayagam J, ..., Hanson J, Dröge-Laser W

PLoS Genet. 13 (2) e1006607 [2017-02-03; online 2017-02-03]

Dysregulated fatty acid metabolism in coronary ectasia: An extended lipidomic analysis.

Boles U, Pinto RC, David S, Abdullah AS, Henein MY

Int. J. Cardiol. 228 (-) 303-308 [2017-02-01; online 2016-11-11]

Defense Responses in Aspen with Altered Pectin Methylesterase Activity Reveal the Hormonal Inducers of Tyloses

Leśniewska J, Öhman D, Krzesłowska M, ..., Moritz T, Mellerowicz EJ

Plant Physiol. 173 (2) 1409-1419 [2017-02-00; online 2016-12-06]

cis-Cinnamic Acid Is a Novel, Natural Auxin Efflux Inhibitor That Promotes Lateral Root Formation

Steenackers W, Klíma P, Quareshy M, ..., Boerjan W, Vanholme B

Plant Physiol. 173 (1) 552-565 [2017-01-00; online 2016-11-11]

SHADE AVOIDANCE 4 Is Required for Proper Auxin Distribution in the Hypocotyl

Ge Y, Yan F, Zourelidou M, ..., Schwechheimer C, Tao Y

Plant Physiol. 173 (1) 788-800 [2017-01-00; online 2016-11-21]

A multi-step peptidolytic cascade for amino acid recovery in chloroplasts.

Teixeira PF, Kmiec B, Branca RM, ..., Lehtiö J, Glaser E

Nat. Chem. Biol. 13 (1) 15-17 [2017-01-00; online 2016-10-31]

Clinical Proteomics Mass spectrometry [Collaborative] Global Proteomics and Proteogenomics [Collaborative] Swedish Metabolomics Centre [Service]

Aspen phenylpropanoid genes’ expression levels correlate with genets’ tannin richness and vary both in responses to soil nitrogen and associations with phenolic profiles

Decker VHG, Bandau F, Gundale MJ, Cole CT, Albrectsen BR

Tree Physiol - (-) - [2016-12-15; online 2016-12-15]

The PLETHORA Gene Regulatory Network Guides Growth and Cell Differentiation in Arabidopsis Roots.

Santuari L, Sanchez-Perez GF, Luijten M, ..., Scheres B, Heidstra R

Plant Cell 28 (12) 2937-2951 [2016-12-00; online 2016-12-05]

Dissecting the Metabolic Role of Mitochondria during Developmental Leaf Senescence.

Chrobok D, Law SR, Brouwer B, ..., Gardeström P, Keech O

Plant Physiol. 172 (4) 2132-2153 [2016-12-00; online 2016-10-21]

The Arabidopsis TOR Kinase Specifically Regulates the Expression of Nuclear Genes Coding for Plastidic Ribosomal Proteins and the Phosphorylation of the Cytosolic Ribosomal Protein S6.

Dobrenel T, Mancera-Martínez E, Forzani C, ..., Hanson J, Meyer C

Front Plant Sci 7 (-) 1611 [2016-11-07; online 2016-11-07]

Central Metabolic Responses to Ozone and Herbivory Affect Photosynthesis and Stomatal Closure.

Papazian S, Khaling E, Bonnet C, ..., Blande JD, Albrectsen BR

Plant Physiol. 172 (3) 2057-2078 [2016-11-00; online 2016-10-21]

Metabolite and Lipid Profiling of Biobank Plasma Samples Collected Prior to Onset of Rheumatoid Arthritis.

Surowiec I, Ärlestig L, Rantapää-Dahlqvist S, Trygg J

PLoS ONE 11 (10) e0164196 [2016-10-18; online 2016-10-18]

Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.

Jia M, Andreassen T, Jensen L, ..., Moestue SA, Dahlman-Wright K

Cancer Res. 76 (19) 5634-5646 [2016-10-01; online 2016-07-28]

The Allelochemical MDCA Inhibits Lignification and Affects Auxin Homeostasis.

