Wilson JF

Genetic insights into resting heart rate and its role in cardiovascular disease.

van de Vegte YJ, Eppinga RN, van der Ende MY, ..., Verweij N, van der Harst P

Nat Commun 14 (1) 4646 [2023-08-02; online 2023-08-02]

Clinical Genomics Gothenburg [Collaborative] NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis.

Medina-Gomez C, Mullin BH, Chesi A, ..., Kague E, Rivadeneira F

Commun Biol 6 (1) 691 [2023-07-04; online 2023-07-04]

Clinical Genomics Gothenburg [Collaborative]

Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk.

Shrine N, Izquierdo AG, Chen J, ..., Hall IP, Tobin MD

Nat. Genet. 55 (3) 410-422 [2023-03-00; online 2023-03-13]

NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.

Wang Z, Emmerich A, Pillon NJ, ..., Loos RJF, Hoed Md

Nat. Genet. 54 (9) 1332-1344 [2022-09-00; online 2022-09-07]

NGI Uppsala (Uppsala Genome Center) [Collaborative] National Genomics Infrastructure [Collaborative]

Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals.

Winkler TW, Rasheed H, Teumer A, ..., Pattaro C, Heid IM

Commun Biol 5 (1) 580 [2022-06-13; online 2022-06-13]

NGI SNP genotyping [Service] NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

The power of genetic diversity in genome-wide association studies of lipids.

Graham SE, Clarke SL, Wu KH, ..., Sun YV, Willer CJ

Nature 600 (7890) 675-679 [2021-12-00; online 2021-12-09]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease.

Crawford AA, Bankier S, Altmaier E, ..., Walker BR, CORtisol NETwork (CORNET) consortium

J. Hum. Genet. 66 (6) 625-636 [2021-06-00; online 2021-01-20]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.

Lagou V, Mägi R, Hottenga JJ, ..., Prokopenko I, Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC)

Nat Commun 12 (1) 24 [2021-01-05; online 2021-01-05]

NGI Stockholm (Genomics Applications) [Service] NGI Stockholm (Genomics Production) [Service] NGI Uppsala (SNP&SEQ Technology Platform) National Genomics Infrastructure

Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.

Ntalla I, Weng LC, Cartwright JH, ..., Lubitz SA, Munroe PB

Nat Commun 11 (1) 2542 [2020-05-21; online 2020-05-21]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

Associations of autozygosity with a broad range of human phenotypes.

Clark DW, Okada Y, Moore KHS, ..., Kubo M, Wilson JF

Nat Commun 10 (1) 4957 [2019-10-31; online 2019-10-31]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]

A catalog of genetic loci associated with kidney function from analyses of a million individuals.

Wuttke M, Li Y, Li M, ..., Köttgen A, Pattaro C

Nat. Genet. 51 (6) 957-972 [2019-06-00; online 2019-05-31]

NGI Uppsala (SNP&SEQ Technology Platform) [Service] National Genomics Infrastructure [Service]