Steenackers W, Cesarino I, Klíma P, ..., Boerjan W, Vanholme B

Plant Physiol. 172 (2) 874-888 [2016-10-00; online 2016-08-09]

Metabolomic Quality Assessment of EDTA Plasma and Serum Samples.

Malm L, Tybring G, Moritz T, Landin B, Galli J

Biopreserv Biobank 14 (5) 416-423 [2016-10-00; online 2016-06-27]

Direct acquisition of organic N by white clover even in the presence of inorganic N

Czaban W, Jämtgård S, Näsholm T, ..., Nicolaisen M, Fomsgaard IS

Plant Soil 407 (1-2) 91-107 [2016-10-00; online 2016-04-15]

Loss of ncm(5) and mcm(5) wobble uridine side chains results in an altered metabolic profile.

Karlsborn T, Mahmud AK, Tükenmez H, Byström AS

Metabolomics 12 (12) 177 [2016-09-27; online 2016-09-27]

Dynamic regulation of auxin oxidase and conjugating enzymes AtDAO1 and GH3 modulates auxin homeostasis.

Mellor N, Band LR, Pěnčík A, ..., Bennett MJ, Owen MR

Proc. Natl. Acad. Sci. U.S.A. 113 (39) 11022-11027 [2016-09-27; online 2016-09-20]

Dioxygenase-encoding AtDAO1 gene controls IAA oxidation and homeostasis in Arabidopsis.

Porco S, Pěnčík A, Rashed A, ..., Bennett MJ, Ljung K

Proc. Natl. Acad. Sci. U.S.A. 113 (39) 11016-11021 [2016-09-27; online 2016-09-22]

Overlap in serum metabolic profiles between non-related diseases: Implications for LC-MS metabolomics biomarker discovery.

Lindahl A, Forshed J, Nordström A

Biochem. Biophys. Res. Commun. 478 (3) 1472-1477 [2016-09-23; online 2016-08-28]

Metabolic Profiling of Systemic Lupus Erythematosus and Comparison with Primary Sjögren's Syndrome and Systemic Sclerosis.

Bengtsson AA, Trygg J, Wuttge DM, ..., Rännar S, Lundstedt T

PLoS ONE 11 (7) e0159384 [2016-07-21; online 2016-07-21]

The epidermis coordinates auxin-induced stem growth in response to shade.

Procko C, Burko Y, Jaillais Y, ..., Long JA, Chory J

Genes Dev. 30 (13) 1529-1541 [2016-07-01; online 2016-07-13]

Multi-platform metabolomics assays for human lung lavage fluids in an air pollution exposure study.

Surowiec I, Karimpour M, Gouveia-Figueira S, ..., Trygg J, Nording ML

Anal Bioanal Chem 408 (17) 4751-4764 [2016-07-00; online 2016-04-25]

The Effects of High Steady State Auxin Levels on Root Cell Elongation in Brachypodium.

Pacheco-Villalobos D, Díaz-Moreno SM, van der Schuren A, ..., Bulone V, Hardtke CS

Plant Cell - (-) - [2016-05-05; online 2016-05-05]

Reduced mitochondrial malate dehydrogenase activity has a strong effect on photorespiratory metabolism as revealed by 13C labelling.

Lindén P, Keech O, Stenlund H, Gardeström P, Moritz T

J. Exp. Bot. 67 (10) 3123-3135 [2016-05-00; online 2016-02-19]

Metabolomics study of fatigue in patients with rheumatoid arthritis naïve to biological treatment.

Surowiec I, Gjesdal CG, Jonsson G, ..., Trygg J, Omdal R

Rheumatol. Int. 36 (5) 703-711 [2016-05-00; online 2016-01-25]

TOR Signaling and Nutrient Sensing.

Dobrenel T, Caldana C, Hanson J, ..., Veit B, Meyer C

Annu Rev Plant Biol 67 (-) 261-285 [2016-04-29; online 2016-02-26]

PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B.

Mehlem A, Palombo I, Wang X, ..., Eriksson U, Falkevall A

Diabetes 65 (4) 861-873 [2016-04-00; online 2016-01-30]

Multi-platform mass spectrometry analysis of the CSF and plasma metabolomes of rigorously matched amyotrophic lateral sclerosis, Parkinson's disease and control subjects.

Wuolikainen A, Jonsson P, Ahnlund M, ..., Andersen PM, Trupp M

Mol Biosyst 12 (4) 1287-1298 [2016-04-00; online 2016-02-18]

Connective Auxin Transport in the Shoot Facilitates Communication between Shoot Apices.

Bennett T, Hines G, van Rongen M, ..., Ljung K, Leyser O

PLoS Biol. 14 (4) e1002446 [2016-04-00; online 2016-04-27]

Local auxin metabolism regulates environment-induced hypocotyl elongation

Zheng Z, Guo Y, Novák O, ..., Noel JP, Chory J

NPLANTS 2 (4) 16025 [2016-03-21; online 2016-03-21]

Rat Prostate Tumor Cells Progress in the Bone Microenvironment to a Highly Aggressive Phenotype.

Bergström SH, Rudolfsson SH, Bergh A

Neoplasia 18 (3) 152-161 [2016-03-00; online 2016-03-20]

Quantitative Auxin Metabolite Profiling Using Stable Isotope Dilution UHPLC-MS/MS.

Novák O, Pěnčík A, Blahoušek O, Ljung K

Curr Protoc Plant Biol 1 (2) 419-430 [2016-03-00; online 2016-03-01]

Association between plasma concentrations of linoleic acid-derived oxylipins and the perceived pain scores in an exploratory study in women with chronic neck pain.

Hellström F, Gouveia-Figueira S, Nording ML, Björklund M, Fowler CJ

BMC Musculoskelet Disord 17 (-) 103 [2016-02-25; online 2016-02-25]

Quantitative proteomics reveals protein profiles underlying major transitions in aspen wood development.

Obudulu O, Bygdell J, Sundberg B, ..., Trygg J, Wingsle G

BMC Genomics 17 (-) 119 [2016-02-18; online 2016-02-18]

Bioinformatics (NBIS) [Collaborative] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre [Service]

Postprandial metabolomics: A pilot mass spectrometry and NMR study of the human plasma metabolome in response to a challenge meal.

Karimpour M, Surowiec I, Wu J, ..., Zivkovic AM, Nording ML

Anal. Chim. Acta 908 (-) 121-131 [2016-02-18; online 2016-01-31]

Bioinformatics (NBIS) [Collaborative] Bioinformatics Support and Infrastructure [Collaborative] Bioinformatics Support, Infrastructure and Training [Collaborative] Swedish Metabolomics Centre [Service]

Tissue sample stability: thawing effect on multi-organ samples

Torell F, Bennett K, Cereghini S, ..., Trygg J, Lundstedt T

Metabolomics 12 (2) - [2016-02-00; online 2015-12-31]

Metabolites in Blood for Prediction of Bacteremic Sepsis in the Emergency Room.

Kauppi AM, Edin A, Ziegler I, ..., Strålin K, Johansson A

PLoS ONE 11 (1) e0147670 [2016-01-22; online 2016-01-22]

Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light.

Pedmale UV, Huang SS, Zander M, ..., Ecker JR, Chory J

Cell 164 (1-2) 233-245 [2016-01-14; online 2016-01-05]

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease.

Missailidis C, Hällqvist J, Qureshi AR, ..., Stenvinkel P, Bergman P

PLoS ONE 11 (1) e0141738 [2016-01-11; online 2016-01-11]

Oxylipins, endocannabinoids, and related compounds in human milk: Levels and effects of storage conditions.

Wu J, Gouveia-Figueira S, Domellöf M, Zivkovic AM, Nording ML

Prostaglandins Other Lipid Mediat. 122 (-) 28-36 [2016-01-00; online 2015-12-15]

Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells.

Stäubert C, Krakowsky R, Bhuiyan H, ..., Broom O, Nordström A

Med. Oncol. 33 (1) 6 [2016-01-00; online 2015-12-23]